MGE detailed information
MGE type: Conjugative plasmid MGE length: 150137 bp
Accession: NZ_CP041301 Location: 1..150137 Organism: Escherichia coli strain MSHS 472 Replicon: plasmid pCys-6
Accession: NZ_CP041301 Location: 1..150137 Organism: Escherichia coli strain MSHS 472 Replicon: plasmid pCys-6
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FK543_RS00010 () | 216..1643 | - | 1428 | WP_000146672.1 | conjugal transfer protein TraB | - |
| FK543_RS00015 () | 1643..2347 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| FK543_RS00020 () | 2358..2924 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| FK543_RS00025 () | 2946..3257 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| FK543_RS00030 () | 3262..3624 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| FK543_RS00035 () | 3657..4052 | - | 396 | WP_053320748.1 | conjugal transfer relaxosome protein TraY | - |
| FK543_RS00040 () | 4151..4840 | - | 690 | WP_000283380.1 | conjugal transfer transcriptional regulator TraJ | - |
| FK543_RS00045 () | 5027..5410 | - | 384 | WP_053320747.1 | relaxosome protein TraM | - |
| FK543_RS00050 () | 5730..6332 | + | 603 | WP_000243709.1 | transglycosylase SLT domain-containing protein | - |
| FK543_RS00055 () | 6629..7450 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| FK543_RS00060 () | 7570..7857 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| FK543_RS24375 () | 7882..8088 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| FK543_RS00080 () | 8779..8937 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 8981..9205 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 8981..9205 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 8981..9205 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 8981..9205 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| FK543_RS24250 () | 9017..9205 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| FK543_RS00085 () | 9217..9936 | - | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| FK543_RS00090 () | 9933..10367 | - | 435 | WP_000845934.1 | conjugation system SOS inhibitor PsiB | - |
| FK543_RS00095 () | 10422..12380 | - | 1959 | WP_023148339.1 | ParB/RepB/Spo0J family partition protein | - |
| FK543_RS00100 () | 12446..12679 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| FK543_RS00105 () | 12742..13281 | - | 540 | WP_000290791.1 | single-stranded DNA-binding protein | - |
| FK543_RS24255 () | 13479..13739 | - | 261 | WP_071600428.1 | hypothetical protein | - |
| FK543_RS00120 () | 13891..14454 | - | 564 | WP_001299724.1 | class I SAM-dependent methyltransferase | - |
| FK543_RS00125 () | 14502..15863 | - | 1362 | WP_000170715.1 | DUF3560 domain-containing protein | - |
| FK543_RS00130 () | 15915..16145 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| FK543_RS24570 () | 16659..17175 | + | 517 | Protein_24 | hypothetical protein | - |
| FK543_RS24380 () | 17145..17336 | - | 192 | WP_065800505.1 | hypothetical protein | - |
| FK543_RS00145 () | 17333..17734 | - | 402 | WP_114139213.1 | DUF1380 family protein | - |
| FK543_RS00150 () | 17796..18098 | - | 303 | WP_072256028.1 | antirestriction protein | - |
| FK543_RS00160 () | 18622..19386 | + | 765 | Protein_28 | IS110-like element ISEc32 family transposase | - |
| FK543_RS00165 () | 19400..20097 | - | 698 | Protein_29 | IS1 family transposase | - |
| FK543_RS00170 () | 20151..20483 | - | 333 | Protein_30 | hypothetical protein | - |
| FK543_RS24575 () | 20552..20890 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| FK543_RS00185 () | 21700..22671 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FK543_RS00190 () | 22671..23837 | - | 1167 | WP_001238646.1 | plasmid-partitioning protein SopA | - |
| FK543_RS00195 () | 24137..24833 | - | 697 | Protein_34 | IS1 family transposase | - |
| FK543_RS00200 () | 24989..26491 | - | 1503 | WP_072657541.1 | hypothetical protein | - |
| FK543_RS00205 () | 27109..27558 | - | 450 | WP_000238252.1 | hypothetical protein | - |
| FK543_RS00210 () | 27676..28155 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| FK543_RS00220 () | 28595..28822 | + | 228 | Protein_38 | malate dehydrogenase | - |
