MGE detailed information
MGE type: Conjugative plasmid MGE length: 149312 bp
Accession: NZ_CP035478 Location: 1..149312 Organism: Escherichia coli strain U13A Replicon: plasmid pU13A_A
Accession: NZ_CP035478 Location: 1..149312 Organism: Escherichia coli strain U13A Replicon: plasmid pU13A_A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| U13A_RS25220 () | 49..1359 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| U13A_RS25225 () | 1644..2045 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| U13A_RS25230 () | 1978..2235 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| U13A_RS25235 () | 2328..2981 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| U13A_RS25245 () | 3921..4778 | - | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| U13A_RS25250 () | 4771..4845 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| U13A_RS27160 () | 4842..4976 | - | 135 | Protein_7 | protein CopA/IncA | - |
| U13A_RS25260 () | 5082..5336 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| U13A_RS25265 () | 5633..5767 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 5812..5872 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 5812..5872 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 5812..5872 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 5812..5872 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| U13A_RS27005 () | 5839..6125 | - | 287 | Protein_10 | DUF2726 domain-containing protein | - |
| U13A_RS25275 () | 6203..7816 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| U13A_RS25280 () | 7847..8197 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| U13A_RS25285 () | 8194..8619 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| U13A_RS25295 () | 9178..9390 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| U13A_RS25300 () | 9521..10081 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| U13A_RS25305 () | 10136..10882 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| U13A_RS25310 () | 10902..16172 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| U13A_RS25315 () | 16172..18370 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| U13A_RS27165 () | 18367..19141 | - | 775 | Protein_19 | hypothetical protein | - |
| U13A_RS25325 () | 19344..20075 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| U13A_RS25330 () | 20107..20604 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| U13A_RS25335 () | 20623..23442 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| U13A_RS25340 () | 23439..24812 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| U13A_RS25345 () | 24799..25224 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| U13A_RS25350 () | 25172..25519 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| U13A_RS25355 () | 25449..25994 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| U13A_RS25360 () | 25981..26265 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| U13A_RS25365 () | 26392..26712 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| U13A_RS25370 () | 26760..27457 | - | 698 | Protein_29 | IS1 family transposase IS1G | Transposase |
| U13A_RS25375 () | 27612..28592 | - | 981 | WP_000019450.1 | IS5 family transposase ISKpn26 | Transposase |
| U13A_RS25380 () | 28722..29465 | - | 744 | WP_001030401.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| U13A_RS25385 () | 29458..29715 | - | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| U13A_RS25390 () | 29742..31592 | - | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| U13A_RS25395 () | 31589..32227 | - | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| U13A_RS25400 () | 32236..32541 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| U13A_RS25405 () | 32571..33563 | - | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| U13A_RS25410 () | 33560..34192 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| U13A_RS25415 () | 34189..34575 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| U13A_RS25420 () | 34572..37199 | - | 2628 | WP_001064258.1 | type IV secretion system protein TraC | - |
| U13A_RS25425 () | 37359..37580 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| U13A_RS25430 () | 37715..38230 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| U13A_RS25435 () | 38230..38589 | - | 360 | WP_001617876.1 | conjugal transfer protein TrbD | - |
| U13A_RS25440 () | 38528..39115 | - | 588 | WP_013023871.1 | conjugal transfer protein TraP | - |
| U13A_RS25445 () | 39084..40535 | - | 1452 | WP_000146687.1 | conjugal transfer protein TraB | - |
| U13A_RS25450 () | 40535..41239 | - | 705 | WP_148725207.1 | type-F conjugative transfer system secretin TraK | - |
| U13A_RS25455 () | 41250..41816 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| U13A_RS25460 () | 41838..42149 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| U13A_RS25465 () | 42154..42516 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| U13A_RS25470 () | 42550..42777 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| U13A_RS25475 () | 42865..43542 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| U13A_RS25480 () | 43676..44059 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| U13A_RS25485 () | 44390..44992 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| U13A_RS25490 () | 45289..46110 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| U13A_RS25495 () | 46229..46516 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| U13A_RS27170 () | 46541..46747 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| U13A_RS27175 () | 46660..46995 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| U13A_RS25515 () | 47438..47596 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 47640..47680 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 47640..47680 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 47640..47680 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 47640..47680 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 49124..49310 | - | 187 | NuclAT_0 | - | - |
| - () | 49124..49310 | - | 187 | NuclAT_0 | - | - |
| - () | 49124..49310 | - | 187 | NuclAT_0 | - | - |
| - () | 49124..49310 | - | 187 | NuclAT_0 | - | - |
| U13A_RS25525 () | 49322..50041 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| U13A_RS25530 () | 50038..50472 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| U13A_RS25535 () | 50527..52485 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| U13A_RS25540 () | 52551..52784 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| U13A_RS25545 () | 52847..53386 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| U13A_RS25570 () | 54029..54265 | - | 237 | WP_032153960.1 | hypothetical protein | - |
| U13A_RS25575 () | 54291..54854 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| U13A_RS25580 () | 54902..56263 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| U13A_RS25585 () | 56315..56545 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| U13A_RS25595 () | 57580..57771 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| U13A_RS25600 () | 57768..58190 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| U13A_RS25605 () | 58237..58539 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| U13A_RS25615 () | 59079..59855 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| U13A_RS25620 () | 59906..60340 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| U13A_RS25625 () | 60354..60575 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| U13A_RS25630 () | 60576..61259 | - | 684 | WP_000086185.1 | DNA methylase | - |
| U13A_RS25635 () | 61336..61640 | - | 305 | Protein_75 | hypothetical protein | - |
| U13A_RS25640 () | 61644..62546 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| U13A_RS25655 () | 63413..64384 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| U13A_RS25660 () | 64384..65550 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| U13A_RS25665 () | 66138..66893 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| U13A_RS25670 () | 67667..68473 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| U13A_RS25675 () | 68474..68779 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| U13A_RS25680 () | 68781..68999 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| U13A_RS25685 () | 69707..70702 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| U13A_RS25690 () | 70706..71638 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| U13A_RS25695 () | 71775..72472 | - | 698 | Protein_85 | IS1 family transposase IS1G | Transposase |
| U13A_RS25700 () | 72686..75802 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| U13A_RS25705 () | 75924..77207 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| U13A_RS25710 () | 77204..78760 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| U13A_RS25715 () | 78943..79164 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| U13A_RS25720 () | 79164..79544 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| U13A_RS25725 () | 79549..79728 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| U13A_RS25730 () | 79756..80115 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| U13A_RS25735 () | 80039..80452 | + | 414 | Protein_93 | IS3 family transposase ISLad1 | Transposase |
| U13A_RS25740 () | 80402..80719 | - | 318 | WP_001513659.1 | hypothetical protein | - |
| U13A_RS25745 () | 80947..81927 | - | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| U13A_RS25750 () | 82171..83574 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| U13A_RS25755 () | 83561..84493 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| U13A_RS25760 () | 84602..84931 | - | 330 | Protein_98 | TOBE domain-containing protein | - |
| U13A_RS25765 () | 84947..85644 | - | 698 | Protein_99 | IS1 family transposase IS1R | Transposase |
| U13A_RS25770 () | 85702..85950 | + | 249 | Protein_100 | abortive infection family protein | - |
| U13A_RS25775 () | 86319..87050 | - | 732 | WP_001617898.1 | hypothetical protein | - |
| U13A_RS25785 () | 87836..88813 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| U13A_RS25790 () | 89098..89838 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| U13A_RS25795 () | 89959..90147 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| U13A_RS25800 () | 90514..91683 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| U13A_RS25805 () | 91909..92084 | - | 176 | Protein_106 | IS3 family transposase | - |
| U13A_RS25810 () | 92530..92802 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| U13A_RS25815 () | 93327..93763 | - | 437 | Protein_108 | IS3 family transposase IS2 | Transposase |
| U13A_RS25820 () | 94045..96015 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| U13A_RS25825 () | 96022..96813 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| U13A_RS25830 () | 96876..97484 | - | 609 | Protein_111 | IS66 family transposase ISEc22 | Transposase |
| U13A_RS25835 () | 97552..98334 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| U13A_RS25840 () | 98331..99353 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| U13A_RS25845 () | 99439..100384 | - | 946 | Protein_114 | IS66 family transposase ISEc8 | Transposase |
| U13A_RS25850 () | 100433..100780 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| U13A_RS25855 () | 100777..101181 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| U13A_RS25860 () | 101210..101593 | - | 384 | Protein_117 | IS3 family transposase IS629 | Transposase |
| U13A_RS25865 () | 101683..103191 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| U13A_RS25875 () | 103864..104603 | - | 740 | Protein_119 | IS3 family transposase IS629 | Transposase |
| U13A_RS25880 () | 104629..104934 | + | 306 | Protein_120 | IS91 family transposase ISSbo1 | Transposase |
| U13A_RS25885 () | 105457..106632 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| U13A_RS25895 () | 106701..108962 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| U13A_RS25900 () | 109131..109907 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| U13A_RS25905 () | 109915..110790 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| U13A_RS25910 () | 111122..111669 | - | 548 | Protein_125 | primase alpha helix C-terminal domain-containing protein | - |
| U13A_RS25935 () | 113241..113576 | - | 336 | WP_001080732.1 | colicin transporter | - |
| U13A_RS25940 () | 113705..114052 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| U13A_RS25945 () | 114072..114581 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| U13A_RS25950 () | 114578..114838 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| U13A_RS25955 () | 114940..115679 | + | 740 | Protein_130 | IS3 family transposase IS629 | Transposase |
| U13A_RS27180 () | 116352..116666 | + | 315 | Protein_131 | IS5 family transposase ISKpn26 | Transposase |
| U13A_RS27185 () | 116667..116840 | + | 174 | Protein_132 | IS5 family transposase ISKpn26 | Transposase |
| U13A_RS25970 () | 116990..117623 | - | 634 | Protein_133 | histidine-type phosphatase | - |
| U13A_RS25975 () | 117745..118230 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| U13A_RS25980 () | 118255..118740 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| U13A_RS25985 () | 118727..119422 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| U13A_RS25990 () | 119427..120557 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| U13A_RS25995 () | 120547..121830 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| U13A_RS26000 () | 121833..123212 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| U13A_RS26005 () | 123316..123843 | - | 528 | WP_000178050.1 | iron transporter | - |
| U13A_RS26010 () | 123884..125770 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| U13A_RS26020 () | 126117..126932 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| U13A_RS26025 () | 127115..127621 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| U13A_RS26030 () | 127611..127769 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| U13A_RS27190 () | 127919..128032 | - | 114 | Protein_145 | IS6 family transposase | - |
| U13A_RS26045 () | 128232..128905 | + | 674 | Protein_146 | IS1 family transposase IS1X2 | Transposase |
| U13A_RS26050 () | 128958..129662 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| U13A_RS26055 () | 129721..130470 | - | 750 | Protein_148 | IS91 family transposase ISAzo26 | Transposase |
| U13A_RS26060 () | 130628..131101 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| U13A_RS26065 () | 131232..132020 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| U13A_RS26070 () | 132226..132573 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| U13A_RS26075 () | 132567..133406 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| U13A_RS26085 () | 133534..133737 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| U13A_RS26090 () | 133893..135098 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| U13A_RS26095 () | 135109..135414 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| U13A_RS27010 () | 135458..135523 | + | 66 | Protein_156 | EAL domain-containing protein | - |
| U13A_RS26105 () | 135641..136405 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| U13A_RS26120 () | 136898..137482 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| U13A_RS26125 () | 137482..138720 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| U13A_RS26130 () | 138717..139622 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| U13A_RS26140 () | 139744..140448 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| U13A_RS26145 () | 140509..140685 | + | 177 | Protein_162 | replication protein C | - |
| U13A_RS26155 () | 140993..141808 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| U13A_RS26160 () | 141869..142672 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| U13A_RS26165 () | 142672..143508 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| U13A_RS26170 () | 143562..143798 | + | 237 | WP_042005022.1 | hypothetical protein | - |
| U13A_RS26175 () | 143830..144456 | - | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| U13A_RS26180 () | 144562..145761 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| U13A_RS26185 () | 145793..146653 | - | 861 | WP_000493383.1 | EamA family transporter | - |
| U13A_RS26190 () | 146662..147168 | - | 507 | Protein_170 | transposase | - |
| U13A_RS26200 () | 147221..147925 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| U13A_RS26205 () | 148224..149084 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|