MGE detailed information

MGE type: Conjugative plasmid        MGE length: 215872 bp
Accession: NZ_CP025577        Location: 1..215872         Organism: Klebsiella pneumoniae strain 08EU827       Replicon: plasmid p08EU827_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CY656_RS26015 () 135..1148 + 1014 WP_016831068.1 hypothetical protein -
CY656_RS26025 () 2540..4735 - 2196 WP_071005035.1 DEAD/DEAH box helicase -
CY656_RS26030 () 4732..6048 - 1317 WP_004152291.1 ATP-binding protein -
CY656_RS26035 () 6052..8361 - 2310 WP_071005031.1 TerB N-terminal domain-containing protein -
CY656_RS26040 () 8977..9945 - 969 WP_068814619.1 IS5 family transposase IS903B Transposase
CY656_RS26045 () 9983..10234 - 252 WP_071005090.1 DUF1471 domain-containing protein -
CY656_RS26050 () 10360..11151 - 792 WP_071005088.1 SDR family oxidoreductase -
CY656_RS26055 () 11300..12193 + 894 WP_071005086.1 HTH-type transcriptional regulator PgrR VF
CY656_RS26060 () 12228..13217 - 990 WP_071005084.1 aldo/keto reductase -
CY656_RS26065 () 13244..14095 - 852 WP_071005081.1 aldo/keto reductase -
CY656_RS26070 () 14565..15632 - 1068 WP_071005079.1 SMEK domain-containing protein -
CY656_RS26075 () 15863..16927 - 1065 WP_071005077.1 alpha/beta fold hydrolase -
CY656_RS26080 () 17035..17619 - 585 WP_071005075.1 flavodoxin -
CY656_RS26085 () 17629..18390 - 762 WP_071005073.1 carboxymuconolactone decarboxylase family protein -
CY656_RS26090 () 18368..18847 - 480 WP_071005071.1 cupin domain-containing protein -
CY656_RS26095 () 18912..20369 - 1458 WP_071005091.1 heavy metal sensor histidine kinase -
CY656_RS26100 () 20385..21065 - 681 WP_071005069.1 Transcriptional activator protein CzcR VF
CY656_RS26105 () 21080..22246 - 1167 WP_175441005.1 aldo/keto reductase -
CY656_RS26110 () 22497..23546 + 1050 WP_021571251.1 alpha/beta hydrolase -
CY656_RS26115 () 23806..24486 + 681 WP_071005065.1 nitroreductase -
CY656_RS26120 () 24494..25696 - 1203 WP_070083055.1 multidrug effflux MFS transporter -
CY656_RS26125 () 26279..26509 - 231 WP_029498498.1 hypothetical protein -
CY656_RS26130 () 26523..26696 - 174 WP_071996522.1 hypothetical protein -
CY656_RS26135 () 26697..27077 + 381 Protein_23 EAL domain-containing protein -
CY656_RS26140 () 27259..28263 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
CY656_RS26145 () 28850..29932 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
CY656_RS26150 () 30054..33128 + 3075 WP_029498501.1 beta-galactosidase -
CY656_RS26155 () 33180..34433 + 1254 WP_023158026.1 lactose permease -
CY656_RS26160 () 34499..34639 + 141 Protein_28 galactoside O-acetyltransferase -
CY656_RS26165 () 34654..35349 - 696 Protein_29 IS1 family transposase IS1S Transposase
CY656_RS26170 () 35442..35808 + 367 Protein_30 Tn3 family transposase TnpA_ISSba14 Transposase
CY656_RS26175 () 35887..36891 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
CY656_RS26180 () 37189..37431 + 243 WP_071785586.1 EAL domain-containing protein -
CY656_RS26185 () 37460..37687 - 228 Protein_33 IS66 family transposase -
CY656_RS26190 () 37762..38055 - 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
CY656_RS26195 () 38154..38921 - 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
