MGE detailed information

MGE type: Conjugative plasmid        MGE length: 141339 bp
Accession: NZ_CP043349        Location: 1..141339         Organism: Klebsiella pneumoniae strain WCHKP020097       Replicon: plasmid pKPC2_020097


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAY71_RS25595 (CAY71_25830) 1..1020 + 1020 WP_020314728.1 plasmid replication initiator RepA -
CAY71_RS25600 (CAY71_25835) 2334..3032 + 699 WP_020804881.1 NYN domain-containing protein -
CAY71_RS25605 (CAY71_25840) 3327..4058 + 732 WP_020804880.1 HNH endonuclease -
CAY71_RS25610 (CAY71_25845) 4096..4374 + 279 WP_020314648.1 hypothetical protein -
CAY71_RS25615 (CAY71_25850) 4692..5303 + 612 WP_020804876.1 DUF2913 family protein -
CAY71_RS25620 (CAY71_25855) 5300..6253 - 954 WP_020314639.1 Recombination-promoting nuclease RpnA VF
CAY71_RS25625 (CAY71_25860) 6374..6640 - 267 WP_022644719.1 hypothetical protein -
CAY71_RS25630 (CAY71_25865) 6660..7280 - 621 WP_020314642.1 Tn3 family transposase TnpR_TnEc1 Transposase
CAY71_RS25635 (CAY71_25870) 7659..9092 + 1434 WP_075606933.1 DNA cytosine methyltransferase -
CAY71_RS25640 (CAY71_25875) 9127..10341 - 1215 WP_148237948.1 type II restriction endonuclease -
CAY71_RS25645 (CAY71_25880) 10649..13402 + 2754 WP_075606932.1 ABC transporter -
CAY71_RS25650 (CAY71_25885) 13508..14104 - 597 WP_032635043.1 Tn3 family transposase TnpR_ISYps3 Transposase
CAY71_RS25655 (CAY71_25890) 14644..15162 + 519 WP_022644913.1 hypothetical protein -
CAY71_RS25660 (CAY71_25895) 15508..16155 + 648 WP_022644912.1 AAA family ATPase -
CAY71_RS25665 (CAY71_25900) 16146..16421 + 276 WP_032072061.1 hypothetical protein -
CAY71_RS25670 (CAY71_25905) 16614..16814 - 201 WP_022644911.1 hypothetical protein -
CAY71_RS25675 (CAY71_25910) 16916..17677 - 762 Protein_17 translesion error-prone DNA polymerase V subunit UmuC -
CAY71_RS25680 (CAY71_25920) 17744..18448 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CAY71_RS25685 (CAY71_25925) 18525..20966 - 2442 Protein_19 Tn3 family transposase TnpA_Tn3 Transposase
CAY71_RS25690 (CAY71_25930) 21129..21299 + 171 Protein_20 Tn3 family transposase TnpR_Tn3 Transposase
CAY71_RS25695 (CAY71_25935) 21360..22064 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CAY71_RS25700 (CAY71_25945) 23085..23321 - 237 WP_142295024.1 hypothetical protein -
CAY71_RS25705 (CAY71_25950) 23327..24031 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CAY71_RS25710 (CAY71_25955) 24087..24485 + 399 Protein_24 Tn3 family transposase TnpR_ISThsp9 Transposase
CAY71_RS25715 (CAY71_25960) 24532..25182 + 651 WP_015065500.1 SOS response-associated peptidase -
CAY71_RS25720 (CAY71_25965) 25479..26474 + 996 WP_019725651.1 hypothetical protein -
CAY71_RS25725 (CAY71_25970) 26547..26870 + 324 WP_019725650.1 hypothetical protein -
CAY71_RS25730 27304..27498 + 195 WP_019725033.1 hypothetical protein -
CAY71_RS25735 (CAY71_25980) 27542..27772 - 231 WP_019725034.1 hypothetical protein -
CAY71_RS25740 (CAY71_25985) 27786..27989 - 204 WP_019725040.1 HHA domain-containing protein -
CAY71_RS25745 (CAY71_25990) 28023..28391 - 369 WP_015065502.1 hypothetical protein -
CAY71_RS25750 (CAY71_25995) 28435..28929 - 495 WP_009310053.1 hypothetical protein -
CAY71_RS25755 (CAY71_26000) 28960..29532 - 573 WP_015065504.1 hypothetical protein -
CAY71_RS25760 (CAY71_26005) 29529..29777 - 249 WP_019725036.1 hypothetical protein -
CAY71_RS25765 (CAY71_26015) 30344..30688 + 345 WP_009309911.1 hypothetical protein -
CAY71_RS25770 (CAY71_26020) 30796..31431 - 636 WP_009309912.1 type II CAAX endopeptidase family protein -
CAY71_RS25775 (CAY71_26025) 31431..33539 - 2109 WP_032427226.1 peptidase domain-containing ABC transporter -
CAY71_RS25780 (CAY71_26030) 33529..34806 - 1278 WP_009309915.1 HlyD family secretion protein -
CAY71_RS25785 (CAY71_26035) 35468..36346 + 879 WP_064182004.1 restriction endonuclease -
CAY71_RS25790 (CAY71_26040) 36387..36803 - 417 WP_032425563.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
CAY71_RS25795 (CAY71_26045) 36800..37030 - 231 WP_001261276.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
CAY71_RS25800 (CAY71_26055) 37618..38562 + 945 WP_011977810.1 hypothetical protein -
CAY71_RS25805 (CAY71_26060) 38599..38991 + 393 WP_011977811.1 hypothetical protein -
CAY71_RS25810 (CAY71_26065) 39049..39570 + 522 WP_013214008.1 hypothetical protein -
CAY71_RS25815 (CAY71_26070) 39616..39819 + 204 WP_011977813.1 hypothetical protein -
CAY71_RS25820 (CAY71_26075) 39849..40853 + 1005 WP_011977814.1 hypothetical protein -
CAY71_RS25825 (CAY71_26080) 41037..41816 + 780 WP_013214009.1 site-specific integrase -
CAY71_RS25830 (CAY71_26085) 41862..42119 - 258 WP_013214010.1 hypothetical protein -
CAY71_RS25835 42248..42361 - 114 WP_014343462.1 hypothetical protein -
CAY71_RS25840 (CAY71_26090) 42897..43763 + 867 WP_004118283.1 replication initiation protein -
CAY71_RS25845 (CAY71_26100) 44873..46078 + 1206 WP_011977818.1 AAA family ATPase -
CAY71_RS25850 (CAY71_26105) 46078..47052 + 975 WP_011977819.1 ParB family protein -
CAY71_RS25855 (CAY71_26110) 47134..48405 - 1272 WP_013214011.1 Y-family DNA polymerase -
CAY71_RS25860 (CAY71_26115) 48405..48836 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
CAY71_RS25865 (CAY71_26120) 49070..50041 + 972 WP_004152353.1 plasmid segregation protein ParM -
CAY71_RS25870 (CAY71_26125) 50044..50715 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
CAY71_RS25875 (CAY71_26130) 50778..51008 + 231 WP_001568040.1 hypothetical protein -
CAY71_RS25880 51204..51373 + 170 Protein_58 hypothetical protein -
CAY71_RS25885 (CAY71_26135) 51445..52146 + 702 WP_004152355.1 DNA methylase -
CAY71_RS25890 (CAY71_26140) 52146..52367 + 222 WP_001568042.1 hypothetical protein -
CAY71_RS25895 (CAY71_26145) 52377..52796 + 420 WP_001568043.1 DUF1380 domain-containing protein -
CAY71_RS25900 (CAY71_26150) 52850..53617 + 768 WP_025714480.1 hypothetical protein -
CAY71_RS25905 (CAY71_26155) 54298..54726 + 429 WP_001568045.1 antirestriction protein -
CAY71_RS25910 (CAY71_26160) 54770..55276 + 507 WP_013214014.1 antirestriction protein ArdA -
CAY71_RS25915 (CAY71_26165) 55319..55510 + 192 WP_001568047.1 hypothetical protein -
CAY71_RS25920 (CAY71_26170) 55698..55952 + 255 WP_011977779.1 DNA polymerase III subunit theta -
CAY71_RS25925 (CAY71_26175) 55987..56307 + 321 WP_001568049.1 hypothetical protein -
CAY71_RS25930 (CAY71_26190) 56987..57214 + 228 WP_001568050.1 hypothetical protein -
CAY71_RS25935 (CAY71_26195) 57306..57536 + 231 WP_001568051.1 hypothetical protein -
