MGE detailed information
MGE type: Conjugative plasmid MGE length: 134635 bp
Accession: NZ_CP034396 Location: 1..134635 Organism: Escherichia coli strain CRE1 Replicon: plasmid pCRE1.1
Accession: NZ_CP034396 Location: 1..134635 Organism: Escherichia coli strain CRE1 Replicon: plasmid pCRE1.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EJC48_RS00010 () | 941..1846 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| EJC48_RS00020 () | 1968..2672 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EJC48_RS00025 () | 2831..3112 | - | 282 | Protein_3 | transposase zinc-binding domain-containing protein | - |
| EJC48_RS00030 () | 3259..4119 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| EJC48_RS00035 () | 4302..4640 | - | 339 | Protein_5 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EJC48_RS00040 () | 4704..5407 | + | 704 | Protein_6 | IS6 family transposase IS26 | Transposase |
| EJC48_RS00045 () | 5468..6304 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| EJC48_RS00050 () | 6304..7107 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| EJC48_RS00055 () | 7168..7983 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| EJC48_RS00065 () | 8291..9142 | - | 852 | WP_000240536.1 | replication protein | - |
| EJC48_RS00070 () | 9129..9848 | - | 720 | Protein_11 | AAA family ATPase | - |
| EJC48_RS00080 () | 9898..10602 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EJC48_RS00085 () | 10639..11766 | - | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| EJC48_RS00090 () | 11817..12044 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| EJC48_RS00095 () | 12068..12259 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| EJC48_RS00100 () | 12741..13283 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| EJC48_RS00105 () | 13296..14156 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| EJC48_RS00115 () | 14299..15261 | + | 963 | Protein_18 | IS4 family transposase IS10R | Transposase |
| EJC48_RS00120 () | 15371..16276 | + | 906 | Protein_19 | IS4 family transposase IS10R | Transposase |
| EJC48_RS00125 () | 16325..17029 | - | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EJC48_RS26375 () | 17093..17239 | + | 147 | Protein_21 | Tn3 family transposase TnpR_Tn3 | Transposase |
| EJC48_RS00135 () | 17422..18282 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| EJC48_RS00140 () | 18432..18530 | - | 99 | Protein_23 | IS1 family transposase | - |
| EJC48_RS00145 () | 18559..19869 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| EJC48_RS00150 () | 20154..20555 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| EJC48_RS00155 () | 20488..20745 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EJC48_RS00160 () | 20838..21491 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| EJC48_RS26125 () | 21589..21729 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| EJC48_RS00170 () | 22430..23287 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| EJC48_RS00175 () | 23280..23354 | - | 75 | WP_014966221.1 | RepA leader peptide Tap | - |
| EJC48_RS26380 () | 23351..23485 | - | 135 | Protein_31 | protein CopA/IncA | - |
| EJC48_RS00185 () | 23716..25257 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| EJC48_RS00190 () | 25272..26002 | + | 731 | Protein_33 | IS21 family transposase ISEc12 | Transposase |
| EJC48_RS00195 () | 26162..26416 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| EJC48_RS00200 () | 26713..26847 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 26892..26952 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 26892..26952 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 26892..26952 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 26892..26952 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| EJC48_RS26130 () | 26919..27205 | - | 287 | Protein_36 | DUF2726 domain-containing protein | - |
| EJC48_RS00215 () | 27718..27930 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| EJC48_RS00220 () | 28061..28621 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| EJC48_RS00225 () | 28676..29422 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| EJC48_RS00230 () | 29442..34712 | - | 5271 | WP_048237267.1 | Multifunctional conjugation protein TraI | Relaxase |
| EJC48_RS00235 () | 34712..36910 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| EJC48_RS00240 () | 36907..37686 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| EJC48_RS00245 () | 37889..38620 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| EJC48_RS00250 () | 38652..39149 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| EJC48_RS00255 () | 39168..41987 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| EJC48_RS00260 () | 41984..43357 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| EJC48_RS00265 () | 43344..43769 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| EJC48_RS00270 () | 43717..44064 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| EJC48_RS00275 () | 43994..44539 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EJC48_RS00280 () | 44526..44810 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| EJC48_RS00285 () | 44937..45257 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| EJC48_RS00290 () | 45305..46002 | - | 698 | Protein_52 | IS1 family transposase IS1G | Transposase |
| EJC48_RS00295 () | 46157..46930 | - | 774 | Protein_53 | IS5 family transposase ISKpn26 | Transposase |
| EJC48_RS00300 () | 47013..47417 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| EJC48_RS00305 () | 47414..47761 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| EJC48_RS00310 () | 47810..49345 | + | 1536 | WP_001333339.1 | IS66 family transposase ISEc22 | Transposase |
| EJC48_RS00315 () | 49388..49600 | - | 213 | Protein_57 | IS5/IS1182 family transposase | - |
| EJC48_RS00320 () | 49730..50473 | - | 744 | WP_001030401.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EJC48_RS00325 () | 50466..50723 | - | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| EJC48_RS00330 () | 50750..52600 | - | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EJC48_RS00335 () | 52597..53235 | - | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EJC48_RS00340 () | 53244..53549 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| EJC48_RS00345 () | 53579..54571 | - | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| EJC48_RS00350 () | 54568..55200 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| EJC48_RS00355 () | 55197..55583 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| EJC48_RS00360 () | 55580..58207 | - | 2628 | WP_001064258.1 | type IV secretion system protein TraC | - |
| EJC48_RS00365 () | 58367..58588 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| EJC48_RS00370 () | 58723..59238 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EJC48_RS00375 () | 59238..59597 | - | 360 | WP_001617876.1 | conjugal transfer protein TrbD | - |
| EJC48_RS00380 () | 59536..60123 | - | 588 | WP_071587349.1 | conjugal transfer protein TraP | - |
| EJC48_RS00385 () | 60092..61543 | - | 1452 | WP_000146687.1 | conjugal transfer protein TraB | - |
| EJC48_RS00390 () | 61543..62247 | - | 705 | WP_148725207.1 | type-F conjugative transfer system secretin TraK | - |
| EJC48_RS00395 () | 62258..62824 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| EJC48_RS00400 () | 62846..63157 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| EJC48_RS00405 () | 63162..63524 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| EJC48_RS00410 () | 63558..63785 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| EJC48_RS00415 () | 63873..64550 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| EJC48_RS00420 () | 64684..65067 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| EJC48_RS00425 () | 65398..66000 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| EJC48_RS00430 () | 66297..67118 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| EJC48_RS00435 () | 67237..67524 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| EJC48_RS00440 () | 67775..68755 | + | 981 | WP_032154316.1 | IS110 family transposase IS1663 | Transposase |
| EJC48_RS26385 () | 68941..69132 | - | 192 | Protein_83 | single-stranded DNA-binding protein | - |
| EJC48_RS00460 () | 69823..69981 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 70025..70063 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 70025..70063 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 70025..70063 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 70025..70063 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - () | 71503..71605 | - | 103 | NuclAT_0 | - | - |
| - () | 71503..71605 | - | 103 | NuclAT_0 | - | - |
| - () | 71503..71605 | - | 103 | NuclAT_0 | - | - |
| - () | 71503..71605 | - | 103 | NuclAT_0 | - | - |
| EJC48_RS00470 () | 71617..72336 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| EJC48_RS00475 () | 72333..72767 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| EJC48_RS00480 () | 72822..74780 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| EJC48_RS00485 () | 74846..75079 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| EJC48_RS00490 () | 75142..75681 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| EJC48_RS00495 () | 75933..76913 | + | 981 | WP_032154316.1 | IS110 family transposase IS1663 | Transposase |
| EJC48_RS00520 () | 77702..77915 | - | 214 | Protein_92 | hypothetical protein | - |
| EJC48_RS00525 () | 77941..78504 | - | 564 | WP_129483993.1 | class I SAM-dependent methyltransferase | - |
| EJC48_RS00530 () | 78551..79912 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| EJC48_RS00535 () | 79964..80194 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| EJC48_RS00545 () | 81229..81420 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| EJC48_RS00550 () | 81417..81839 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| EJC48_RS00555 () | 81886..82188 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| EJC48_RS00565 () | 82728..83504 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| EJC48_RS00570 () | 83555..83989 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| EJC48_RS00575 () | 84003..84224 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| EJC48_RS00580 () | 84225..84908 | - | 684 | WP_000086185.1 | DNA methylase | - |
| EJC48_RS00585 () | 84985..85289 | - | 305 | Protein_103 | hypothetical protein | - |
| EJC48_RS00590 () | 85293..86195 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| EJC48_RS00605 () | 87062..88033 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| EJC48_RS00610 () | 88033..89199 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| EJC48_RS00615 () | 89787..90542 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| EJC48_RS00620 () | 91316..92121 | - | 806 | Protein_108 | IS91 family transposase ISSod25 | Transposase |
| EJC48_RS00625 () | 92122..92427 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| EJC48_RS00630 () | 92429..92647 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| EJC48_RS00635 () | 93281..93478 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| EJC48_RS00640 () | 93475..93759 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| EJC48_RS00645 () | 93779..94912 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| EJC48_RS00650 () | 95175..98294 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| EJC48_RS00660 () | 98601..98831 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| EJC48_RS00665 () | 98828..99244 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| EJC48_RS00670 () | 99406..101544 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| EJC48_RS00675 () | 102009..103004 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| EJC48_RS00680 () | 103008..103940 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| EJC48_RS00685 () | 104077..104774 | - | 698 | Protein_120 | IS1 family transposase IS1G | Transposase |
| EJC48_RS00690 () | 104988..108104 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| EJC48_RS00695 () | 108226..109509 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| EJC48_RS00700 () | 109506..111062 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| EJC48_RS00705 () | 111245..111466 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EJC48_RS00710 () | 111466..111846 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| EJC48_RS00715 () | 111851..112030 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| EJC48_RS00720 () | 112058..112417 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| EJC48_RS00725 () | 112341..112754 | + | 414 | Protein_128 | IS3 family transposase ISLad1 | Transposase |
| EJC48_RS00735 () | 113550..114527 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| EJC48_RS00740 () | 114812..115552 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| EJC48_RS00745 () | 115673..115855 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| EJC48_RS00755 () | 116198..116505 | - | 308 | Protein_132 | type II toxin-antitoxin system ParD family antitoxin | - |
| EJC48_RS00765 () | 116998..118167 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| EJC48_RS00770 () | 118200..118328 | + | 129 | Protein_134 | IS481 family transposase | - |
| EJC48_RS00775 () | 118363..118557 | - | 195 | WP_086258557.1 | hypothetical protein | - |
| EJC48_RS00780 () | 118599..119296 | + | 698 | Protein_136 | IS1 family transposase IS1R | Transposase |
| EJC48_RS00785 () | 119303..119824 | + | 522 | Protein_137 | IS4 family transposase IS10R | Transposase |
| EJC48_RS00790 () | 119834..120205 | - | 372 | WP_035689358.1 | Transposon Tn10 TetD protein | VF |
| EJC48_RS00795 () | 120338..120931 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| EJC48_RS00800 () | 121044..122249 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| EJC48_RS00805 () | 122331..122954 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| EJC48_RS00810 () | 122932..123051 | - | 120 | Protein_142 | ArsR family transcriptional regulator | - |
| EJC48_RS00815 () | 123067..123764 | - | 698 | Protein_143 | IS1 family transposase IS1R | Transposase |
| EJC48_RS00820 () | 123928..124632 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| EJC48_RS00825 () | 124686..124931 | - | 246 | Protein_145 | NAD(+)--rifampin ADP-ribosyltransferase | - |
| EJC48_RS00830 () | 125016..125648 | - | 633 | WP_000186237.1 | Chloramphenicol acetyltransferase | VF |
| EJC48_RS00835 () | 125786..126616 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| EJC48_RS00840 () | 126747..127301 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| EJC48_RS00845 () | 127445..128149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EJC48_RS00850 () | 128214..128894 | - | 681 | Protein_150 | IS91 family transposase ISAzo26 | Transposase |
| EJC48_RS00855 () | 129052..129525 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| EJC48_RS00860 () | 129656..130444 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| EJC48_RS00865 () | 130650..130999 | + | 350 | Protein_153 | QacE family quaternary ammonium compound efflux SMR transporter | - |
| EJC48_RS00870 () | 130993..131580 | + | 588 | Protein_154 | dihydropteroate synthase | - |
| EJC48_RS00875 () | 131646..132350 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| EJC48_RS00885 () | 132479..133243 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| EJC48_RS00900 () | 133736..134320 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|