MGE detailed information
MGE type: Conjugative plasmid MGE length: 93485 bp
Accession: NZ_CP035844 Location: 1..93485 Organism: Escherichia coli strain TW10722 Replicon: plasmid pTW10722_93
Accession: NZ_CP035844 Location: 1..93485 Organism: Escherichia coli strain TW10722 Replicon: plasmid pTW10722_93
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EXA02_RS27380 (447) | 447..737 | - | 291 | WP_000754127.1 | DUF2282 domain-containing protein | - |
| EXA02_RS27385 (1046) | 1046..1603 | - | 558 | WP_000103553.1 | hypothetical protein | VF |
| EXA02_RS27390 (2251) | 2251..2817 | + | 567 | WP_000587874.1 | hypothetical protein | - |
| EXA02_RS27395 (2885) | 2885..3004 | - | 120 | Protein_4 | transposase domain-containing protein | - |
| EXA02_RS27400 (3206) | 3206..4186 | + | 981 | WP_001218105.1 | plasmid segregation protein ParM | - |
| EXA02_RS27405 (4189) | 4189..4611 | + | 423 | WP_000774834.1 | plasmid partitioning/stability family protein | - |
| EXA02_RS28550 (4635) | 4635..4925 | + | 291 | WP_072130272.1 | hypothetical protein | - |
| EXA02_RS27410 (5020) | 5020..5922 | + | 903 | WP_077627215.1 | DUF1281 domain-containing protein | - |
| EXA02_RS27415 (5926) | 5926..6231 | + | 306 | WP_013307862.1 | hypothetical protein | - |
| EXA02_RS27420 (6307) | 6307..6990 | + | 684 | WP_000086128.1 | DNA methylase | - |
| EXA02_RS27425 (6991) | 6991..7212 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| EXA02_RS27430 (7142) | 7142..7660 | + | 519 | WP_235837487.1 | DUF1380 family protein | - |
| EXA02_RS27435 (7705) | 7705..8475 | + | 771 | WP_001006243.1 | hypothetical protein | - |
| EXA02_RS27440 (8888) | 8888..9313 | + | 426 | WP_001198880.1 | antirestriction protein | - |
| EXA02_RS27445 (9360) | 9360..9782 | + | 423 | WP_000271739.1 | DUF1380 family protein | - |
| EXA02_RS27450 (9779) | 9779..9970 | + | 192 | WP_001024838.1 | hypothetical protein | - |
| EXA02_RS28555 (10301) | 10301..10474 | - | 174 | Protein_17 | hypothetical protein | - |
| EXA02_RS27460 (10972) | 10972..11202 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| EXA02_RS27465 (11254) | 11254..12615 | + | 1362 | WP_000170656.1 | DUF3560 domain-containing protein | - |
| EXA02_RS27470 (12661) | 12661..13224 | + | 564 | WP_001297832.1 | class I SAM-dependent methyltransferase | - |
| EXA02_RS28560 (13310) | 13310..13736 | - | 427 | Protein_21 | hypothetical protein | - |
| EXA02_RS27475 (14038) | 14038..14565 | + | 528 | WP_000290805.1 | single-stranded DNA-binding protein | - |
| EXA02_RS27480 (14622) | 14622..14855 | + | 234 | WP_000005968.1 | DUF905 domain-containing protein | - |
| EXA02_RS27485 (14917) | 14917..16884 | + | 1968 | WP_000117113.1 | ParB/RepB/Spo0J family partition protein | - |
| EXA02_RS27490 (16939) | 16939..17373 | + | 435 | WP_000845922.1 | conjugation system SOS inhibitor PsiB | - |
| EXA02_RS27495 (17370) | 17370..18089 | + | 720 | WP_000994093.1 | plasmid SOS inhibition protein A | - |
| EXA02_RS27500 (18086) | 18086..18400 | + | 315 | WP_000872086.1 | hypothetical protein | - |
| - (18357) | 18357..18542 | + | 186 | NuclAT_0 | - | Antitoxin Detail |
| - (18357) | 18357..18542 | + | 186 | NuclAT_0 | - | Antitoxin Detail |
| - (18357) | 18357..18542 | + | 186 | NuclAT_0 | - | Antitoxin Detail |
| - (18357) | 18357..18542 | + | 186 | NuclAT_0 | - | Antitoxin Detail |
| EXA02_RS28565 (18550) | 18550..18702 | + | 153 | Protein_28 | FlmC family protein | - |
| EXA02_RS27505 (18647) | 18647..18769 | + | 123 | WP_223195199.1 | Hok/Gef family protein | Toxin Detail |
| EXA02_RS27510 (19007) | 19007..19385 | - | 379 | Protein_30 | hypothetical protein | - |
| EXA02_RS27515 (19686) | 19686..19967 | + | 282 | WP_000107523.1 | hypothetical protein | - |
| EXA02_RS27520 (20009) | 20009..20251 | + | 243 | WP_000540593.1 | hypothetical protein | - |
| EXA02_RS27525 (20592) | 20592..20807 | + | 216 | WP_024179973.1 | hypothetical protein | - |
| EXA02_RS27530 (20968) | 20968..21129 | - | 162 | Protein_34 | IS3 family transposase ISEc48 | Transposase |
| EXA02_RS27535 (21265) | 21265..21717 | - | 453 | WP_000163902.1 | hypothetical protein | VF |
| EXA02_RS27540 (22189) | 22189..22575 | + | 387 | WP_001137405.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| EXA02_RS27545 (23054) | 23054..23335 | + | 282 | WP_000974580.1 | hypothetical protein | - |
| EXA02_RS27550 (23551) | 23551..23718 | + | 168 | WP_157187929.1 | hypothetical protein | - |
| EXA02_RS27555 (23815) | 23815..24174 | + | 360 | WP_001054220.1 | type IV conjugative transfer system pilin TraA | - |
| EXA02_RS27560 (24176) | 24176..24481 | + | 306 | WP_000016323.1 | type IV conjugative transfer system protein TraL | - |
| EXA02_RS27565 (24501) | 24501..25064 | + | 564 | WP_000406020.1 | type IV conjugative transfer system protein TraE | - |
| EXA02_RS27570 (25054) | 25054..25794 | + | 741 | WP_000794311.1 | type-F conjugative transfer system secretin TraK | - |
| EXA02_RS27575 (25781) | 25781..27145 | + | 1365 | WP_000024505.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| EXA02_RS27580 (27257) | 27257..27481 | + | 225 | WP_000786056.1 | TraR/DksA C4-type zinc finger protein | - |
| EXA02_RS27585 (27485) | 27485..27670 | + | 186 | WP_000797318.1 | hypothetical protein | - |
| EXA02_RS27590 (27654) | 27654..28064 | + | 411 | WP_000210715.1 | hypothetical protein | - |
| EXA02_RS27595 (28124) | 28124..28723 | + | 600 | WP_000724374.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EXA02_RS27600 (28734) | 28734..31325 | + | 2592 | WP_000714172.1 | type IV secretion system protein TraC | - |
| EXA02_RS27605 (31322) | 31322..31786 | + | 465 | WP_000206177.1 | type-F conjugative transfer system protein TrbI | - |
| EXA02_RS27610 (31786) | 31786..32421 | + | 636 | WP_000286241.1 | type-F conjugative transfer system protein TraW | - |
| EXA02_RS27615 (32418) | 32418..33404 | + | 987 | WP_001083233.1 | conjugal transfer pilus assembly protein TraU | - |
| EXA02_RS27620 (33415) | 33415..33783 | + | 369 | WP_000961326.1 | hypothetical protein | - |
| EXA02_RS27625 (33780) | 33780..34394 | + | 615 | WP_000832605.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EXA02_RS27630 (34391) | 34391..36229 | + | 1839 | WP_000833261.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EXA02_RS27635 (36226) | 36226..37005 | + | 780 | WP_001202909.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EXA02_RS27640 (37029) | 37029..37631 | + | 603 | WP_000906492.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EXA02_RS27645 (37637) | 37637..38998 | + | 1362 | WP_001237467.1 | conjugal transfer pilus assembly protein TraH | - |
| EXA02_RS27650 (39000) | 39000..41903 | + | 2904 | WP_000963405.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| EXA02_RS27655 (41913) | 41913..42470 | + | 558 | WP_001232424.1 | hypothetical protein | - |
| EXA02_RS27660 (42666) | 42666..43382 | + | 717 | WP_235836318.1 | conjugal transfer complement resistance protein TraT | - |
| EXA02_RS27665 (43526) | 43526..45757 | + | 2232 | WP_000056171.1 | type IV conjugative transfer system coupling protein TraD | - |
| EXA02_RS27670 (45757) | 45757..51054 | + | 5298 | WP_000949137.1 | Multifunctional conjugation protein TraI | Relaxase |
| EXA02_RS27675 (51072) | 51072..51638 | + | 567 | WP_000469210.1 | DUF2726 domain-containing protein | - |
| EXA02_RS27680 (51635) | 51635..52366 | + | 732 | WP_001076475.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| EXA02_RS27685 (52425) | 52425..54038 | - | 1614 | WP_001744949.1 | IS66 family transposase ISEc47 | Transposase |
| EXA02_RS27690 (54069) | 54069..54419 | - | 351 | WP_000624688.1 | IS66 family transposase ISEc47 | Transposase |
| EXA02_RS27695 (54416) | 54416..54850 | - | 435 | WP_001403014.1 | IS66 family transposase ISEc43 | Transposase |
| EXA02_RS27700 (54957) | 54957..55310 | + | 354 | WP_000792062.1 | hypothetical protein | - |
| EXA02_RS27705 (55307) | 55307..56017 | + | 711 | WP_000007774.1 | hypothetical protein | - |
| EXA02_RS27710 (56014) | 56014..56322 | + | 309 | WP_000636895.1 | hypothetical protein | - |
| EXA02_RS27715 (56429) | 56429..57442 | + | 1014 | WP_000118342.1 | hypothetical protein | - |
| EXA02_RS27720 (57525) | 57525..57761 | + | 237 | WP_032274049.1 | hypothetical protein | - |
| EXA02_RS27725 (57821) | 57821..58030 | + | 210 | WP_024234785.1 | hemolysin expression modulator Hha | - |
| - (58271) | 58271..58327 | - | 57 | NuclAT_1 | - | - |
| - (58271) | 58271..58327 | - | 57 | NuclAT_1 | - | - |
| - (58271) | 58271..58327 | - | 57 | NuclAT_1 | - | - |
| - (58271) | 58271..58327 | - | 57 | NuclAT_1 | - | - |
| EXA02_RS27730 (58376) | 58376..58525 | + | 150 | WP_064758536.1 | Hok/Gef family protein | - |
| EXA02_RS27735 (58809) | 58809..59069 | + | 261 | WP_000078108.1 | replication regulatory protein RepA | - |
| EXA02_RS27740 (59307) | 59307..59381 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| EXA02_RS27745 (59374) | 59374..60231 | + | 858 | WP_000130987.1 | incFII family plasmid replication initiator RepA | - |
| EXA02_RS27750 (61173) | 61173..61826 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| EXA02_RS27755 (61919) | 61919..62176 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EXA02_RS27760 (62109) | 62109..62510 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| EXA02_RS27765 (62826) | 62826..63523 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| EXA02_RS27770 (63633) | 63633..64067 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| EXA02_RS27775 (64139) | 64139..64228 | + | 90 | Protein_83 | mercuric transporter MerT family protein | - |
| EXA02_RS27780 (64262) | 64262..67267 | - | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| EXA02_RS27785 (67431) | 67431..67988 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EXA02_RS27790 (68171) | 68171..69031 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| EXA02_RS27795 (69192) | 69192..69689 | + | 498 | Protein_87 | mercuric reductase | - |
| EXA02_RS27800 (69707) | 69707..70069 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| EXA02_RS27805 (70066) | 70066..70302 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| EXA02_RS27810 (70338) | 70338..71006 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| EXA02_RS27815 (71081) | 71081..71764 | + | 684 | Protein_91 | transposase | - |
| EXA02_RS27820 (71773) | 71773..72633 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| EXA02_RS27825 (72665) | 72665..73864 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| EXA02_RS27830 (73970) | 73970..74620 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| EXA02_RS27835 (74652) | 74652..74894 | - | 243 | WP_000844627.1 | transposase | - |
| EXA02_RS27840 (75882) | 75882..76993 | - | 1112 | Protein_96 | IS4 family transposase IS186B | Transposase |
| EXA02_RS27845 (77047) | 77047..77370 | - | 324 | Protein_97 | GNAT family N-acetyltransferase | - |
| EXA02_RS27850 (77498) | 77498..78337 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| EXA02_RS27855 (78331) | 78331..78678 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| EXA02_RS27860 (78795) | 78795..79633 | - | 839 | Protein_100 | Streptomycin 3''-adenylyltransferase | ARG |
| EXA02_RS27865 (79735) | 79735..80208 | - | 474 | WP_001355915.1 | Dihydrofolate reductase type 1 | ARG |
| EXA02_RS27870 (80365) | 80365..81378 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| EXA02_RS27875 (81581) | 81581..81931 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| EXA02_RS27880 (82057) | 82057..82617 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| EXA02_RS27885 (82620) | 82620..85586 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| EXA02_RS27890 (85801) | 85801..86976 | + | 1176 | WP_001067907.1 | DUF3800 domain-containing protein | - |
| EXA02_RS27895 (87178) | 87178..87740 | + | 563 | Protein_107 | IS3 family transposase IS2 | Transposase |
| EXA02_RS27900 (87933) | 87933..89120 | - | 1188 | Protein_108 | IS91 family transposase IS91 | Transposase |
| EXA02_RS27905 (89120) | 89120..89485 | - | 366 | WP_000124103.1 | hypothetical protein | - |
| EXA02_RS27910 (90013) | 90013..90522 | + | 510 | WP_000115001.1 | peptide deformylase | - |
| EXA02_RS27915 (90537) | 90537..90638 | + | 102 | Protein_111 | methionyl-tRNA formyltransferase | - |
| EXA02_RS27920 (90835) | 90835..91026 | + | 192 | WP_000175572.1 | DUF2164 family protein | - |
| EXA02_RS27925 (91023) | 91023..91385 | + | 363 | WP_000181069.1 | hypothetical protein | - |
| EXA02_RS27930 (91718) | 91718..92245 | - | 528 | WP_001196880.1 | DoxX family protein | - |
| EXA02_RS27935 (92247) | 92247..93005 | - | 759 | WP_001181586.1 | DNA-binding domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|