CAY71_RS25940 (CAY71_26200) 57588..58943 + 1356 WP_243500793.1 DUF3560 domain-containing protein -
CAY71_RS25945 (CAY71_26205) 58991..59554 + 564 WP_014343514.1 methyltransferase -
CAY71_RS25950 (CAY71_26225) 60387..60929 + 543 WP_014343512.1 single-stranded DNA-binding protein -
CAY71_RS25955 (CAY71_26230) 60978..61226 + 249 WP_009310026.1 DUF905 domain-containing protein -
CAY71_RS25960 (CAY71_26235) 61296..63353 + 2058 WP_069335038.1 ParB/RepB/Spo0J family partition protein -
CAY71_RS25965 (CAY71_26240) 63398..63829 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
CAY71_RS25970 (CAY71_26245) 63826..64554 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
CAY71_RS25975 (CAY71_26250) 64551..64877 + 327 WP_013023807.1 hypothetical protein -
CAY71_RS25980 (CAY71_26255) 64933..65307 + 375 WP_001568060.1 hypothetical protein -
CAY71_RS25985 65477..65629 + 153 WP_004150508.1 DUF5431 family protein -
CAY71_RS25990 (CAY71_26265) 65574..65693 + 120 WP_159376494.1 type I toxin-antitoxin system Hok family toxin -
CAY71_RS25995 (CAY71_26275) 66387..66659 + 273 WP_040245921.1 hypothetical protein -
CAY71_RS26000 (CAY71_26280) 66656..67006 + 351 WP_040245917.1 hypothetical protein -
CAY71_RS26005 (CAY71_26285) 67021..67338 + 318 WP_015065519.1 hypothetical protein -
CAY71_RS26010 (CAY71_26295) 68179..68535 + 357 WP_019706019.1 hypothetical protein -
CAY71_RS26015 (CAY71_26300) 68596..68808 + 213 WP_019706020.1 hypothetical protein -
CAY71_RS26020 (CAY71_26305) 68819..69043 + 225 WP_014343499.1 hypothetical protein -
CAY71_RS26025 (CAY71_26310) 69124..69444 + 321 WP_015065521.1 type II toxin-antitoxin system RelE/ParE family toxin -
CAY71_RS26030 (CAY71_26315) 69434..69712 + 279 WP_020801586.1 helix-turn-helix transcriptional regulator -
CAY71_RS26035 (CAY71_26320) 69713..70114 + 402 WP_015065522.1 helix-turn-helix domain-containing protein -
CAY71_RS26040 (CAY71_26335) 70943..71764 + 822 WP_032441618.1 DUF932 domain-containing protein -
CAY71_RS26045 (CAY71_26340) 71797..72126 + 330 WP_087498041.1 DUF5983 family protein -
CAY71_RS26050 (CAY71_26345) 72159..72644 - 486 WP_001568108.1 hypothetical protein VF
CAY71_RS26055 (CAY71_26350) 73035..73451 + 417 WP_072145360.1 conjugal transfer relaxosome DNA-binding protein TraM -
CAY71_RS26060 (CAY71_26355) 73651..74370 + 720 WP_015065526.1 hypothetical protein -
CAY71_RS26065 (CAY71_26360) 74503..74706 + 204 WP_171486139.1 TraY domain-containing protein -
CAY71_RS26070 (CAY71_26365) 74771..75139 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
CAY71_RS26075 (CAY71_26370) 75153..75458 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
CAY71_RS26080 (CAY71_26375) 75478..76044 + 567 WP_004144423.1 type IV conjugative transfer system protein TraE -
CAY71_RS26085 (CAY71_26380) 76031..76771 + 741 WP_015065528.1 type-F conjugative transfer system secretin TraK -
CAY71_RS26090 (CAY71_26385) 76771..78195 + 1425 WP_004194260.1 F-type conjugal transfer pilus assembly protein TraB -
CAY71_RS26095 (CAY71_26390) 78309..78893 + 585 WP_015065529.1 type IV conjugative transfer system lipoprotein TraV -
CAY71_RS26100 (CAY71_26395) 79025..79435 + 411 WP_032329942.1 hypothetical protein -
CAY71_RS26105 (CAY71_26400) 79541..79759 + 219 WP_004152501.1 hypothetical protein -
CAY71_RS26110 (CAY71_26405) 79760..80071 + 312 WP_004152502.1 hypothetical protein -
CAY71_RS26115 (CAY71_26410) 80138..80542 + 405 WP_004152503.1 hypothetical protein -
CAY71_RS26120 80734..80976 + 243 WP_004158946.1 hypothetical protein -
CAY71_RS26125 (CAY71_26420) 80984..81382 + 399 WP_011977783.1 hypothetical protein -
CAY71_RS26130 (CAY71_26425) 81454..84093 + 2640 WP_004152505.1 type IV secretion system protein TraC -
CAY71_RS26135 (CAY71_26430) 84093..84482 + 390 WP_004152506.1 type-F conjugative transfer system protein TrbI -
CAY71_RS26140 (CAY71_26435) 84482..85108 + 627 WP_009309871.1 type-F conjugative transfer system protein TraW -
CAY71_RS26145 (CAY71_26440) 85150..85539 + 390 WP_015065532.1 hypothetical protein -
CAY71_RS26150 (CAY71_26445) 85536..86525 + 990 WP_011977785.1 conjugal transfer pilus assembly protein TraU -
CAY71_RS26155 (CAY71_26450) 86538..87176 + 639 WP_015065635.1 type-F conjugative transfer system pilin assembly protein TrbC -
CAY71_RS26160 (CAY71_26455) 87235..89190 + 1956 WP_030003482.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CAY71_RS26165 (CAY71_26460) 89222..89476 + 255 WP_004152674.1 conjugal transfer protein TrbE -
CAY71_RS26170 (CAY71_26465) 89454..89702 + 249 WP_004152675.1 hypothetical protein -
CAY71_RS26175 (CAY71_26470) 89715..90041 + 327 WP_004152676.1 hypothetical protein -
CAY71_RS26180 (CAY71_26475) 90062..90814 + 753 WP_020803149.1 type-F conjugative transfer system pilin assembly protein TraF -
CAY71_RS26185 (CAY71_26480) 90825..91064 + 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
CAY71_RS26190 (CAY71_26485) 91036..91608 + 573 WP_023292147.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CAY71_RS26195 (CAY71_26490) 91601..92029 + 429 WP_015065560.1 hypothetical protein -
CAY71_RS26200 (CAY71_26495) 92016..93386 + 1371 WP_004178055.1 conjugal transfer pilus assembly protein TraH -
CAY71_RS26205 (CAY71_26500) 93386..96229 + 2844 WP_015065537.1 conjugal transfer mating-pair stabilization protein TraG -
CAY71_RS26210 (CAY71_26505) 96240..96764 + 525 WP_015065538.1 hypothetical protein -
CAY71_RS26215 (CAY71_26510) 97073..97804 + 732 WP_032329926.1 conjugal transfer complement resistance protein TraT -
CAY71_RS26220 97996..98685 + 690 WP_015065540.1 hypothetical protein -
CAY71_RS26225 (CAY71_26520) 98814..101126 + 2313 WP_015065541.1 type IV conjugative transfer system coupling protein TraD -
CAY71_RS26230 (CAY71_26525) 101126..106384 + 5259 WP_062628013.1 Multifunctional conjugation protein TraI Relaxase
CAY71_RS26235 (CAY71_26530) 106464..107189 + 726 WP_015065543.1 type-F conjugative transfer system pilin acetylase TraX -
CAY71_RS26240 (CAY71_26535) 107345..107938 + 594 WP_015065544.1 fertility inhibition protein FinO -
CAY71_RS26245 (CAY71_26540) 108099..108701 + 603 WP_015060010.1 PIN domain-containing protein -
CAY71_RS26250 (CAY71_26545) 108751..109395 + 645 WP_004153014.1 hypothetical protein -
CAY71_RS26255 (CAY71_26550) 109451..110101 + 651 WP_004152382.1 DUF2726 domain-containing protein -
CAY71_RS26260 (CAY71_26555) 110098..110406 + 309 WP_004152383.1 hypothetical protein -
CAY71_RS26265 (CAY71_26560) 110510..111061 + 552 WP_087497911.1 Phospholipase D VF
CAY71_RS26270 (CAY71_26565) 111197..111466 + 270 WP_022631531.1 replication regulatory protein RepA -
CAY71_RS26275 (CAY71_26570) 111678..111755 + 78 WP_014386216.1 RepA leader peptide Tap -
CAY71_RS26280 (CAY71_26575) 111748..112299 + 552 WP_022631532.1 plasmid replication initiator RepA -
CAY71_RS26285 (CAY71_26580) 112292..113191 + 900 WP_087497909.1 plasmid replication initiator RepA -
CAY71_RS26290 (CAY71_26585) 113228..113932 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CAY71_RS26295 (CAY71_26590) 114085..115518 + 1434 WP_001288432.1 DNA cytosine methyltransferase -
CAY71_RS26300 (CAY71_26595) 115552..116766 - 1215 WP_004098817.1 type II site-specific deoxyribonuclease -
CAY71_RS26305 (CAY71_26600) 116958..117722 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
CAY71_RS26310 117840..117905 - 66 Protein_144 hypothetical protein Relaxase
CAY71_RS26315 118015..118131 - 117 Protein_145 hypothetical protein Relaxase
CAY71_RS26320 (CAY71_26615) 118352..118825 - 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
CAY71_RS26325 (CAY71_26620) 118981..119994 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
CAY71_RS26330 120387..120476 + 90 Protein_148 Tn3 family transposase TnpR_ISXc4 Transposase
CAY71_RS26335 (CAY71_26630) 120540..121244 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CAY71_RS26340 (CAY71_26635) 121294..122025 + 732 Protein_150 putative oxidoreductase YghA VF
CAY71_RS26345 (CAY71_26640) 122117..122761 - 645 WP_014386481.1 Pentapeptide repeat protein ARG
CAY71_RS26350 (CAY71_26645) 122855..123256 - 402 Protein_152 Psp operon transcriptional activator VF
CAY71_RS26355 (CAY71_26650) 123332..125134 - 1803 Protein_153 Tn3 family transposase TnpA_IS3000 Transposase
CAY71_RS26360 (CAY71_26655) 125169..127340 - 2172 Protein_154 Tn3 family transposase TnpA_Tn5403 Transposase
CAY71_RS26365 (CAY71_26660) 127416..128120 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CAY71_RS26370 (CAY71_26665) 128172..128570 + 399 Protein_156 Tn3 family transposase TnpR_Tn3 Transposase
CAY71_RS26375 (CAY71_26670) 128693..129673 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
CAY71_RS26380 (CAY71_26675) 129796..130398 + 603 WP_087497906.1 class A beta-lactamase -
CAY71_RS26385 (CAY71_26680) 130493..131374 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
CAY71_RS26390 (CAY71_26685) 131624..132505 - 882 Protein_160 IS1182 family transposase ISKpn6 Transposase
CAY71_RS26395 (CAY71_26690) 132609..132905 - 297 WP_013213987.1 transcriptional regulator -
CAY71_RS26400 132951..133106 - 156 WP_013213988.1 hypothetical protein -
CAY71_RS26405 (CAY71_26695) 133234..133659 - 426 WP_013213989.1 antirestriction protein -
CAY71_RS26410 (CAY71_26700) 133770..134048 - 279 WP_013213990.1 hypothetical protein -
CAY71_RS26415 (CAY71_26705) 134582..135199 - 618 Protein_165 replication protein -
CAY71_RS26420 (CAY71_26710) 135591..136151 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
CAY71_RS26425 (CAY71_26715) 136155..139121 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
CAY71_RS26430 (CAY71_26720) 139154..139687 + 534 Protein_168 DUF2726 domain-containing protein -
CAY71_RS26435 (CAY71_26725) 139684..139992 + 309 WP_004098858.1 hypothetical protein -
CAY71_RS26440 (CAY71_26730) 140087..140644 + 558 WP_020315133.1 Phospholipase D VF
CAY71_RS26445 (CAY71_26735) 140777..141031 + 255 WP_004098862.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance