MGE detailed information

MGE type: Conjugative plasmid        MGE length: 211813 bp
Accession: NZ_CP026752        Location: 1..211813         Organism: Klebsiella pneumoniae strain AR_0066       Replicon: plasmid tig00000080_pilon


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM445_RS27260 () 273..1283 + 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
AM445_RS27265 () 1687..2691 + 1005 WP_000427619.1 IS110-like element IS5075 family transposase -
AM445_RS27270 () 2989..3231 + 243 WP_071527925.1 EAL domain-containing protein -
AM445_RS27275 () 3260..3487 - 228 Protein_3 IS66 family transposase -
AM445_RS27280 () 3562..3855 - 294 WP_004118251.1 IS66 family insertion sequence element accessory protein TnpB -
AM445_RS27285 () 3954..4721 - 768 WP_004152282.1 Fe(3+) dicitrate ABC transporter ATP-binding protein FecE -
AM445_RS27290 () 4722..5678 - 957 WP_004152281.1 Fe(3+) dicitrate ABC transporter permease subunit FecD -
AM445_RS27295 () 5675..6673 - 999 WP_004118243.1 iron-dicitrate ABC transporter permease FecC -
AM445_RS27300 () 6670..7572 - 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
AM445_RS27305 () 7617..9941 - 2325 WP_004152280.1 Fe(3+) dicitrate transport protein FecA -
AM445_RS27310 () 10027..10980 - 954 WP_004118237.1 fec operon regulator FecR -
AM445_RS27315 () 10977..11498 - 522 WP_004118235.1 RNA polymerase sigma factor FecI -
AM445_RS27325 () 11974..12459 - 486 Protein_12 transposase -
AM445_RS29680 () 12460..12672 - 213 WP_161989521.1 hypothetical protein -
AM445_RS27330 () 12601..12768 + 168 WP_004118231.1 integrase -
AM445_RS27335 () 13053..14180 + 1128 WP_004118840.1 transporter substrate-binding protein -
AM445_RS27340 () 14177..14770 + 594 WP_004118229.1 ANTAR domain-containing protein -
AM445_RS27345 () 14767..15615 + 849 WP_004152279.1 ABC transporter permease -
AM445_RS27350 () 15615..16535 + 921 WP_004118227.1 ABC transporter permease -
AM445_RS27355 () 16548..18152 + 1605 WP_004152278.1 ABC transporter substrate-binding protein -
AM445_RS27360 () 18197..19144 + 948 WP_004118225.1 acetamidase/formamidase family protein -
AM445_RS27365 () 19152..20885 + 1734 WP_004118832.1 ABC transporter ATP-binding protein -
AM445_RS27370 () 21936..22633 - 698 Protein_22 IS1 family transposase -
AM445_RS27385 () 22912..23571 + 660 WP_000412211.1 type A-1 chloramphenicol O-acetyltransferase -
AM445_RS27390 () 23772..24149 - 378 WP_000656305.1 GNAT family N-acetyltransferase -
AM445_RS27395 () 24460..25464 - 1005 WP_000427623.1 IS110-like element IS4321 family transposase -
AM445_RS27400 () 25543..28509 - 2967 WP_001138064.1 Tn3-like element TnAs3 family transposase -
AM445_RS27405 () 28512..28667 - 156 Protein_27 Hin recombinase -
AM445_RS27410 () 28732..29436 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
AM445_RS27415 () 29642..29950 - 309 Protein_29 IS5/IS1182 family transposase -
AM445_RS27420 () 30292..31119 + 828 WP_004153729.1 phosphonate ABC transporter ATP-binding protein -
AM445_RS27425 () 31116..31979 + 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
AM445_RS27430 () 31988..32815 + 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
AM445_RS27435 () 32824..33834 + 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
AM445_RS27440 () 33828..34697 + 870 WP_004152692.1 LysR family transcriptional regulator -
AM445_RS27445 () 34805..35324 + 520 Protein_35 IS5-like element ISPst7 family transposase -
AM445_RS27460 () 35906..36886 - 981 WP_000019473.1 IS5-like element ISKpn26 family transposase -
AM445_RS27465 () 37145..37842 - 698 Protein_37 IS1 family transposase -
AM445_RS27470 () 38027..38143 - 117 Protein_38 transposase domain-containing protein -
AM445_RS29145 () 38088..38351 - 264 WP_004118209.1 transposase -
AM445_RS29150 () 38366..38629 + 264 WP_004118208.1 hypothetical protein -
AM445_RS27480 () 38873..39154 + 282 WP_004152118.1 helix-turn-helix domain-containing protein -
AM445_RS27485 () 39189..39758 + 570 WP_004152117.1 small heat shock protein sHSP20 -
AM445_RS27490 () 39873..42668 + 2796 WP_004152116.1 heat shock survival AAA family ATPase ClpK -
AM445_RS27495 () 42668..42865 + 198 WP_004152115.1 hypothetical protein -
AM445_RS27505 () 43103..43852 + 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
AM445_RS27510 () 43839..44801 + 963 WP_004152113.1 M48 family metalloprotease -
AM445_RS27515 () 44889..46143 + 1255 Protein_47 IS3 family transposase -
AM445_RS27520 () 46644..47990 - 1347 WP_020314316.1 ISNCY family transposase -
AM445_RS27525 () 48202..48684 - 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
AM445_RS27530 () 48672..48938 - 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
AM445_RS27535 () 49114..49368 - 255 WP_004152108.1 hypothetical protein -
AM445_RS27540 () 49444..49701 - 258 WP_004152107.1 hypothetical protein -
AM445_RS27545 () 49750..49953 - 204 WP_004152106.1 hemolysin expression modulator Hha -
AM445_RS27550 () 49987..50355 - 369 WP_004152105.1 hypothetical protein -
AM445_RS27555 () 50399..50893 - 495 WP_004152104.1 DNA-binding protein -
AM445_RS27560 () 50924..51499 - 576 WP_004152103.1 hypothetical protein -
AM445_RS27565 () 51487..51756 - 270 WP_004152102.1 hypothetical protein -
AM445_RS27570 () 52114..52464 + 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
AM445_RS27575 () 52514..52876 + 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
AM445_RS27580 () 52894..54645 + 1752 WP_004152099.1 arsenite efflux transporter ATPase subunit ArsA -
AM445_RS27585 () 54693..55982 + 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
AM445_RS27590 () 55995..56420 + 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
AM445_RS27595 () 56453..56989 - 537 WP_004152096.1 GNAT family N-acetyltransferase -
AM445_RS27600 () 57111..58861 - 1751 Protein_64 arsenical pump-driving ATPase -
AM445_RS27605 () 58886..59248 - 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
AM445_RS27610 () 59324..59869 - 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
AM445_RS27615 () 59878..60591 - 714 WP_004152093.1 arsenical resistance protein ArsH -
AM445_RS27620 () 60588..60914 - 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
AM445_RS27625 () 61246..61743 + 498 WP_004152091.1 GNAT family N-acetyltransferase -
AM445_RS27630 () 61793..62302 - 510 WP_031944101.1 aquaporin -
AM445_RS27635 () 62364..63984 + 1621 Protein_71 ISL3 family transposase -
AM445_RS27640 () 64045..64224 + 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
AM445_RS27645 () 64456..64890 - 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
AM445_RS27650 () 65107..65271 - 165 Protein_74 two-component sensor histidine kinase -
AM445_RS27655 () 65358..65783 + 426 WP_000422741.1 IS66 family insertion sequence hypothetical protein -
AM445_RS27660 () 65780..66130 + 351 WP_000624722.1 IS66 family insertion sequence element accessory protein TnpB -
AM445_RS27665 () 66161..67774 + 1614 WP_000080200.1 IS66-like element ISEc23 family transposase -
AM445_RS27670 () 67761..69047 - 1287 WP_072280712.1 sensor histidine kinase -
AM445_RS27675 () 69044..69724 - 681 WP_001188930.1 copper response regulator transcription factor PcoR -
AM445_RS27680 () 69779..70708 - 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
AM445_RS27685 () 70713..71093 - 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
AM445_RS27690 () 71133..72023 - 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
AM445_RS27695 () 72029..73846 - 1818 WP_000925242.1 multicopper oxidase PcoA -
AM445_RS27700 () 74080..74529 + 450 WP_001023257.1 copper resistance protein -
AM445_RS27705 () 74818..75555 + 738 WP_004118669.1 peptidoglycan DD-metalloendopeptidase family protein -
AM445_RS27710 () 75589..75786 - 198 WP_000843497.1 DUF2933 domain-containing protein -
AM445_RS27715 () 75827..78274 - 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
AM445_RS27720 () 78401..78841 - 441 WP_000758228.1 hypothetical protein -
AM445_RS27725 () 78928..82074 - 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
AM445_RS27730 () 82085..83377 - 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
AM445_RS27735 () 83491..83844 - 354 WP_001246153.1 cation efflux system protein CusF -
AM445_RS27740 () 83873..85258 - 1386 WP_000475512.1 Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC -
AM445_RS27745 () 85448..86128 + 681 WP_001572351.1 copper/silver response regulator transcription factor SilR -
AM445_RS27750 () 86121..87596 + 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
AM445_RS27755 () 87847..88278 + 432 WP_004178091.1 silver-binding protein SilE -
AM445_RS27760 () 88574..88840 - 267 Protein_96 ISL3 family transposase -
AM445_RS27765 () 88924..89328 + 405 WP_003031976.1 IS66 family insertion sequence hypothetical protein -
AM445_RS27770 () 89325..89672 + 348 WP_000612626.1 IS66 family insertion sequence element accessory protein TnpB -
AM445_RS27775 () 89721..91259 + 1539 WP_004201219.1 IS66-like element ISKpn24 family transposase -
AM445_RS27780 () 91297..91578 - 282 Protein_100 transposase -
AM445_RS27785 () 91594..92078 - 485 Protein_101 IS1 family transposase -
AM445_RS27790 () 92169..93376 + 1208 WP_085955172.1 IS3 family transposase -
AM445_RS27800 () 93567..94264 + 698 Protein_103 IS1 family transposase -
AM445_RS27805 () 94416..96413 + 1998 WP_004178088.1 choline BCCT transporter BetT -
AM445_RS27810 () 96476..97753 + 1278 WP_004152070.1 DUF2254 domain-containing protein -
AM445_RS27815 () 98736..100190 - 1455 WP_071890189.1 EAL domain-containing protein -
AM445_RS27820 () 100792..101049 + 258 WP_004197688.1 hypothetical protein -
AM445_RS27825 () 101722..102690 - 969 WP_011977741.1 IS5 family transposase -
AM445_RS27835 () 102710..103021 + 312 WP_071527918.1 EAL domain-containing protein -
AM445_RS27840 () 103048..103995 - 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
AM445_RS27845 () 105139..105879 + 741 WP_001515717.1 tyrosine-type recombinase/integrase -
AM445_RS27855 () 106596..107606 - 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
AM445_RS27860 () 108358..109524 + 1167 WP_000523813.1 plasmid-partitioning protein SopA -
AM445_RS27865 () 109524..110495 + 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
AM445_RS27880 () 111932..113130 + 1199 Protein_115 transposase -
AM445_RS27885 () 113153..113368 - 216 Protein_116 type II toxin-antitoxin system Phd/YefM family antitoxin -
AM445_RS27890 () 113447..114718 - 1272 WP_004152715.1 Y-family DNA polymerase -
AM445_RS27895 () 114718..115143 - 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
AM445_RS27905 () 115546..117033 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
AM445_RS27910 () 117267..117497 + 231 WP_004152753.1 hypothetical protein -
AM445_RS27925 () 118018..118443 + 426 WP_004118478.1 antirestriction protein -
AM445_RS27930 () 118680..118934 + 255 WP_004152754.1 DNA polymerase III subunit theta -
AM445_RS27935 () 118969..119286 + 318 WP_004118473.1 hypothetical protein -
AM445_RS27945 () 120068..120295 + 228 WP_004178072.1 hypothetical protein -
AM445_RS27950 () 120387..120617 + 231 WP_004198570.1 hypothetical protein -
AM445_RS27955 () 120669..122024 + 1356 WP_004178068.1 DUF3560 domain-containing protein -
AM445_RS27960 () 122072..122635 + 564 WP_004152645.1 methyltransferase -
AM445_RS27975 () 123411..123953 + 543 WP_043907040.1 single-stranded DNA-binding protein -
AM445_RS27980 () 124002..124250 + 249 WP_004152643.1 DUF905 domain-containing protein -
AM445_RS27985 () 124320..126356 + 2037 Protein_130 ParB/RepB/Spo0J family partition protein -
AM445_RS27990 () 126423..126854 + 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
AM445_RS27995 () 126851..127579 + 729 WP_004152640.1 plasmid SOS inhibition protein A -
AM445_RS28000 () 127576..127902 + 327 WP_004152639.1 hypothetical protein -
AM445_RS28005 () 127958..128332 + 375 WP_004152638.1 hypothetical protein -
AM445_RS28015 () 128510..129589 - 1080 WP_004220208.1 IS481-like element ISKpn28 family transposase -
AM445_RS28020 () 129661..129822 + 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
AM445_RS28025 () 130522..130794 + 273 WP_004152759.1 hypothetical protein -
AM445_RS28030 () 130791..131141 + 351 WP_004152758.1 hypothetical protein -
AM445_RS28040 () 131777..132133 + 357 WP_004152717.1 hypothetical protein -
AM445_RS28045 () 132194..132406 + 213 WP_004152718.1 hypothetical protein -
AM445_RS28050 () 132417..132641 + 225 WP_004152719.1 hypothetical protein -
AM445_RS28055 () 132722..133042 + 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
AM445_RS28060 () 133032..133310 + 279 WP_004152721.1 helix-turn-helix domain-containing protein -
AM445_RS28065 () 133311..133724 + 414 WP_004152722.1 helix-turn-helix domain-containing protein -
AM445_RS28085 () 134558..135379 + 822 WP_004178064.1 DUF945 domain-containing protein -
AM445_RS28090 () 135412..135741 + 330 WP_011977736.1 hypothetical protein -
AM445_RS28095 () 135774..136259 - 486 WP_004178063.1 transglycosylase SLT domain-containing protein -
AM445_RS28100 () 136693..137085 + 393 WP_004178062.1 relaxosome protein TraM -
AM445_RS28105 () 137308..137994 + 687 WP_011977735.1 transcriptional regulator TraJ family protein -
AM445_RS28110 () 138078..138449 + 372 WP_004208838.1 TraY domain-containing protein -
AM445_RS28115 () 138503..138871 + 369 WP_004152496.1 type IV conjugative transfer system pilin TraA -
AM445_RS28120 () 138885..139190 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
AM445_RS28125 () 139210..139776 + 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
AM445_RS28130 () 139763..140503 + 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
AM445_RS28135 () 140503..141927 + 1425 WP_004152600.1 conjugal transfer protein TraB -
AM445_RS28140 () 141920..142516 + 597 WP_004152599.1 conjugal transfer protein TraP -
AM445_RS28145 () 142539..143108 + 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
AM445_RS28150 () 143240..143650 + 411 WP_004152597.1 lipase chaperone -
AM445_RS28155 () 143655..143945 + 291 WP_004152596.1 hypothetical protein -
AM445_RS28160 () 143969..144187 + 219 WP_004171484.1 hypothetical protein -
AM445_RS28165 () 144188..144505 + 318 WP_004152595.1 hypothetical protein -
AM445_RS28170 () 144572..144976 + 405 WP_004152594.1 hypothetical protein -
AM445_RS28180 () 145272..145670 + 399 WP_004153071.1 hypothetical protein -
AM445_RS28185 () 145742..148381 + 2640 WP_004152592.1 type IV secretion system protein TraC -
AM445_RS28190 () 148381..148759 + 379 Protein_165 type-F conjugative transfer system protein TrbI -
AM445_RS28195 () 148759..149385 + 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
AM445_RS28200 () 149396..150388 + 993 WP_004178057.1 conjugal transfer pilus assembly protein TraU -
AM445_RS28205 () 150401..151039 + 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
AM445_RS28210 () 151087..153042 + 1956 WP_040145764.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
AM445_RS28215 () 153074..153328 + 255 WP_004152674.1 conjugal transfer protein TrbE -
AM445_RS28220 () 153306..153554 + 249 WP_013214029.1 hypothetical protein -
AM445_RS28225 () 153567..153893 + 327 WP_013214030.1 hypothetical protein -
AM445_RS28230 () 153914..154666 + 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
AM445_RS28235 () 154677..154916 + 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
AM445_RS28240 () 154888..155445 + 558 WP_013214031.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
AM445_RS28245 () 155491..155934 + 444 WP_030003485.1 F-type conjugal transfer protein TrbF -
AM445_RS28250 () 155912..157291 + 1380 WP_011977731.1 conjugal transfer protein TraH -
AM445_RS28255 () 157291..160140 + 2850 WP_004152624.1 conjugal transfer mating pair stabilization protein TraG -
AM445_RS28260 () 160153..160701 + 549 WP_004152623.1 conjugal transfer entry exclusion protein TraS -
AM445_RS28265 () 160885..161616 + 732 WP_004152622.1 complement resistance protein TraT -
AM445_RS29685 () 161808..162497 + 690 WP_004198206.1 hypothetical protein -
AM445_RS28275 () 162626..164938 + 2313 Protein_182 type IV conjugative transfer system coupling protein TraD -
AM445_RS28280 () 164938..170196 + 5259 WP_043907038.1 conjugative transfer relaxase/helicase TraI -
AM445_RS28285 () 170277..171002 + 726 WP_013214040.1 type-F conjugative transfer system pilin acetylase TraX -
AM445_RS28290 () 171074..171667 + 594 WP_004152380.1 fertility inhibition protein FinO -
AM445_RS28295 () 171828..172430 + 603 WP_015060010.1 hypothetical protein -
AM445_RS28300 () 172562..173259 + 698 Protein_187 IS1 family transposase -
AM445_RS28305 () 173563..175086 + 1524 WP_013214042.1 type I restriction-modification system subunit M -
AM445_RS28310 () 175076..176350 + 1275 WP_013214043.1 restriction endonuclease subunit S -
AM445_RS28315 () 176347..177030 + 684 WP_001459731.1 YecA family protein -
AM445_RS28320 () 177083..180367 + 3285 WP_013214044.1 type I restriction endonuclease subunit R -
AM445_RS28325 () 180364..181119 + 756 WP_009310009.1 M48 family metallopeptidase -
AM445_RS28335 () 181206..181391 + 186 Protein_193 IS1 family transposase -
AM445_RS28340 () 181390..181629 + 240 Protein_194 IS110 family transposase -
AM445_RS28345 () 181646..181954 + 309 Protein_195 DDE-type integrase/transposase/recombinase -
AM445_RS28350 () 181979..183430 + 1452 WP_000443938.1 DUF262 domain-containing protein -
AM445_RS28355 () 183423..185465 + 2043 WP_013214046.1 DUF262 domain-containing HNH endonuclease family protein -
AM445_RS28360 () 185652..191387 + 5736 WP_021314612.1 DUF4011 domain-containing protein -
AM445_RS28365 () 191608..191763 - 156 Protein_199 IS3 family transposase -
AM445_RS28370 () 191841..192245 + 405 WP_003031976.1 IS66 family insertion sequence hypothetical protein -
AM445_RS28375 () 192242..192589 + 348 WP_000612626.1 IS66 family insertion sequence element accessory protein TnpB -
AM445_RS28380 () 192638..194176 + 1539 WP_004201219.1 IS66-like element ISKpn24 family transposase -
AM445_RS28385 () 194289..194546 + 258 WP_099459485.1 bacteriocin immunity protein -
AM445_RS28390 () 194848..195327 + 480 WP_064762441.1 phospholipase D family protein -
AM445_RS28395 () 195647..195925 + 279 WP_004099069.1 replication regulatory protein RepA -
AM445_RS28400 () 196141..196218 + 78 WP_014386216.1 RepA leader peptide Tap -
AM445_RS28405 () 196211..197068 + 858 WP_013213997.1 incFII family plasmid replication initiator RepA -
AM445_RS28420 () 198515..200710 - 2196 WP_000093087.1 DEAD/DEAH box helicase -
AM445_RS28425 () 200707..202023 - 1317 WP_004152291.1 ATP-binding protein -
AM445_RS28430 () 202027..204336 - 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
AM445_RS28435 () 204981..205950 - 970 Protein_211 IS5-like element IS903B family transposase -
AM445_RS28440 () 206042..207295 - 1254 WP_050885149.1 lactose permease -
AM445_RS28445 () 207347..210421 - 3075 WP_004152287.1 beta-galactosidase -
AM445_RS28450 () 210543..211625 - 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance