MGE detailed information
MGE type: Conjugative plasmid MGE length: 116435 bp
Accession: NZ_CP043282 Location: 1..116435 Organism: Escherichia coli strain WCHEC025157 Replicon: plasmid p1_025157
Accession: NZ_CP043282 Location: 1..116435 Organism: Escherichia coli strain WCHEC025157 Replicon: plasmid p1_025157
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FYK41_RS23820 (1) | 1..858 | + | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| FYK41_RS23825 (1559) | 1559..1699 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| FYK41_RS23830 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| FYK41_RS23835 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FYK41_RS23840 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FYK41_RS23845 (3271) | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| FYK41_RS23850 (6263) | 6263..6868 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| FYK41_RS23855 (6892) | 6892..7641 | - | 750 | Protein_7 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FYK41_RS23860 (7645) | 7645..8037 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| FYK41_RS23865 (8175) | 8175..9059 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| FYK41_RS23870 (9091) | 9091..10290 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| FYK41_RS23875 (10396) | 10396..11046 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| FYK41_RS23880 (11078) | 11078..11320 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| FYK41_RS23885 (11362) | 11362..12876 | - | 1515 | Protein_13 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FYK41_RS23890 (12942) | 12942..13646 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FYK41_RS23895 (13699) | 13699..13947 | - | 249 | Protein_15 | DUF3330 domain-containing protein | - |
| FYK41_RS23900 (14150) | 14150..15163 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| FYK41_RS23905 (15321) | 15321..15794 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| FYK41_RS23910 (15925) | 15925..16713 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| FYK41_RS23915 (16919) | 16919..17266 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| FYK41_RS23920 (17260) | 17260..18099 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| FYK41_RS23925 (18227) | 18227..18430 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| FYK41_RS23930 (18586) | 18586..19791 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| FYK41_RS23935 (19802) | 19802..20107 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| FYK41_RS23940 (20151) | 20151..20216 | + | 66 | Protein_24 | EAL domain-containing protein | - |
| FYK41_RS23945 (20334) | 20334..21098 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| FYK41_RS23950 (21591) | 21591..22175 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| FYK41_RS23955 (22175) | 22175..23413 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| FYK41_RS23960 (23410) | 23410..24315 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| FYK41_RS23965 (24437) | 24437..25141 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FYK41_RS23970 (25202) | 25202..27613 | + | 2412 | Protein_30 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| FYK41_RS23975 (27647) | 27647..27751 | + | 105 | Protein_31 | IS5/IS1182 family transposase | - |
| FYK41_RS23980 (27901) | 27901..28533 | - | 633 | Protein_32 | histidine-type phosphatase | - |
| FYK41_RS23985 (28655) | 28655..29140 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| FYK41_RS23990 (29165) | 29165..29650 | - | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| FYK41_RS23995 (29637) | 29637..30332 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| FYK41_RS24000 (30337) | 30337..31467 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
| FYK41_RS24005 (31457) | 31457..32740 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| FYK41_RS24010 (32743) | 32743..34122 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| FYK41_RS24015 (34226) | 34226..34753 | - | 528 | WP_000178050.1 | iron transporter | - |
| FYK41_RS24020 (34794) | 34794..36680 | - | 1887 | WP_141035010.1 | FTR1 family protein | - |
| FYK41_RS24025 (37027) | 37027..37788 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| FYK41_RS24030 (38025) | 38025..38531 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| FYK41_RS24035 (38521) | 38521..38691 | - | 171 | Protein_43 | DsbA family protein | - |
| FYK41_RS24040 (38829) | 38829..38942 | - | 114 | Protein_44 | IS6 family transposase | - |
| FYK41_RS24045 (39142) | 39142..39839 | + | 698 | WP_223350503.1 | IS1 family transposase IS1X2 | Transposase |
