MGE detailed information
MGE type: Conjugative plasmid MGE length: 163406 bp
Accession: NZ_CP045210 Location: 1..163406 Organism: Escherichia coli strain 4 Replicon: plasmid pO113-4
Accession: NZ_CP045210 Location: 1..163406 Organism: Escherichia coli strain 4 Replicon: plasmid pO113-4
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GC226_RS23820 (GC226_24040) | 1..1032 | - | 1032 | WP_000907876.1 | plasmid replication initiator RepA | - |
| GC226_RS23825 (GC226_24050) | 1734..2375 | + | 642 | WP_000335846.1 | transcription termination/antitermination NusG family protein | - |
| GC226_RS23830 (GC226_24055) | 2516..3181 | + | 666 | WP_000154144.1 | hypothetical protein | - |
| GC226_RS23835 (GC226_24065) | 3448..4068 | + | 621 | WP_000176499.1 | DUF1449 family protein | - |
| GC226_RS23840 (GC226_24070) | 4095..5789 | + | 1695 | WP_000482662.1 | flotillin family protein | - |
| GC226_RS23845 (GC226_24075) | 5870..6112 | + | 243 | WP_077888482.1 | PilI type IV pilus biogenesis protein | - |
| GC226_RS23850 (GC226_24080) | 6262..6564 | + | 303 | Protein_6 | hypothetical protein | - |
| GC226_RS23855 (GC226_24085) | 6721..7791 | + | 1071 | WP_001170190.1 | hypothetical protein | VF |
| GC226_RS23860 (GC226_24090) | 7796..8233 | + | 438 | WP_000539684.1 | type IV pilus biogenesis protein PilM | - |
| GC226_RS23865 (GC226_24095) | 8264..9883 | + | 1620 | WP_001034996.1 | Outer membrane lipoprotein BfpB | VF |
| GC226_RS23870 (GC226_24100) | 9904..11199 | + | 1296 | WP_000129891.1 | type 4b pilus protein PilO2 | - |
| GC226_RS23875 (GC226_24105) | 11189..11641 | + | 453 | WP_001112923.1 | type IV pilus biogenesis protein PilP | - |
| GC226_RS23880 (GC226_24110) | 11726..13234 | + | 1509 | WP_000886636.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| GC226_RS23885 (GC226_24115) | 13236..14336 | + | 1101 | WP_000670139.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| GC226_RS23890 (GC226_24120) | 14410..14946 | + | 537 | WP_001011156.1 | type 4 pilus major pilin | - |
| GC226_RS23895 (GC226_24125) | 15000..15473 | + | 474 | WP_000870986.1 | hypothetical protein | VF |
| GC226_RS23900 (GC226_24130) | 15492..16127 | + | 636 | WP_000478595.1 | prepilin peptidase | - |
| GC226_RS23905 (GC226_24135) | 16132..17496 | + | 1365 | WP_001168071.1 | hypothetical protein | VF |
| GC226_RS23910 (GC226_24145) | 17754..17912 | + | 159 | Protein_18 | integrase | - |
| GC226_RS23915 (GC226_24150) | 17954..18244 | + | 291 | WP_000681897.1 | hypothetical protein | - |
| GC226_RS23920 (GC226_24155) | 18336..18656 | - | 321 | WP_000695056.1 | hypothetical protein | - |
| GC226_RS23925 (GC226_24160) | 18916..19737 | + | 822 | WP_000804094.1 | hypothetical protein | - |
| GC226_RS23930 (GC226_24165) | 19827..21028 | + | 1202 | Protein_22 | conjugal transfer protein TraF | - |
| GC226_RS23935 (GC226_24170) | 21387..21839 | + | 453 | WP_001081198.1 | DotD/TraH family lipoprotein | - |
| GC226_RS23940 (GC226_24175) | 21864..22679 | + | 816 | WP_228400226.1 | hypothetical protein | VF |
| GC226_RS23945 (GC226_24180) | 22663..23811 | + | 1149 | WP_000625247.1 | putative protein YggR | VF |