CY656_RS26200 () 38922..39878 - 957 WP_047670035.1 Fe(3+) dicitrate transport system permease protein FecD VF
CY656_RS26205 () 39875..40873 - 999 WP_004118243.1 Fe(3+) dicitrate transport system permease protein FecC VF
CY656_RS26210 () 40870..41772 - 903 WP_023157913.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
CY656_RS26215 () 41817..44141 - 2325 WP_029498502.1 Fe(3+) dicitrate transport protein FecA -
CY656_RS26220 () 44234..45187 - 954 WP_004197067.1 fec operon regulator FecR -
CY656_RS26225 () 45184..45705 - 522 WP_004197062.1 putative RNA polymerase sigma factor FecI VF
CY656_RS26230 () 46181..46666 - 486 Protein_42 IS21 family transposase ISEc62 Transposase
CY656_RS26235 () 46808..46975 + 168 WP_004118231.1 integrase -
CY656_RS26240 () 47260..48387 + 1128 WP_004118840.1 transporter substrate-binding protein -
CY656_RS26245 () 48384..48977 + 594 WP_004118229.1 ANTAR domain-containing protein -
CY656_RS26250 () 48974..49822 + 849 WP_004118228.1 ABC transporter permease -
CY656_RS26255 () 49822..50742 + 921 WP_004118227.1 ABC transporter permease -
CY656_RS26260 () 50755..52359 + 1605 WP_004152278.1 ABC transporter substrate-binding protein -
CY656_RS26265 () 52404..53351 + 948 WP_004118225.1 acetamidase/formamidase family protein -
CY656_RS26270 () 53359..55092 + 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
CY656_RS26275 () 55268..55704 + 437 Protein_51 creatininase family protein -
CY656_RS26290 () 56333..56870 + 538 Protein_52 DUF2913 family protein -
CY656_RS26295 () 57052..58056 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
CY656_RS26300 () 58330..59298 + 969 WP_072143344.1 IS5 family transposase IS903B Transposase
CY656_RS26305 () 59355..59734 + 380 Protein_55 transposase family protein -
CY656_RS26310 () 59778..60242 - 465 Protein_56 IS91 family transposase IS1294 Transposase
CY656_RS26315 () 60294..61214 - 921 WP_004181990.1 putative cyclic di-GMP phosphodiesterase VF
CY656_RS26320 () 61177..64557 - 3381 WP_004181991.1 Aerobic respiration control sensor protein ArcB VF
CY656_RS26325 () 64862..66052 + 1191 WP_004197507.1 urea ABC transporter substrate-binding protein -
CY656_RS26330 () 66109..67035 + 927 WP_004181993.1 urea ABC transporter permease subunit UrtB -
CY656_RS26335 () 67045..68160 + 1116 WP_004181994.1 urea ABC transporter permease subunit UrtC -
CY656_RS26340 () 68157..68906 + 750 WP_004181995.1 urea ABC transporter ATP-binding protein UrtD -
CY656_RS26345 () 68917..69606 + 690 WP_080882234.1 urea ABC transporter ATP-binding subunit UrtE -
CY656_RS26350 () 69642..70649 + 1008 WP_004181997.1 formamidase -
CY656_RS26355 () 70857..71554 - 698 Protein_65 IS1 family transposase IS1X3 Transposase
CY656_RS26360 () 71739..71855 - 117 Protein_66 transposase domain-containing protein -
CY656_RS28745 () 71800..72063 - 264 WP_004118209.1 transposase -
CY656_RS28750 () 72078..72341 + 264 WP_004118208.1 hypothetical protein -
CY656_RS26370 () 72585..72866 + 282 WP_004152118.1 helix-turn-helix domain-containing protein -
CY656_RS26375 () 72901..73470 + 570 WP_004152117.1 Spore protein SP21 VF
CY656_RS26380 () 73603..76398 + 2796 WP_048255129.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
CY656_RS26385 () 76398..76595 + 198 WP_004152115.1 hypothetical protein -
