NZ_CP0241331..190293

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 190293 bp
Accession: NZ_CP024133        Location: 1..190293         Organism: Escherichia coli strain 14EC007       Replicon: plasmid p14EC007b


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR535_RS27420 () 60..1273 + 1214 WP_162829241.1 IS3 family transposase IS629 Transposase
CR535_RS29030 () 1311..1796 + 486 Protein_1 IS3 family transposase IS3 Transposase
CR535_RS27430 () 2255..4915 + 2661 WP_000770132.1 Metalloprotease StcE VF
CR535_RS27435 () 4999..5874 + 876 WP_001368871.1 Type II secretion system protein C VF
CR535_RS27440 () 5875..7845 + 1971 WP_013009342.1 Type II secretion system protein D VF
CR535_RS27445 () 7842..9344 + 1503 WP_001418198.1 Type II secretion system protein E VF
CR535_RS27450 () 9346..10569 + 1224 WP_001173149.1 Type II secretion system protein F VF
CR535_RS27455 () 10600..11034 + 435 WP_001231213.1 Type II secretion system protein G VF
CR535_RS27460 () 11031..11582 + 552 WP_000082928.1 type II secretion system minor pseudopilin GspH -
CR535_RS27465 () 11597..11944 + 348 WP_001420206.1 Type II secretion system protein I VF
CR535_RS27470 () 11941..12540 + 600 WP_000082784.1 Type II secretion system protein J VF
CR535_RS27475 () 12537..13514 + 978 WP_000842183.1 Putative type II secretion system protein K VF
CR535_RS27480 () 13553..14725 + 1173 WP_071526091.1 Type II secretion system protein L VF
CR535_RS27485 () 14712..15227 + 516 WP_000998852.1 Type II secretion system protein M VF
CR535_RS27490 () 15279..16112 + 834 WP_000088802.1 Type 4 prepilin-like proteins leader peptide-processing enzyme VF
CR535_RS27495 () 16206..16607 + 402 WP_001222320.1 GspS family T2SS pilot lipoprotein variant EptO -
CR535_RS27500 () 16682..16897 + 216 Protein_16 IS3 family transposase IS1203 Transposase
CR535_RS29035 () 17196..17489 + 294 Protein_17 hypothetical protein -
CR535_RS27515 () 17718..17966 + 249 WP_000083841.1 replication regulatory protein RepA -
CR535_RS29040 () 17989..18096 + 108 Protein_19 incFII family plasmid replication initiator RepA -
CR535_RS27525 () 19050..19301 + 252 WP_001132900.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
CR535_RS27530 () 19298..19585 + 288 WP_000222766.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
CR535_RS27540 () 21702..25604 + 3903 WP_001045657.1 Serine protease EspP VF
CR535_RS27555 () 27458..27616 + 159 WP_001312823.1 integrase core domain-containing protein -
CR535_RS27565 () 28396..28785 - 390 WP_001332050.1 IS110 family transposase ISEc20 Transposase
CR535_RS27570 () 28889..29842 + 954 WP_000280980.1 Protease 7 VF
CR535_RS27580 () 31301..32013 + 713 Protein_29 hypothetical protein VF
CR535_RS27585 () 32387..32575 + 189 WP_014640565.1 hypothetical protein -
CR535_RS27590 () 32696..33436 + 741 WP_001066954.1 tyrosine-type recombinase/integrase -
CR535_RS27595 () 33721..34698 - 978 WP_000361611.1 RepB family plasmid replication initiator protein -
CR535_RS27605 () 35444..35767 + 324 Protein_33 IS21 family transposase IS21 Transposase
CR535_RS29045 () 35769..35873 + 105 Protein_34 AAA family ATPase -
CR535_RS27615 () 35934..36447 + 514 Protein_35 DUF4113 domain-containing protein -
CR535_RS27620 () 36627..37324 - 698 Protein_36 IS1 family transposase IS1G Transposase
CR535_RS27635 () 37481..38501 + 1021 Protein_37 IS21 family transposase IS100kyp Transposase
CR535_RS27640 () 38498..39283 + 786 WP_101973083.1 IS21 family transposase IS100kyp Transposase
CR535_RS27645 () 39309..40522 + 1214 WP_162829241.1 IS3 family transposase IS629 Transposase
CR535_RS27660 () 40950..41864 + 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
CR535_RS27665 () 41864..42691 + 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
CR535_RS27670 () 42688..43545 + 858 WP_000992806.1 Manganese transport system membrane protein MntB ARG
CR535_RS27675 () 43542..44399 + 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
CR535_RS27680 () 44633..44890 - 258 Protein_44 Tn3 family transposase -
CR535_RS27685 () 44888..45019 + 132 Protein_45 phosphopyruvate hydratase -
CR535_RS27690 () 45016..45243 - 228 Protein_46 malate dehydrogenase -
CR535_RS27710 () 45951..46648 + 698 Protein_47 IS1 family transposase IS1G Transposase
CR535_RS27715 () 46948..48114 + 1167 WP_001238646.1 Sporulation initiation inhibitor protein Soj VF
CR535_RS27720 () 48114..49085 + 972 WP_000817028.1 ParB/RepB/Spo0J family plasmid partition protein -
CR535_RS27730 () 50084..51195 - 1112 Protein_50 IS4 family transposase IS421 Transposase
CR535_RS27740 () 51652..51984 + 333 Protein_51 hypothetical protein -
CR535_RS27750 () 52038..52735 + 698 Protein_52 IS1 family transposase IS1S Transposase
CR535_RS27755 () 52747..53004 + 258 Protein_53 hypothetical protein -
CR535_RS27760 () 53017..53229 + 213 WP_000092896.1 hypothetical protein -
CR535_RS27765 () 53490..54461 - 972 WP_000082154.1 IS110 family transposase ISEc32 Transposase
CR535_RS27775 () 54986..55288 + 303 WP_072256028.1 antirestriction protein -
CR535_RS27780 () 55288..55749 + 462 WP_042007484.1 DUF1380 family protein -
CR535_RS27785 () 55749..55931 + 183 WP_001027505.1 hypothetical protein -
CR535_RS29050 () 55919..56247 - 329 Protein_59 pilus assembly protein -
CR535_RS27805 () 56925..57155 + 231 WP_000218642.1 hypothetical protein -
CR535_RS27810 () 57207..58568 + 1362 WP_000170681.1 DUF3560 domain-containing protein -
CR535_RS27815 () 58614..59177 + 564 WP_001311069.1 class I SAM-dependent methyltransferase -
CR535_RS27830 () 60116..60643 + 528 WP_000290793.1 single-stranded DNA-binding protein -
CR535_RS27835 () 60699..60932 + 234 WP_000006004.1 DUF905 domain-containing protein -
CR535_RS27840 () 60991..62949 + 1959 WP_001145469.1 ParB/RepB/Spo0J family partition protein -
CR535_RS27845 () 63004..63438 + 435 WP_000845895.1 conjugation system SOS inhibitor PsiB -
CR535_RS27850 () 63435..64154 + 720 WP_001276228.1 plasmid SOS inhibition protein A -
CR535_RS27855 () 64166..64354 - 189 WP_001299721.1 hypothetical protein -
- () 64166..64390 + 225 NuclAT_0 - -
- () 64166..64390 + 225 NuclAT_0 - -
- () 64166..64390 + 225 NuclAT_0 - -
- () 64166..64390 + 225 NuclAT_0 - -
- () 64323..64388 + 66 - - Antitoxin Detail
CR535_RS27860 () 64434..64592 + 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
CR535_RS27880 () 65514..65801 + 288 WP_000107535.1 hypothetical protein -
CR535_RS27885 () 65921..66742 + 822 WP_001241365.1 DUF945 domain-containing protein -
CR535_RS27890 () 67039..67641 - 603 WP_000243705.1 hypothetical protein VF
CR535_RS27895 () 67962..68345 + 384 WP_001151524.1 relaxosome protein TraM -
CR535_RS27900 () 68532..69221 + 690 WP_000283379.1 conjugal transfer transcriptional regulator TraJ -
CR535_RS27905 () 69320..69715 + 396 WP_001309237.1 conjugal transfer relaxosome protein TraY -
CR535_RS27910 () 69748..70113 + 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
CR535_RS27915 () 70128..70439 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
CR535_RS27920 () 70461..71027 + 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