| GC226_RS23950 (GC226_24185) | 23808..24098 | + | 291 | WP_000817799.1 | hypothetical protein | - |
| GC226_RS23955 (GC226_24190) | 24162..28178 | + | 4017 | WP_033811931.1 | DUF5710 domain-containing protein | - |
| GC226_RS23960 (GC226_24195) | 28195..28545 | + | 351 | WP_001056369.1 | hypothetical protein | - |
| GC226_RS23965 (GC226_24200) | 28557..29252 | + | 696 | WP_001287263.1 | DotI/IcmL family type IV secretion protein | - |
| GC226_RS23970 (GC226_24205) | 29263..30237 | + | 975 | WP_001165562.1 | hypothetical protein | VF |
| GC226_RS23975 (GC226_24210) | 30241..31572 | + | 1332 | WP_001272010.1 | conjugal transfer protein TraO | - |
| GC226_RS23980 (GC226_24215) | 31569..32282 | + | 714 | WP_000787005.1 | conjugal transfer protein TraP | - |
| GC226_RS23985 (GC226_24220) | 32279..32809 | + | 531 | WP_000987018.1 | conjugal transfer protein TraQ | - |
| GC226_RS23990 (GC226_24225) | 32856..33254 | + | 399 | WP_000086066.1 | hypothetical protein | - |
| GC226_RS23995 | 33311..33463 | + | 153 | Protein_35 | TraS | - |
| GC226_RS24000 (GC226_24235) | 33477..34295 | + | 819 | WP_072094468.1 | conjugal transfer protein TraT | - |
| GC226_RS24005 (GC226_24240) | 34350..34709 | + | 360 | WP_000380399.1 | hypothetical protein | - |
| GC226_RS24010 (GC226_24245) | 34706..35089 | + | 384 | WP_011310086.1 | hypothetical protein | - |
| GC226_RS24015 (GC226_24250) | 35264..38308 | + | 3045 | WP_001024761.1 | hypothetical protein | - |
| GC226_RS24020 (GC226_24255) | 38308..38925 | + | 618 | WP_000286857.1 | hypothetical protein | - |
| GC226_RS24025 (GC226_24260) | 38886..40091 | + | 1206 | WP_001189539.1 | conjugal transfer protein TraW | - |
| GC226_RS24030 (GC226_24265) | 40088..40657 | + | 570 | WP_000650755.1 | conjugal transfer protein TraX | - |
| GC226_RS24035 (GC226_24270) | 40730..42895 | + | 2166 | WP_000691805.1 | DotA/TraY family protein | - |
| GC226_RS24040 (GC226_24275) | 42966..43616 | + | 651 | WP_001098359.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| GC226_RS24045 (GC226_24280) | 43890..45476 | + | 1587 | WP_000004566.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| GC226_RS24050 (GC226_24285) | 45614..45766 | - | 153 | WP_001367784.1 | Hok/Gef family protein | - |
| GC226_RS24055 (GC226_24295) | 46207..46884 | + | 678 | WP_032320235.1 | IS66 family transposase ISCro1 | Transposase |
| GC226_RS24060 (GC226_24300) | 46884..47231 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| GC226_RS24065 (GC226_24305) | 47251..48822 | + | 1572 | WP_228400223.1 | IS66 family transposase ISCro1 | Transposase |
| GC226_RS24070 (GC226_24310) | 48825..49049 | + | 225 | WP_032320247.1 | hypothetical protein | - |
| GC226_RS24075 (GC226_24315) | 49142..50677 | - | 1536 | WP_001373098.1 | phosphoethanolamine transferase | - |
| GC226_RS24080 (GC226_24320) | 50878..51333 | - | 456 | WP_001205143.1 | DUF2569 family protein | - |
| GC226_RS24085 (GC226_24325) | 51421..52044 | - | 624 | WP_001158018.1 | hypothetical protein | - |
| GC226_RS24090 (GC226_24330) | 52203..52616 | + | 414 | WP_000598952.1 | thermonuclease family protein | - |
| GC226_RS24095 (GC226_24335) | 53063..57142 | + | 4080 | WP_228400224.1 | Serine protease SepA autotransporter | VF |
| GC226_RS25135 | 57390..57515 | - | 126 | WP_001344629.1 | hypothetical protein | - |
| GC226_RS24100 (GC226_24345) | 57649..58014 | + | 366 | WP_228400225.1 | hypothetical protein | - |
| GC226_RS24105 (GC226_24350) | 58024..58215 | + | 192 | WP_000264906.1 | hypothetical protein | - |
| GC226_RS24110 (GC226_24355) | 58243..58554 | + | 312 | WP_000203481.1 | hypothetical protein | - |
| GC226_RS24115 (GC226_24370) | 59337..60608 | + | 1272 | WP_000121915.1 | IncI1-type conjugal transfer protein TrbA | - |
| GC226_RS24120 (GC226_24375) | 60605..61723 | + | 1119 | WP_000155605.1 | DsbC family protein | - |
| GC226_RS24125 (GC226_24380) | 61704..64007 | + | 2304 | WP_077173457.1 | F-type conjugative transfer protein TrbC | - |
| GC226_RS24130 (GC226_24385) | 64133..64435 | + | 303 | WP_000334995.1 | hypothetical protein | - |
| GC226_RS24135 (GC226_24390) | 64533..64964 | - | 432 | WP_001335086.1 | cell envelope integrity TolA C-terminal domain-containing protein | - |
| GC226_RS24140 (GC226_24395) | 65032..67743 | - | 2712 | WP_000991390.1 | Protein TraI | Relaxase |
| GC226_RS24145 (GC226_24400) | 67755..68087 | - | 333 | WP_001291058.1 | plasmid mobilization protein MobA | - |
| GC226_RS24150 (GC226_24405) | 68319..68654 | + | 336 | WP_000157095.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| GC226_RS24155 (GC226_24410) | 68739..69587 | - | 849 | WP_001077013.1 | DUF4942 domain-containing protein | - |
| GC226_RS24160 (GC226_24425) | 70166..70417 | + | 252 | WP_000148286.1 | helix-turn-helix transcriptional regulator | - |
| GC226_RS24165 (GC226_24430) | 70448..70681 | - | 234 | WP_001370006.1 | hypothetical protein | - |
| GC226_RS24170 (GC226_24435) | 70681..71607 | - | 927 | WP_000038346.1 | Recombination-promoting nuclease RpnA | VF |
| GC226_RS24175 (GC226_24440) | 71672..71938 | - | 267 | WP_001247860.1 | hypothetical protein | - |
| GC226_RS24180 (GC226_24445) | 72031..72465 | - | 435 | WP_000218848.1 | hypothetical protein | - |
| GC226_RS24185 (GC226_24460) | 73198..73698 | - | 501 | WP_000117617.1 | antirestriction protein ArdA | - |
| GC226_RS24190 (GC226_24470) | 74163..74759 | - | 597 | WP_000978008.1 | hypothetical protein | - |
| GC226_RS24195 (GC226_24475) | 74756..75475 | - | 720 | WP_001276261.1 | plasmid SOS inhibition protein A | - |
| GC226_RS24200 (GC226_24480) | 75472..75906 | - | 435 | WP_000845900.1 | conjugation system SOS inhibitor PsiB | - |
| GC226_RS24205 (GC226_24485) | 75961..77919 | - | 1959 | WP_000117306.1 | ParB/RepB/Spo0J family partition protein | - |
| GC226_RS24210 (GC226_24490) | 77979..78212 | - | 234 | WP_000006027.1 | DUF905 domain-containing protein | - |
| GC226_RS24215 (GC226_24495) | 78270..78803 | - | 534 | WP_001276132.1 | single-stranded DNA-binding protein | - |
| GC226_RS24220 (GC226_24500) | 78846..79523 | - | 678 | Protein_81 | hypothetical protein | - |
| GC226_RS24225 (GC226_24505) | 79568..80086 | - | 519 | WP_224065154.1 | DUF1380 family protein | - |
| GC226_RS24230 (GC226_24510) | 80016..80237 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| GC226_RS24235 (GC226_24515) | 80238..80921 | - | 684 | WP_000086114.1 | DNA methylase | - |
| GC226_RS24240 (GC226_24520) | 80998..81303 | - | 306 | WP_032236829.1 | hypothetical protein | - |
| GC226_RS24245 (GC226_24525) | 81307..82209 | - | 903 | WP_077629773.1 | DUF1281 domain-containing protein | - |
| GC226_RS24250 (GC226_24535) | 82628..82876 | + | 249 | WP_000618108.1 | DinI-like family protein | - |
| GC226_RS24255 (GC226_24540) | 82873..83310 | + | 438 | WP_000109074.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| GC226_RS24260 (GC226_24545) | 83310..84580 | + | 1271 | Protein_89 | translesion error-prone DNA polymerase V subunit UmuC | - |
| GC226_RS24265 (GC226_24555) | 84784..85410 | + | 627 | WP_000587689.1 | ParA family plasmid-partitioning AAA ATPase | - |
| GC226_RS24270 | 85407..85709 | + | 303 | WP_001245884.1 | hypothetical protein | - |
| GC226_RS24275 (GC226_24570) | 86106..86357 | + | 252 | WP_031322317.1 | hypothetical protein | - |
| GC226_RS24280 (GC226_24575) | 86357..86947 | + | 591 | WP_000194580.1 | hypothetical protein | - |
| GC226_RS24285 (GC226_24580) | 86967..87313 | - | 347 | Protein_94 | DUF6404 family protein | - |
| GC226_RS24290 (GC226_24585) | 87432..87779 | + | 348 | WP_000762580.1 | colicin E1 family microcin immunity protein | - |
| GC226_RS24295 (GC226_24590) | 87797..89677 | - | 1881 | WP_001283355.1 | colicin Ia central receptor-binding domain-containing protein | - |
| GC226_RS24300 (GC226_24595) | 89956..90648 | - | 693 | Protein_97 | hypothetical protein | - |
| GC226_RS24305 (GC226_24600) | 90644..90853 | - | 210 | Protein_98 | IS21 family transposase IS21 | Transposase |
| GC226_RS24310 (GC226_24610) | 91350..93323 | + | 1974 | WP_024177478.1 | Hemin receptor | VF |
| GC226_RS24315 (GC226_24615) | 93342..94133 | + | 792 | WP_000977390.1 | DUF4198 domain-containing protein | - |
| GC226_RS24320 (GC226_24625) | 94638..95057 | + | 420 | WP_000422695.1 | IS66 family transposase ISEc23 | Transposase |
| GC226_RS24325 (GC226_24630) | 95054..95404 | + | 351 | WP_000624657.1 | IS66 family transposase IS682 | Transposase |
| GC226_RS24330 (GC226_24635) | 95435..97027 | + | 1593 | WP_136760732.1 | IS66 family transposase ISEc47 | Transposase |
| GC226_RS24335 (GC226_24640) | 97057..97230 | + | 174 | Protein_104 | DUF4113 domain-containing protein | - |
| GC226_RS24340 (GC226_24645) | 97232..97648 | - | 417 | WP_001278809.1 | plasmid partitioning/stability family protein | - |
| GC226_RS24345 (GC226_24650) | 97641..98621 | - | 981 | WP_000688508.1 | plasmid segregation protein ParM | - |
| GC226_RS24350 (GC226_24655) | 99036..99344 | - | 309 | WP_000030199.1 | hypothetical protein | - |
| GC226_RS24355 (GC226_24660) | 99431..100075 | - | 645 | WP_001144036.1 | ParA family protein | - |
| GC226_RS24360 (GC226_24665) | 100255..101061 | - | 807 | WP_000016966.1 | site-specific integrase | - |
| GC226_RS24365 (GC226_24670) | 101062..101367 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| GC226_RS24370 (GC226_24675) | 101369..101587 | - | 219 | WP_000813639.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| GC226_RS24375 (GC226_24680) | 102183..102443 | + | 261 | WP_000343083.1 | hypothetical protein | - |
| GC226_RS24380 (GC226_24685) | 102440..103030 | + | 591 | WP_000194569.1 | hypothetical protein | - |
| GC226_RS24385 (GC226_24690) | 103048..103395 | - | 348 | WP_000142426.1 | DUF6404 family protein | - |
| GC226_RS24390 (GC226_24695) | 103865..104185 | - | 321 | WP_001365556.1 | colicin-like pore-forming protein | - |
| GC226_RS24395 (GC226_24700) | 104295..105026 | - | 732 | WP_000850413.1 | conjugal transfer complement resistance protein TraT | - |
| GC226_RS24400 | 105303..105455 | - | 153 | Protein_117 | IS481 family transposase | - |
| GC226_RS24405 (GC226_24720) | 106197..107174 | + | 978 | WP_001369978.1 | RepB family plasmid replication initiator protein | - |
| GC226_RS24410 (GC226_24725) | 107413..107695 | - | 283 | Protein_119 | ISL3 family transposase ISEc53 | Transposase |
| GC226_RS24415 (GC226_24730) | 107852..108082 | - | 231 | WP_032279745.1 | hypothetical protein | - |
| GC226_RS24420 (GC226_24740) | 108212..108535 | - | 324 | WP_235176086.1 | Transcriptional repressor MprA | VF |
| GC226_RS24425 | 108584..108760 | - | 177 | Protein_122 | Transcriptional repressor MprA | VF |
| GC226_RS24430 (GC226_24745) | 108827..110266 | - | 1440 | WP_001213534.1 | Hemolysin secretion protein D, chromosomal | VF |
| GC226_RS24435 (GC226_24750) | 110270..112390 | - | 2121 | WP_072094473.1 | Alpha-hemolysin translocation ATP-binding protein HlyB | VF |
| GC226_RS24440 (GC226_24755) | 112440..115436 | - | 2997 | WP_000217748.1 | Hemolysin, chromosomal | VF |
| GC226_RS24445 (GC226_24760) | 115438..115953 | - | 516 | WP_001365635.1 | RTX-I toxin-activating lysine-acyltransferase ApxIC | VF |
| GC226_RS24450 (GC226_24770) | 116381..117184 | - | 804 | WP_000899428.1 | Outer membrane protein A | VF |
| GC226_RS24455 (GC226_24775) | 117209..121516 | - | 4308 | WP_024177480.1 | Autotransporter adhesin SadA | VF |
| GC226_RS24460 (GC226_24780) | 121738..122022 | - | 285 | WP_000439678.1 | Major pilu subunit operon regulatory protein PapB | VF |
| GC226_RS24465 (GC226_24790) | 122630..123177 | + | 548 | Protein_130 | transposase | - |
| GC226_RS24470 (GC226_24800) | 123507..123941 | + | 435 | Protein_131 | IS110 family transposase ISEc21 | Transposase |
| GC226_RS24475 (GC226_24805) | 124028..125553 | + | 1526 | Protein_132 | IS3 family transposase | - |
| GC226_RS24480 (GC226_24810) | 125658..126287 | + | 630 | Protein_133 | transposase | - |
| GC226_RS24485 (GC226_24815) | 126307..126655 | + | 349 | Protein_134 | integrase core domain-containing protein | - |
| GC226_RS24490 (GC226_24820) | 127020..128576 | + | 1557 | WP_000554412.1 | L-lactate permease | - |
| GC226_RS24495 (GC226_24825) | 128627..129346 | + | 720 | WP_001102092.1 | (Fe-S)-binding protein | - |
| GC226_RS24500 (GC226_24830) | 129357..130772 | + | 1416 | WP_000054160.1 | LutB/LldF family L-lactate oxidation iron-sulfur protein | - |
| GC226_RS24505 (GC226_24835) | 130777..131475 | + | 699 | WP_000431492.1 | lactate utilization protein C | - |
| GC226_RS24510 (GC226_24840) | 131516..131752 | - | 237 | WP_001369996.1 | hypothetical protein | - |
| GC226_RS24515 (GC226_24845) | 131823..132284 | - | 462 | Protein_140 | IS3 family transposase ISKpn8 | Transposase |
| GC226_RS24520 (GC226_24850) | 132400..132672 | - | 273 | WP_052077017.1 | hypothetical protein | - |
| GC226_RS24525 (GC226_24855) | 132739..132930 | - | 192 | WP_000264906.1 | hypothetical protein | - |
| GC226_RS24530 (GC226_24860) | 132940..133305 | - | 366 | WP_001536659.1 | hypothetical protein | - |
| GC226_RS25140 | 133439..133564 | + | 126 | WP_001344629.1 | hypothetical protein | - |
| GC226_RS24535 (GC226_24870) | 133812..137714 | - | 3903 | WP_047091594.1 | Serine protease EspP | VF |
| GC226_RS24540 (GC226_24875) | 138094..138597 | - | 504 | Protein_146 | thermonuclease family protein | - |
| GC226_RS24545 (GC226_24880) | 138756..139433 | + | 678 | WP_044527425.1 | hypothetical protein | - |
| GC226_RS24550 (GC226_24890) | 139923..140243 | - | 321 | WP_000220092.1 | hypothetical protein | - |
| GC226_RS24555 (GC226_24895) | 140301..141463 | - | 1163 | Protein_149 | IS3-like element IS3 family transposase | - |
| GC226_RS24560 | 141530..141619 | - | 90 | Protein_150 | transposase | - |
| GC226_RS24565 (GC226_24900) | 141873..143366 | + | 1494 | WP_077173497.1 | Adhesin YadA | VF |
| GC226_RS24570 (GC226_24905) | 143575..144680 | + | 1106 | Protein_152 | IS3 family transposase | - |
| GC226_RS24575 (GC226_24915) | 144988..147075 | + | 2088 | WP_001223214.1 | bifunctional siderophore receptor/adhesin Iha | - |
| GC226_RS24580 (GC226_24920) | 147336..147758 | - | 423 | WP_001212725.1 | Exc2 family lipoprotein | - |
| GC226_RS24585 (GC226_24925) | 148093..148260 | - | 168 | Protein_155 | IS110 family transposase | - |
| GC226_RS24590 (GC226_24930) | 148337..148525 | + | 189 | Protein_156 | IS66 family transposase ISEc47 | Transposase |
| GC226_RS24595 (GC226_24935) | 148529..148738 | - | 210 | Protein_157 | hypothetical protein | - |
| GC226_RS24600 (GC226_24940) | 148809..149234 | - | 426 | WP_001373081.1 | subtilase AB5 cytotoxin subunit B | - |
| GC226_RS24605 (GC226_24945) | 149251..150294 | - | 1044 | WP_000912970.1 | subtilase AB5 cytotoxin subunit A | - |
| GC226_RS24610 (GC226_24950) | 150348..150545 | - | 198 | Protein_160 | IS66 family transposase IS682 | Transposase |
| GC226_RS24615 (GC226_24955) | 150583..152175 | - | 1593 | WP_000080208.1 | IS66 family transposase ISEc47 | Transposase |
| GC226_RS24620 (GC226_24960) | 152206..152556 | - | 351 | WP_000624657.1 | IS66 family transposase IS682 | Transposase |
| GC226_RS24625 (GC226_24965) | 152553..152972 | - | 420 | WP_000422688.1 | IS66 family transposase ISEc23 | Transposase |
| GC226_RS24630 (GC226_24970) | 153471..153659 | - | 189 | WP_169301900.1 | hypothetical protein | - |
| GC226_RS24635 | 154279..161745 | - | 7467 | Protein_165 | tRNA nuclease CdiA | VF |
| GC226_RS24640 (GC226_24985) | 162198..162437 | - | 240 | WP_011310132.1 | winged helix-turn-helix transcriptional regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|