MGE detailed information

MGE type: Conjugative plasmid        MGE length: 197872 bp
Accession: NZ_CP027054        Location: 1..197872         Organism: Klebsiella pneumoniae strain 2_GR_12       Replicon: plasmid IncFIB IncFII


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6D68_RS27620 () 16..222 + 207 WP_129557129.1 EAL domain-containing protein -
A6D68_RS27625 () 251..478 - 228 Protein_1 IS66 family transposase -
A6D68_RS27630 () 553..846 - 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
A6D68_RS27635 () 945..1712 - 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
A6D68_RS27640 () 1713..2669 - 957 WP_004152281.1 Fe(3+) dicitrate transport system permease protein FecD VF
A6D68_RS27645 () 2666..3664 - 999 WP_004118243.1 Fe(3+) dicitrate transport system permease protein FecC VF
A6D68_RS27650 () 3661..4563 - 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
A6D68_RS27655 () 4608..6932 - 2325 WP_004152280.1 Fe(3+) dicitrate transport protein FecA -
A6D68_RS27660 () 7018..7971 - 954 WP_004118237.1 fec operon regulator FecR -
A6D68_RS27665 () 7968..8489 - 522 WP_004118235.1 putative RNA polymerase sigma factor FecI VF
A6D68_RS27670 () 8965..9450 - 486 Protein_10 IS21 family transposase ISEc62 Transposase
A6D68_RS32110 () 9451..9663 - 213 WP_161989521.1 hypothetical protein -
A6D68_RS27675 () 9592..9759 + 168 WP_004118231.1 integrase -
A6D68_RS27680 () 10044..11171 + 1128 WP_004118840.1 transporter substrate-binding protein -
A6D68_RS27685 () 11168..11761 + 594 WP_004118229.1 ANTAR domain-containing protein -
A6D68_RS27690 () 11758..12606 + 849 WP_004152279.1 ABC transporter permease -
A6D68_RS27695 () 12606..13526 + 921 WP_004118227.1 ABC transporter permease -
A6D68_RS27700 () 13539..15143 + 1605 WP_004152278.1 ABC transporter substrate-binding protein -
A6D68_RS27705 () 15188..16135 + 948 WP_004118225.1 acetamidase/formamidase family protein -
A6D68_RS27710 () 16143..17876 + 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
A6D68_RS27715 () 19697..20074 - 378 Protein_20 IS66 family transposase ISEc22 Transposase
A6D68_RS27720 () 20112..21649 - 1538 Protein_21 IS66 family transposase ISCfr14 Transposase
A6D68_RS27725 () 21699..22046 - 348 WP_004152557.1 IS66 family transposase ISCfr14 Transposase
A6D68_RS27730 () 22043..22429 - 387 WP_020956879.1 IS66 family transposase ISSgsp1 Transposase
A6D68_RS27735 () 22977..23612 - 636 WP_004118217.1 His-Xaa-Ser repeat protein HxsA -
A6D68_RS27740 () 23609..24721 - 1113 WP_000005560.1 His-Xaa-Ser system radical SAM maturase HxsC -
A6D68_RS27745 () 24714..26102 - 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
A6D68_RS27750 () 26102..26341 - 240 WP_176716597.1 His-Xaa-Ser system protein HxsD -
A6D68_RS27755 () 26334..27031 - 698 Protein_28 IS1 family transposase IS1R Transposase
A6D68_RS27765 () 27310..27969 + 660 WP_000412211.1 Chloramphenicol acetyltransferase ARG
A6D68_RS27770 () 28170..28547 - 378 WP_000656305.1 GNAT family N-acetyltransferase -
A6D68_RS27775 () 28614..31580 - 2967 WP_032422421.1 Tn3 family transposase TnpA_TnAs3 Transposase
A6D68_RS27780 () 31583..32143 - 561 WP_000147567.1 Tn3 family transposase TnpR_TnAs3 Transposase
A6D68_RS27785 () 32269..32619 - 351 WP_000454193.1 DUF3330 domain-containing protein -
A6D68_RS27795 () 32822..33835 - 1014 WP_000845039.1 IS91 family transposase ISAzo26 Transposase
A6D68_RS27800 () 33980..34477 + 498 WP_001083725.1 Dihydrofolate reductase ARG
A6D68_RS27805 () 34589..34879 + 291 WP_001336345.1 DUF1010 domain-containing protein -
A6D68_RS27810 () 34885..35676 + 792 WP_001206356.1 Streptomycin 3''-adenylyltransferase ARG
A6D68_RS27815 () 35840..36187 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
A6D68_RS27820 () 36181..37020 + 840 WP_000259031.1 Dihydropteroate synthase ARG
A6D68_RS27830 () 37148..37351 + 204 WP_000376616.1 hypothetical protein -
A6D68_RS27835 () 37507..38712 + 1206 WP_000184001.1 chromate efflux transporter -
A6D68_RS27840 () 38723..39028 + 306 WP_000130000.1 hypothetical protein Relaxase
A6D68_RS32115 () 39072..39137 + 66 Protein_43 EAL domain-containing protein -
A6D68_RS27850 () 39255..40019 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
A6D68_RS27865 () 40512..41096 - 585 WP_001137892.1 TetR family transcriptional regulator -
A6D68_RS27870 () 41096..42334 - 1239 WP_000004159.1 MFS transporter -
A6D68_RS27875 () 42331..43236 - 906 WP_000219391.1 hypothetical protein ARG
A6D68_RS27885 () 43358..44062 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
A6D68_RS27890 () 44213..45028 + 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
A6D68_RS27895 () 45212..45503 + 292 Protein_50 transposase -
A6D68_RS27905 () 46085..47065 - 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
A6D68_RS27910 () 47324..48021 - 698 Protein_52 IS1 family transposase IS1X3 Transposase
A6D68_RS27915 () 48206..48322 - 117 Protein_53 transposase domain-containing protein -
A6D68_RS32120 () 48267..48530 - 264 WP_004118209.1 transposase -
A6D68_RS32125 () 48545..48808 + 264 WP_004118208.1 hypothetical protein -
A6D68_RS27925 () 49052..49333 + 282 WP_004152118.1 helix-turn-helix domain-containing protein -
A6D68_RS27930 () 49368..49937 + 570 WP_004152117.1 Spore protein SP21 VF
A6D68_RS27935 () 50052..52847 + 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
A6D68_RS27940 () 52847..53044 + 198 WP_004152115.1 hypothetical protein -
A6D68_RS27950 () 53282..54031 + 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
A6D68_RS27955 () 54018..54980 + 963 WP_004152113.1 M48 family metalloprotease -
A6D68_RS27960 () 55068..56322 + 1255 Protein_62 IS3 family transposase ISKpn38 Transposase
A6D68_RS27965 () 56823..58169 - 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
A6D68_RS27970 () 58381..58863 - 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
A6D68_RS27975 () 58851..59117 - 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
A6D68_RS27980 () 59293..59547 - 255 WP_004152108.1 hypothetical protein -
A6D68_RS27985 () 59623..59880 - 258 WP_004152107.1 hypothetical protein -
A6D68_RS27990 () 59929..60132 - 204 WP_004152106.1 hemolysin expression modulator Hha -
A6D68_RS27995 () 60166..60534 - 369 WP_004152105.1 hypothetical protein -
A6D68_RS28000 () 60578..61072 - 495 WP_004152104.1 DNA-binding protein -
A6D68_RS28005 () 61103..61678 - 576 WP_004152103.1 hypothetical protein -
A6D68_RS28010 () 61666..61935 - 270 WP_004152102.1 hypothetical protein -
A6D68_RS28015 () 62293..62643 + 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
A6D68_RS28020 () 62693..63055 + 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
A6D68_RS28025 () 63073..64824 + 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
A6D68_RS28030 () 64872..66161 + 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
A6D68_RS28035 () 66174..66599 + 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
A6D68_RS28040 () 66632..67168 - 537 WP_004152096.1 GNAT family N-acetyltransferase -
A6D68_RS28045 () 67290..69040 - 1751 Protein_79 arsenical pump-driving ATPase -
A6D68_RS28050 () 69065..69427 - 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
A6D68_RS28055 () 69503..70048 - 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
A6D68_RS28060 () 70057..70770 - 714 WP_004152093.1 arsenical resistance protein ArsH -
A6D68_RS28065 () 70767..71093 - 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
A6D68_RS28070 () 71425..71922 + 498 WP_004152091.1 GNAT family N-acetyltransferase -
A6D68_RS28075 () 71972..72481 - 510 WP_031944101.1 aquaporin -
A6D68_RS28080 () 72543..74163 + 1621 Protein_86 ISL3 family transposase -
A6D68_RS28085 () 74224..74403 + 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
A6D68_RS28090 () 74635..75069 - 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
A6D68_RS28095 () 75286..76686 - 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
A6D68_RS28100 () 76683..77363 - 681 WP_001188930.1 Transcriptional activator protein CopR VF
A6D68_RS28105 () 77418..78347 - 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
A6D68_RS28110 () 78352..78732 - 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
A6D68_RS28115 () 78772..79662 - 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
A6D68_RS28120 () 79668..81485 - 1818 WP_004152083.1 multicopper oxidase PcoA -
A6D68_RS28125 () 81719..82168 + 450 WP_001023257.1 copper resistance protein -
A6D68_RS28130 () 82457..83194 + 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
A6D68_RS28135 () 83228..83425 - 198 WP_000843497.1 DUF2933 domain-containing protein -
A6D68_RS28140 () 83466..85913 - 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
A6D68_RS28145 () 86040..86480 - 441 WP_000758228.1 hypothetical protein -
A6D68_RS28150 () 86567..89713 - 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
A6D68_RS28155 () 89724..91016 - 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
A6D68_RS28160 () 91130..91483 - 354 WP_001246153.1 cation efflux system protein CusF -
A6D68_RS28165 () 91512..92897 - 1386 WP_000475512.1 Cation efflux system protein CusC VF
A6D68_RS28170 () 93087..93767 + 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
A6D68_RS28175 () 93760..95235 + 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
A6D68_RS28180 () 95486..95917 + 432 WP_004178091.1 silver-binding protein SilE -
A6D68_RS28185 () 96213..96755 - 543 Protein_107 ISL3 family transposase ISKpn25 Transposase
A6D68_RS28190 () 96771..97255 - 485 Protein_108 IS1 family transposase IS1X2 Transposase
A6D68_RS28195 () 97346..98553 + 1208 WP_085955172.1 IS3 family transposase ISEcl1 Transposase
A6D68_RS28200 () 98744..99441 + 698 Protein_110 IS1 family transposase IS1X2 Transposase
A6D68_RS28205 () 99593..101590 + 1998 WP_004178088.1 choline BCCT transporter BetT -
A6D68_RS28210 () 101653..102930 + 1278 WP_004152070.1 DUF2254 domain-containing protein -
A6D68_RS28215 () 103913..105367 - 1455 WP_020444838.1 putative cyclic di-GMP phosphodiesterase PdeB VF
A6D68_RS28220 () 105969..106226 + 258 WP_004197688.1 hypothetical protein -
A6D68_RS28225 () 106899..107867 - 969 WP_011977741.1 IS5 family transposase IS903B Transposase
A6D68_RS28235 () 107887..108198 + 312 WP_071527918.1 EAL domain-containing protein -
A6D68_RS28240 () 108225..109172 - 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
A6D68_RS28245 () 110316..111056 + 741 WP_001515717.1 tyrosine-type recombinase/integrase -
A6D68_RS28255 () 111773..112783 - 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
A6D68_RS28260 () 113535..114701 + 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF
A6D68_RS28265 () 114701..115672 + 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
A6D68_RS28280 () 117109..118307 + 1199 Protein_122 IS200-IS605 family transposase IS609 Transposase
A6D68_RS28285 () 118330..118545 - 216 Protein_123 type II toxin-antitoxin system Phd/YefM family antitoxin -
A6D68_RS28290 () 118624..119895 - 1272 WP_004152715.1 Y-family DNA polymerase -
A6D68_RS28295 () 119895..120320 - 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
A6D68_RS28305 () 120723..122210 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
A6D68_RS28310 () 122444..122674 + 231 WP_004152753.1 hypothetical protein -
A6D68_RS28320 () 123195..123620 + 426 WP_004118478.1 antirestriction protein -
A6D68_RS28325 () 123857..124111 + 255 WP_004152754.1 DNA polymerase III subunit theta -
A6D68_RS28330 () 124146..124463 + 318 WP_004118473.1 hypothetical protein -
A6D68_RS28340 () 125245..125472 + 228 WP_004178072.1 hypothetical protein -
A6D68_RS28345 () 125564..125794 + 231 WP_004198570.1 hypothetical protein -
A6D68_RS28350 () 125846..127201 + 1356 WP_032418010.1 DUF3560 domain-containing protein -
A6D68_RS28355 () 127249..127812 + 564 WP_004152645.1 methyltransferase -
A6D68_RS28370 () 128588..129130 + 543 WP_004152644.1 single-stranded DNA-binding protein -
A6D68_RS28375 () 129179..129427 + 249 WP_004152643.1 DUF905 domain-containing protein -
A6D68_RS28380 () 129497..131533 + 2037 WP_032422417.1 ParB/RepB/Spo0J family partition protein -
A6D68_RS28385 () 131600..132031 + 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
A6D68_RS28390 () 132028..132756 + 729 WP_004152640.1 plasmid SOS inhibition protein A -
A6D68_RS28395 () 132753..133079 + 327 WP_004199358.1 hypothetical protein -
A6D68_RS28400 () 133135..133509 + 375 WP_004152638.1 hypothetical protein -
A6D68_RS28410 () 133687..134766 - 1080 WP_004220208.1 IS481 family transposase ISKpn28 Transposase
A6D68_RS28415 () 134838..134999 + 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
A6D68_RS28420 () 135699..135971 + 273 WP_004152759.1 hypothetical protein -
A6D68_RS28425 () 135968..136318 + 351 WP_004152758.1 hypothetical protein -
A6D68_RS28435 () 136954..137310 + 357 WP_032422418.1 hypothetical protein -
A6D68_RS28440 () 137371..137583 + 213 WP_004152718.1 hypothetical protein -
A6D68_RS28445 () 137594..137818 + 225 WP_004152719.1 hypothetical protein -
A6D68_RS28450 () 137899..138219 + 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
A6D68_RS28455 () 138209..138487 + 279 WP_004152721.1 helix-turn-helix domain-containing protein -
A6D68_RS28460 () 138488..138901 + 414 WP_004152722.1 helix-turn-helix domain-containing protein -
A6D68_RS28480 () 139735..140556 + 822 WP_004178064.1 DUF945 domain-containing protein -
A6D68_RS28485 () 140589..140918 + 330 WP_011977736.1 hypothetical protein -
A6D68_RS28490 () 140951..141436 - 486 WP_004178063.1 hypothetical protein VF
A6D68_RS28495 () 141870..142262 + 393 WP_004178062.1 relaxosome protein TraM -
A6D68_RS28500 () 142485..143171 + 687 WP_011977735.1 transcriptional regulator TraJ family protein -
A6D68_RS28505 () 143255..143626 + 372 WP_004208838.1 TraY domain-containing protein -
A6D68_RS28510 () 143680..144048 + 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
A6D68_RS28515 () 144062..144367 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
A6D68_RS28520 () 144387..144953 + 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
A6D68_RS28525 () 144940..145680 + 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
A6D68_RS28530 () 145680..147104 + 1425 WP_004152600.1 conjugal transfer protein TraB -
A6D68_RS28535 () 147097..147693 + 597 WP_004152599.1 conjugal transfer protein TraP -
A6D68_RS28540 () 147716..148285 + 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
A6D68_RS28545 () 148417..148827 + 411 WP_004152597.1 lipase chaperone -
A6D68_RS28550 () 148832..149122 + 291 WP_004152596.1 hypothetical protein -