CR535_RS27925 () 71038..71742 + 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
CR535_RS27930 () 71742..73169 + 1428 WP_101973086.1 conjugal transfer protein TraB -
CR535_RS27935 () 73159..73749 + 591 WP_000002784.1 conjugal transfer protein TraP -
CR535_RS27940 () 73688..74053 + 366 WP_051049367.1 conjugal transfer protein TrbD -
CR535_RS27945 () 74053..74568 + 516 WP_000724020.1 type IV conjugative transfer system lipoprotein TraV -
CR535_RS27950 () 74703..74924 + 222 WP_000064029.1 conjugal transfer protein TraR -
CR535_RS27955 () 75084..77711 + 2628 WP_050195440.1 type IV secretion system protein TraC -
CR535_RS27960 () 77708..78094 + 387 WP_000214096.1 type-F conjugative transfer system protein TrbI -
CR535_RS27965 () 78091..78723 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
CR535_RS27970 () 78720..79712 + 993 WP_000830839.1 conjugal transfer pilus assembly protein TraU -
CR535_RS27975 () 79721..80359 + 639 WP_000777692.1 type-F conjugative transfer system pilin assembly protein TrbC -
CR535_RS27980 () 80356..82206 + 1851 WP_032283054.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CR535_RS27985 () 82233..82490 + 258 WP_000864341.1 conjugal transfer protein TrbE -
CR535_RS27990 () 82483..83226 + 744 WP_046788511.1 type-F conjugative transfer system pilin assembly protein TraF -
CR535_RS27995 () 83342..83623 + 282 WP_000549795.1 type-F conjugative transfer system pilin chaperone TraQ -
CR535_RS28000 () 83610..84155 + 546 WP_044804936.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CR535_RS28005 () 84085..84447 + 363 WP_072078458.1 P-type conjugative transfer protein TrbJ -
CR535_RS28010 () 84447..85820 + 1374 WP_050195262.1 conjugal transfer protein TraH -
CR535_RS28015 () 85817..88639 + 2823 WP_046788512.1 conjugal transfer mating pair stabilization protein TraG -
CR535_RS28020 () 88654..89157 + 504 WP_000605510.1 hypothetical protein -
CR535_RS28025 () 89189..89920 + 732 WP_000850424.1 complement resistance protein TraT -
CR535_RS28030 () 90172..92388 + 2217 WP_022630316.1 type IV conjugative transfer system coupling protein TraD -
CR535_RS28035 () 92388..97658 + 5271 WP_101973087.1 Multifunctional conjugation protein TraI Relaxase
CR535_RS28040 () 97678..98423 + 746 Protein_102 conjugal transfer pilus acetylase TraX -
CR535_RS28045 () 98478..99038 + 561 WP_000139345.1 fertility inhibition protein FinO -
CR535_RS28055 () 99130..99827 + 698 Protein_104 IS1 family transposase IS1S Transposase
CR535_RS28060 () 99820..99963 + 144 WP_072078460.1 hypothetical protein -
CR535_RS28065 () 100002..100592 + 591 WP_000766814.1 DUF2726 domain-containing protein -
CR535_RS28070 () 100832..101086 + 255 WP_000083830.1 replication regulatory protein RepA -
CR535_RS28080 () 101324..101398 + 75 WP_001365705.1 RepA leader peptide Tap -
CR535_RS28085 () 101391..102248 + 858 WP_158297019.1 incFII family plasmid replication initiator RepA -
CR535_RS28095 () 103186..103839 + 654 WP_000616800.1 CPBP family intramembrane metalloprotease -
CR535_RS28905 () 103932..104189 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
CR535_RS28100 () 104122..104523 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
CR535_RS28110 () 104808..106580 + 1773 WP_001262766.1 DUF262 domain-containing protein -
CR535_RS28120 () 107517..108521 - 1005 WP_000427620.1 IS110 family transposase IS4321 Transposase
CR535_RS28125 () 108600..109034 - 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
CR535_RS28130 () 109106..109456 + 351 WP_001294663.1 mercuric transport protein MerT -
CR535_RS28135 () 109470..109745 + 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
CR535_RS28140 () 109781..110203 + 423 WP_001340589.1 organomercurial transporter MerC -
CR535_RS28145 () 110255..111949 + 1695 WP_000105636.1 mercury(II) reductase -
CR535_RS28150 () 111967..112329 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
CR535_RS28155 () 112326..112562 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
CR535_RS28160 () 112598..113266 + 669 WP_001300294.1 putative signaling protein VF
CR535_RS28170 () 113341..114591 + 1251 Protein_123 DDE-type integrase/transposase/recombinase -
CR535_RS28175 () 114656..115360 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
CR535_RS28180 () 115433..115672 + 240 WP_011264039.1 macrolide transporter -
CR535_RS28185 () 115818..116681 + 864 WP_000612791.1 SDR family oxidoreductase -
CR535_RS28190 () 116719..116964 + 246 WP_001354008.1 GrpB family protein -
CR535_RS28195 () 117433..118224 + 792 WP_000034420.1 Dihydropteroate synthase ARG
CR535_RS29055 () 118227..118502 - 276 WP_109023896.1 hypothetical protein -
CR535_RS28200 () 118504..119139 + 636 Protein_130 IS256 family transposase IS406 Transposase
CR535_RS28210 () 119560..120531 + 972 WP_032482493.1 IS91 family transposase ISAzo26 Transposase
CR535_RS28215 () 120828..121457 + 630 Protein_132 IS5 family transposase -
CR535_RS28220 () 121521..122225 + 705 WP_001067858.1 IS6-like element IS26 family transposase -
CR535_RS28230 () 122280..122510 + 231 Protein_134 peptidase -
CR535_RS28235 () 122510..123781 + 1272 WP_000457559.1 Y-family DNA polymerase -
CR535_RS28240 () 123863..124837 - 975 WP_000064119.1 ParB/RepB/Spo0J family partition protein -
CR535_RS28245 () 124837..126042 - 1206 WP_000368714.1 AAA family ATPase -
CR535_RS28250 () 126457..126726 + 270 WP_000339857.1 hypothetical protein -
CR535_RS28255 () 126903..127769 - 867 WP_004118283.1 replication initiation protein -
CR535_RS29060 () 128299..128403 + 105 WP_032409716.1 hypothetical protein -
CR535_RS28260 () 128532..128789 + 258 WP_000764642.1 hypothetical protein -
CR535_RS28265 () 128847..129623 - 777 WP_000015958.1 site-specific integrase -
CR535_RS28270 () 129620..130363 - 744 WP_000129823.1 hypothetical protein -
CR535_RS28275 () 130414..130764 - 351 WP_000493378.1 hypothetical protein -
CR535_RS28285 () 131332..132306 - 975 WP_011251353.1 sensor domain-containing diguanylate cyclase -
CR535_RS28290 () 132944..133852 + 909 WP_001372261.1 HNH endonuclease -
CR535_RS28295 () 134240..134590 - 351 WP_000694953.1 DUF305 domain-containing protein -
CR535_RS28300 () 134734..135165 - 432 WP_000790483.1 silver-binding protein SilE -
CR535_RS28305 () 135416..136891 - 1476 WP_000555737.1 copper/silver sensor histidine kinase SilS -
CR535_RS28310 () 136884..137564 - 681 WP_000697965.1 Transcriptional regulatory protein CusR VF
CR535_RS28320 () 137754..139139 + 1386 WP_038988996.1 Cation efflux system protein CusC VF
CR535_RS28325 () 139167..139520 + 354 WP_001246155.1 cation efflux system protein CusF -
CR535_RS28330 () 139634..140926 + 1293 WP_001398209.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
CR535_RS28335 () 140937..144083 + 3147 WP_011251357.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
CR535_RS28340 () 144170..144610 + 441 WP_000758221.1 hypothetical protein -
CR535_RS28345 () 144708..147185 + 2478 WP_001398208.1 Ag(+)-translocating P-type ATPase SilP -
CR535_RS28350 () 147226..147423 + 198 WP_000843496.1 DUF2933 domain-containing protein -
CR535_RS28355 () 147457..148194 - 738 WP_000287499.1 Murein DD-endopeptidase MepM VF
CR535_RS28360 () 148419..149279 - 861 WP_000027057.1 Beta-lactamase TEM ARG
CR535_RS28365 () 149462..149923 - 462 Protein_160 Tn3 family transposase TnpR_Tn3 Transposase
CR535_RS28370 () 149986..150690 + 705 WP_001067858.1 IS6-like element IS26 family transposase -
CR535_RS28380 () 150962..151618 - 657 WP_001516695.1 Pentapeptide repeat protein ARG
CR535_RS28385 () 152013..152629 + 617 Protein_163 transposase -
CR535_RS28390 () 152696..153400 + 705 WP_086525284.1 IS6-like element IS26 family transposase -
CR535_RS28395 () 153454..154458 - 1005 Protein_165 IS91 family transposase ISAzo26 Transposase
CR535_RS28400 () 154603..155100 + 498 WP_001083725.1 Dihydrofolate reductase ARG
CR535_RS28910 () 155212..155502 + 291 WP_001336345.1 DUF1010 domain-containing protein -
CR535_RS28405 () 155508..156299 + 792 WP_001206356.1 Streptomycin 3''-adenylyltransferase ARG
CR535_RS28410 () 156784..157176 + 393 WP_000084745.1 pyridoxamine 5'-phosphate oxidase family protein -
CR535_RS28415 () 157496..157882 - 387 WP_063102497.1 bleomycin binding protein -
CR535_RS28425 () 158022..158726 - 705 WP_001067858.1 IS6-like element IS26 family transposase -
CR535_RS28435 () 158897..159325 - 429 Protein_172 Tn3 family transposase TnpR_ISMex22 Transposase
CR535_RS28440 () 159358..160749 - 1392 WP_001493761.1 ISKra4 family transposase ISKpn19 Transposase
CR535_RS28445 () 160786..161358 - 573 WP_001493762.1 Tn3 family transposase TnpR_ISPa40 Transposase
CR535_RS28450 () 161495..162085 - 591 WP_012477564.1 plasmid pRiA4b ORF-3 family protein -
CR535_RS28455 () 162203..162445 + 243 WP_000844627.1 transposase -
CR535_RS28460 () 162477..163127 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
CR535_RS28465 () 163233..164432 + 1200 WP_001493765.1 Tetracycline resistance protein, class C ARG
CR535_RS28470 () 164464..165348 - 885 WP_101973090.1 EamA family transporter -
CR535_RS28475 () 165486..165893 - 408 WP_039022039.1 cysteine hydrolase -
CR535_RS28480 () 165882..167633 + 1752 Protein_181 Tn3 family transposase TnpA_TnAs1 Transposase
CR535_RS28485 () 167668..169548 + 1881 Protein_182 type IV conjugative transfer system coupling protein TraD -
CR535_RS28490 () 169548..174818 + 5271 WP_101973091.1 Multifunctional conjugation protein TraI Relaxase
CR535_RS28495 () 174838..175584 + 747 WP_000205715.1 conjugal transfer pilus acetylase TraX -
CR535_RS28500 () 175643..176503 + 861 WP_000704529.1 putative protein YcjY VF
CR535_RS28505 () 176606..177166 + 561 WP_000139321.1 fertility inhibition protein FinO -
CR535_RS28510 () 177316..177696 + 381 WP_001171554.1 IS66 family transposase ISEc8 Transposase
CR535_RS28515 () 177693..178040 + 348 WP_000612591.1 IS66 family transposase ISEc8 Transposase
CR535_RS28520 () 178090..179628 + 1539 WP_053888474.1 IS66 family transposase ISEc8 Transposase
CR535_RS28525 () 179691..179840 - 150 Protein_190 IS3 family transposase -
CR535_RS28530 () 179932..180930 - 999 WP_077629919.1 Lipid A biosynthesis myristoyltransferase VF
CR535_RS28535 () 181004..182725 - 1722 WP_000550559.1 phosphoethanolamine transferase CptA -
CR535_RS28540 () 182819..183925 - 1107 WP_000975743.1 glycosyltransferase family 4 protein -
CR535_RS28545 () 183925..184746 - 822 WP_001302199.1 polysaccharide deacetylase family protein -
CR535_RS28560 () 187531..187920 - 390 WP_001172748.1 cytochrome b562 family protein -
CR535_RS28565 () 187964..190174 - 2211 WP_000592771.1 Catalase-peroxidase VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance