MGE detailed information

MGE type: Conjugative plasmid        MGE length: 76559 bp
Accession: NZ_CP034592        Location: 1..76559         Organism: Escherichia coli strain L37       Replicon: plasmid pL37-4


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKM58_RS23235 () 1705..6975 + 5271 WP_053320757.1 Multifunctional conjugation protein TraI Relaxase
EKM58_RS23240 () 6995..7738 + 744 WP_000205704.1 conjugal transfer pilus acetylase TraX -
EKM58_RS23245 () 7793..8353 + 561 WP_024184455.1 fertility inhibition protein FinO -
EKM58_RS23250 () 8489..8701 + 213 WP_001299730.1 ANR family transcriptional regulator -
EKM58_RS23260 () 8987..11536 + 2550 WP_053320758.1 DEAD/DEAH box helicase family protein -
EKM58_RS23265 () 11582..13615 + 2034 WP_000887497.1 N-6 DNA methylase -
EKM58_RS23270 () 13680..16535 + 2856 WP_053320759.1 chromosome segregation protein SMC -
EKM58_RS23275 () 17477..17737 + 261 WP_000078108.1 replication regulatory protein RepA -
EKM58_RS23280 () 17972..18046 + 75 WP_001365705.1 RepA leader peptide Tap -
EKM58_RS23285 () 18039..18896 + 858 WP_065800511.1 incFII family plasmid replication initiator RepA -
EKM58_RS23295 () 19835..20488 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
EKM58_RS23300 () 20581..20838 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
EKM58_RS23305 () 20771..21172 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
EKM58_RS23310 () 21421..21836 + 416 Protein_14 IS1 family transposase IS1R Transposase
EKM58_RS23315 () 21872..22417 - 546 Protein_15 Tn3 family transposase TnpA_Tn3 Transposase
EKM58_RS23320 () 22483..23186 - 704 Protein_16 IS6 family transposase IS15DII Transposase
EKM58_RS23325 () 23251..23932 - 682 Protein_17 IS91 family transposase ISCARN110 Transposase
EKM58_RS23330 () 24204..24910 + 707 Protein_18 IS6 family transposase -
EKM58_RS23340 () 24920..25390 + 471 WP_049824851.1 TetR family transcriptional regulator -
EKM58_RS23345 () 25410..26198 + 789 WP_014839978.1 winged helix-turn-helix domain-containing protein -
EKM58_RS23350 () 26198..26716 + 519 WP_014839979.1 hypothetical protein -
EKM58_RS23355 () 26721..27137 - 417 WP_014839980.1 Glutathione transferase FosA ARG
EKM58_RS23360 () 27523..28227 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
EKM58_RS23365 () 28277..29020 + 744 Protein_24 Beta-lactamase TEM ARG
EKM58_RS23370 () 29279..29755 + 477 WP_013023839.1 WbuC family cupin fold metalloprotein -
EKM58_RS23375 () 29802..30677 - 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
EKM58_RS23380 () 31099..31803 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
EKM58_RS24015 () 31869..31934 + 66 Protein_28 IS1 family transposase -
EKM58_RS23400 () 33383..33617 + 235 Protein_29 type II toxin-antitoxin system RelE/ParE family toxin -
EKM58_RS23405 () 33745..34026 + 282 WP_001333089.1 hypothetical protein -
EKM58_RS23410 () 34149..34499 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
EKM58_RS23415 () 34502..35464 - 963 WP_000959884.1 plasmid segregation protein ParM -
EKM58_RS23420 () 35611..35904 + 294 WP_032146011.1 hypothetical protein -
EKM58_RS23430 () 35981..36664 + 684 WP_000085883.1 DNA methylase -
EKM58_RS23435 () 36665..36886 + 222 WP_001104881.1 hypothetical protein -
EKM58_RS23440 () 36900..37334 + 435 WP_000274503.1 DUF1380 family protein -
EKM58_RS24020 () 37385..38161 + 777 WP_001383963.1 hypothetical protein -
EKM58_RS23455 () 38702..39004 + 303 WP_001671341.1 antirestriction protein -
EKM58_RS23460 () 39051..39473 + 423 WP_000271762.1 DUF1380 family protein -
EKM58_RS23465 () 39470..39661 + 192 WP_001027493.1 hypothetical protein -
EKM58_RS23475 () 40699..40929 + 231 WP_000218642.1 hypothetical protein -
EKM58_RS23480 () 40981..42342 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
EKM58_RS23485 () 42389..42952 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
EKM58_RS23510 () 43802..44329 + 528 WP_000290834.1 single-stranded DNA-binding protein -
