MGE detailed information
MGE type: Conjugative plasmid MGE length: 115257 bp
Accession: NZ_CP038182 Location: 1..115257 Organism: Escherichia coli strain Replicon: 2 HS-C plasmid p2HS-C-2
Accession: NZ_CP038182 Location: 1..115257 Organism: Escherichia coli strain Replicon: 2 HS-C plasmid p2HS-C-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4F32_RS22305 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| E4F32_RS22310 () | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| E4F32_RS22315 () | 2124..2312 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| E4F32_RS22320 () | 2686..3588 | - | 903 | WP_001312822.1 | antimicrobial resistance protein Mig-14 | - |
| E4F32_RS22325 () | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| E4F32_RS22335 () | 5199..6152 | - | 954 | WP_000280980.1 | omptin family outer membrane protease | - |
| E4F32_RS23300 () | 6256..6645 | + | 390 | WP_001332050.1 | outer membrane protease | - |
| E4F32_RS22350 () | 7425..7583 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| E4F32_RS22355 () | 7767..8069 | + | 303 | Protein_8 | transposase | - |
| E4F32_RS22360 () | 8163..8492 | + | 330 | Protein_9 | single-stranded DNA-binding protein | - |
| E4F32_RS22365 () | 8555..8788 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| E4F32_RS22370 () | 8854..9063 | + | 210 | Protein_11 | hypothetical protein | - |
| E4F32_RS23185 () | 9089..9223 | + | 135 | WP_000715153.1 | hypothetical protein | - |
| E4F32_RS22375 () | 9278..9712 | + | 435 | WP_000845934.1 | conjugation system SOS inhibitor PsiB | - |
| E4F32_RS22380 () | 9709..10428 | + | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| E4F32_RS23190 () | 10440..10628 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 10440..10664 | + | 225 | NuclAT_0 | - | - |
| - () | 10440..10664 | + | 225 | NuclAT_0 | - | - |
| - () | 10440..10664 | + | 225 | NuclAT_0 | - | - |
| - () | 10440..10664 | + | 225 | NuclAT_0 | - | - |
| - () | 10597..10662 | + | 66 | - | - | Antitoxin Detail |
| E4F32_RS22385 () | 10708..10866 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| E4F32_RS23305 () | 11161..11316 | + | 156 | WP_032072147.1 | hypothetical protein | - |
| E4F32_RS23310 () | 11557..11763 | + | 207 | WP_000547939.1 | hypothetical protein | - |
| E4F32_RS22405 () | 11788..12075 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| E4F32_RS22410 () | 12197..13018 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| E4F32_RS22415 () | 13315..13917 | - | 603 | WP_000243709.1 | transglycosylase SLT domain-containing protein | - |
| E4F32_RS22420 () | 14238..14621 | + | 384 | WP_053320747.1 | relaxosome protein TraM | - |
| E4F32_RS22425 () | 14808..15497 | + | 690 | WP_000283380.1 | conjugal transfer transcriptional regulator TraJ | - |
| E4F32_RS22430 () | 15596..15991 | + | 396 | WP_053320748.1 | conjugal transfer relaxosome protein TraY | - |
| E4F32_RS22435 () | 16024..16386 | + | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| E4F32_RS22440 () | 16391..16702 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| E4F32_RS22445 () | 16724..17290 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| E4F32_RS22450 () | 17301..18005 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| E4F32_RS23315 () | 18005..18157 | + | 153 | Protein_29 | conjugal transfer protein TraC | - |
| E4F32_RS23320 () | 18152..18298 | + | 147 | Protein_30 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| E4F32_RS22460 () | 18228..18590 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| E4F32_RS22465 () | 18590..19963 | + | 1374 | WP_065800514.1 | conjugal transfer protein TraH | - |
| E4F32_RS22470 () | 19960..22308 | + | 2349 | Protein_33 | conjugal transfer mating pair stabilization protein TraG | - |
| E4F32_RS23325 () | 22304..23188 | + | 885 | Protein_34 | type IV secretion system DNA-binding domain-containing protein | - |
| E4F32_RS22475 () | 23183..26572 | + | 3390 | Protein_35 | conjugative transfer relaxase/helicase TraI | - |
| E4F32_RS22480 () | 26592..27335 | + | 744 | WP_000205704.1 | conjugal transfer pilus acetylase TraX | - |
| E4F32_RS22485 () | 27390..27950 | + | 561 | WP_024184455.1 | fertility inhibition protein FinO | - |
| E4F32_RS22490 () | 28086..28298 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| E4F32_RS22500 () | 28584..31133 | + | 2550 | WP_053320758.1 | DEAD/DEAH box helicase family protein | - |
| E4F32_RS22505 () | 31179..33212 | + | 2034 | WP_000887497.1 | N-6 DNA methylase | - |
| E4F32_RS22510 () | 33277..36132 | + | 2856 | WP_053320759.1 | chromosome segregation protein SMC | - |
| E4F32_RS22515 () | 37074..37334 | + | 261 | WP_000078108.1 | replication regulatory protein RepA | - |
| E4F32_RS22520 () | 37569..37643 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| E4F32_RS22525 () | 37636..38493 | + | 858 | WP_065800511.1 | incFII family plasmid replication initiator RepA | - |
| E4F32_RS22535 () | 39432..40085 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| E4F32_RS22540 () | 40178..40435 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| E4F32_RS22545 () | 40368..40769 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| E4F32_RS22550 () | 41054..42364 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| E4F32_RS22555 () | 42393..42491 | + | 99 | Protein_49 | IS1 family transposase | - |
| E4F32_RS22560 () | 42641..43501 | - | 861 | WP_000027057.1 | class A broad-spectrum beta-lactamase TEM-1 | - |
| E4F32_RS22565 () | 43804..44508 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| E4F32_RS22570 () | 44564..44803 | + | 240 | Protein_52 | transposase | - |
| E4F32_RS22575 () | 44812..45672 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| E4F32_RS22580 () | 45704..46903 | - | 1200 | WP_000804064.1 | tetracycline efflux MFS transporter Tet(A) | - |
| E4F32_RS22585 () | 47009..47635 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| E4F32_RS22590 () | 47667..47915 | - | 249 | WP_134778721.1 | relaxase | - |
| E4F32_RS22595 () | 47969..48805 | - | 837 | WP_000480972.1 | aminoglycoside O-phosphotransferase APH(6)-Id | - |
| E4F32_RS22600 () | 48805..49608 | - | 804 | WP_001082319.1 | aminoglycoside O-phosphotransferase APH(3'')-Ib | - |
| E4F32_RS22605 () | 49669..50484 | - | 816 | WP_001043260.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | - |
| E4F32_RS22615 () | 50792..50968 | - | 177 | Protein_60 | replication protein C | - |
| E4F32_RS22620 () | 51029..51733 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| E4F32_RS22630 () | 51855..52760 | + | 906 | WP_000219391.1 | Mph(A) family macrolide 2'-phosphotransferase | - |
| E4F32_RS22635 () | 52757..53995 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| E4F32_RS22640 () | 53995..54579 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| E4F32_RS22655 () | 55072..55836 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| E4F32_RS23195 () | 55954..56019 | - | 66 | Protein_66 | EAL domain-containing protein | - |
| E4F32_RS22665 () | 56063..56368 | - | 306 | WP_000130000.1 | PadR family transcriptional regulator | - |
| E4F32_RS22670 () | 56379..57584 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| E4F32_RS22675 () | 57740..57943 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| E4F32_RS22685 () | 58071..58910 | - | 840 | WP_000259031.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | - |
| E4F32_RS22690 () | 58904..59251 | - | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| E4F32_RS22695 () | 59457..60245 | - | 789 | WP_000503573.1 | ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5 | - |
| E4F32_RS22700 () | 60376..60849 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| E4F32_RS22705 () | 61007..62020 | + | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| E4F32_RS22715 () | 62223..62573 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| E4F32_RS22720 () | 62699..62860 | + | 162 | Protein_76 | recombinase family protein | - |
| E4F32_RS22725 () | 62909..63613 | - | 705 | WP_073520228.1 | IS6-like element IS26 family transposase | - |
| E4F32_RS22730 () | 63638..64087 | + | 450 | WP_050491481.1 | recombinase family protein | - |
| E4F32_RS22735 () | 64090..67056 | + | 2967 | WP_001138064.1 | Tn3-like element TnAs3 family transposase | - |
| E4F32_RS22740 () | 67065..67481 | + | 417 | WP_031610367.1 | hypothetical protein | - |
| E4F32_RS22750 () | 68090..69058 | + | 969 | WP_032494872.1 | IS5 family transposase | - |
| E4F32_RS22760 () | 69290..69784 | - | 495 | WP_001442119.1 | hypothetical protein | - |
| E4F32_RS22765 () | 69840..70442 | - | 603 | WP_000517689.1 | hypothetical protein | - |
| E4F32_RS22775 () | 70796..72142 | + | 1347 | WP_001132019.1 | hypothetical protein | - |
| E4F32_RS22780 () | 72421..74301 | + | 1881 | WP_001283356.1 | colicin | - |
| E4F32_RS22785 () | 74319..74666 | - | 348 | WP_000762580.1 | hypothetical protein | - |
| E4F32_RS22790 () | 74785..75132 | + | 348 | WP_000142424.1 | hypothetical protein | - |
| E4F32_RS22795 () | 75150..75740 | - | 591 | WP_000194555.1 | hypothetical protein | - |
| E4F32_RS22800 () | 75737..75997 | - | 261 | WP_000343102.1 | hypothetical protein | - |
| E4F32_RS22810 () | 76568..76918 | + | 351 | WP_000493379.1 | hypothetical protein | - |
| E4F32_RS22815 () | 76962..77651 | + | 690 | WP_000796228.1 | hypothetical protein | - |
| E4F32_RS22820 () | 77648..78439 | + | 792 | WP_000016493.1 | site-specific integrase | - |
| E4F32_RS22825 () | 78617..78970 | + | 354 | WP_000864812.1 | colicin M immunity protein | - |
| E4F32_RS22830 () | 79020..79835 | - | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| E4F32_RS22840 () | 80079..80606 | + | 528 | WP_000203272.1 | colicin B immunity protein | - |
| E4F32_RS22845 () | 80624..80791 | - | 168 | Protein_96 | colicin-B | - |
| E4F32_RS22850 () | 80964..81245 | + | 282 | WP_001105066.1 | hypothetical protein | - |
| E4F32_RS22855 () | 81709..81945 | + | 237 | WP_014640552.1 | colicin V immunity protein | - |
| E4F32_RS22860 () | 81923..81997 | + | 75 | Protein_99 | colicin | - |
| E4F32_RS22865 () | 82049..82746 | + | 698 | Protein_100 | IS1 family transposase | - |
| E4F32_RS22870 () | 82758..82907 | + | 150 | Protein_101 | 3-deoxy-7-phosphoheptulonate synthase | - |
| E4F32_RS22885 () | 83762..85939 | + | 2178 | WP_072657522.1 | siderophore salmochelin receptor IroN | - |
| E4F32_RS22890 () | 85984..86940 | - | 957 | WP_000271276.1 | catecholate siderophore esterase IroE | - |
| E4F32_RS22895 () | 87025..88254 | - | 1230 | WP_001552738.1 | catecholate siderophore esterase IroD | - |
| E4F32_RS22900 () | 88358..92017 | - | 3660 | WP_001111199.1 | salmochelin/enterobactin export ABC transporter IroC | - |
| E4F32_RS22905 () | 92157..93272 | - | 1116 | WP_001318220.1 | salmochelin biosynthesis C-glycosyltransferase IroB | - |
| E4F32_RS22915 () | 94508..95608 | - | 1101 | Protein_107 | transposase | - |
| E4F32_RS22925 () | 96162..96361 | + | 200 | Protein_108 | lysis system i-spanin subunit Rz | - |
| E4F32_RS22930 () | 96419..96712 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| E4F32_RS22940 () | 97219..97923 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| E4F32_RS22950 () | 97976..98641 | + | 666 | Protein_111 | IS110-like element ISEc32 family transposase | - |
| E4F32_RS22955 () | 98655..99352 | - | 698 | Protein_112 | IS1 family transposase | - |
| E4F32_RS22960 () | 99406..99738 | - | 333 | Protein_113 | hypothetical protein | - |
| E4F32_RS23330 () | 99807..100145 | - | 339 | WP_201758402.1 | hypothetical protein | - |
| E4F32_RS22980 () | 101086..102057 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| E4F32_RS22985 () | 102057..103223 | - | 1167 | WP_001238646.1 | plasmid-partitioning protein SopA | - |
| E4F32_RS22990 () | 103523..104220 | - | 698 | Protein_117 | IS1 family transposase | - |
| E4F32_RS22995 () | 104376..105878 | - | 1503 | WP_072657541.1 | hypothetical protein | - |
| E4F32_RS23000 () | 106497..106946 | - | 450 | WP_000238252.1 | hypothetical protein | - |
| E4F32_RS23005 () | 107064..107543 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| E4F32_RS23015 () | 107983..108210 | + | 228 | Protein_121 | malate dehydrogenase | - |
| E4F32_RS23020 () | 108207..108338 | - | 132 | Protein_122 | phosphopyruvate hydratase | - |
| E4F32_RS23025 () | 108336..108593 | + | 258 | Protein_123 | Tn3 family transposase | - |
| E4F32_RS23030 () | 108827..109684 | - | 858 | WP_000968139.1 | iron/manganese ABC transporter permease subunit SitD | - |
| E4F32_RS23035 () | 109681..110538 | - | 858 | WP_000992806.1 | iron/manganese ABC transporter permease subunit SitC | - |
| E4F32_RS23040 () | 110535..111362 | - | 828 | WP_000983710.1 | iron/manganese ABC transporter ATP-binding protein SitB | - |
| E4F32_RS23045 () | 111362..112276 | - | 915 | WP_000949004.1 | iron/manganese ABC transporter substrate-binding protein SitA | - |
| E4F32_RS23055 () | 112632..113329 | + | 698 | Protein_128 | IS1 family transposase | - |
| E4F32_RS23060 () | 113509..114022 | - | 514 | Protein_129 | DUF4113 domain-containing protein | - |
| E4F32_RS23065 () | 114083..114187 | - | 105 | Protein_130 | AAA family ATPase | - |
| E4F32_RS23070 () | 114189..114512 | - | 324 | Protein_131 | helix-turn-helix domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|