MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 136532 bp
Accession: NZ_CP045209 Location: 3997532..4134063 Organism: Escherichia coli strain 4 Replicon: chromosome
Accession: NZ_CP045209 Location: 3997532..4134063 Organism: Escherichia coli strain 4 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GC226_RS19420 (3992834) | 3992834..3993574 | - | 741 | WP_001367953.1 | outer membrane beta-barrel protein | - |
| GC226_RS19425 (3993962) | 3993962..3995788 | + | 1827 | WP_001106664.1 | two-component system sensor histidine kinase AtoS | - |
| GC226_RS19430 (3995785) | 3995785..3997170 | + | 1386 | WP_000125284.1 | acetoacetate metabolism transcriptional regulator AtoC | - |
| GC226_RS19435 (3997366) | 3997366..3998028 | + | 663 | WP_000850528.1 | acetate CoA-transferase subunit alpha | - |
| GC226_RS19440 (3998028) | 3998028..3998678 | + | 651 | WP_228400130.1 | acetate CoA-transferase subunit beta | - |
| GC226_RS19445 (3998675) | 3998675..3999997 | + | 1323 | WP_000580275.1 | TIGR00366 family protein | - |
| GC226_RS19450 (4000028) | 4000028..4001212 | + | 1185 | WP_000786522.1 | acetyl-CoA acetyltransferase | - |
| GC226_RS19455 (4001622) | 4001622..4002275 | - | 654 | Protein_3781 | IS66 family transposase ISEc23 | Transposase |
| GC226_RS19460 (4002546) | 4002546..4002784 | + | 239 | Protein_3782 | IS66 family insertion sequence element accessory protein TnpB | - |
| GC226_RS19470 (4003598) | 4003598..4003791 | + | 194 | Protein_3783 | hypothetical protein | - |
| GC226_RS19475 (4004592) | 4004592..4004928 | - | 337 | Protein_3784 | hypothetical protein | - |
| GC226_RS19480 (4005588) | 4005588..4005803 | - | 216 | Protein_3785 | hypothetical protein | - |
| GC226_RS19485 (4007257) | 4007257..4009344 | + | 2088 | WP_001223358.1 | bifunctional siderophore receptor/adhesin Iha | - |
| GC226_RS19490 (4009485) | 4009485..4009676 | - | 192 | Protein_3787 | IS256 family transposase ISEic2 | Transposase |
| GC226_RS19495 (4009690) | 4009690..4011534 | - | 1845 | WP_000593011.1 | Vitamin B12 transporter BtuB | VF |
| GC226_RS19500 (4012435) | 4012435..4012692 | - | 258 | WP_001032733.1 | hypothetical protein | - |
| GC226_RS19505 (4012761) | 4012761..4014458 | - | 1698 | WP_228400131.1 | sulfatase | - |
| GC226_RS19510 (4014553) | 4014553..4015689 | - | 1137 | WP_001228923.1 | Outer membrane porin protein OmpD | VF |
| GC226_RS19515 (4016365) | 4016365..4016573 | + | 209 | Protein_3792 | IS66 family insertion sequence element accessory protein TnpB | - |
| GC226_RS19520 (4016560) | 4016560..4016749 | + | 190 | Protein_3793 | IS66 family insertion sequence element accessory protein TnpB | - |
| GC226_RS19525 (4016752) | 4016752..4016940 | - | 189 | WP_000520190.1 | DUF1187 family protein | - |
| GC226_RS19530 (4017463) | 4017463..4017604 | + | 142 | Protein_3795 | IS481 family transposase | - |
| GC226_RS19535 (4017826) | 4017826..4018563 | + | 738 | WP_000634448.1 | AraC family transcriptional regulator | - |
| GC226_RS19540 (4019462) | 4019462..4023556 | + | 4095 | WP_228400132.1 | Serine protease SepA autotransporter | VF |
| GC226_RS25125 (4023804) | 4023804..4023929 | - | 126 | WP_001344629.1 | hypothetical protein | - |
| GC226_RS19545 (4024063) | 4024063..4024428 | + | 366 | WP_228400133.1 | hypothetical protein | - |
| GC226_RS19550 (4024438) | 4024438..4024629 | + | 192 | WP_000264910.1 | hypothetical protein | - |
| GC226_RS19555 (4024663) | 4024663..4024872 | + | 210 | WP_000323309.1 | hypothetical protein | - |
| GC226_RS19560 (4024899) | 4024899..4025258 | - | 360 | Protein_3802 | IS66 family transposase ISCro1 | Transposase |
| GC226_RS19565 (4025370) | 4025370..4026014 | - | 645 | WP_001376509.1 | hypothetical protein | - |
| GC226_RS19570 (4026035) | 4026035..4026304 | - | 270 | WP_000226517.1 | PerC family transcriptional regulator | - |
| GC226_RS19575 (4026383) | 4026383..4027021 | - | 639 | WP_000502848.1 | ParB N-terminal domain-containing protein | - |
| GC226_RS19580 (4027006) | 4027006..4028238 | - | 1233 | Protein_3806 | phosphoadenosine phosphosulfate reductase | - |
| GC226_RS19585 (4028738) | 4028738..4031419 | - | 2682 | WP_228400134.1 | AAA domain-containing protein | - |
| GC226_RS19590 (4031660) | 4031660..4031840 | - | 181 | Protein_3808 | hypothetical protein | VF |
| GC226_RS19595 (4032171) | 4032171..4032485 | - | 315 | Protein_3809 | hypothetical protein | VF |
| GC226_RS19600 (4032540) | 4032540..4032844 | - | 305 | Protein_3810 | hypothetical protein | - |
| GC226_RS19605 (4032910) | 4032910..4034655 | - | 1746 | WP_024177317.1 | 3'-5' exonuclease | - |
| GC226_RS19610 (4034833) | 4034833..4035447 | - | 615 | WP_267132473.1 | Attachment invasion locus protein | VF |
| GC226_RS19615 (4035588) | 4035588..4035950 | - | 363 | Protein_3813 | type VI secretion system baseplate subunit TssE | - |
| GC226_RS19620 (4035951) | 4035951..4036265 | - | 315 | WP_000931686.1 | hypothetical protein | - |
| GC226_RS19625 (4036370) | 4036370..4036606 | - | 237 | WP_000500956.1 | hypothetical protein | - |
| GC226_RS19630 (4036593) | 4036593..4045724 | - | 9132 | WP_228400135.1 | 16S rRNA endonuclease CdiA | VF |
| GC226_RS19635 (4045740) | 4045740..4046267 | - | 528 | WP_228400136.1 | Leukotoxin-activating lysine-acyltransferase LtxC | VF |
| GC226_RS19640 (4046277) | 4046277..4047356 | - | 1080 | WP_223716279.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| GC226_RS19645 (4047354) | 4047354..4047929 | - | 576 | Protein_3819 | POTRA domain-containing protein | - |
| GC226_RS19650 (4048606) | 4048606..4048797 | + | 192 | WP_001287885.1 | DUF4222 domain-containing protein | - |
| GC226_RS19655 (4048850) | 4048850..4049083 | - | 234 | WP_000124190.1 | hypothetical protein | - |
| GC226_RS19660 (4049179) | 4049179..4049802 | - | 624 | WP_001366001.1 | hypothetical protein | - |
| GC226_RS19665 (4049891) | 4049891..4050388 | - | 498 | WP_021552435.1 | hypothetical protein | - |
| GC226_RS19670 (4050738) | 4050738..4051304 | - | 567 | WP_000287892.1 | inovirus-type Gp2 protein | - |
| GC226_RS19675 (4051326) | 4051326..4051568 | - | 243 | WP_224065199.1 | inovirus-type Gp2 protein | - |
| GC226_RS19680 (4051607) | 4051607..4052763 | + | 1157 | WP_085948469.1 | IS3 family transposase ISSd1 | Transposase |
| GC226_RS19685 (4053037) | 4053037..4053462 | - | 426 | WP_047084620.1 | putative zinc ribbon protein | - |
| GC226_RS19690 (4053459) | 4053459..4053842 | - | 384 | WP_000271013.1 | putative zinc ribbon protein | - |
| GC226_RS19695 (4054103) | 4054103..4054672 | - | 570 | WP_000221481.1 | inovirus Gp2 family protein | - |
| GC226_RS19700 (4054876) | 4054876..4055073 | + | 198 | WP_000236763.1 | hypothetical protein | - |
| GC226_RS19705 (4055419) | 4055419..4055568 | - | 150 | WP_071528427.1 | Hha/YmoA family nucleoid-associated regulatory protein | - |
| GC226_RS19710 (4056320) | 4056320..4056526 | + | 207 | WP_000632607.1 | AlpA family transcriptional regulator | - |
| GC226_RS19715 (4056607) | 4056607..4056897 | + | 291 | Protein_3833 | malate transporter | - |
| GC226_RS19720 (4056970) | 4056970..4058147 | + | 1178 | WP_085968792.1 | IS3 family transposase ISCfr6 | Transposase |
| GC226_RS19725 (4058156) | 4058156..4058476 | + | 321 | Protein_3835 | hypothetical protein | - |
| GC226_RS19730 (4058798) | 4058798..4060282 | - | 1485 | WP_001297234.1 | YfjI family protein | - |
| GC226_RS19735 (4061510) | 4061510..4062382 | + | 873 | WP_001069680.1 | GTPase family protein | - |
| GC226_RS19740 (4062710) | 4062710..4065829 | + | 3120 | WP_228400137.1 | autotransporter adhesin Ag43 | - |
| GC226_RS19745 (4065950) | 4065950..4068466 | + | 2517 | WP_001315618.1 | hypothetical protein | - |
| GC226_RS19750 (4068542) | 4068542..4068997 | + | 456 | Protein_3840 | IrmA family protein | - |
| GC226_RS19755 (4069076) | 4069076..4069309 | + | 234 | WP_001119729.1 | DUF905 family protein | - |
| GC226_RS19760 (4069409) | 4069409..4070227 | + | 819 | WP_001234620.1 | DUF932 domain-containing protein | - |
| GC226_RS19765 (4070282) | 4070282..4070767 | + | 486 | WP_001562321.1 | antirestriction protein | - |
| GC226_RS19770 (4070783) | 4070783..4071259 | + | 477 | WP_001186726.1 | RadC family protein | - |
| GC226_RS19775 (4071322) | 4071322..4071543 | + | 222 | WP_000692311.1 | DUF987 domain-containing protein | - |
| GC226_RS19780 (4071706) | 4071706..4072080 | + | 375 | WP_001280952.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin Detail |
| GC226_RS19785 (4072127) | 4072127..4072504 | + | 378 | WP_000854902.1 | TA system toxin CbtA family protein | Toxin Detail |
| GC226_RS19790 (4072501) | 4072501..4072989 | + | 489 | WP_000779175.1 | DUF5983 family protein | - |
| GC226_RS19795 (4073001) | 4073001..4073198 | + | 198 | WP_000839249.1 | DUF957 domain-containing protein | - |
| GC226_RS19800 (4073283) | 4073283..4074125 | + | 843 | WP_001280537.1 | DUF4942 domain-containing protein | - |
| GC226_RS19805 (4074468) | 4074468..4075004 | - | 537 | WP_000942795.1 | Type II secretion system protein M | VF |
| GC226_RS19810 (4075006) | 4075006..4076184 | - | 1179 | WP_000094989.1 | Type II secretion system protein L | VF |
| GC226_RS19815 (4076181) | 4076181..4077158 | - | 978 | WP_000633239.1 | Putative type II secretion system protein K | VF |
| GC226_RS19820 (4077155) | 4077155..4077760 | - | 606 | WP_001255030.1 | Type II secretion system protein J | VF |
| GC226_RS19825 (4077757) | 4077757..4078128 | - | 372 | WP_000820125.1 | Type II secretion system protein I | VF |
| GC226_RS19830 (4078125) | 4078125..4078688 | - | 564 | WP_001115139.1 | Type II secretion system protein H | VF |
| GC226_RS19835 (4078692) | 4078692..4079147 | - | 456 | WP_001087296.1 | Type II secretion system protein G | VF |
| GC226_RS19840 (4079164) | 4079164..4080387 | - | 1224 | Protein_3858 | Type II secretion system protein F | VF |
| GC226_RS19845 (4080387) | 4080387..4081880 | - | 1494 | WP_000249368.1 | Type II secretion system protein E | VF |
| GC226_RS19850 (4081880) | 4081880..4083940 | - | 2061 | WP_000498824.1 | Type II secretion system protein D | VF |
| GC226_RS19855 (4083970) | 4083970..4084929 | - | 960 | WP_001317325.1 | Type II secretion system protein C | VF |
| GC226_RS19860 (4084947) | 4084947..4085357 | - | 411 | WP_001349452.1 | type II secretion system pilot lipoprotein GspS-beta | - |
| GC226_RS19865 (4085423) | 4085423..4086232 | - | 810 | WP_001317326.1 | Leader peptidase PppA | VF |
| GC226_RS19870 (4086372) | 4086372..4090940 | - | 4569 | WP_001034504.1 | hypothetical protein | VF |
| GC226_RS19875 (4091425) | 4091425..4093107 | - | 1683 | WP_000259303.1 | glycolate permease GlcA | - |
| GC226_RS19880 (4093463) | 4093463..4095634 | - | 2172 | WP_000084053.1 | malate synthase G | - |
| GC226_RS19885 (4095656) | 4095656..4096060 | - | 405 | WP_000853256.1 | GlcG family protein | - |
| GC226_RS19890 (4096065) | 4096065..4097288 | - | 1224 | WP_001194682.1 | glycolate oxidase subunit GlcF | - |
| GC226_RS19895 (4097299) | 4097299..4098351 | - | 1053 | WP_000943059.1 | glycolate oxidase subunit GlcE | - |
| GC226_RS19900 (4098351) | 4098351..4099850 | - | 1500 | WP_000026117.1 | glycolate oxidase subunit GlcD | - |
| GC226_RS19905 (4100101) | 4100101..4100865 | + | 765 | WP_001297764.1 | transcriptional regulator GlcC | - |
| GC226_RS19910 (4100872) | 4100872..4102014 | - | 1143 | WP_000388786.1 | protein YghO | - |
| GC226_RS19915 (4102385) | 4102385..4104106 | + | 1722 | WP_001390306.1 | 4-hydroxyphenylalkanoate adenylyltransferase | VF |
| GC226_RS19920 (4104103) | 4104103..4105017 | + | 915 | WP_001077177.1 | NAD-dependent epimerase/dehydratase family protein | - |
| GC226_RS19925 (4105049) | 4105049..4105297 | + | 249 | WP_000248097.1 | acyl carrier protein | - |
| GC226_RS19930 (4105297) | 4105297..4106469 | + | 1173 | WP_000524972.1 | 8-amino-7-oxononanoate synthase | VF |
| GC226_RS19935 (4106504) | 4106504..4107583 | - | 1080 | WP_001298753.1 | LPS export ABC transporter permease LptG | - |
| GC226_RS19940 (4107580) | 4107580..4108650 | - | 1071 | WP_000779644.1 | LPS export ABC transporter permease LptF | - |
| GC226_RS19945 (4108681) | 4108681..4109241 | - | 561 | WP_001315848.1 | YtfJ family protein | - |
| GC226_RS19950 (4109253) | 4109253..4110077 | - | 825 | WP_000984977.1 | hypothetical protein | - |
| GC226_RS19955 (4110077) | 4110077..4111456 | - | 1380 | WP_000896911.1 | lipopolysaccharide biosynthesis protein | - |
| GC226_RS19960 (4111502) | 4111502..4112260 | - | 759 | WP_000339532.1 | hypothetical protein | - |
| GC226_RS19965 (4112292) | 4112292..4113005 | - | 714 | WP_001076237.1 | dTMP kinase | - |
| GC226_RS19970 (4113179) | 4113179..4113871 | + | 693 | WP_001190773.1 | dTMP kinase | - |
| GC226_RS19975 (4113920) | 4113920..4115419 | - | 1500 | WP_000933279.1 | inorganic phosphate transporter PitB | - |
| GC226_RS19980 (4115711) | 4115711..4117570 | - | 1860 | WP_001297309.1 | bifunctional glutathionylspermidine amidase/synthase | - |
| GC226_RS19985 (4117775) | 4117775..4118641 | + | 867 | WP_001298746.1 | glutathione-dependent disulfide-bond oxidoreductase | - |
| GC226_RS19990 (4118941) | 4118941..4119921 | + | 981 | WP_000399648.1 | IS110 family transposase IS621 | Transposase |
| GC226_RS19995 (4120043) | 4120043..4120291 | - | 249 | WP_000334896.1 | hydrogenase maturation factor HybG | - |
| GC226_RS20000 (4120304) | 4120304..4120645 | - | 342 | WP_000544952.1 | hydrogenase maturation nickel metallochaperone HypA | - |
| GC226_RS20005 (4120638) | 4120638..4121126 | - | 489 | WP_000134014.1 | hydrogenase-2 assembly chaperone | - |
| GC226_RS20010 (4121119) | 4121119..4121613 | - | 495 | WP_001221953.1 | HyaD/HybD family hydrogenase maturation endopeptidase | - |
| GC226_RS20015 (4121613) | 4121613..4123316 | - | 1704 | WP_000083065.1 | hydrogenase 2 large subunit | - |
| GC226_RS20020 (4123313) | 4123313..4124491 | - | 1179 | WP_000017703.1 | Ni/Fe-hydrogenase cytochrome b subunit | - |
| GC226_RS20025 (4124481) | 4124481..4125467 | - | 987 | WP_001081870.1 | hydrogenase 2 operon protein HybA | - |
| GC226_RS20030 (4125470) | 4125470..4126588 | - | 1119 | WP_000145410.1 | hydrogenase 2 small subunit | - |
| GC226_RS20035 (4126777) | 4126777..4127064 | - | 288 | WP_001059136.1 | DUF2623 family protein YghW | - |
| GC226_RS20040 (4127183) | 4127183..4128070 | - | 888 | WP_001297303.1 | YghX family hydrolase | - |
| GC226_RS20045 (4128227) | 4128227..4129267 | + | 1041 | WP_000262154.1 | L-glyceraldehyde 3-phosphate reductase | - |
| GC226_RS20050 (4129307) | 4129307..4129801 | - | 495 | WP_000439331.1 | TIGR00645 family protein | - |
| GC226_RS20055 (4129992) | 4129992..4130876 | + | 885 | WP_000018758.1 | putative oxidoreductase YghA | VF |
| GC226_RS20060 (4131148) | 4131148..4131573 | - | 426 | WP_001240712.1 | TonB system transport protein ExbD | - |
| GC226_RS20065 (4131580) | 4131580..4132314 | - | 735 | WP_000527844.1 | tol-pal system-associated acyl-CoA thioesterase | - |
| GC226_RS20070 (4132566) | 4132566..4133753 | + | 1188 | WP_001369830.1 | cystathionine beta-lyase | - |
| GC226_RS20075 (4133893) | 4133893..4134553 | + | 661 | Protein_3905 | DedA family protein | - |
| GC226_RS20080 (4134593) | 4134593..4135492 | - | 900 | WP_001298382.1 | DNA-binding transcriptional regulator YqhC | - |
| GC226_RS20085 (4135686) | 4135686..4136849 | + | 1164 | WP_001058807.1 | alcohol dehydrogenase | - |
| GC226_RS20090 (4136954) | 4136954..4137781 | + | 828 | WP_000013149.1 | 2,5-didehydrogluconate reductase DkgA | - |
| GC226_RS20095 (4137981) | 4137981..4138907 | + | 927 | WP_000691598.1 | YbjP/YqhG family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|