EKM58_RS23515 () 44387..44620 + 234 WP_000006003.1 DUF905 family protein -
EKM58_RS23520 () 44681..46704 + 2024 Protein_46 ParB/RepB/Spo0J family partition protein -
EKM58_RS23525 () 46773..47207 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
EKM58_RS23530 () 47204..47923 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- () 47935..48159 + 225 NuclAT_0 - -
- () 47935..48159 + 225 NuclAT_0 - -
- () 47935..48159 + 225 NuclAT_0 - -
- () 47935..48159 + 225 NuclAT_0 - -
EKM58_RS23920 () 47944..48123 - 180 WP_001309233.1 hypothetical protein -
- () 48092..48157 + 66 - - Antitoxin Detail
EKM58_RS23535 () 48203..48361 + 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
EKM58_RS24025 () 48599..48976 - 378 Protein_51 hypothetical protein -
EKM58_RS23555 () 49276..49572 + 297 WP_001272251.1 hypothetical protein -
EKM58_RS23560 () 49683..50504 + 822 WP_001234445.1 DUF945 domain-containing protein -
EKM58_RS23565 () 50801..51448 - 648 WP_015059008.1 hypothetical protein VF
EKM58_RS23570 () 51725..52108 + 384 WP_000124981.1 relaxosome protein TraM -
EKM58_RS23575 () 52299..52985 + 687 WP_015059009.1 PAS domain-containing protein -
EKM58_RS23580 () 53079..53306 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
EKM58_RS23585 () 53340..53705 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
EKM58_RS23590 () 53720..54031 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
EKM58_RS23595 () 54053..54619 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
EKM58_RS23600 () 54630..55334 + 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
EKM58_RS23605 () 55334..56761 + 1428 WP_032297072.1 conjugal transfer protein TraB -
EKM58_RS23610 () 56751..57341 + 591 WP_000002778.1 conjugal transfer protein TraP -
EKM58_RS23615 () 57295..57525 + 231 WP_001352845.1 conjugal transfer protein TrbD -
EKM58_RS23620 () 57537..57788 + 252 WP_001038341.1 conjugal transfer protein TrbG -
EKM58_RS23625 () 57785..58300 + 516 WP_000809902.1 type IV conjugative transfer system lipoprotein TraV -
EKM58_RS23630 () 58435..58656 + 222 WP_001278692.1 conjugal transfer protein TraR -
EKM58_RS23635 () 58816..61443 + 2628 WP_015059012.1 type IV secretion system protein TraC -
EKM58_RS23640 () 61440..61826 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
EKM58_RS23645 () 61823..62455 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
EKM58_RS23650 () 62452..63444 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
EKM58_RS23655 () 63471..63779 + 309 WP_000412447.1 hypothetical protein -
EKM58_RS23660 () 63842..64363 + 522 WP_015059014.1 hypothetical protein -
EKM58_RS23665 () 64390..65028 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
EKM58_RS23670 () 65025..65396 + 372 WP_000056336.1 hypothetical protein -
EKM58_RS23675 () 65422..65844 + 423 WP_001229309.1 HNH endonuclease -
EKM58_RS23680 () 65841..67691 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
EKM58_RS23685 () 67718..67975 + 258 WP_053913405.1 conjugal transfer protein TrbE -
EKM58_RS23690 () 67968..68711 + 744 WP_015059017.1 type-F conjugative transfer system pilin assembly protein TraF -
EKM58_RS23695 () 68827..69108 + 282 WP_000549793.1 type-F conjugative transfer system pilin chaperone TraQ -
EKM58_RS23700 () 69095..69640 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
EKM58_RS23705 () 69570..69944 + 375 WP_071776752.1 P-type conjugative transfer protein TrbJ -
EKM58_RS23710 () 69898..70290 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
EKM58_RS23715 () 70277..71650 + 1374 WP_000944325.1 conjugal transfer protein TraH -
EKM58_RS23720 () 71647..74469 + 2823 WP_053320755.1 conjugal transfer mating pair stabilization protein TraG -
EKM58_RS23725 () 74484..74987 + 504 WP_053320762.1 surface exclusion protein -
EKM58_RS23730 () 75019..75750 + 732 WP_000850424.1 complement resistance protein TraT -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance