MGE detailed information
MGE type: Conjugative plasmid MGE length: 66053 bp
Accession: NZ_CP046261 Location: 1..66053 Organism: Escherichia coli strain ECO2947 Replicon: plasmid p2947-NDM5
Accession: NZ_CP046261 Location: 1..66053 Organism: Escherichia coli strain ECO2947 Replicon: plasmid p2947-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GK046_RS24260 () | 1..858 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| GK046_RS24265 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| GK046_RS24270 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| GK046_RS24275 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| GK046_RS24280 () | 3383..3798 | + | 416 | Protein_5 | IS1 family transposase IS1R | Transposase |
| GK046_RS24285 () | 3834..4379 | - | 546 | Protein_6 | Tn3 family transposase TnpA_Tn3 | Transposase |
| GK046_RS24290 () | 4558..5574 | - | 1017 | WP_001310555.1 | IS5 family transposase IS5D | Transposase |
| GK046_RS24295 () | 5773..6585 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| GK046_RS24300 () | 6589..6954 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| GK046_RS24305 () | 6959..7597 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| GK046_RS24310 () | 7608..8639 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| GK046_RS24315 () | 8644..8772 | - | 129 | Protein_12 | divalent cation tolerance protein CutA | - |
| GK046_RS24320 () | 8837..9541 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GK046_RS24325 () | 10162..10396 | + | 235 | Protein_14 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GK046_RS24330 () | 10524..10805 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| GK046_RS24335 () | 10928..11278 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| GK046_RS24340 () | 11281..12243 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| GK046_RS24345 () | 12390..12683 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| GK046_RS24350 () | 12760..13443 | + | 684 | WP_000085883.1 | DNA methylase | - |
| GK046_RS24355 () | 13444..13665 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| GK046_RS24360 () | 13679..14113 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| GK046_RS24840 () | 14164..14940 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| GK046_RS24375 () | 15481..15783 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| GK046_RS24380 () | 15830..16252 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| GK046_RS24385 () | 16249..16440 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| GK046_RS24390 () | 17478..17708 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| GK046_RS24395 () | 17760..19121 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| GK046_RS24400 () | 19168..19731 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| GK046_RS24410 () | 20574..21101 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| GK046_RS24415 () | 21159..21392 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| GK046_RS24420 () | 21453..23476 | + | 2024 | Protein_31 | ParB/RepB/Spo0J family partition protein | - |
| GK046_RS24425 () | 23545..23979 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| GK046_RS24430 () | 23976..24695 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 24707..24931 | + | 225 | NuclAT_0 | - | - |
| - () | 24707..24931 | + | 225 | NuclAT_0 | - | - |
| - () | 24707..24931 | + | 225 | NuclAT_0 | - | - |
| - () | 24707..24931 | + | 225 | NuclAT_0 | - | - |
| GK046_RS24435 () | 24716..24895 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - () | 24864..24929 | + | 66 | - | - | Antitoxin Detail |
| GK046_RS24440 () | 24975..25133 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| GK046_RS24845 () | 25371..25748 | - | 378 | Protein_36 | hypothetical protein | - |
| GK046_RS24450 () | 26048..26344 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| GK046_RS24455 () | 26455..27276 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| GK046_RS24460 () | 27573..28175 | - | 603 | WP_000243713.1 | hypothetical protein | VF |
| GK046_RS24465 () | 28498..28881 | + | 384 | WP_001354030.1 | relaxosome protein TraM | - |
| GK046_RS24470 () | 29075..29746 | + | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| GK046_RS24475 () | 29883..30110 | + | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| GK046_RS24480 () | 30143..30502 | + | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
| GK046_RS24485 () | 30517..30828 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| GK046_RS24490 () | 30850..31416 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| GK046_RS24495 () | 31403..32131 | + | 729 | WP_001230772.1 | type-F conjugative transfer system secretin TraK | - |
| GK046_RS24500 () | 32131..33582 | + | 1452 | WP_000146675.1 | conjugal transfer protein TraB | - |
| GK046_RS24505 () | 33551..34138 | + | 588 | WP_001444176.1 | conjugal transfer protein TraP | - |
| GK046_RS24510 () | 34077..34445 | + | 369 | WP_001315561.1 | conjugal transfer protein TrbD | - |
| GK046_RS24515 () | 34442..34957 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| GK046_RS24520 () | 35092..35313 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| GK046_RS24525 () | 35306..35782 | + | 477 | WP_000549587.1 | hypothetical protein | - |
| GK046_RS24530 () | 35862..36080 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| GK046_RS24535 () | 36108..36455 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| GK046_RS24540 () | 36581..39211 | + | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| GK046_RS24545 () | 39208..39594 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| GK046_RS24550 () | 39591..40223 | + | 633 | WP_001203728.1 | type-F conjugative transfer system protein TraW | - |
| GK046_RS24555 () | 40220..41212 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| GK046_RS24560 () | 41242..41547 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| GK046_RS24565 () | 41556..42194 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| GK046_RS24570 () | 42191..44041 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| GK046_RS24575 () | 44068..44325 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| GK046_RS24580 () | 44318..45061 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| GK046_RS24585 () | 45075..45419 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| GK046_RS24590 () | 45538..45822 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| GK046_RS24595 () | 45809..46354 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| GK046_RS24600 () | 46284..46631 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| GK046_RS24605 () | 46579..47004 | + | 426 | WP_001444237.1 | F-type conjugal transfer protein TrbF | - |
| GK046_RS24610 () | 46991..48364 | + | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| GK046_RS24615 () | 48361..51183 | + | 2823 | WP_001007039.1 | conjugal transfer mating pair stabilization protein TraG | - |
| GK046_RS24620 () | 51199..51684 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| GK046_RS24625 () | 51733..52464 | + | 732 | WP_000782451.1 | complement resistance protein TraT | - |
| GK046_RS24630 () | 52667..53404 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| GK046_RS24635 () | 53455..55707 | + | 2253 | WP_015059147.1 | type IV conjugative transfer system coupling protein TraD | - |
| GK046_RS24640 () | 55707..60977 | + | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| GK046_RS24645 () | 60997..61743 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| GK046_RS24650 () | 61802..62662 | + | 861 | WP_000704523.1 | putative protein YcjY | VF |
| GK046_RS24655 () | 62765..63325 | + | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| GK046_RS24660 () | 63454..63666 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| GK046_RS24665 () | 63911..64372 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| GK046_RS24670 () | 64418..64627 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| GK046_RS24675 () | 64665..65255 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| GK046_RS24680 () | 65495..65749 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|