MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 129299 bp
Accession: NZ_CP024876 Location: 1..129299 Organism: Klebsiella pneumoniae strain NH25 Replicon: plasmid pNH25.2
Accession: NZ_CP024876 Location: 1..129299 Organism: Klebsiella pneumoniae strain NH25 Replicon: plasmid pNH25.2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CU111_RS28175 () | 167..514 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| CU111_RS28180 () | 631..1476 | - | 846 | WP_001749984.1 | Streptomycin 3''-adenylyltransferase | ARG |
| CU111_RS28185 () | 1657..2130 | - | 474 | WP_001749985.1 | Dihydrofolate reductase type 1 | ARG |
| CU111_RS28190 () | 2263..2715 | - | 453 | WP_001749986.1 | hypothetical protein | ARG |
| CU111_RS28195 () | 2812..3366 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| CU111_RS28200 () | 3658..4671 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| CU111_RS28210 () | 5146..5850 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CU111_RS28215 () | 5915..6169 | + | 255 | Protein_8 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| CU111_RS28220 () | 6227..6469 | + | 243 | WP_000844627.1 | transposase | - |
| CU111_RS28225 () | 6501..7151 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| CU111_RS28230 () | 7257..8456 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| CU111_RS28235 () | 8488..9372 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| CU111_RS28240 () | 9510..9917 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| CU111_RS28245 () | 9906..11657 | + | 1752 | Protein_14 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| CU111_RS28255 () | 11810..14605 | - | 2796 | Protein_15 | Tn3 family transposase TnpA_Tn3 | Transposase |
| CU111_RS28260 () | 14619..14951 | + | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| CU111_RS28265 () | 14998..15873 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| CU111_RS28275 () | 16221..17201 | - | 981 | WP_000019445.1 | IS5 family transposase ISKpn26 | Transposase |
| CU111_RS28280 () | 17272..17505 | - | 234 | Protein_19 | hypothetical protein | - |
| CU111_RS28285 () | 17666..18259 | - | 594 | WP_013609537.1 | fertility inhibition protein FinO | - |
| CU111_RS28290 () | 18331..19056 | - | 726 | WP_013023834.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| CU111_RS28295 () | 19137..24397 | - | 5261 | Protein_22 | Multifunctional conjugation protein TraI | Relaxase |
| CU111_RS28300 () | 24397..26709 | - | 2313 | Protein_23 | type IV conjugative transfer system coupling protein TraD | - |
| CU111_RS28305 () | 26836..27219 | - | 384 | WP_017900859.1 | hypothetical protein | - |
| CU111_RS28310 () | 27717..28448 | - | 732 | WP_013023830.1 | complement resistance protein TraT | - |
| CU111_RS28315 () | 28639..29166 | - | 528 | Protein_26 | conjugal transfer protein TraS | - |
| CU111_RS28320 () | 29169..32018 | - | 2850 | WP_013609534.1 | conjugal transfer mating pair stabilization protein TraG | - |
| CU111_RS28325 () | 32018..33397 | - | 1380 | WP_014343487.1 | conjugal transfer protein TraH | - |
| CU111_RS28330 () | 33375..33818 | - | 444 | WP_014343488.1 | F-type conjugal transfer protein TrbF | - |
| CU111_RS28335 () | 33864..34421 | - | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| CU111_RS28340 () | 34393..34632 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| CU111_RS28345 () | 34643..35395 | - | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| CU111_RS28350 () | 35416..35742 | - | 327 | WP_004152676.1 | hypothetical protein | - |
| CU111_RS28355 () | 35755..36003 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| CU111_RS28360 () | 35981..36235 | - | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| CU111_RS28365 () | 36267..38222 | - | 1956 | WP_013023827.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| CU111_RS28370 () | 38281..38919 | - | 639 | WP_011977786.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| CU111_RS28375 () | 38932..39921 | - | 990 | WP_009309872.1 | conjugal transfer pilus assembly protein TraU | - |
| CU111_RS28380 () | 39918..40307 | - | 390 | WP_004194992.1 | hypothetical protein | - |
| CU111_RS28385 () | 40349..40975 | - | 627 | WP_009309871.1 | type-F conjugative transfer system protein TraW | - |
| CU111_RS28390 () | 40975..41364 | - | 390 | WP_004197815.1 | type-F conjugative transfer system protein TrbI | - |
| CU111_RS28395 () | 41364..44003 | - | 2640 | WP_013023824.1 | type IV secretion system protein TraC | - |
| CU111_RS28400 () | 44075..44473 | - | 399 | WP_013609531.1 | hypothetical protein | - |
| CU111_RS28410 () | 44849..45253 | - | 405 | WP_004197817.1 | hypothetical protein | - |
| CU111_RS28415 () | 45320..45631 | - | 312 | WP_015344986.1 | hypothetical protein | - |
| CU111_RS28420 () | 45632..45850 | - | 219 | WP_015344987.1 | hypothetical protein | - |
| CU111_RS28425 () | 45956..46366 | - | 411 | WP_009309869.1 | hypothetical protein | - |
| CU111_RS28430 () | 46498..47082 | - | 585 | WP_013023822.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CU111_RS28435 () | 47196..48620 | - | 1425 | WP_004194260.1 | conjugal transfer protein TraB | - |
| CU111_RS28440 () | 48620..49360 | - | 741 | WP_013023821.1 | type-F conjugative transfer system secretin TraK | - |
| CU111_RS28445 () | 49347..49913 | - | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| CU111_RS28450 () | 49933..50238 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| CU111_RS28455 () | 50252..50620 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| CU111_RS28460 () | 50689..50889 | - | 201 | WP_004194116.1 | TraY domain-containing protein | - |
| CU111_RS28465 () | 50975..51676 | - | 702 | WP_004194113.1 | hypothetical protein | - |
| CU111_RS28470 () | 51906..52298 | - | 393 | WP_004194114.1 | relaxosome protein TraM | - |
| CU111_RS28475 () | 52730..53215 | + | 486 | WP_001568108.1 | hypothetical protein | VF |
| CU111_RS28480 () | 53248..53577 | - | 330 | WP_011977736.1 | hypothetical protein | - |
| CU111_RS28485 () | 53610..54431 | - | 822 | WP_004152492.1 | DUF945 domain-containing protein | - |
| CU111_RS28495 () | 55239..56447 | + | 1209 | WP_047665806.1 | IS256 family transposase ISEic2 | Transposase |
| CU111_RS28500 () | 56583..56996 | - | 414 | WP_013023817.1 | helix-turn-helix domain-containing protein | - |
| CU111_RS28505 () | 56997..57275 | - | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| CU111_RS28510 () | 57265..57585 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CU111_RS28515 () | 57666..57890 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| CU111_RS28520 () | 57901..58113 | - | 213 | WP_013023815.1 | hypothetical protein | - |
| CU111_RS28525 () | 58174..58530 | - | 357 | WP_013023814.1 | hypothetical protein | - |
| CU111_RS28540 () | 59372..59689 | - | 318 | WP_013023810.1 | hypothetical protein | - |
| CU111_RS28545 () | 59704..60054 | - | 351 | WP_013023809.1 | hypothetical protein | - |
| CU111_RS28550 () | 60051..60323 | - | 273 | WP_014343506.1 | hypothetical protein | - |
| CU111_RS28555 () | 61016..61174 | - | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| CU111_RS28565 () | 61402..61776 | - | 375 | WP_049181295.1 | hypothetical protein | - |
| CU111_RS28570 () | 61832..62158 | - | 327 | WP_004152639.1 | hypothetical protein | - |
| CU111_RS28575 () | 62155..62883 | - | 729 | WP_064190927.1 | plasmid SOS inhibition protein A | - |
| CU111_RS28580 () | 62880..63311 | - | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| CU111_RS28585 () | 63356..65413 | - | 2058 | WP_049181287.1 | ParB/RepB/Spo0J family partition protein | - |
| CU111_RS28590 () | 65483..65731 | - | 249 | WP_004118972.1 | DUF905 domain-containing protein | - |
| CU111_RS28595 () | 65780..66322 | - | 543 | WP_107326709.1 | single-stranded DNA-binding protein | - |
| CU111_RS28610 () | 67152..67715 | - | 564 | WP_004152756.1 | methyltransferase | - |
| CU111_RS28615 () | 67763..69118 | - | 1356 | WP_015344996.1 | DUF3560 domain-containing protein | - |
| CU111_RS28620 () | 69170..69400 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| CU111_RS28625 () | 69492..69719 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| CU111_RS28645 () | 70399..70719 | - | 321 | WP_001568049.1 | hypothetical protein | - |
| CU111_RS28650 () | 70754..71008 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| CU111_RS28655 () | 71196..71387 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| CU111_RS28660 () | 71430..71936 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| CU111_RS31140 () | 71979..72407 | - | 429 | WP_004152356.1 | antirestriction protein | - |
| CU111_RS28670 () | 73088..73855 | - | 768 | WP_013214013.1 | hypothetical protein | - |
| CU111_RS28675 () | 73909..74328 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| CU111_RS28680 () | 74338..74559 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| CU111_RS28685 () | 74559..75260 | - | 702 | WP_001568041.1 | DNA methylase | - |
| CU111_RS28690 () | 75547..77085 | - | 1539 | WP_022644883.1 | IS66 family transposase ISKpn24 | Transposase |
| CU111_RS28695 () | 77134..77481 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| CU111_RS28700 () | 77478..77882 | - | 405 | WP_007372134.1 | IS66 family transposase ISKpn24 | Transposase |
| CU111_RS28705 () | 78159..78389 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| CU111_RS28710 () | 78453..79124 | - | 672 | WP_015345000.1 | plasmid partitioning/stability family protein | - |
| CU111_RS28715 () | 79127..80098 | - | 972 | WP_001568038.1 | hypothetical protein | - |
| CU111_RS28720 () | 80347..81834 | - | 1488 | WP_199855255.1 | Group II intron-encoded protein LtrA | VF |
| CU111_RS28730 () | 82241..82672 | + | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CU111_RS28735 () | 82672..83943 | + | 1272 | WP_004197646.1 | Y-family DNA polymerase | - |
| CU111_RS28740 () | 84355..85230 | + | 876 | WP_004098982.1 | RepB family plasmid replication initiator protein | - |
| CU111_RS28745 () | 85903..86529 | + | 627 | WP_004197649.1 | Chromosome-partitioning ATPase Soj | VF |
| CU111_RS28750 () | 86649..86828 | + | 180 | WP_006788217.1 | hypothetical protein | - |
| CU111_RS28755 () | 87260..88054 | - | 795 | WP_004197635.1 | site-specific integrase | - |
| CU111_RS28760 () | 88252..89268 | - | 1017 | WP_017899884.1 | hypothetical protein | - |
| CU111_RS28765 () | 89279..89593 | - | 315 | WP_053389906.1 | hypothetical protein | - |
| CU111_RS28770 () | 89620..90015 | - | 396 | WP_017899885.1 | hypothetical protein | - |
| CU111_RS28775 () | 90184..90489 | - | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| CU111_RS28780 () | 90491..90709 | - | 219 | WP_001568025.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| CU111_RS28800 () | 91527..91817 | - | 291 | WP_013023783.1 | hypothetical protein | - |
| CU111_RS28805 () | 91814..92941 | - | 1128 | WP_013023782.1 | DUF4238 domain-containing protein | - |
| CU111_RS28810 () | 92975..94567 | - | 1593 | WP_015344964.1 | hypothetical protein | - |
| CU111_RS28815 () | 94774..95553 | - | 780 | WP_013023780.1 | hypothetical protein | - |
| CU111_RS28820 () | 95566..96066 | - | 501 | WP_013023779.1 | hypothetical protein | - |
| CU111_RS28825 () | 96341..96604 | + | 264 | WP_013023778.1 | hypothetical protein | - |
| CU111_RS28830 () | 96601..97167 | + | 567 | WP_013023777.1 | hypothetical protein | - |
| CU111_RS28835 () | 97198..97692 | + | 495 | WP_013023776.1 | hypothetical protein | - |
| CU111_RS28840 () | 97736..98104 | + | 369 | WP_015344965.1 | hypothetical protein | - |
| CU111_RS28845 () | 98138..98341 | + | 204 | WP_004098931.1 | hemolysin expression modulator Hha | - |
| CU111_RS28850 () | 98390..98647 | + | 258 | WP_017899889.1 | hypothetical protein | - |
| CU111_RS28855 () | 98723..98977 | + | 255 | WP_009653916.1 | hypothetical protein | - |
| CU111_RS28860 () | 99113..99889 | - | 777 | WP_013609504.1 | DUF2971 domain-containing protein | - |
| CU111_RS28865 () | 100130..100453 | - | 324 | WP_017899891.1 | hypothetical protein | - |
| CU111_RS28870 () | 100632..100901 | - | 270 | Protein_123 | SOS response-associated peptidase family protein | - |
| CU111_RS28880 () | 101037..101204 | + | 168 | Protein_124 | IS5 family transposase IS903 | Transposase |
| CU111_RS28885 () | 101260..101409 | + | 150 | Protein_125 | IS110 family transposase | - |
| CU111_RS28890 () | 101692..102678 | + | 987 | Protein_126 | DUF4268 domain-containing protein | - |
| CU111_RS28895 () | 102712..105609 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| CU111_RS28900 () | 105704..106309 | + | 606 | WP_031942267.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| CU111_RS28905 () | 106342..106542 | + | 201 | Protein_129 | DUF4268 domain-containing protein | - |
| CU111_RS28920 () | 107734..108591 | - | 858 | WP_013023768.1 | incFII family plasmid replication initiator RepA | - |
| CU111_RS28925 () | 108584..108661 | - | 78 | WP_004171457.1 | RepA leader peptide Tap | - |
| CU111_RS28930 () | 108893..109162 | - | 270 | WP_013609506.1 | replication regulatory protein RepA | - |
| CU111_RS28935 () | 109280..109759 | - | 480 | WP_014343478.1 | Phospholipase D | VF |
| CU111_RS28940 () | 109963..110979 | - | 1017 | Protein_134 | methyl-accepting chemotaxis protein | - |
| CU111_RS28945 () | 111043..111747 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CU111_RS28955 () | 111797..112516 | + | 720 | Protein_136 | AAA family ATPase | - |
| CU111_RS28960 () | 112503..113354 | + | 852 | WP_000240536.1 | replication protein | - |
| CU111_RS28970 () | 113662..114477 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| CU111_RS28975 () | 114538..115341 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| CU111_RS28980 () | 115341..116177 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| CU111_RS28985 () | 116238..116942 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CU111_RS28990 () | 117093..117908 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| CU111_RS28995 () | 118098..118802 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CU111_RS29000 () | 119035..119895 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| CU111_RS29005 () | 119908..120201 | + | 294 | Protein_145 | tunicamycin resistance protein | - |
| CU111_RS29010 () | 120264..120968 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CU111_RS29020 () | 121090..121995 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| CU111_RS29025 () | 121992..123230 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| CU111_RS29030 () | 123230..123814 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| CU111_RS29045 () | 124307..125071 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| CU111_RS31145 () | 125189..125254 | - | 66 | Protein_151 | EAL domain-containing protein | - |
| CU111_RS29055 () | 125298..125603 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| CU111_RS29060 () | 125614..126819 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| CU111_RS29065 () | 127047..128051 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| CU111_RS29070 () | 128233..128436 | - | 204 | WP_064765192.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|