CY656_RS26395 () 76833..77582 + 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
CY656_RS26400 () 77569..78531 + 963 WP_004152113.1 M48 family metalloprotease -
CY656_RS26405 () 78619..79873 + 1255 Protein_75 IS3 family transposase ISKpn38 Transposase
CY656_RS26410 () 80032..80181 - 150 Protein_76 GNAT family N-acetyltransferase -
CY656_RS26415 () 80204..80707 - 504 Protein_77 Tn3 family transposase TnpA_TnEc1 Transposase
CY656_RS26420 () 80772..81476 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CY656_RS26425 () 81840..83315 - 1476 WP_020324153.1 SEC-C domain-containing protein -
CY656_RS26440 () 85017..85247 - 231 Protein_80 replication initiation protein -
CY656_RS26445 () 85300..86004 - 705 Protein_81 IS6 family transposase IS26 Transposase
CY656_RS26450 () 86069..86437 + 369 Protein_82 Tn3 family transposase TnpR_ISSba14 Transposase
CY656_RS26455 () 86624..87181 + 558 WP_032445547.1 OsmC family protein -
CY656_RS26460 () 87323..87904 + 582 WP_008502230.1 HTH-type transcriptional repressor NemR VF
CY656_RS26465 () 87909..88247 + 339 WP_000888080.1 carboxymuconolactone decarboxylase family protein -
CY656_RS26470 () 88277..88606 - 330 WP_008502229.1 thioredoxin family protein -
CY656_RS26475 () 88819..89925 + 1107 WP_006687059.1 alkene reductase -
CY656_RS26480 () 89991..90692 + 702 WP_008502228.1 DsbA family oxidoreductase -
CY656_RS26485 () 90758..91531 + 774 WP_001091224.1 SDR family oxidoreductase -
CY656_RS26490 () 91717..92940 - 1224 WP_000872613.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
CY656_RS26495 () 93071..93901 - 831 WP_020324597.1 DMT family transporter -
CY656_RS26500 () 94143..94895 + 753 WP_020324592.1 alpha/beta hydrolase -
CY656_RS26505 () 94922..95235 + 314 Protein_93 Tn3 family transposase -
CY656_RS26510 () 95310..95684 + 375 WP_000110555.1 arsenic transporter ATPase -
CY656_RS26515 () 95715..96140 - 426 WP_000065758.1 glutaredoxin-dependent arsenate reductase -
CY656_RS26520 () 96153..97442 - 1290 WP_000922630.1 arsenite efflux transporter membrane subunit ArsB -
CY656_RS26525 () 97491..99242 - 1752 WP_001556710.1 arsenite efflux transporter ATPase subunit ArsA -
CY656_RS26530 () 99260..99622 - 363 WP_020324593.1 arsenite efflux transporter metallochaperone ArsD -
CY656_RS26535 () 99670..100023 - 354 WP_001114073.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
CY656_RS28875 () 100339..100932 + 594 WP_044348674.1 hypothetical protein -
CY656_RS26550 () 101356..102015 + 660 WP_000078540.1 hypothetical protein -
CY656_RS26555 () 102012..102341 + 330 WP_004118613.1 hypothetical protein -
CY656_RS26560 () 102334..103536 + 1203 WP_003031541.1 hypothetical protein -
CY656_RS26565 () 103573..103992 - 420 WP_000990392.1 helix-turn-helix domain-containing protein Antitoxin Detail
CY656_RS26570 () 103989..104300 - 312 WP_004118600.1 type II toxin-antitoxin system HigB family toxin Toxin Detail
CY656_RS26575 () 104511..104891 + 381 Protein_106 gluconate permease -
CY656_RS26580 () 104941..105636 - 696 WP_004118595.1 lactate utilization protein C -
CY656_RS26585 () 105629..107056 - 1428 WP_000023895.1 iron-sulfur cluster-binding protein -
CY656_RS26590 () 107067..107786 - 720 WP_001102107.1 (Fe-S)-binding protein -
CY656_RS26595 () 107861..109558 - 1698 WP_020324177.1 D-lactate dehydrogenase -
CY656_RS26600 () 109994..111547 + 1554 WP_020324174.1 L-lactate permease -
CY656_RS26610 () 113239..113442 - 204 WP_004150739.1 hemolysin expression modulator Hha -
CY656_RS26615 () 113503..113997 - 495 WP_004213594.1 hypothetical protein -
CY656_RS26620 () 114028..114594 - 567 WP_009310052.1 hypothetical protein -
CY656_RS26625 () 114591..114854 - 264 WP_009310051.1 hypothetical protein -
CY656_RS26630 () 115167..115346 + 180 WP_004118349.1 type II toxin-antitoxin system ParD family antitoxin -
CY656_RS26635 () 115333..115431 + 99 WP_032445197.1 type II toxin-antitoxin system RelE/ParE family toxin -
CY656_RS26645 () 115810..116244 - 435 WP_004118347.1 hypothetical protein -
CY656_RS26650 () 116460..117860 - 1401 WP_002436614.1 copper resistance membrane spanning protein PcoS -
CY656_RS26655 () 117857..118537 - 681 WP_001188930.1 Transcriptional activator protein CopR VF
CY656_RS26660 () 118592..119521 - 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
CY656_RS26665 () 119526..119906 - 381 WP_001549790.1 copper resistance system metallochaperone PcoC -
CY656_RS26670 () 119946..120836 - 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
CY656_RS26675 () 120842..122659 - 1818 WP_000925242.1 multicopper oxidase PcoA -
CY656_RS26680 () 122893..123342 + 450 WP_001023257.1 copper resistance protein -
CY656_RS26685 () 123631..124368 + 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
CY656_RS26690 () 124402..124599 - 198 WP_000843497.1 DUF2933 domain-containing protein -
CY656_RS26695 () 124640..127087 - 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
CY656_RS26700 () 127214..127654 - 441 WP_000758228.1 hypothetical protein -
CY656_RS26705 () 127741..130887 - 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
CY656_RS26710 () 130898..132190 - 1293 WP_004098959.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
CY656_RS26715 () 132304..132657 - 354 WP_001246153.1 cation efflux system protein CusF -
CY656_RS26720 () 132686..134071 - 1386 WP_000475512.1 Cation efflux system protein CusC VF
CY656_RS26725 () 134261..134941 + 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
CY656_RS26730 () 134934..136409 + 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
CY656_RS26735 () 136660..137091 + 432 WP_004178091.1 silver-binding protein SilE -
CY656_RS26740 () 137387..137929 - 543 Protein_138 ISL3 family transposase ISKpn25 Transposase
CY656_RS26745 () 137945..138429 - 485 Protein_139 IS1 family transposase IS1X2 Transposase
CY656_RS26750 () 138520..139727 + 1208 WP_087530333.1 IS3 family transposase ISEcl1 Transposase
CY656_RS26755 () 139918..140615 + 698 Protein_141 IS1 family transposase IS1X2 Transposase
CY656_RS26760 () 140767..142764 + 1998 WP_004178088.1 choline BCCT transporter BetT -
CY656_RS26765 () 142827..144104 + 1278 WP_004152070.1 DUF2254 domain-containing protein -
CY656_RS26770 () 145087..146523 - 1437 WP_080895248.1 putative cyclic di-GMP phosphodiesterase PdeB VF
CY656_RS26775 () 147143..147400 + 258 WP_004197688.1 hypothetical protein -
CY656_RS26780 () 148073..149041 - 969 WP_068814619.1 IS5 family transposase IS903B Transposase
CY656_RS26790 () 149061..149372 + 312 WP_071527918.1 EAL domain-containing protein -
CY656_RS26795 () 149399..150346 - 948 WP_004182028.1 sensor domain-containing diguanylate cyclase -
CY656_RS26800 () 151490..152230 + 741 WP_020324066.1 tyrosine-type recombinase/integrase -
CY656_RS26805 () 152948..153958 - 1011 WP_004182030.1 RepB family plasmid replication initiator protein -
CY656_RS26810 () 154710..155876 + 1167 WP_004182032.1 Sporulation initiation inhibitor protein Soj VF
CY656_RS26815 () 155876..156847 + 972 WP_004182039.1 ParB/RepB/Spo0J family plasmid partition protein -
CY656_RS26825 () 157890..159009 + 1120 Protein_153 IS3 family transposase ISSen4 Transposase
CY656_RS26830 () 159784..160479 - 696 Protein_154 IS1 family transposase IS1A Transposase
CY656_RS26840 () 161447..162727 + 1281 WP_004182042.1 DUF262 domain-containing protein -
CY656_RS26845 () 162724..164676 + 1953 WP_000037308.1 DUF262 domain-containing HNH endonuclease family protein -
CY656_RS26850 () 164921..165172 - 252 WP_004182043.1 hypothetical protein -
CY656_RS26855 () 165251..166522 - 1272 WP_023157784.1 Y-family DNA polymerase -
CY656_RS26860 () 166522..166947 - 426 WP_004182047.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
CY656_RS26870 () 167349..168884 + 1536 WP_164849034.1 group II intron reverse transcriptase/maturase -
CY656_RS26875 () 169118..169348 + 231 WP_004118481.1 hypothetical protein -
CY656_RS26885 () 169868..170293 + 426 WP_004118478.1 antirestriction protein -
CY656_RS26890 () 170530..170784 + 255 WP_004152754.1 DNA polymerase III subunit theta -
CY656_RS26895 () 170819..171136 + 318 WP_004118473.1 hypothetical protein -
CY656_RS26900 () 171863..172090 + 228 WP_004182050.1 hypothetical protein -
CY656_RS26905 () 172182..172412 + 231 WP_001568051.1 hypothetical protein -
CY656_RS26910 () 172464..173819 + 1356 WP_004182052.1 DUF3560 domain-containing protein -
CY656_RS26915 () 173867..174430 + 564 WP_004182054.1 methyltransferase -
CY656_RS26930 () 175258..176079 + 822 WP_004182076.1 DUF945 domain-containing protein -
CY656_RS26935 () 176112..176441 + 330 WP_011977736.1 hypothetical protein -
CY656_RS26940 () 176474..176959 - 486 WP_004178063.1 hypothetical protein VF
CY656_RS26945 () 177350..177766 + 417 WP_072145360.1 relaxosome protein TraM -
CY656_RS26950 () 177966..178685 + 720 WP_016831034.1 conjugal transfer protein TrbJ -
CY656_RS26955 () 178818..179024 + 207 WP_171773970.1 TraY domain-containing protein -
CY656_RS26960 () 179086..179454 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
CY656_RS26965 () 179468..179773 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
CY656_RS26970 () 179793..180359 + 567 WP_016831035.1 type IV conjugative transfer system protein TraE -
CY656_RS26975 () 180346..181086 + 741 WP_014386193.1 type-F conjugative transfer system secretin TraK -
CY656_RS26980 () 181086..182510 + 1425 WP_023158013.1 conjugal transfer protein TraB -
CY656_RS26985 () 182503..182682 + 180 WP_016831037.1 hypothetical protein -
CY656_RS26990 () 182692..183099 + 408 WP_108444198.1 hypothetical protein -
CY656_RS26995 () 183122..183706 + 585 WP_014386196.1 type IV conjugative transfer system lipoprotein TraV -
CY656_RS27000 () 183838..184261 + 424 Protein_183 hypothetical protein -
CY656_RS27005 () 184266..184555 + 290 Protein_184 hypothetical protein -
CY656_RS27010 () 184579..184797 + 219 WP_014386199.1 hypothetical protein -
CY656_RS27015 () 184798..185109 + 312 WP_071005063.1 hypothetical protein -
CY656_RS27020 () 185176..185580 + 405 WP_016831042.1 hypothetical protein -
CY656_RS27025 () 185623..186012 + 390 WP_023158009.1 hypothetical protein -
CY656_RS27030 () 186020..186418 + 399 WP_023158008.1 hypothetical protein -
CY656_RS27035 () 186490..189129 + 2640 WP_071005061.1 type IV secretion system protein TraC -
CY656_RS27040 () 189129..189518 + 390 WP_004167468.1 type-F conjugative transfer system protein TrbI -
CY656_RS27045 () 189518..190153 + 636 WP_020325113.1 type-F conjugative transfer system protein TraW -
CY656_RS27050 () 190188..190589 + 402 WP_023158005.1 hypothetical protein -
CY656_RS27055 () 190586..191575 + 990 WP_015632509.1 conjugal transfer pilus assembly protein TraU -
CY656_RS28775 () 191596..191772 + 177 WP_162866177.1 hypothetical protein -
CY656_RS27060 () 191851..192498 + 648 WP_015632510.1 type-F conjugative transfer system pilin assembly protein TrbC -
CY656_RS27065 () 192557..194512 + 1956 WP_101963440.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CY656_RS27070 () 194544..194798 + 255 WP_015065558.1 conjugal transfer protein TrbE -
CY656_RS27075 () 194776..195024 + 249 WP_004152675.1 hypothetical protein -
CY656_RS27080 () 195037..195363 + 327 WP_015065534.1 hypothetical protein -
CY656_RS27085 () 195384..196136 + 753 WP_015065535.1 type-F conjugative transfer system pilin assembly protein TraF -
CY656_RS27090 () 196147..196386 + 240 WP_023158003.1 type-F conjugative transfer system pilin chaperone TraQ -
CY656_RS27095 () 196358..196915 + 558 WP_023158002.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CY656_RS27100 () 196961..197404 + 444 WP_023158001.1 F-type conjugal transfer protein TrbF -
CY656_RS27105 () 197382..198761 + 1380 WP_023158000.1 conjugal transfer protein TraH -
CY656_RS27110 () 198761..201610 + 2850 WP_023329044.1 conjugal transfer mating pair stabilization protein TraG -
CY656_RS27115 () 201616..202143 + 528 WP_029498351.1 conjugal transfer protein TraS -
CY656_RS27120 () 202333..203064 + 732 WP_004152629.1 complement resistance protein TraT -
CY656_RS27125 () 203422..205704 + 2283 Protein_209 type IV conjugative transfer system coupling protein TraD -
CY656_RS27130 () 205704..210962 + 5259 WP_029498346.1 Multifunctional conjugation protein TraI Relaxase
CY656_RS27135 () 211043..211768 + 726 WP_016831060.1 type-F conjugative transfer system pilin acetylase TraX -
CY656_RS27140 () 211840..212436 + 597 WP_016831061.1 fertility inhibition protein FinO -
CY656_RS28880 () 212456..212803 + 348 Protein_213 hypothetical protein -
CY656_RS27150 () 213273..213494 + 222 WP_029497438.1 hypothetical protein -
CY656_RS27155 () 213550..214200 + 651 WP_029498344.1 DUF2726 domain-containing protein -
CY656_RS27160 () 214197..214505 + 309 WP_016831065.1 hypothetical protein -
CY656_RS27165 () 214681..215160 + 480 WP_069346050.1 Phospholipase D VF
CY656_RS27170 () 215296..215565 + 270 WP_016831067.1 replication regulatory protein RepA -
CY656_RS27175 () 215777..215848 + 72 WP_071786674.1 RepA leader peptide Tap -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance