MGE detailed information
MGE type: Mobilizable plasmid MGE length: 102347 bp
Accession: NZ_CP041286 Location: 1..102347 Organism: Escherichia coli strain 54 Replicon: plasmid p54-tetX
Accession: NZ_CP041286 Location: 1..102347 Organism: Escherichia coli strain 54 Replicon: plasmid p54-tetX
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FK536_RS22445 () | 1..1011 | + | 1011 | WP_000200070.1 | RepB family plasmid replication initiator protein | - |
| FK536_RS22450 () | 1205..2173 | + | 969 | WP_077816224.1 | IS5 family transposase IS903B | Transposase |
| FK536_RS22455 () | 2340..2756 | - | 417 | WP_033548869.1 | hypothetical protein | - |
| FK536_RS22460 () | 3341..3676 | + | 336 | WP_001039462.1 | hypothetical protein | - |
| FK536_RS22465 () | 3685..3876 | + | 192 | WP_001515192.1 | hypothetical protein | - |
| FK536_RS22470 () | 3887..4470 | - | 584 | Protein_5 | IS1 family transposase IS1X4 | Transposase |
| FK536_RS22475 () | 5004..5759 | + | 756 | WP_000807690.1 | replication initiation protein RepE | - |
| FK536_RS22480 () | 6028..6373 | + | 346 | Protein_7 | IS1 family transposase IS1X4 | Transposase |
| FK536_RS22490 () | 6884..7024 | + | 141 | WP_160784086.1 | hypothetical protein | - |
| FK536_RS22495 () | 7119..7823 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FK536_RS22500 () | 7909..9345 | - | 1437 | WP_000105383.1 | glutathione synthase | - |
| FK536_RS22505 () | 9612..10316 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FK536_RS22510 () | 10370..10627 | + | 258 | Protein_12 | ISKra4 family transposase ISKpn19 | Transposase |
| FK536_RS22515 () | 11018..11674 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| FK536_RS22520 () | 11835..12539 | + | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| FK536_RS22525 () | 12593..13126 | + | 534 | Protein_15 | IS6 family transposase IS15DI | Transposase |
| FK536_RS22530 () | 13180..13647 | + | 468 | Protein_16 | conjugal transfer protein | - |
| FK536_RS22535 () | 13892..14008 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| FK536_RS22540 () | 14024..15943 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| FK536_RS22545 () | 16062..16229 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| FK536_RS22550 () | 16237..16467 | - | 231 | WP_136655701.1 | hypothetical protein | - |
| FK536_RS22555 () | 16469..17104 | + | 636 | Protein_21 | transposase | - |
| FK536_RS22560 () | 17525..18019 | + | 495 | WP_077141251.1 | IS91 family transposase ISAzo26 | Transposase |
| FK536_RS22565 () | 18130..18990 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| FK536_RS22570 () | 19173..19730 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FK536_RS22575 () | 19894..22899 | + | 3006 | WP_001531602.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FK536_RS22580 () | 22935..23696 | - | 762 | Protein_26 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FK536_RS22585 () | 23685..24092 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| FK536_RS22590 () | 24230..25114 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| FK536_RS22595 () | 25146..26345 | - | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| FK536_RS22600 () | 26451..27101 | + | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| FK536_RS22605 () | 27133..27375 | - | 243 | WP_000844627.1 | transposase | - |
| FK536_RS22610 () | 27433..27933 | - | 501 | Protein_32 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FK536_RS22615 () | 27999..28703 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FK536_RS22620 () | 28757..29410 | - | 654 | Protein_34 | IS91 family transposase ISPps1 | Transposase |
| FK536_RS22625 () | 29522..29827 | - | 306 | WP_001255015.1 | LysR family transcriptional regulator | - |
| FK536_RS22630 () | 29855..31069 | - | 1215 | WP_034167813.1 | Inner membrane transport protein YdhC | ARG |
| FK536_RS23075 () | 31286..31732 | - | 447 | Protein_37 | DUF3363 domain-containing protein | - |
| FK536_RS22640 () | 32201..33565 | - | 1365 | Protein_38 | IS91 family transposase ISVsa3 | Transposase |
| FK536_RS22645 () | 33579..34034 | - | 456 | WP_136655511.1 | MarR family transcriptional regulator | - |
| FK536_RS22650 () | 34257..34886 | + | 630 | WP_136655510.1 | Chloramphenicol acetyltransferase | VF |
| FK536_RS22655 () | 34934..36547 | - | 1614 | WP_136655509.1 | ATP-binding cassette domain-containing protein | - |
| FK536_RS22665 () | 36909..38402 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| FK536_RS22670 () | 38741..39898 | - | 1158 | WP_094309310.1 | Kynurenine 3-monooxygenase | ARG |
| FK536_RS22675 () | 39888..40733 | - | 846 | WP_164538741.1 | alpha/beta fold hydrolase | - |
| FK536_RS22680 () | 41150..41287 | + | 138 | WP_164538590.1 | hypothetical protein | - |
| FK536_RS22690 () | 41515..42360 | - | 846 | Protein_46 | IS91 family transposase ISVsa3 | Transposase |
| FK536_RS22695 () | 42425..43129 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FK536_RS22700 () | 43182..43274 | - | 93 | Protein_48 | QacE family quaternary ammonium compound efflux SMR transporter | - |
| FK536_RS22705 () | 43458..43931 | - | 474 | WP_001317507.1 | Dihydrofolate reductase type 1 | ARG |
| FK536_RS22710 () | 44087..45100 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| FK536_RS22715 () | 45246..45950 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FK536_RS22720 () | 46003..46128 | + | 126 | Protein_52 | quaternary ammonium compound efflux SMR transporter QacL | - |
| FK536_RS22725 () | 46393..47028 | - | 636 | Protein_53 | transposase | - |
| FK536_RS22730 () | 47030..47305 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| FK536_RS22735 () | 47308..48099 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| FK536_RS22740 () | 48568..48813 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| FK536_RS22745 () | 48851..49714 | - | 864 | WP_054377175.1 | SDR family oxidoreductase | - |
| FK536_RS22750 () | 49860..51089 | - | 1230 | WP_032492336.1 | Putative bacilysin exporter BacE | ARG |
| FK536_RS22755 () | 51217..51921 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FK536_RS22760 () | 51973..52176 | - | 204 | Protein_60 | mercuric resistance transcriptional repressor protein MerD | - |
| FK536_RS22765 () | 52194..53888 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| FK536_RS22770 () | 53940..54362 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| FK536_RS22775 () | 54398..54673 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| FK536_RS22780 () | 54687..55037 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| FK536_RS22785 () | 55109..55543 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| FK536_RS22790 () | 55576..56511 | - | 936 | Protein_66 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FK536_RS22795 () | 56541..57245 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FK536_RS22800 () | 57618..58315 | + | 698 | Protein_68 | IS1 family transposase | - |
| FK536_RS22805 () | 58340..58774 | - | 435 | WP_053273090.1 | hypothetical protein | - |
| FK536_RS22810 () | 58755..58838 | + | 84 | WP_000565612.1 | hypothetical protein | - |
| FK536_RS22815 () | 58993..59637 | - | 645 | WP_000203396.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| FK536_RS22820 () | 60018..60680 | + | 663 | WP_000516402.1 | peptidyl-arginine deiminase | - |
| FK536_RS22825 () | 60778..61059 | + | 282 | WP_001185482.1 | hypothetical protein | - |
| FK536_RS22830 () | 61084..62061 | + | 978 | WP_024245156.1 | hypothetical protein | - |
| FK536_RS22835 () | 62058..62483 | - | 426 | WP_000202942.1 | hypothetical protein | - |
| FK536_RS22840 () | 62551..62997 | - | 447 | Protein_76 | hypothetical protein | - |
| FK536_RS22845 () | 63037..63873 | - | 837 | WP_001050931.1 | replication initiation protein | - |
| FK536_RS22850 () | 65107..65358 | + | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
| FK536_RS22855 () | 65348..65629 | + | 282 | WP_000220560.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| FK536_RS22860 () | 65704..66401 | + | 698 | Protein_80 | IS1 family transposase | - |
| FK536_RS22865 () | 66547..66804 | + | 258 | WP_105278499.1 | hypothetical protein | - |
| FK536_RS22870 () | 66841..67809 | - | 969 | WP_077783444.1 | IS5 family transposase IS903B | Transposase |
| FK536_RS22875 () | 67844..68119 | + | 276 | Protein_83 | peptidoglycan DD-metalloendopeptidase family protein | - |
| FK536_RS22880 () | 68153..68350 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| FK536_RS22885 () | 68391..70868 | - | 2478 | WP_001398208.1 | Ag(+)-translocating P-type ATPase SilP | - |
| FK536_RS22890 () | 70966..71406 | - | 441 | WP_000758229.1 | hypothetical protein | - |
| FK536_RS22895 () | 71493..74639 | - | 3147 | WP_020219104.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| FK536_RS22900 () | 74650..75942 | - | 1293 | WP_001381488.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| FK536_RS22905 () | 76056..76409 | - | 354 | WP_001246155.1 | cation efflux system protein CusF | - |
| FK536_RS22910 () | 76437..77822 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| FK536_RS22915 () | 78012..78692 | + | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| FK536_RS22920 () | 78685..80160 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| FK536_RS22925 () | 80411..80842 | + | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| FK536_RS22930 () | 80986..81336 | + | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| FK536_RS22935 () | 81724..82632 | - | 909 | Protein_95 | HNH endonuclease | - |
| FK536_RS22940 () | 83104..84332 | + | 1229 | WP_089541817.1 | IS3 family transposase IS2 | Transposase |
| FK536_RS22945 () | 84605..85579 | + | 975 | WP_001148756.1 | sensor domain-containing diguanylate cyclase | - |
| FK536_RS22950 () | 86509..87180 | + | 672 | WP_000796235.1 | hypothetical protein | - |
| FK536_RS22955 () | 87200..87988 | + | 789 | WP_022631000.1 | site-specific integrase | - |
| FK536_RS22960 () | 88282..89178 | - | 897 | Protein_100 | IS3 family transposase ISEhe3 | Transposase |
| FK536_RS22965 () | 89188..90339 | - | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| FK536_RS22970 () | 90421..90570 | - | 150 | Protein_102 | IS3 family transposase ISEhe3 | Transposase |
| FK536_RS22975 () | 90717..90998 | + | 282 | WP_000639434.1 | hypothetical protein | - |
| FK536_RS22980 () | 91099..91797 | - | 699 | Protein_104 | IS1 family transposase | - |
| FK536_RS22985 () | 91907..93232 | + | 1326 | WP_021512928.1 | pyridine nucleotide-disulfide oxidoreductase | - |
| FK536_RS22990 () | 93439..94136 | + | 698 | Protein_106 | IS1 family transposase | - |
| FK536_RS22995 () | 94166..94513 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| FK536_RS23000 () | 94562..96099 | + | 1538 | Protein_108 | IS66 family transposase ISEc22 | Transposase |
| FK536_RS23005 () | 97413..98111 | + | 699 | Protein_109 | IS1 family transposase | - |
| FK536_RS23010 () | 98130..98975 | + | 846 | Protein_110 | IS3 family transposase IS911 | Transposase |
| FK536_RS23015 () | 99470..100441 | - | 972 | WP_000817038.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FK536_RS23020 () | 100441..101607 | - | 1167 | WP_000523812.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|