| FK543_RS00225 () | 28819..28950 | - | 132 | Protein_39 | phosphopyruvate hydratase | - |
| FK543_RS00230 () | 28948..29205 | + | 258 | Protein_40 | Tn3 family transposase | - |
| FK543_RS00235 () | 29439..30296 | - | 858 | WP_000968139.1 | iron/manganese ABC transporter permease subunit SitD | - |
| FK543_RS00240 () | 30293..31150 | - | 858 | WP_000992806.1 | iron/manganese ABC transporter permease subunit SitC | - |
| FK543_RS00245 () | 31119..31973 | - | 855 | WP_141874663.1 | iron/manganese ABC transporter ATP-binding protein SitB | - |
| FK543_RS00250 () | 31973..32887 | - | 915 | WP_000949004.1 | iron/manganese ABC transporter substrate-binding protein SitA | - |
| FK543_RS00260 () | 33243..33940 | + | 698 | Protein_45 | IS1 family transposase | - |
| FK543_RS00265 () | 34120..34633 | - | 514 | Protein_46 | DUF4113 domain-containing protein | - |
| FK543_RS24385 () | 34694..34798 | - | 105 | Protein_47 | AAA family ATPase | - |
| FK543_RS00275 () | 34800..35123 | - | 324 | Protein_48 | helix-turn-helix domain-containing protein | - |
| FK543_RS00285 () | 35869..36846 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| FK543_RS00290 () | 37131..37871 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| FK543_RS00295 () | 37992..38180 | - | 189 | WP_072652414.1 | serine/threonine protein kinase | - |
| FK543_RS00300 () | 38554..39441 | - | 888 | WP_137521412.1 | antimicrobial resistance protein Mig-14 | - |
| FK543_RS00305 () | 39524..40633 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| FK543_RS00315 () | 41066..42019 | - | 954 | WP_000280980.1 | omptin family outer membrane protease | - |
| FK543_RS00330 () | 43290..43448 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| FK543_RS00335 () | 43632..43934 | + | 303 | Protein_56 | transposase | - |
| FK543_RS00340 () | 43990..44687 | + | 698 | Protein_57 | IS1 family transposase | - |
| FK543_RS24390 () | 44681..44962 | - | 282 | WP_072834405.1 | hypothetical protein | - |
| FK543_RS00350 () | 45103..46928 | - | 1826 | Protein_59 | AAA family ATPase | - |
| FK543_RS00360 () | 47137..48105 | - | 969 | WP_031942297.1 | IS5-like element IS903B family transposase | - |
| FK543_RS00365 () | 48729..48878 | - | 150 | Protein_61 | IS3 family transposase | - |
| FK543_RS00370 () | 49056..50249 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| FK543_RS00380 () | 51472..52708 | - | 1237 | Protein_63 | IS3 family transposase | - |
| FK543_RS00385 () | 53335..53628 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| FK543_RS00390 () | 53686..53885 | - | 200 | Protein_65 | lysis system i-spanin subunit Rz | - |
| FK543_RS00400 () | 54439..55537 | + | 1099 | Protein_66 | transposase | - |
| FK543_RS00410 () | 56773..57888 | + | 1116 | WP_001318220.1 | salmochelin biosynthesis C-glycosyltransferase IroB | - |
| FK543_RS00415 () | 58028..61687 | + | 3660 | WP_001111199.1 | salmochelin/enterobactin export ABC transporter IroC | - |
| FK543_RS00420 () | 61791..63020 | + | 1230 | WP_001552738.1 | catecholate siderophore esterase IroD | - |
| FK543_RS00425 () | 63105..64061 | + | 957 | WP_000271276.1 | catecholate siderophore esterase IroE | - |
| FK543_RS00430 () | 64106..66283 | - | 2178 | WP_072657522.1 | siderophore salmochelin receptor IroN | - |
| FK543_RS00435 () | 66441..67138 | - | 698 | Protein_72 | IS1 family transposase | - |
| FK543_RS00440 () | 67190..67264 | - | 75 | Protein_73 | colicin | - |
| FK543_RS00445 () | 67242..67478 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| FK543_RS00450 () | 67942..68223 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| FK543_RS00455 () | 68396..68563 | + | 168 | Protein_76 | colicin-B | - |
| FK543_RS00460 () | 68581..69108 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| FK543_RS00470 () | 69352..70167 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| FK543_RS00475 () | 70217..70570 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| FK543_RS00480 () | 70748..71539 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| FK543_RS00490 () | 72009..72224 | - | 216 | Protein_81 | hypothetical protein | - |
| FK543_RS00495 () | 72268..72618 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| FK543_RS00505 () | 73190..73450 | + | 261 | WP_000343102.1 | hypothetical protein | - |
| FK543_RS00510 () | 73447..74037 | + | 591 | WP_000194555.1 | hypothetical protein | - |
| FK543_RS00515 () | 74055..74402 | - | 348 | WP_000142424.1 | hypothetical protein | - |
| FK543_RS00520 () | 74521..74868 | + | 348 | WP_000762580.1 | hypothetical protein | - |
| FK543_RS00525 () | 74886..76766 | - | 1881 | WP_001283356.1 | colicin | - |
| FK543_RS24395 () | 77045..77710 | - | 666 | WP_000448921.1 | hypothetical protein | - |
| FK543_RS24400 () | 77875..78390 | - | 516 | WP_174234259.1 | hypothetical protein | - |
| FK543_RS00540 () | 78744..79346 | + | 603 | WP_000517689.1 | hypothetical protein | - |
| FK543_RS00545 () | 79402..79896 | + | 495 | WP_001442119.1 | hypothetical protein | - |
| FK543_RS24405 () | 79896..80162 | + | 267 | WP_000627831.1 | hypothetical protein | - |
| FK543_RS00560 () | 80639..81055 | - | 417 | WP_031610367.1 | hypothetical protein | - |
| FK543_RS00565 () | 81064..84030 | - | 2967 | WP_001138064.1 | Tn3-like element TnAs3 family transposase | - |
| FK543_RS00570 () | 84033..84593 | - | 561 | WP_000147567.1 | recombinase family protein | - |
| FK543_RS00575 () | 84719..85069 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| FK543_RS00585 () | 85272..86285 | - | 1014 | WP_000845039.1 | class 1 integron integrase IntI1 | - |
| FK543_RS00590 () | 86430..86927 | + | 498 | WP_001083725.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | - |
| FK543_RS00595 () | 87039..87329 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| FK543_RS00600 () | 87335..88126 | + | 792 | WP_001206356.1 | ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2 | - |
| FK543_RS00605 () | 88290..88637 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| FK543_RS00610 () | 88631..89470 | + | 840 | WP_000259031.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | - |
| FK543_RS00620 () | 89598..89801 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| FK543_RS00625 () | 89957..91162 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| FK543_RS00630 () | 91173..91478 | + | 306 | WP_000130000.1 | PadR family transcriptional regulator | - |
| FK543_RS24295 () | 91522..91587 | + | 66 | Protein_106 | EAL domain-containing protein | - |
| FK543_RS00640 () | 91705..92469 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| FK543_RS00655 () | 92962..93546 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| FK543_RS00660 () | 93546..94783 | - | 1238 | Protein_109 | MFS transporter | - |
| FK543_RS00665 () | 94780..95685 | - | 906 | WP_100620385.1 | Mph(A) family macrolide 2'-phosphotransferase | - |
| FK543_RS00675 () | 95807..96511 | - | 705 | WP_001067834.1 | IS6-like element IS26 family transposase | - |
| FK543_RS00680 () | 96576..97826 | - | 1251 | Protein_112 | DDE-type integrase/transposase/recombinase | - |
| FK543_RS00690 () | 97901..98569 | - | 669 | WP_001300294.1 | EAL domain-containing protein | - |
| FK543_RS00695 () | 98605..98841 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| FK543_RS00700 () | 98838..99200 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| FK543_RS00705 () | 99218..100912 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| FK543_RS00710 () | 100964..101386 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| FK543_RS00715 () | 101422..101697 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| FK543_RS00720 () | 101711..102061 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| FK543_RS00725 () | 102133..102567 | + | 435 | WP_000429836.1 | Hg(II)-responsive transcriptional regulator | - |
| FK543_RS00740 () | 103569..103811 | + | 243 | WP_000844627.1 | transposase | - |
| FK543_RS00745 () | 103843..104493 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| FK543_RS00750 () | 104599..105798 | + | 1200 | WP_000804064.1 | tetracycline efflux MFS transporter Tet(A) | - |
| FK543_RS00755 () | 105830..106713 | - | 884 | Protein_124 | EamA family transporter | - |
| FK543_RS00760 () | 106851..107258 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| FK543_RS00765 () | 107247..107996 | + | 750 | Protein_126 | Tn3 family transposase | - |
| FK543_RS00770 () | 108020..108625 | - | 606 | WP_000509965.1 | recombinase family protein | - |
| FK543_RS00775 () | 108720..111578 | + | 2859 | WP_141874665.1 | Tn3-like element Tn5403 family transposase | - |
| FK543_RS00780 () | 111753..112154 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FK543_RS00785 () | 112087..112344 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FK543_RS00790 () | 112437..113090 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| FK543_RS00805 () | 114031..114888 | - | 858 | WP_065800511.1 | incFII family plasmid replication initiator RepA | - |
| FK543_RS00810 () | 114881..114955 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| FK543_RS00815 () | 115190..115450 | - | 261 | WP_000078108.1 | replication regulatory protein RepA | - |
| FK543_RS00820 () | 116392..119247 | - | 2856 | WP_053320759.1 | chromosome segregation protein SMC | - |
| FK543_RS00825 () | 119312..121345 | - | 2034 | WP_000887497.1 | N-6 DNA methylase | - |
| FK543_RS00830 () | 121391..123940 | - | 2550 | WP_053320758.1 | DEAD/DEAH box helicase family protein | - |
| FK543_RS00840 () | 124225..124437 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| FK543_RS00845 () | 124573..125133 | - | 561 | WP_024184455.1 | fertility inhibition protein FinO | - |
| FK543_RS00850 () | 125188..125870 | - | 683 | Protein_140 | conjugal transfer pilus acetylase TraX | - |
| FK543_RS24580 () | 125949..131211 | - | 5263 | Protein_141 | conjugative transfer relaxase/helicase TraI | - |
| FK543_RS00875 () | 131211..133412 | - | 2202 | Protein_142 | type IV conjugative transfer system coupling protein TraD | - |
| FK543_RS00880 () | 133666..133941 | - | 276 | Protein_143 | hypothetical protein | - |
| FK543_RS24585 () | 133868..134372 | - | 505 | Protein_144 | conjugal transfer protein TraT | - |
| FK543_RS24445 () | 134421..134566 | - | 146 | Protein_145 | conjugal transfer protein TraS | - |
| FK543_RS24450 () | 134583..134795 | - | 213 | WP_174234264.1 | hypothetical protein | - |
| FK543_RS24455 () | 134743..134916 | - | 174 | WP_174234265.1 | hypothetical protein | - |
| FK543_RS00895 () | 134997..137755 | - | 2759 | Protein_148 | conjugal transfer mating pair stabilization protein TraG | - |
| FK543_RS00900 () | 137752..139126 | - | 1375 | Protein_149 | conjugal transfer protein TraH | - |
| FK543_RS24460 () | 139126..139489 | - | 364 | Protein_150 | P-type conjugative transfer protein TrbJ | - |
| FK543_RS00910 () | 139419..139948 | - | 530 | Protein_151 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FK543_RS00915 () | 139952..140232 | - | 281 | Protein_152 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FK543_RS00920 () | 140349..141091 | - | 743 | Protein_153 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FK543_RS00925 () | 141084..141344 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| FK543_RS00930 () | 141370..141997 | - | 628 | Protein_155 | conjugal transfer protein TraN | - |
| FK543_RS24465 () | 142041..143175 | - | 1135 | Protein_156 | conjugal transfer protein TraN | - |
| FK543_RS00940 () | 143172..143750 | - | 579 | Protein_157 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FK543_RS00945 () | 143815..144807 | - | 993 | WP_053320745.1 | conjugal transfer pilus assembly protein TraU | - |
| FK543_RS00950 () | 144804..145435 | - | 632 | Protein_159 | type-F conjugative transfer system protein TraW | - |
| FK543_RS00955 () | 145432..145817 | - | 386 | Protein_160 | type-F conjugative transfer system protein TrbI | - |
| FK543_RS00960 () | 145814..148441 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| FK543_RS00965 () | 148601..148822 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| FK543_RS00970 () | 148957..149472 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FK543_RS00975 () | 149469..149837 | - | 369 | WP_071787938.1 | conjugal transfer protein TrbD | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|