| FYK41_RS24050 (39989) | 39989..40675 | + | 687 | Protein_46 | IS1 family transposase IS1S | Transposase |
| FYK41_RS24055 (40929) | 40929..41951 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| FYK41_RS24060 (41936) | 41936..43501 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| FYK41_RS24065 (43576) | 43576..43992 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FYK41_RS24070 (43989) | 43989..44219 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| FYK41_RS24075 (44779) | 44779..44997 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| FYK41_RS24080 (44999) | 44999..45304 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| FYK41_RS24085 (45305) | 45305..46111 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| FYK41_RS24090 (46833) | 46833..47588 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| FYK41_RS24095 (48176) | 48176..49342 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| FYK41_RS24100 (49342) | 49342..50313 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FYK41_RS24105 (51051) | 51051..51953 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| FYK41_RS24110 (51950) | 51950..52261 | + | 312 | WP_012615291.1 | hypothetical protein | - |
| FYK41_RS24115 (52338) | 52338..53021 | + | 684 | WP_032181561.1 | DNA methylase | - |
| FYK41_RS24120 (53022) | 53022..53243 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| FYK41_RS24125 (53173) | 53173..53691 | + | 519 | WP_223349485.1 | DUF1380 family protein | - |
| FYK41_RS24130 (53736) | 53736..54506 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| FYK41_RS24135 (54920) | 54920..55345 | + | 426 | WP_001546490.1 | antirestriction protein | - |
| FYK41_RS24140 (55392) | 55392..55814 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| FYK41_RS24145 (55811) | 55811..56002 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| FYK41_RS24150 (56274) | 56274..56522 | - | 249 | WP_071781657.1 | hypothetical protein | - |
| FYK41_RS24155 (57039) | 57039..57269 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| FYK41_RS24160 (57321) | 57321..58682 | + | 1362 | WP_039023242.1 | DUF3560 domain-containing protein | - |
| FYK41_RS24165 (58730) | 58730..59293 | + | 564 | WP_029702196.1 | class I SAM-dependent methyltransferase | - |
| FYK41_RS24170 (59445) | 59445..59723 | + | 279 | WP_071811814.1 | hypothetical protein | - |
| FYK41_RS24175 (60654) | 60654..61223 | - | 570 | WP_089634947.1 | hypothetical protein | - |
| FYK41_RS24185 (62527) | 62527..63285 | + | 759 | Protein_73 | site-specific integrase | - |
| FYK41_RS24190 (63443) | 63443..64453 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| FYK41_RS24195 (64549) | 64549..66675 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| FYK41_RS24200 (66738) | 66738..68015 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| FYK41_RS24205 (68015) | 68015..69445 | + | 1431 | WP_000813680.1 | glycoside hydrolase family 32 protein | - |
| FYK41_RS24210 (69640) | 69640..71034 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
| FYK41_RS24215 (71280) | 71280..71384 | - | 105 | Protein_79 | thiosulfate reductase cytochrome B subunit | - |
| FYK41_RS24220 (71441) | 71441..72134 | + | 694 | Protein_80 | IS1 family transposase IS1A | Transposase |
| FYK41_RS24225 (72261) | 72261..72773 | + | 513 | WP_223350513.1 | potassium channel family protein | - |
| FYK41_RS24230 (72858) | 72858..73109 | + | 252 | Protein_82 | iron-containing alcohol dehydrogenase | - |
| FYK41_RS24235 (73398) | 73398..73715 | - | 318 | Protein_83 | IS110 family transposase IS1618 | Transposase |
| FYK41_RS24240 (73870) | 73870..73975 | + | 106 | Protein_84 | plasmid SOS inhibition protein A | - |
| - (73944) | 73944..74142 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (73944) | 73944..74142 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (73944) | 73944..74142 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (73944) | 73944..74142 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| FYK41_RS24245 (74149) | 74149..74298 | + | 150 | Protein_85 | DUF5431 family protein | - |
| FYK41_RS24250 (74240) | 74240..74365 | + | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FYK41_RS24255 (74666) | 74666..74963 | - | 298 | Protein_87 | hypothetical protein | - |
| FYK41_RS24260 (75033) | 75033..75239 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| FYK41_RS24265 (75264) | 75264..75551 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| FYK41_RS24270 (75670) | 75670..76491 | + | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
| FYK41_RS24275 (76787) | 76787..77359 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
| FYK41_RS24280 (77729) | 77729..78112 | + | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| FYK41_RS24285 (78303) | 78303..78950 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| FYK41_RS24290 (79086) | 79086..79301 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| FYK41_RS24295 (79344) | 79344..79709 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| FYK41_RS24300 (79724) | 79724..80035 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| FYK41_RS24305 (80057) | 80057..80623 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| FYK41_RS24310 (80610) | 80610..81338 | + | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| FYK41_RS24315 (81338) | 81338..82765 | + | 1428 | WP_001553836.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| FYK41_RS24320 (82755) | 82755..83345 | + | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| FYK41_RS24325 (83332) | 83332..83652 | + | 321 | Protein_101 | conjugal transfer protein TrbD | - |
| FYK41_RS24330 (83645) | 83645..83896 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| FYK41_RS24335 (83893) | 83893..84408 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FYK41_RS24340 (84543) | 84543..84764 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| FYK41_RS24345 (84924) | 84924..87551 | + | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| FYK41_RS24350 (87548) | 87548..87934 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| FYK41_RS24355 (87931) | 87931..88563 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| FYK41_RS24360 (88560) | 88560..89552 | + | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| FYK41_RS24365 (89561) | 89561..90199 | + | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FYK41_RS24370 (90196) | 90196..92004 | + | 1809 | WP_039023153.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| FYK41_RS24375 (92031) | 92031..92288 | + | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| FYK41_RS24380 (92281) | 92281..93024 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FYK41_RS24385 (93040) | 93040..93387 | + | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| FYK41_RS24390 (93506) | 93506..93790 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FYK41_RS24395 (93777) | 93777..94322 | + | 546 | WP_016236310.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FYK41_RS24400 (94252) | 94252..94614 | + | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| FYK41_RS24405 (94614) | 94614..95987 | + | 1374 | WP_039023150.1 | conjugal transfer pilus assembly protein TraH | - |
| FYK41_RS24410 (95984) | 95984..98803 | + | 2820 | WP_039023149.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| FYK41_RS24415 (98822) | 98822..99319 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| FYK41_RS24420 (99351) | 99351..100082 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| FYK41_RS24425 (100335) | 100335..102506 | + | 2172 | WP_121350052.1 | type IV conjugative transfer system coupling protein TraD | - |
| FYK41_RS24430 (102515) | 102515..102913 | - | 399 | WP_039023147.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FYK41_RS24435 (102913) | 102913..103140 | - | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| FYK41_RS24440 (103222) | 103222..108492 | + | 5271 | WP_039023145.1 | Multifunctional conjugation protein TraI | Relaxase |
| FYK41_RS24445 (108768) | 108768..110309 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| FYK41_RS24450 (110324) | 110324..111070 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| FYK41_RS24455 (111098) | 111098..111844 | + | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| FYK41_RS24460 (111899) | 111899..112459 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| FYK41_RS24465 (112590) | 112590..112799 | + | 210 | WP_039023209.1 | hypothetical protein | - |
| FYK41_RS24470 (113211) | 113211..113837 | + | 627 | WP_029702149.1 | NYN domain-containing protein | - |
| FYK41_RS24475 (113989) | 113989..114558 | + | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| FYK41_RS24480 (114771) | 114771..115199 | + | 429 | WP_029702151.1 | hypothetical protein | - |
| - (115338) | 115338..115399 | - | 62 | NuclAT_1 | - | - |
| - (115338) | 115338..115399 | - | 62 | NuclAT_1 | - | - |
| - (115338) | 115338..115399 | - | 62 | NuclAT_1 | - | - |
| - (115338) | 115338..115399 | - | 62 | NuclAT_1 | - | - |
| FYK41_RS24485 (115443) | 115443..115592 | + | 150 | WP_001367749.1 | Hok/Gef family protein | - |
| FYK41_RS24490 (115876) | 115876..116133 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| FYK41_RS24495 (116238) | 116238..116423 | + | 186 | WP_077818652.1 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|