MGE detailed information
MGE type: Conjugative plasmid MGE length: 139734 bp
Accession: NZ_CP040658 Location: 1..139734 Organism: Klebsiella pneumoniae strain 2019010306 Replicon: plasmid p.SXKP01030601
Accession: NZ_CP040658 Location: 1..139734 Organism: Klebsiella pneumoniae strain 2019010306 Replicon: plasmid p.SXKP01030601
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E3148_RS25860 (1) | 1..1011 | + | 1011 | WP_000200070.1 | RepB family plasmid replication initiator protein | - |
| E3148_RS25865 (1728) | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| E3148_RS25875 (4287) | 4287..4631 | + | 345 | Protein_3 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| E3148_RS25880 (4647) | 4647..5483 | + | 837 | WP_004178087.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| E3148_RS25885 (6466) | 6466..7743 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| E3148_RS25890 (7806) | 7806..9803 | - | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| E3148_RS25905 (12141) | 12141..12625 | + | 485 | Protein_9 | IS1 family transposase IS1X2 | Transposase |
| E3148_RS25910 (12641) | 12641..13183 | + | 543 | Protein_10 | ISL3 family transposase ISKpn25 | Transposase |
| E3148_RS25915 (13479) | 13479..13910 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| E3148_RS25920 (14161) | 14161..15636 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| E3148_RS25925 (15629) | 15629..16309 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| E3148_RS25930 (16499) | 16499..17884 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| E3148_RS25935 (17913) | 17913..18266 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| E3148_RS25940 (18380) | 18380..19672 | + | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| E3148_RS25945 (19683) | 19683..22829 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| E3148_RS25950 (22916) | 22916..23356 | + | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| E3148_RS25955 (23483) | 23483..25930 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| E3148_RS25960 (25971) | 25971..26168 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| E3148_RS25965 (26202) | 26202..26939 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| E3148_RS25970 (27228) | 27228..27677 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| E3148_RS25975 (27911) | 27911..29728 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| E3148_RS25980 (29734) | 29734..30624 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| E3148_RS25985 (30664) | 30664..31044 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| E3148_RS25990 (31049) | 31049..31978 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| E3148_RS25995 (32033) | 32033..32713 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| E3148_RS26000 (32710) | 32710..34110 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| E3148_RS26005 (34327) | 34327..34761 | + | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| E3148_RS26010 (34993) | 34993..35172 | - | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| E3148_RS26015 (35233) | 35233..36853 | - | 1621 | Protein_31 | ISL3 family transposase | - |
| E3148_RS26020 (36915) | 36915..37424 | + | 510 | WP_031944101.1 | aquaporin | - |
| E3148_RS26025 (37474) | 37474..37971 | - | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| E3148_RS26030 (38303) | 38303..38629 | + | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| E3148_RS26035 (38626) | 38626..39339 | + | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| E3148_RS26040 (39348) | 39348..39893 | + | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| E3148_RS26045 (39969) | 39969..40331 | + | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| E3148_RS26050 (40350) | 40350..42106 | + | 1757 | Protein_38 | arsenical pump-driving ATPase | - |
