MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 111310 bp
Accession: NZ_CP024805 Location: 1..111310 Organism: Escherichia coli strain AMA1167 Replicon: plasmid pAMA1167-NDM-5
Accession: NZ_CP024805 Location: 1..111310 Organism: Escherichia coli strain AMA1167 Replicon: plasmid pAMA1167-NDM-5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CUC42_RS24530 () | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| CUC42_RS24535 () | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| CUC42_RS24540 () | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| CUC42_RS24550 () | 2649..2956 | - | 308 | Protein_3 | type II toxin-antitoxin system ParD family antitoxin | - |
| CUC42_RS24560 () | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| CUC42_RS24565 () | 4651..4779 | + | 129 | Protein_5 | IS481 family transposase | - |
| CUC42_RS24570 () | 4814..5008 | - | 195 | WP_086258557.1 | hypothetical protein | - |
| CUC42_RS24580 () | 5050..5747 | + | 698 | Protein_7 | IS1 family transposase IS1R | Transposase |
| CUC42_RS24585 () | 5763..5882 | + | 120 | Protein_8 | ArsR family transcriptional regulator | - |
| CUC42_RS24590 () | 5860..6483 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| CUC42_RS24595 () | 6565..7770 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| CUC42_RS24600 () | 7883..8476 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| CUC42_RS24605 () | 8610..9314 | + | 705 | WP_100608384.1 | IS6-like element IS26 family transposase | - |
| CUC42_RS24610 () | 9368..9733 | - | 366 | Protein_13 | chromate transporter | - |
| CUC42_RS24615 () | 9889..10092 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| CUC42_RS24625 () | 10220..11059 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| CUC42_RS24630 () | 11053..11400 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| CUC42_RS24635 () | 11606..12394 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| CUC42_RS24640 () | 12525..12998 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| CUC42_RS24645 () | 13156..14169 | + | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| CUC42_RS26015 () | 14372..14518 | + | 147 | Protein_20 | EAL domain-containing protein | - |
| CUC42_RS24660 () | 14571..15275 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| CUC42_RS24665 () | 15440..15733 | + | 294 | Protein_22 | IS30 family transposase ISAba125 | Transposase |
| CUC42_RS24670 () | 15834..16646 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| CUC42_RS24675 () | 16650..17015 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| CUC42_RS24680 () | 17020..17658 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| CUC42_RS24685 () | 17669..18700 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| CUC42_RS24695 () | 19013..20554 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| CUC42_RS24700 () | 20959..21798 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| CUC42_RS24705 () | 21792..22139 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| CUC42_RS24710 () | 22303..23094 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| CUC42_RS25850 () | 23100..23390 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| CUC42_RS24715 () | 23502..23999 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| CUC42_RS24720 () | 24144..25010 | + | 867 | Protein_33 | class 1 integron integrase IntI1 | - |
| CUC42_RS24725 () | 25065..25769 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| CUC42_RS24730 () | 25928..26209 | - | 282 | Protein_35 | transposase zinc-binding domain-containing protein | - |
| CUC42_RS24735 () | 26356..27216 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| CUC42_RS24740 () | 27399..27590 | - | 192 | Protein_37 | Tn3 family transposase TnpR_Tn3 | Transposase |
| CUC42_RS24745 () | 27654..28358 | + | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| CUC42_RS24750 () | 28413..29258 | - | 846 | Protein_39 | IS4 family transposase IS10R | Transposase |
| CUC42_RS24755 () | 29368..30330 | - | 963 | Protein_40 | IS4 family transposase IS10R | Transposase |
| CUC42_RS24760 () | 30473..31333 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| CUC42_RS24765 () | 31346..31888 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| CUC42_RS24770 () | 32370..32561 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| CUC42_RS24775 () | 32585..32812 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| CUC42_RS24780 () | 32863..33990 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| CUC42_RS24785 () | 34027..34731 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| CUC42_RS24795 () | 34853..35758 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| CUC42_RS24800 () | 35755..36993 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| CUC42_RS24805 () | 36993..37577 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| CUC42_RS24820 () | 38070..38834 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| CUC42_RS24825 () | 38974..39678 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| CUC42_RS24830 () | 39739..40575 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| CUC42_RS24835 () | 40575..41378 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| CUC42_RS24840 () | 41439..42254 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| CUC42_RS24850 () | 42562..43413 | - | 852 | WP_000240536.1 | replication protein | - |
| CUC42_RS24855 () | 43400..44119 | - | 720 | Protein_56 | AAA family ATPase | - |
| CUC42_RS24865 () | 44169..44873 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| CUC42_RS24870 () | 44937..45608 | + | 672 | Protein_58 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| CUC42_RS24875 () | 45833..46474 | - | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| CUC42_RS24880 () | 46714..47034 | - | 321 | Protein_60 | IS1380 family transposase ISEcp1 | Transposase |
| CUC42_RS24885 () | 47047..47607 | + | 561 | WP_000147567.1 | recombinase family protein | - |
| CUC42_RS24890 () | 47610..50081 | + | 2472 | Protein_62 | Tn3-like element TnAs3 family transposase | - |
| CUC42_RS24895 () | 50228..51088 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| CUC42_RS24900 () | 51271..51609 | - | 339 | Protein_64 | Tn3 family transposase TnpR_Tn3 | Transposase |
| CUC42_RS24905 () | 51673..52377 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| CUC42_RS24915 () | 52759..53634 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| CUC42_RS24920 () | 53681..54013 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| CUC42_RS24925 () | 54027..56270 | + | 2244 | Protein_68 | Tn3 family transposase TnpA_Tn3 | Transposase |
| CUC42_RS24930 () | 56335..57039 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| CUC42_RS24935 () | 57093..57533 | - | 441 | Protein_70 | CatB-related O-acetyltransferase | - |
| CUC42_RS24940 () | 57671..58501 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| CUC42_RS24945 () | 58632..59186 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| CUC42_RS24950 () | 59330..60034 | - | 705 | WP_100608385.1 | IS6-like element IS26 family transposase | - |
| CUC42_RS24955 () | 60097..62442 | + | 2346 | Protein_74 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| CUC42_RS24965 () | 62579..62980 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| CUC42_RS25855 () | 62913..63170 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| CUC42_RS24970 () | 63263..63916 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| CUC42_RS24980 () | 64856..65713 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| CUC42_RS24985 () | 65706..65780 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| CUC42_RS26020 () | 65777..65911 | - | 135 | Protein_80 | protein CopA/IncA | - |
| CUC42_RS24995 () | 66142..67683 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| CUC42_RS25000 () | 67698..68444 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| CUC42_RS25005 () | 68604..68858 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| CUC42_RS25010 () | 69155..69289 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 69334..69394 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69334..69394 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69334..69394 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69334..69394 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| CUC42_RS26025 () | 69361..69647 | - | 287 | Protein_85 | DUF2726 domain-containing protein | - |
| CUC42_RS25025 () | 70160..70372 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| CUC42_RS25030 () | 70503..71063 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| CUC42_RS25035 () | 71118..71864 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| CUC42_RS25040 () | 71884..74277 | - | 2394 | Protein_89 | Multifunctional conjugation protein TraI | Relaxase |
| CUC42_RS25045 () | 74247..75329 | - | 1083 | WP_060621339.1 | DUF3560 domain-containing protein | - |
| CUC42_RS25050 () | 75381..75611 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| CUC42_RS25060 () | 77008..78675 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| CUC42_RS25065 () | 78989..79180 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| CUC42_RS25070 () | 79177..79599 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| CUC42_RS25075 () | 79646..79948 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| CUC42_RS25860 () | 80488..81264 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| CUC42_RS25090 () | 81315..81749 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| CUC42_RS25095 () | 81763..81984 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| CUC42_RS25100 () | 81985..82668 | - | 684 | WP_000086185.1 | DNA methylase | - |
| CUC42_RS25105 () | 82745..83049 | - | 305 | Protein_100 | hypothetical protein | - |
| CUC42_RS25110 () | 83053..83955 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| CUC42_RS25125 () | 84822..85793 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| CUC42_RS25130 () | 85793..86959 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| CUC42_RS25135 () | 87547..88302 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| CUC42_RS25140 () | 89076..89882 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| CUC42_RS25145 () | 89883..90188 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| CUC42_RS25150 () | 90190..90408 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| CUC42_RS25155 () | 91042..91239 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| CUC42_RS25160 () | 91236..91520 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| CUC42_RS25165 () | 91540..92673 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| CUC42_RS25170 () | 92936..96055 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| CUC42_RS25180 () | 96362..96592 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| CUC42_RS25185 () | 96589..97005 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| CUC42_RS25190 () | 97167..99305 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| CUC42_RS25195 () | 99770..100765 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| CUC42_RS25200 () | 100769..101701 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| CUC42_RS25205 () | 101838..102535 | - | 698 | Protein_117 | IS1 family transposase IS1R | Transposase |
| CUC42_RS25215 () | 102749..105865 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| CUC42_RS25220 () | 105987..107270 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| CUC42_RS25225 () | 107267..108823 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| CUC42_RS25230 () | 109006..109227 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| CUC42_RS25235 () | 109227..109607 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| CUC42_RS25240 () | 109612..109791 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| CUC42_RS25245 () | 109819..110178 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| CUC42_RS25250 () | 110102..110515 | + | 414 | Protein_125 | IS3 family transposase ISLad1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|