MGE detailed information
MGE type: Mobilizable plasmid MGE length: 134972 bp
Accession: NZ_CP041375 Location: 1..134972 Organism: Klebsiella pneumoniae strain KP58 Replicon: plasmid pKP58-2
Accession: NZ_CP041375 Location: 1..134972 Organism: Klebsiella pneumoniae strain KP58 Replicon: plasmid pKP58-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FM021_RS28515 () | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| FM021_RS28525 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| FM021_RS28530 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FM021_RS28535 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FM021_RS28540 () | 3383..3798 | + | 416 | Protein_5 | IS1 family transposase | - |
| FM021_RS28545 () | 3834..4379 | - | 546 | Protein_6 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FM021_RS28550 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FM021_RS28555 () | 5219..5410 | + | 192 | Protein_8 | transposase | - |
| FM021_RS28560 () | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| FM021_RS28565 () | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| FM021_RS28570 () | 7595..8692 | + | 1098 | Protein_11 | TonB-dependent receptor | - |
| FM021_RS28575 () | 8760..9209 | - | 450 | Protein_12 | PAS domain-containing protein | - |
| FM021_RS28580 () | 9289..9993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FM021_RS28585 () | 10058..10648 | + | 591 | Protein_14 | IS91 family transposase ISSbo1 | Transposase |
| FM021_RS28595 () | 11104..11808 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FM021_RS28600 () | 11859..12476 | - | 618 | Protein_16 | IS91 family transposase ISSbo1 | Transposase |
| FM021_RS28605 () | 12486..12674 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| FM021_RS28610 () | 12766..13302 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FM021_RS28615 () | 13485..14345 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| FM021_RS28620 () | 14515..15270 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| FM021_RS28625 () | 15351..15632 | - | 282 | WP_015059004.1 | sodium/hydrogen exchanger | - |
| FM021_RS28630 () | 15720..16424 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FM021_RS30775 () | 16490..16555 | + | 66 | Protein_23 | IS1 family transposase | - |
| FM021_RS28650 () | 18004..18238 | + | 235 | Protein_24 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FM021_RS28655 () | 18366..18647 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| FM021_RS28660 () | 18770..19120 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| FM021_RS28665 () | 19123..20085 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| FM021_RS28670 () | 20232..20525 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| FM021_RS28680 () | 20602..21285 | + | 684 | WP_000085883.1 | DNA methylase | - |
| FM021_RS28685 () | 21286..21507 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| FM021_RS28690 () | 21521..21955 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| FM021_RS30780 () | 22006..22782 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| FM021_RS28705 () | 23200..23625 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| FM021_RS28710 () | 23672..24094 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| FM021_RS28715 () | 24091..24282 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| FM021_RS28720 () | 24596..26263 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| FM021_RS28730 () | 27663..27893 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| FM021_RS28735 () | 27945..29306 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| FM021_RS28740 () | 29353..29916 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| FM021_RS28765 () | 30759..31286 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| FM021_RS28770 () | 31344..31577 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| FM021_RS28775 () | 31638..33661 | + | 2024 | Protein_42 | ParB/RepB/Spo0J family partition protein | - |
| FM021_RS28780 () | 33730..34164 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| FM021_RS28785 () | 34161..34880 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| FM021_RS28790 () | 35160..35318 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FM021_RS30785 () | 35556..35933 | - | 378 | Protein_46 | hypothetical protein | - |
| FM021_RS28810 () | 36233..36529 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| FM021_RS28815 () | 36640..37461 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| FM021_RS28820 () | 37758..38405 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| FM021_RS28825 () | 38682..39065 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| FM021_RS28835 () | 39346..40050 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FM021_RS28840 () | 40104..40427 | - | 324 | Protein_52 | class II aldolase/adducin family protein | - |
| FM021_RS28845 () | 40420..41672 | - | 1253 | Protein_53 | four-carbon acid sugar kinase family protein | - |
| FM021_RS28850 () | 41684..42586 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| FM021_RS28860 () | 42848..43609 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| FM021_RS28865 () | 43630..44490 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| FM021_RS28875 () | 44627..44695 | + | 69 | Protein_57 | IS6 family transposase | - |
| FM021_RS28880 () | 44731..47697 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FM021_RS28885 () | 47701..48261 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| FM021_RS28890 () | 48653..49270 | + | 618 | Protein_60 | replication protein | - |
| FM021_RS28895 () | 49804..50082 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| FM021_RS28900 () | 50193..50618 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| FM021_RS30790 () | 50746..50901 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| FM021_RS28905 () | 50947..51243 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| FM021_RS28910 () | 51347..52228 | + | 882 | Protein_65 | IS1182 family transposase ISKpn6 | Transposase |
| FM021_RS28915 () | 52478..53359 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| FM021_RS28920 () | 53635..54615 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| FM021_RS28925 () | 54738..55199 | - | 462 | Protein_68 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FM021_RS28935 () | 55251..55955 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FM021_RS28940 () | 56020..57192 | - | 1173 | Protein_70 | transposase | - |
| FM021_RS28950 () | 57267..57935 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| FM021_RS28955 () | 57971..58207 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| FM021_RS28960 () | 58204..58566 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| FM021_RS28965 () | 58584..60278 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| FM021_RS28970 () | 60330..60752 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| FM021_RS28975 () | 60788..61063 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| FM021_RS28980 () | 61077..61427 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| FM021_RS28985 () | 61499..61933 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| FM021_RS28990 () | 62012..63016 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| FM021_RS28995 () | 63544..64944 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| FM021_RS29000 () | 64941..65621 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| FM021_RS29005 () | 65827..66807 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| FM021_RS29010 () | 66876..67805 | - | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| FM021_RS29015 () | 67810..68190 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| FM021_RS29020 () | 68230..69120 | - | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| FM021_RS29025 () | 69126..70943 | - | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| FM021_RS29030 () | 71177..71644 | + | 468 | WP_048336866.1 | hypothetical protein | - |
| FM021_RS29035 () | 71911..72648 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| FM021_RS29040 () | 72682..72879 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| FM021_RS29045 () | 72920..75367 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| FM021_RS29050 () | 75494..75934 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| FM021_RS29055 () | 76021..79167 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| FM021_RS29060 () | 79178..80470 | - | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| FM021_RS29065 () | 80584..80946 | - | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| FM021_RS29070 () | 80975..82360 | - | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| FM021_RS29075 () | 82550..83230 | + | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| FM021_RS29080 () | 83223..84698 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| FM021_RS29085 () | 84949..85380 | + | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| FM021_RS29090 () | 85524..85874 | + | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| FM021_RS29095 () | 86261..87169 | - | 909 | WP_023302803.1 | HNH endonuclease | - |
| FM021_RS29100 () | 87806..88780 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| FM021_RS29105 () | 88959..89204 | + | 246 | Protein_102 | hypothetical protein | - |
| FM021_RS29110 () | 89365..90309 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| FM021_RS29115 () | 90346..90738 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| FM021_RS29120 () | 90796..91317 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| FM021_RS29125 () | 91363..91566 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| FM021_RS29130 () | 91596..92600 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| FM021_RS29135 () | 92784..93563 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| FM021_RS29140 () | 93609..93866 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| FM021_RS30795 () | 93995..94108 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| FM021_RS29145 () | 94644..95510 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| FM021_RS29155 () | 96620..97825 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| FM021_RS29160 () | 97825..98799 | + | 975 | WP_011977819.1 | ParB/RepB/Spo0J family partition protein | - |
| FM021_RS29165 () | 98881..100152 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| FM021_RS29170 () | 100152..100583 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| FM021_RS29180 () | 100990..102477 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| FM021_RS29185 () | 102726..103697 | + | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| FM021_RS29190 () | 103700..104371 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| FM021_RS29195 () | 104434..104664 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| FM021_RS29200 () | 105101..105802 | + | 702 | WP_001568041.1 | DNA methylase | - |
| FM021_RS29205 () | 105802..106023 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| FM021_RS29210 () | 106033..106452 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| FM021_RS29215 () | 106506..107273 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| FM021_RS29220 () | 107954..108382 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| FM021_RS29225 () | 108425..108931 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| FM021_RS29230 () | 108974..109165 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| FM021_RS29235 () | 109353..109607 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| FM021_RS29240 () | 109642..109962 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| FM021_RS29255 () | 110642..110869 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| FM021_RS29260 () | 110961..111191 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| FM021_RS29265 () | 111243..112598 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| FM021_RS29270 () | 112646..113209 | + | 564 | WP_014343514.1 | methyltransferase | - |
| FM021_RS29290 () | 114042..114584 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| FM021_RS29295 () | 114633..114881 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| FM021_RS29300 () | 114951..117008 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| FM021_RS29305 () | 117053..117484 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| FM021_RS29310 () | 117481..118209 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| FM021_RS29315 () | 118206..118532 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| FM021_RS29320 () | 118588..118962 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| FM021_RS29330 () | 119190..119348 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| FM021_RS29340 () | 120041..120313 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| FM021_RS29345 () | 120310..120660 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| FM021_RS29350 () | 120675..120992 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| FM021_RS29360 () | 121833..122189 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| FM021_RS29365 () | 122250..122462 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| FM021_RS29370 () | 122473..122697 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| FM021_RS29375 () | 122778..123098 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FM021_RS29380 () | 123088..123366 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| FM021_RS29405 () | 124303..125124 | + | 822 | WP_004152492.1 | DUF945 domain-containing protein | - |
| FM021_RS29410 () | 125157..125486 | + | 330 | WP_013214015.1 | hypothetical protein | - |
| FM021_RS29415 () | 125519..126004 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| FM021_RS29420 () | 126395..126811 | + | 417 | WP_014343494.1 | relaxosome protein TraM | - |
| FM021_RS29425 () | 127011..127748 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| FM021_RS29430 () | 127863..128069 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| FM021_RS29435 () | 128131..128499 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| FM021_RS29440 () | 128513..128818 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| FM021_RS29445 () | 128838..129203 | + | 366 | Protein_157 | type IV conjugative transfer system protein TraE | - |
| FM021_RS29455 () | 129258..129602 | - | 345 | Protein_158 | IS6 family transposase IS26 | Transposase |
| FM021_RS29465 () | 129654..130358 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FM021_RS29470 () | 130422..130583 | + | 162 | Protein_160 | DNA helicase | - |
| FM021_RS29475 () | 130603..131349 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| FM021_RS29480 () | 131404..131964 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| FM021_RS29485 () | 132096..132296 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| FM021_RS29490 () | 132682..133281 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| FM021_RS29495 () | 133445..133675 | + | 231 | WP_001736714.1 | hypothetical protein | - |
| - () | 133876..133935 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 133876..133935 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 133876..133935 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 133876..133935 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| FM021_RS29505 () | 133980..134129 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FM021_RS29510 () | 134413..134661 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|