| E3148_RS26055 (42228) | 42228..42764 | + | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| E3148_RS26060 (42797) | 42797..43222 | - | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| E3148_RS26065 (43235) | 43235..44524 | - | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| E3148_RS26070 (44572) | 44572..46323 | - | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| E3148_RS26075 (46341) | 46341..46703 | - | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| E3148_RS26080 (46753) | 46753..47103 | - | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| E3148_RS26085 (47461) | 47461..47730 | + | 270 | WP_004152102.1 | hypothetical protein | - |
| E3148_RS26090 (47718) | 47718..48293 | + | 576 | WP_004152103.1 | hypothetical protein | - |
| E3148_RS26095 (48324) | 48324..48818 | + | 495 | WP_004152104.1 | DNA-binding protein | - |
| E3148_RS26100 (48862) | 48862..49230 | + | 369 | WP_004152105.1 | hypothetical protein | - |
| E3148_RS26105 (49264) | 49264..49467 | + | 204 | WP_004152106.1 | HHA domain-containing protein | - |
| E3148_RS26110 (49516) | 49516..49773 | + | 258 | WP_004152107.1 | hypothetical protein | - |
| E3148_RS26115 (49849) | 49849..50103 | + | 255 | WP_004152108.1 | hypothetical protein | - |
| E3148_RS26120 (50279) | 50279..50545 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| E3148_RS26125 (50533) | 50533..51015 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| E3148_RS26130 (51227) | 51227..52573 | + | 1347 | WP_020314316.1 | ISNCY family transposase ISLad2 | Transposase |
| E3148_RS26135 (52734) | 52734..52865 | + | 132 | WP_004218042.1 | hypothetical protein | - |
| E3148_RS26140 (53074) | 53074..54239 | - | 1166 | Protein_56 | IS3 family transposase ISKpn38 | Transposase |
| E3148_RS26145 (54416) | 54416..55378 | - | 963 | WP_004152113.1 | zinc metalloprotease HtpX | - |
| E3148_RS26150 (55365) | 55365..55853 | - | 489 | WP_004152114.1 | phosphate-starvation-inducible PsiE family protein | - |
| E3148_RS26155 (55968) | 55968..56114 | - | 147 | Protein_59 | diguanylate cyclase | - |
| E3148_RS26160 (56352) | 56352..56549 | - | 198 | WP_004152115.1 | hypothetical protein | - |
| E3148_RS26165 (56549) | 56549..59344 | - | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| E3148_RS26170 (59459) | 59459..60028 | - | 570 | WP_004152117.1 | Spore protein SP21 | VF |
| E3148_RS26175 (60063) | 60063..60344 | - | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| E3148_RS26180 (60588) | 60588..60851 | - | 264 | WP_004118208.1 | hypothetical protein | - |
| E3148_RS26185 (60866) | 60866..61129 | + | 264 | WP_004118209.1 | transposase | - |
| E3148_RS26190 (61074) | 61074..61190 | + | 117 | Protein_66 | transposase domain-containing protein | - |
| E3148_RS26195 (61375) | 61375..62072 | + | 698 | WP_223174644.1 | IS1 family transposase IS1X2 | Transposase |
| E3148_RS26200 (62331) | 62331..63311 | + | 981 | WP_014386148.1 | IS5 family transposase ISKpn26 | Transposase |
| E3148_RS26205 (63893) | 63893..64412 | - | 520 | Protein_69 | IS5 family transposase ISPst7 | Transposase |
| E3148_RS26210 (64520) | 64520..65389 | - | 870 | WP_004152692.1 | HTH-type transcriptional activator CmpR | VF |
| E3148_RS26215 (65383) | 65383..66393 | - | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| E3148_RS26220 (66402) | 66402..67229 | - | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| E3148_RS26225 (67238) | 67238..67492 | - | 255 | Protein_73 | PhnD/SsuA/transferrin family substrate-binding protein | - |
| E3148_RS26230 (67548) | 67548..68252 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E3148_RS26235 (68314) | 68314..68427 | - | 114 | Protein_75 | recombinase family protein | - |
| E3148_RS26240 (68522) | 68522..71419 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| E3148_RS26245 (71556) | 71556..71957 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| E3148_RS26250 (71890) | 71890..72147 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| E3148_RS26255 (72240) | 72240..72893 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| E3148_RS26260 (73883) | 73883..74758 | - | 876 | WP_072101968.1 | incFII family plasmid replication initiator RepA | - |
| E3148_RS26265 (75056) | 75056..75313 | - | 258 | WP_015344940.1 | replication regulatory protein RepA | - |
| E3148_RS26270 (75445) | 75445..75996 | - | 552 | WP_015344941.1 | Phospholipase D | VF |
| E3148_RS26275 (76100) | 76100..76408 | - | 309 | WP_004152383.1 | hypothetical protein | - |
| E3148_RS26280 (76405) | 76405..77055 | - | 651 | WP_014343480.1 | DUF2726 domain-containing protein | - |
| E3148_RS26285 (77111) | 77111..77755 | - | 645 | WP_004153014.1 | hypothetical protein | - |
| E3148_RS26290 (77805) | 77805..78407 | - | 603 | WP_013023836.1 | PIN domain-containing protein | - |
| E3148_RS26295 (78568) | 78568..79161 | - | 594 | WP_015344942.1 | fertility inhibition protein FinO | - |
| E3148_RS26300 (79233) | 79233..79958 | - | 726 | WP_015344943.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| E3148_RS26305 (80002) | 80002..85263 | - | 5262 | WP_064291677.1 | Multifunctional conjugation protein TraI | Relaxase |
| E3148_RS26310 (85263) | 85263..87575 | - | 2313 | WP_072101984.1 | type IV conjugative transfer system coupling protein TraD | - |
| E3148_RS26315 (87704) | 87704..88393 | - | 690 | WP_072101983.1 | hypothetical protein | - |
| E3148_RS26320 (88586) | 88586..89317 | - | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| E3148_RS26325 (89503) | 89503..90036 | - | 534 | WP_014343486.1 | conjugal transfer protein TraS | - |
| E3148_RS26330 (90039) | 90039..92888 | - | 2850 | WP_013609534.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| E3148_RS26335 (92888) | 92888..94267 | - | 1380 | WP_014343487.1 | conjugal transfer pilus assembly protein TraH | - |
| E3148_RS26340 (94245) | 94245..94688 | - | 444 | WP_014343488.1 | F-type conjugal transfer protein TrbF | - |
| E3148_RS26345 (94734) | 94734..95291 | - | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| E3148_RS26350 (95263) | 95263..95502 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| E3148_RS26355 (95513) | 95513..96265 | - | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| E3148_RS26360 (96286) | 96286..96612 | - | 327 | WP_004152676.1 | hypothetical protein | - |
| E3148_RS26365 (96625) | 96625..96873 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| E3148_RS26370 (96851) | 96851..97105 | - | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| E3148_RS26375 (97137) | 97137..99092 | - | 1956 | WP_014343489.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| E3148_RS26380 (99151) | 99151..99789 | - | 639 | WP_004193871.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| E3148_RS26385 (99802) | 99802..100791 | - | 990 | WP_013214027.1 | conjugal transfer pilus assembly protein TraU | - |
| E3148_RS26390 (100788) | 100788..101189 | - | 402 | WP_004194979.1 | hypothetical protein | - |
| E3148_RS26395 (101224) | 101224..101859 | - | 636 | WP_013214026.1 | type-F conjugative transfer system protein TraW | - |
| E3148_RS26400 (101859) | 101859..102248 | - | 390 | WP_013214025.1 | type-F conjugative transfer system protein TrbI | - |
| E3148_RS26405 (102248) | 102248..104887 | - | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| E3148_RS26410 (104959) | 104959..105357 | - | 399 | WP_023179972.1 | hypothetical protein | - |
| E3148_RS26415 (105736) | 105736..106140 | - | 405 | WP_065802628.1 | hypothetical protein | - |
| E3148_RS26420 (106207) | 106207..106518 | - | 312 | WP_159224514.1 | hypothetical protein | - |
| E3148_RS26425 (106519) | 106519..106737 | - | 219 | WP_014386199.1 | hypothetical protein | - |
| E3148_RS26430 (106761) | 106761..106985 | - | 225 | WP_286496684.1 | hypothetical protein | - |
| E3148_RS26435 (107061) | 107061..107645 | - | 585 | WP_032440547.1 | type IV conjugative transfer system lipoprotein TraV | - |
| E3148_RS26440 (107718) | 107718..109142 | - | 1425 | WP_004194260.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| E3148_RS26445 (109142) | 109142..109882 | - | 741 | WP_013023821.1 | type-F conjugative transfer system secretin TraK | - |
| E3148_RS26450 (109869) | 109869..110435 | - | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| E3148_RS26455 (110455) | 110455..110760 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| E3148_RS26460 (110774) | 110774..111142 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| E3148_RS26465 (111211) | 111211..111411 | - | 201 | WP_004194116.1 | TraY domain-containing protein | - |
| E3148_RS26470 (111497) | 111497..112198 | - | 702 | WP_004194113.1 | hypothetical protein | - |
| E3148_RS26475 (112428) | 112428..112820 | - | 393 | WP_004194114.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| E3148_RS26480 (113252) | 113252..113737 | + | 486 | WP_001568108.1 | hypothetical protein | VF |
| E3148_RS26485 (113770) | 113770..114099 | - | 330 | WP_014386191.1 | DUF5983 family protein | - |
| E3148_RS26490 (114132) | 114132..114953 | - | 822 | WP_004182076.1 | DUF932 domain-containing protein | - |
| E3148_RS26495 (115783) | 115783..116196 | - | 414 | WP_069985713.1 | helix-turn-helix domain-containing protein | - |
| E3148_RS26500 (116197) | 116197..116475 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| E3148_RS26505 (116465) | 116465..116785 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| E3148_RS26510 (116866) | 116866..117090 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| E3148_RS26515 (117101) | 117101..117313 | - | 213 | WP_019706020.1 | hypothetical protein | - |
| E3148_RS26520 (117374) | 117374..117730 | - | 357 | WP_019706019.1 | hypothetical protein | - |
| E3148_RS26525 (118362) | 118362..118712 | - | 351 | WP_023287104.1 | hypothetical protein | - |
| E3148_RS26530 (118709) | 118709..118981 | - | 273 | WP_023287105.1 | hypothetical protein | - |
| E3148_RS26535 (119675) | 119675..119833 | - | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| E3148_RS26540 (119903) | 119903..120976 | + | 1074 | WP_048270288.1 | IS481 family transposase ISKpn28 | Transposase |
| - (120976) | 120976..121100 | - | 125 | NuclAT_0 | - | - |
| - (120976) | 120976..121100 | - | 125 | NuclAT_0 | - | - |
| - (120976) | 120976..121100 | - | 125 | NuclAT_0 | - | - |
| - (120976) | 120976..121100 | - | 125 | NuclAT_0 | - | - |
| E3148_RS26545 (121160) | 121160..121534 | - | 375 | WP_023287106.1 | hypothetical protein | - |
| E3148_RS26550 (121590) | 121590..121916 | - | 327 | WP_001568059.1 | hypothetical protein | - |
| E3148_RS26555 (121913) | 121913..122641 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| E3148_RS26560 (122638) | 122638..123069 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| E3148_RS26565 (123114) | 123114..125171 | - | 2058 | WP_023287107.1 | ParB/RepB/Spo0J family partition protein | - |
| E3148_RS26570 (125241) | 125241..125489 | - | 249 | WP_009310026.1 | DUF905 domain-containing protein | - |
| E3148_RS26575 (125538) | 125538..126080 | - | 543 | WP_015065513.1 | single-stranded DNA-binding protein | - |
| E3148_RS26580 (126916) | 126916..127479 | - | 564 | WP_004152756.1 | methyltransferase | - |
| E3148_RS26585 (127527) | 127527..128882 | - | 1356 | WP_014386157.1 | DUF3560 domain-containing protein | - |
| E3148_RS26590 (128934) | 128934..129164 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| E3148_RS26595 (129256) | 129256..129483 | - | 228 | WP_004178072.1 | hypothetical protein | - |
| E3148_RS26600 (130264) | 130264..130581 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| E3148_RS26605 (130616) | 130616..130870 | - | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| E3148_RS26610 (131107) | 131107..131532 | - | 426 | WP_004118478.1 | antirestriction protein | - |
| E3148_RS26615 (132053) | 132053..132283 | - | 231 | WP_004118481.1 | hypothetical protein | - |
| E3148_RS26620 (132498) | 132498..132923 | + | 426 | WP_004182047.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| E3148_RS26625 (132923) | 132923..134194 | + | 1272 | WP_014386156.1 | Y-family DNA polymerase | - |
| E3148_RS26630 (134333) | 134333..134488 | + | 156 | WP_001776126.1 | hypothetical protein | - |
| E3148_RS26635 (134511) | 134511..135709 | - | 1199 | Protein_155 | IS200-IS605 family transposase IS609 | Transposase |
| E3148_RS26640 (136846) | 136846..137817 | - | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| E3148_RS26645 (137817) | 137817..138983 | - | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|