MGE detailed information
MGE type: Conjugative plasmid MGE length: 149158 bp
Accession: NZ_CP025145 Location: 1..149158 Organism: Klebsiella pneumoniae strain NR5632 Replicon: plasmid NR5632_p2
Accession: NZ_CP025145 Location: 1..149158 Organism: Klebsiella pneumoniae strain NR5632 Replicon: plasmid NR5632_p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CXB25_RS28420 () | 2..112 | + | 111 | Protein_0 | ISL3 family transposase ISKpn25 | Transposase |
| CXB25_RS28425 () | 122..661 | - | 540 | Protein_1 | ISL3 family transposase ISKpn25 | Transposase |
| CXB25_RS28430 () | 677..1161 | - | 485 | Protein_2 | IS1 family transposase IS1X2 | Transposase |
| CXB25_RS28435 () | 1252..2459 | + | 1208 | WP_085955172.1 | IS3 family transposase ISEcl1 | Transposase |
| CXB25_RS28445 () | 2650..3347 | + | 698 | Protein_4 | IS1 family transposase IS1X2 | Transposase |
| CXB25_RS28450 () | 3499..5496 | + | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| CXB25_RS28455 () | 5559..6836 | + | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| CXB25_RS28460 () | 7819..9273 | - | 1455 | Protein_7 | putative cyclic di-GMP phosphodiesterase PdeC | VF |
| CXB25_RS28465 () | 9876..10133 | + | 258 | WP_004197688.1 | hypothetical protein | - |
| CXB25_RS28470 () | 10806..11774 | - | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| CXB25_RS28475 () | 11794..12105 | + | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| CXB25_RS28480 () | 12132..13079 | - | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| CXB25_RS28485 () | 14223..14963 | + | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| CXB25_RS28495 () | 15680..16690 | - | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| CXB25_RS28500 () | 17442..18608 | + | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
| CXB25_RS28505 () | 18608..19579 | + | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| CXB25_RS28520 () | 21016..22214 | + | 1199 | Protein_16 | IS200-IS605 family transposase IS609 | Transposase |
| CXB25_RS28525 () | 22237..22452 | - | 216 | Protein_17 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| CXB25_RS28530 () | 22531..23802 | - | 1272 | WP_101140106.1 | Y-family DNA polymerase | - |
| CXB25_RS28535 () | 23802..24227 | - | 426 | WP_004178083.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CXB25_RS28545 () | 24630..26117 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| CXB25_RS28550 () | 26351..26581 | + | 231 | WP_004152753.1 | hypothetical protein | - |
| CXB25_RS28560 () | 27102..27527 | + | 426 | WP_004118478.1 | antirestriction protein | - |
| CXB25_RS28565 () | 27764..28018 | + | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| CXB25_RS28570 () | 28053..28370 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| CXB25_RS28580 () | 29152..29379 | + | 228 | WP_004178072.1 | hypothetical protein | - |
| CXB25_RS28585 () | 29471..29701 | + | 231 | WP_004198570.1 | hypothetical protein | - |
| CXB25_RS28590 () | 29753..31108 | + | 1356 | WP_004178068.1 | DUF3560 domain-containing protein | - |
| CXB25_RS28595 () | 31156..31719 | + | 564 | WP_004152645.1 | methyltransferase | - |
| CXB25_RS28610 () | 32495..33037 | + | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| CXB25_RS28615 () | 33086..33334 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| CXB25_RS28620 () | 33404..35461 | + | 2058 | WP_023287107.1 | ParB/RepB/Spo0J family partition protein | - |
| CXB25_RS28625 () | 35506..35937 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| CXB25_RS28630 () | 35934..36662 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| CXB25_RS28635 () | 36659..36985 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| CXB25_RS28640 () | 37041..37415 | + | 375 | WP_023287106.1 | hypothetical protein | - |
| - () | 37475..37599 | + | 125 | NuclAT_0 | - | - |
| - () | 37475..37599 | + | 125 | NuclAT_0 | - | - |
| - () | 37475..37599 | + | 125 | NuclAT_0 | - | - |
| - () | 37475..37599 | + | 125 | NuclAT_0 | - | - |
| CXB25_RS28650 () | 37643..37801 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| CXB25_RS28655 () | 38495..38767 | + | 273 | WP_023287105.1 | hypothetical protein | - |
| CXB25_RS28660 () | 38764..39114 | + | 351 | WP_023287104.1 | hypothetical protein | - |
| CXB25_RS28675 () | 39746..40102 | + | 357 | WP_004152717.1 | hypothetical protein | - |
| CXB25_RS28680 () | 40163..40375 | + | 213 | WP_004152718.1 | hypothetical protein | - |
| CXB25_RS28685 () | 40386..40610 | + | 225 | WP_004152719.1 | hypothetical protein | - |
| CXB25_RS28690 () | 40691..41011 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CXB25_RS28695 () | 41001..41279 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| CXB25_RS28700 () | 41280..41693 | + | 414 | WP_023287139.1 | helix-turn-helix domain-containing protein | - |
| CXB25_RS28720 () | 42525..43346 | + | 822 | WP_023287138.1 | DUF945 domain-containing protein | - |
| CXB25_RS28725 () | 43379..43708 | + | 330 | WP_011977736.1 | hypothetical protein | - |
| CXB25_RS28730 () | 43741..44226 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| CXB25_RS28735 () | 44617..45033 | + | 417 | WP_014343494.1 | relaxosome protein TraM | - |
| CXB25_RS28740 () | 45233..45970 | + | 738 | WP_013214018.1 | conjugal transfer protein TrbJ | - |
| CXB25_RS28745 () | 46085..46291 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| CXB25_RS28750 () | 46353..46721 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| CXB25_RS28755 () | 46735..47040 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| CXB25_RS28760 () | 47060..47626 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| CXB25_RS28765 () | 47613..48353 | + | 741 | WP_013214019.1 | type-F conjugative transfer system secretin TraK | - |
| CXB25_RS28770 () | 48353..49777 | + | 1425 | WP_023287137.1 | conjugal transfer protein TraB | - |
| CXB25_RS28775 () | 49850..50434 | + | 585 | WP_023287136.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CXB25_RS28780 () | 50757..50975 | + | 219 | WP_004195468.1 | hypothetical protein | - |
| CXB25_RS28785 () | 50976..51287 | + | 312 | WP_023287135.1 | hypothetical protein | - |
| CXB25_RS28790 () | 51354..51758 | + | 405 | WP_004197817.1 | hypothetical protein | - |
| CXB25_RS28805 () | 52135..52533 | + | 399 | WP_014343490.1 | hypothetical protein | - |
| CXB25_RS28810 () | 52605..55244 | + | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| CXB25_RS28815 () | 55244..55633 | + | 390 | WP_013214025.1 | type-F conjugative transfer system protein TrbI | - |
| CXB25_RS28820 () | 55633..56268 | + | 636 | WP_013214026.1 | type-F conjugative transfer system protein TraW | - |
| CXB25_RS28825 () | 56303..56704 | + | 402 | WP_004194979.1 | hypothetical protein | - |
| CXB25_RS28830 () | 56701..57690 | + | 990 | WP_013214027.1 | conjugal transfer pilus assembly protein TraU | - |
| CXB25_RS28835 () | 57703..58341 | + | 639 | WP_004193871.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| CXB25_RS28840 () | 58400..60355 | + | 1956 | WP_023287134.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| CXB25_RS28845 () | 60387..60641 | + | 255 | WP_023287133.1 | conjugal transfer protein TrbE | - |
| CXB25_RS28850 () | 60619..60867 | + | 249 | WP_013214029.1 | hypothetical protein | - |
| CXB25_RS28855 () | 60880..61206 | + | 327 | WP_004152676.1 | hypothetical protein | - |
| CXB25_RS28860 () | 61227..61979 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| CXB25_RS28865 () | 61990..62229 | + | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| CXB25_RS28870 () | 62201..62758 | + | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| CXB25_RS28875 () | 62804..63247 | + | 444 | WP_023287131.1 | F-type conjugal transfer protein TrbF | - |
| CXB25_RS28880 () | 63225..64604 | + | 1380 | WP_072159474.1 | conjugal transfer protein TraH | - |
| CXB25_RS28885 () | 64604..67453 | + | 2850 | WP_023287129.1 | conjugal transfer mating pair stabilization protein TraG | - |
| CXB25_RS28890 () | 67459..67986 | + | 528 | WP_032409657.1 | conjugal transfer protein TraS | - |
| CXB25_RS28895 () | 68175..68321 | + | 147 | WP_004197893.1 | hypothetical protein | - |
| CXB25_RS28900 () | 68287..68496 | + | 210 | Protein_79 | complement resistance protein TraT | - |
| CXB25_RS28905 () | 68553..69521 | - | 969 | WP_101140107.1 | IS5 family transposase IS903B | Transposase |
| CXB25_RS28910 () | 69599..69970 | + | 372 | WP_023287125.1 | TraT complement resistance protein | - |
| CXB25_RS30120 () | 70163..70852 | + | 690 | WP_013023831.1 | hypothetical protein | - |
| CXB25_RS28920 () | 70979..73288 | + | 2310 | Protein_83 | type IV conjugative transfer system coupling protein TraD | - |
| CXB25_RS28925 () | 73288..78546 | + | 5259 | WP_023287123.1 | Multifunctional conjugation protein TraI | Relaxase |
| CXB25_RS28930 () | 78636..79361 | + | 726 | WP_009309882.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| CXB25_RS28935 () | 79516..80112 | + | 597 | WP_009309883.1 | fertility inhibition protein FinO | - |
| CXB25_RS28940 () | 80132..80479 | + | 348 | WP_009309884.1 | hypothetical protein | - |
| CXB25_RS28945 () | 80950..81594 | + | 645 | WP_009309885.1 | hypothetical protein | - |
| CXB25_RS28950 () | 81650..82300 | + | 651 | WP_009309886.1 | DUF2726 domain-containing protein | - |
| CXB25_RS28955 () | 82297..82608 | + | 312 | WP_009309887.1 | hypothetical protein | - |
| CXB25_RS28965 () | 83105..83437 | + | 333 | WP_001549890.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CXB25_RS28970 () | 83443..84156 | + | 714 | WP_025801347.1 | arsenical resistance protein ArsH | - |
| CXB25_RS28975 () | 84214..84642 | - | 429 | WP_001549888.1 | glutaredoxin-dependent arsenate reductase | - |
| CXB25_RS28980 () | 84692..85975 | - | 1284 | WP_001549887.1 | arsenic transporter | - |
| CXB25_RS28985 () | 86071..86424 | - | 354 | WP_001549886.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CXB25_RS28990 () | 86908..88386 | + | 1479 | WP_001549885.1 | SulP family inorganic anion transporter | - |
| CXB25_RS28995 () | 88405..89232 | + | 828 | WP_004118529.1 | universal stress protein | - |
| CXB25_RS29000 () | 89304..90500 | - | 1197 | WP_001549953.1 | MFS transporter | - |
| CXB25_RS29005 () | 91029..91403 | + | 375 | WP_004118534.1 | fluoride efflux transporter CrcB | - |
| CXB25_RS29010 () | 91678..92826 | + | 1149 | WP_011977829.1 | Na+/H+ antiporter NhaA | - |
| CXB25_RS29015 () | 93180..93512 | - | 333 | WP_004118538.1 | multidrug efflux SMR transporter | - |
| CXB25_RS29020 () | 93775..94479 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CXB25_RS29025 () | 94544..94731 | + | 188 | Protein_103 | IS3 family transposase ISEc36 | Transposase |
| CXB25_RS29030 () | 94785..95489 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CXB25_RS29035 () | 95695..96003 | - | 309 | Protein_105 | IS5 family transposase ISThi1 | Transposase |
| CXB25_RS29040 () | 96345..97172 | + | 828 | WP_004153729.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| CXB25_RS29045 () | 97169..98032 | + | 864 | WP_004152695.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| CXB25_RS29050 () | 98041..98868 | + | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| CXB25_RS29055 () | 98877..99887 | + | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| CXB25_RS29060 () | 99881..100750 | + | 870 | WP_004152692.1 | HTH-type transcriptional activator CmpR | VF |
| CXB25_RS29065 () | 100858..101377 | + | 520 | Protein_111 | IS5 family transposase ISPst7 | Transposase |
| CXB25_RS29080 () | 101959..102939 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| CXB25_RS29085 () | 103198..103895 | - | 698 | Protein_113 | IS1 family transposase IS1X2 | Transposase |
| CXB25_RS29090 () | 104080..104196 | - | 117 | Protein_114 | transposase domain-containing protein | - |
| CXB25_RS29580 () | 104141..104404 | - | 264 | WP_004118209.1 | IS66 family transposase ISPpu19 | Transposase |
| CXB25_RS29585 () | 104419..104682 | + | 264 | WP_004118208.1 | hypothetical protein | - |
| CXB25_RS29100 () | 104926..105207 | + | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| CXB25_RS29105 () | 105242..105811 | + | 570 | WP_004152117.1 | Spore protein SP21 | VF |
| CXB25_RS29110 () | 105926..108721 | + | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| CXB25_RS29115 () | 108721..108918 | + | 198 | WP_004152115.1 | hypothetical protein | - |
| CXB25_RS29125 () | 109156..109905 | + | 750 | WP_009483782.1 | phosphate-starvation-inducible PsiE family protein | - |
| CXB25_RS29130 () | 109892..110854 | + | 963 | WP_004152113.1 | M48 family metalloprotease | - |
| CXB25_RS29135 () | 110942..112196 | + | 1255 | Protein_123 | IS3 family transposase ISKpn38 | Transposase |
| CXB25_RS29140 () | 112697..114043 | - | 1347 | WP_020314316.1 | ISNCY family transposase ISLad2 | Transposase |
| CXB25_RS29145 () | 114255..114737 | - | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| CXB25_RS29150 () | 114725..114991 | - | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| CXB25_RS29155 () | 115167..115421 | - | 255 | WP_004152108.1 | hypothetical protein | - |
| CXB25_RS29160 () | 115497..115754 | - | 258 | WP_004152107.1 | hypothetical protein | - |
| CXB25_RS29165 () | 115803..116006 | - | 204 | WP_004152106.1 | hemolysin expression modulator Hha | - |
| CXB25_RS29170 () | 116040..116408 | - | 369 | WP_004152105.1 | hypothetical protein | - |
| CXB25_RS29175 () | 116452..116946 | - | 495 | WP_004152104.1 | DNA-binding protein | - |
| CXB25_RS29180 () | 116977..117552 | - | 576 | WP_004152103.1 | hypothetical protein | - |
| CXB25_RS29185 () | 117540..117809 | - | 270 | WP_004152102.1 | hypothetical protein | - |
| CXB25_RS29190 () | 118167..118517 | + | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| CXB25_RS29195 () | 118567..118929 | + | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| CXB25_RS29200 () | 118947..120698 | + | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| CXB25_RS29205 () | 120746..122035 | + | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| CXB25_RS29210 () | 122048..122473 | + | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| CXB25_RS29215 () | 122506..123042 | - | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| CXB25_RS29220 () | 123164..124914 | - | 1751 | Protein_140 | arsenical pump-driving ATPase | - |
| CXB25_RS29225 () | 124939..125301 | - | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| CXB25_RS29230 () | 125377..125922 | - | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| CXB25_RS29235 () | 125931..126644 | - | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| CXB25_RS29240 () | 126641..126967 | - | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CXB25_RS29245 () | 127299..127796 | + | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| CXB25_RS29250 () | 127846..128355 | - | 510 | WP_031944101.1 | aquaporin | - |
| CXB25_RS29255 () | 128417..130037 | + | 1621 | Protein_147 | ISL3 family transposase | - |
| CXB25_RS29260 () | 130098..130277 | + | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CXB25_RS29265 () | 130509..130943 | - | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| CXB25_RS29270 () | 131160..132560 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| CXB25_RS29275 () | 132557..133237 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| CXB25_RS29280 () | 133292..134221 | - | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| CXB25_RS29285 () | 134226..134606 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| CXB25_RS29290 () | 134646..135536 | - | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| CXB25_RS29295 () | 135542..137359 | - | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| CXB25_RS29300 () | 137593..138042 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| CXB25_RS29305 () | 138331..139068 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| CXB25_RS29310 () | 139102..139299 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| CXB25_RS29315 () | 139340..141787 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| CXB25_RS29320 () | 141914..142354 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| CXB25_RS29325 () | 142441..145587 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| CXB25_RS29330 () | 145598..146890 | - | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| CXB25_RS29335 () | 147004..147357 | - | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| CXB25_RS29340 () | 147386..148771 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| CXB25_RS29345 () | 148961..149041 | + | 81 | Protein_165 | DNA-binding response regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|