A6D68_RS28555 () 149146..149364 + 219 WP_004171484.1 hypothetical protein -
A6D68_RS28560 () 149365..149682 + 318 WP_004152595.1 hypothetical protein -
A6D68_RS28565 () 149749..150153 + 405 WP_004152594.1 hypothetical protein -
A6D68_RS28575 () 150449..150847 + 399 WP_004153071.1 hypothetical protein -
A6D68_RS28580 () 150919..153558 + 2640 WP_004152592.1 type IV secretion system protein TraC -
A6D68_RS28585 () 153558..153947 + 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
A6D68_RS28590 () 153947..154573 + 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
A6D68_RS28595 () 154584..155576 + 993 WP_004178057.1 conjugal transfer pilus assembly protein TraU -
A6D68_RS28600 () 155589..156227 + 639 WP_004152672.1 type-F conjugative transfer system pilin assembly protein TrbC -
A6D68_RS28605 () 156275..158230 + 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
A6D68_RS28610 () 158262..158498 + 237 WP_004152683.1 conjugal transfer protein TrbE -
A6D68_RS28620 () 158726..159052 + 327 WP_004152685.1 hypothetical protein -
A6D68_RS28625 () 159073..159825 + 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
A6D68_RS28630 () 159836..160075 + 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
A6D68_RS28635 () 160047..160619 + 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
A6D68_RS28640 () 160612..161040 + 429 WP_004152689.1 hypothetical protein -
A6D68_RS28645 () 161027..162397 + 1371 WP_004159274.1 conjugal transfer protein TraH -
A6D68_RS28650 () 162397..165246 + 2850 WP_004242672.1 conjugal transfer mating pair stabilization protein TraG -
A6D68_RS28655 () 165259..165807 + 549 WP_004152623.1 conjugal transfer entry exclusion protein TraS -
A6D68_RS28660 () 165991..166722 + 732 WP_004152622.1 complement resistance protein TraT -
A6D68_RS32175 () 166914..167603 + 690 WP_004198206.1 hypothetical protein -
A6D68_RS28670 () 167732..170044 + 2313 Protein_188 type IV conjugative transfer system coupling protein TraD -
A6D68_RS28675 () 170044..175305 + 5262 WP_004153015.1 Multifunctional conjugation protein TraI Relaxase
A6D68_RS28680 () 175386..176111 + 726 WP_004152379.1 type-F conjugative transfer system pilin acetylase TraX -
A6D68_RS28685 () 176183..176776 + 594 WP_004152380.1 fertility inhibition protein FinO -
A6D68_RS28690 () 176937..177539 + 603 WP_015060010.1 hypothetical protein -
A6D68_RS28695 () 177589..178233 + 645 WP_004153014.1 hypothetical protein -
A6D68_RS28700 () 178289..178939 + 651 WP_004152382.1 DUF2726 domain-containing protein -
A6D68_RS28705 () 178936..179244 + 309 WP_004152383.1 hypothetical protein -
A6D68_RS28710 () 179420..179899 + 480 WP_014343478.1 Phospholipase D VF
A6D68_RS28715 () 180017..180286 + 270 WP_013609506.1 replication regulatory protein RepA -
A6D68_RS28720 () 180518..180595 + 78 WP_004171450.1 RepA leader peptide Tap -
A6D68_RS28725 () 180588..181445 + 858 WP_004152386.1 incFII family plasmid replication initiator RepA -
A6D68_RS28740 () 182892..185087 - 2196 WP_000093087.1 DEAD/DEAH box helicase -
A6D68_RS28745 () 185084..186400 - 1317 WP_004152291.1 ATP-binding protein -
A6D68_RS28750 () 186404..188713 - 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
A6D68_RS28755 () 189358..190327 - 970 Protein_203 IS5 family transposase IS903B Transposase
A6D68_RS28760 () 190419..191672 - 1254 WP_003846917.1 lactose permease -
A6D68_RS28765 () 191724..194798 - 3075 WP_004152287.1 beta-galactosidase -
A6D68_RS28770 () 194920..196002 - 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
A6D68_RS28780 () 196463..197473 + 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance