MGE detailed information
MGE type: Conjugative plasmid MGE length: 161452 bp
Accession: NZ_CP023542 Location: 1..161452 Organism: Escherichia coli O104:H21 str. CFSAN002236 strain ATCC BAA-178 Replicon: plasmid pO104_H21
Accession: NZ_CP023542 Location: 1..161452 Organism: Escherichia coli O104:H21 str. CFSAN002236 strain ATCC BAA-178 Replicon: plasmid pO104_H21
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CR208_RS23825 () | 570..1022 | + | 453 | WP_021292781.1 | type IV pilus biogenesis protein PilP | - |
| CR208_RS23830 () | 1107..2615 | + | 1509 | WP_000886636.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| CR208_RS23835 () | 2617..3717 | + | 1101 | WP_021292782.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| CR208_RS23840 () | 3791..4327 | + | 537 | WP_040118365.1 | cleavage protein | - |
| CR208_RS23845 () | 4381..4854 | + | 474 | WP_000870986.1 | hypothetical protein | VF |
| CR208_RS23850 () | 4873..5505 | + | 633 | WP_021292783.1 | prepilin peptidase | - |
| CR208_RS23855 () | 5510..6874 | + | 1365 | WP_021292784.1 | hypothetical protein | VF |
| CR208_RS23870 () | 7332..7622 | + | 291 | WP_021292787.1 | hypothetical protein | - |
| CR208_RS23875 () | 7714..8034 | - | 321 | WP_021292788.1 | hypothetical protein | - |
| CR208_RS23880 () | 8294..9115 | + | 822 | WP_021292789.1 | hypothetical protein | - |
| CR208_RS23885 () | 9205..10407 | + | 1203 | WP_021292790.1 | conjugal transfer protein TraF | - |
| CR208_RS24895 () | 10547..10717 | + | 171 | WP_021292791.1 | hypothetical protein | - |
| CR208_RS23890 () | 10766..11218 | + | 453 | WP_001081199.1 | DotD/TraH family lipoprotein | - |
| CR208_RS23895 () | 11215..12051 | + | 837 | WP_000848138.1 | hypothetical protein | VF |
| CR208_RS23900 () | 12035..13183 | + | 1149 | WP_021292792.1 | putative protein YggR | VF |
| CR208_RS23905 () | 13180..13470 | + | 291 | WP_000817799.1 | hypothetical protein | - |
| CR208_RS23910 () | 13534..17556 | + | 4023 | WP_021292793.1 | DNA primase | - |
| CR208_RS23915 () | 17573..17923 | + | 351 | WP_001056369.1 | hypothetical protein | - |
| CR208_RS23920 () | 17935..18630 | + | 696 | WP_001287263.1 | DotI/IcmL family type IV secretion protein | - |
| CR208_RS23925 () | 18641..19615 | + | 975 | WP_001165564.1 | hypothetical protein | VF |
| CR208_RS23930 () | 19619..20950 | + | 1332 | WP_021292795.1 | conjugal transfer protein TraO | - |
| CR208_RS23935 () | 20947..21660 | + | 714 | WP_021292796.1 | conjugal transfer protein TraP | - |
| CR208_RS23940 () | 21660..22187 | + | 528 | WP_001379391.1 | conjugal transfer protein TraQ | - |
| CR208_RS23945 () | 22234..22632 | + | 399 | WP_021293311.1 | hypothetical protein | - |
| CR208_RS23950 () | 22689..22940 | + | 252 | WP_021292797.1 | hypothetical protein | - |
| CR208_RS23955 () | 22855..23673 | + | 819 | WP_148935988.1 | conjugal transfer protein TraT | - |
| CR208_RS23960 () | 23728..24087 | + | 360 | WP_000380400.1 | hypothetical protein | - |
| CR208_RS23965 () | 24087..24467 | + | 381 | WP_021292799.1 | hypothetical protein | - |
| CR208_RS23970 () | 24643..27687 | + | 3045 | WP_001024758.1 | conjugal transfer protein | - |
| CR208_RS23975 () | 27687..28304 | + | 618 | WP_000286857.1 | hypothetical protein | - |
| CR208_RS23980 () | 28265..29470 | + | 1206 | WP_021293310.1 | conjugal transfer protein TraW | - |
| CR208_RS23985 () | 29467..30036 | + | 570 | WP_000650755.1 | conjugal transfer protein TraX | - |
| CR208_RS23990 () | 30109..32268 | + | 2160 | WP_040118366.1 | DotA/TraY family protein | - |
| CR208_RS23995 () | 32350..32997 | + | 648 | WP_001563237.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| CR208_RS24000 () | 33153..33314 | + | 162 | WP_001138649.1 | hypothetical protein | - |
| CR208_RS24005 () | 33311..33463 | - | 153 | WP_001367784.1 | Hok/Gef family protein | - |
| CR208_RS24010 () | 33797..34039 | + | 243 | WP_000064387.1 | hypothetical protein | - |
| CR208_RS24015 () | 34132..35667 | - | 1536 | WP_001367813.1 | phosphoethanolamine transferase | - |
| CR208_RS24020 () | 35867..36322 | - | 456 | WP_021292801.1 | DUF2569 family protein | - |
| CR208_RS24025 () | 36410..37033 | - | 624 | WP_001158019.1 | hypothetical protein | - |
| CR208_RS24030 () | 37182..37685 | + | 504 | WP_021293322.1 | thermonuclease family protein | - |
| CR208_RS24035 () | 38048..42127 | + | 4080 | WP_040118367.1 | Serine protease SepA autotransporter | VF |
| CR208_RS24040 () | 42289..42498 | - | 210 | WP_000855713.1 | hypothetical protein | - |
| CR208_RS24050 () | 42632..42997 | + | 366 | WP_040118368.1 | hypothetical protein | - |
| CR208_RS24055 () | 43007..43198 | + | 192 | WP_000264909.1 | hypothetical protein | - |
| CR208_RS24060 () | 43229..43540 | + | 312 | WP_029365223.1 | hypothetical protein | - |
| CR208_RS24070 () | 44315..45640 | + | 1326 | WP_040118369.1 | IncI1-type conjugal transfer protein TrbA | - |
| CR208_RS24075 () | 45637..46755 | + | 1119 | WP_001597028.1 | DsbC family protein | - |
| CR208_RS24080 () | 46736..49039 | + | 2304 | WP_000077655.1 | TraM recognition domain-containing protein | - |
| CR208_RS24085 () | 49165..49467 | + | 303 | WP_000334995.1 | hypothetical protein | - |
| CR208_RS24090 () | 49565..49996 | - | 432 | WP_001335086.1 | hypothetical protein | - |
| CR208_RS24095 () | 50064..52775 | - | 2712 | WP_011310099.1 | Protein TraI | Relaxase |
| CR208_RS24100 () | 52787..53119 | - | 333 | WP_001291058.1 | hypothetical protein | - |
| CR208_RS24105 () | 53352..53687 | + | 336 | WP_000157095.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| CR208_RS24110 () | 53773..54621 | - | 849 | WP_021292934.1 | DUF4942 domain-containing protein | - |
| CR208_RS24800 () | 55038..55358 | - | 321 | WP_021292935.1 | hypothetical protein | - |
| CR208_RS24125 () | 55355..55546 | - | 192 | WP_021292936.1 | hypothetical protein | - |
| CR208_RS24130 () | 55546..55965 | - | 420 | WP_000271737.1 | DUF1380 family protein | - |
| CR208_RS24135 () | 56012..56314 | - | 303 | WP_077776154.1 | antirestriction protein | - |
| CR208_RS24145 () | 56852..57628 | - | 777 | WP_024177483.1 | hypothetical protein | - |
| CR208_RS24150 () | 57679..58113 | - | 435 | WP_000274460.1 | DUF1380 family protein | - |
| CR208_RS24155 () | 58127..58348 | - | 222 | WP_001104895.1 | hypothetical protein | - |
| CR208_RS24160 () | 58349..59032 | - | 684 | WP_000086114.1 | DNA methylase | - |
| CR208_RS24165 () | 59313..60332 | - | 1020 | WP_000878014.1 | IS110 family transposase ISEc11 | Transposase |
| CR208_RS24170 () | 60548..60860 | - | 313 | Protein_65 | hypothetical protein | - |
| CR208_RS24175 () | 60857..61759 | - | 903 | WP_077629773.1 | DUF1281 domain-containing protein | - |
| CR208_RS24180 () | 62035..62283 | + | 249 | WP_000618108.1 | DinI-like family protein | - |
| CR208_RS24185 () | 62280..62717 | + | 438 | WP_021293182.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CR208_RS24190 () | 62717..63987 | + | 1271 | Protein_69 | Y-family DNA polymerase | - |
| CR208_RS24195 () | 64167..64793 | + | 627 | WP_000587689.1 | ParA family plasmid-partitioning AAA ATPase | - |
| CR208_RS24900 () | 64790..65092 | + | 303 | WP_001245884.1 | hypothetical protein | - |
| CR208_RS25005 () | 65481..65732 | + | 252 | WP_031322317.1 | hypothetical protein | - |
| CR208_RS24215 () | 65732..66322 | + | 591 | WP_000194574.1 | hypothetical protein | - |
| CR208_RS24220 () | 66342..66689 | - | 348 | WP_000142449.1 | hypothetical protein | - |
| CR208_RS24225 () | 66808..67155 | + | 348 | WP_000762580.1 | hypothetical protein | - |
| CR208_RS24230 () | 67173..69053 | - | 1881 | WP_001283354.1 | colicin | - |
| CR208_RS24235 () | 69332..69997 | - | 666 | WP_000448923.1 | hypothetical protein | - |
| CR208_RS24240 () | 70020..70229 | - | 210 | Protein_78 | IS21 family transposase IS21 | Transposase |
| CR208_RS24250 () | 70726..72699 | + | 1974 | WP_024199761.1 | Hemin receptor | VF |
| CR208_RS24255 () | 72718..73509 | + | 792 | WP_000977390.1 | DUF4198 domain-containing protein | - |
| CR208_RS24265 () | 74014..74439 | + | 426 | WP_021293190.1 | IS66 family transposase ISEc23 | Transposase |
| CR208_RS24270 () | 74436..74786 | + | 351 | WP_000624677.1 | IS66 family transposase IS682 | Transposase |
| CR208_RS24275 () | 74817..76409 | + | 1593 | WP_040118371.1 | IS66 family transposase ISEc47 | Transposase |
| CR208_RS24280 () | 76439..76612 | + | 174 | Protein_84 | DUF4113 domain-containing protein | - |
| CR208_RS24285 () | 76614..77030 | - | 417 | WP_001278818.1 | plasmid partitioning/stability family protein | - |
| CR208_RS24290 () | 77023..78003 | - | 981 | WP_000688510.1 | plasmid segregation protein ParM | - |
| CR208_RS24295 () | 78418..78726 | - | 309 | WP_000030199.1 | hypothetical protein | - |
| CR208_RS24300 () | 78813..79457 | - | 645 | WP_001144036.1 | ParA family protein | - |
| CR208_RS24305 () | 79638..80444 | - | 807 | WP_000016966.1 | site-specific integrase | - |
| CR208_RS24310 () | 80445..80750 | - | 306 | WP_021293254.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| CR208_RS24315 () | 80752..80970 | - | 219 | WP_000813639.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| CR208_RS24320 () | 81566..81826 | + | 261 | WP_000343102.1 | hypothetical protein | - |
| CR208_RS24325 () | 81823..82413 | + | 591 | WP_021293255.1 | hypothetical protein | - |
| CR208_RS24330 () | 82431..82778 | - | 348 | WP_033817147.1 | hypothetical protein | - |
| CR208_RS24335 () | 82907..83242 | + | 336 | WP_021292998.1 | colicin transporter | - |
| CR208_RS24340 () | 83249..83619 | - | 371 | Protein_96 | colicin | - |
| CR208_RS24345 () | 83679..84410 | - | 732 | WP_000850413.1 | complement resistance protein TraT | - |
| CR208_RS24905 () | 84687..84797 | - | 111 | Protein_98 | IS481 family transposase | - |
| CR208_RS25010 () | 84801..85015 | - | 215 | Protein_99 | hypothetical protein | - |
| CR208_RS24365 () | 85581..86558 | + | 978 | WP_024199652.1 | RepB family plasmid replication initiator protein | - |
| CR208_RS24370 () | 86786..87068 | - | 283 | Protein_101 | ISL3 family transposase ISEc53 | Transposase |
| CR208_RS24375 () | 87225..87455 | - | 231 | WP_040118372.1 | hypothetical protein | - |
| CR208_RS24385 () | 88909..89403 | - | 495 | WP_021293003.1 | Transcriptional repressor MprA | VF |
| CR208_RS24390 () | 89524..90963 | - | 1440 | WP_021293303.1 | Hemolysin secretion protein D, chromosomal | VF |
| CR208_RS24395 () | 90967..93087 | - | 2121 | WP_072094473.1 | Alpha-hemolysin translocation ATP-binding protein HlyB | VF |
| CR208_RS24400 () | 93137..96133 | - | 2997 | WP_021293304.1 | Hemolysin, chromosomal | VF |
| CR208_RS24405 () | 96135..96650 | - | 516 | WP_001365635.1 | RTX-I toxin-activating lysine-acyltransferase ApxIC | VF |
| CR208_RS24415 () | 97078..97881 | - | 804 | WP_040118373.1 | Outer membrane protein A | VF |
| CR208_RS24420 () | 97906..102234 | - | 4329 | WP_024199654.1 | Autotransporter adhesin SadA | VF |
| CR208_RS24425 () | 102251..102532 | - | 282 | WP_040118374.1 | Major pilu subunit operon regulatory protein PapB | VF |
| CR208_RS24430 () | 103628..105184 | + | 1557 | WP_040118375.1 | L-lactate permease | - |
| CR208_RS24435 () | 105235..105954 | + | 720 | WP_001102093.1 | (Fe-S)-binding protein | - |
| CR208_RS24440 () | 105965..107380 | + | 1416 | WP_000054160.1 | iron-sulfur cluster-binding protein | - |
| CR208_RS24445 () | 107385..108083 | + | 699 | WP_021293086.1 | lactate utilization protein C | - |
| CR208_RS24450 () | 108427..108891 | - | 465 | WP_077787444.1 | IS3 family transposase ISEcB1 | Transposase |
| CR208_RS24455 () | 109007..109318 | - | 312 | WP_000203483.1 | hypothetical protein | - |
| CR208_RS24460 () | 109346..109537 | - | 192 | WP_000264906.1 | hypothetical protein | - |
| CR208_RS24465 () | 109547..109912 | - | 366 | WP_001379349.1 | hypothetical protein | - |
| CR208_RS24475 () | 110046..110255 | + | 210 | WP_000855713.1 | hypothetical protein | - |
| CR208_RS24480 () | 110417..114319 | - | 3903 | WP_040118376.1 | Serine protease EspP | VF |
| CR208_RS24485 () | 114699..115202 | - | 504 | WP_021293446.1 | thermonuclease family protein | - |
| CR208_RS24490 () | 115361..116038 | + | 678 | Protein_123 | DNA-binding protein | - |
| CR208_RS24500 () | 116528..116848 | - | 321 | WP_000220092.1 | hypothetical protein | - |
| CR208_RS24805 () | 118151..118300 | - | 150 | WP_000539306.1 | hypothetical protein | - |
| CR208_RS24510 () | 118566..119948 | - | 1383 | WP_021293450.1 | autoagglutinating adhesin Saa | - |
| CR208_RS24910 () | 120202..120291 | + | 90 | Protein_128 | transposase | - |
| CR208_RS24520 () | 120358..121520 | + | 1163 | WP_096780418.1 | IS3 family transposase IS3 | Transposase |
| CR208_RS24525 () | 121865..122044 | + | 180 | Protein_130 | IS3 family transposase | - |
| CR208_RS24535 () | 122352..124439 | + | 2088 | WP_001223214.1 | bifunctional siderophore receptor/adhesin Iha | - |
| CR208_RS24540 () | 124700..125122 | - | 423 | WP_001212725.1 | Exc2 family lipoprotein | - |
| CR208_RS24545 () | 125606..126031 | + | 426 | WP_021293190.1 | IS66 family transposase ISEc23 | Transposase |
| CR208_RS24550 () | 126028..126378 | + | 351 | WP_000624677.1 | IS66 family transposase IS682 | Transposase |
| CR208_RS24555 () | 126409..128001 | + | 1593 | WP_040118371.1 | IS66 family transposase ISEc47 | Transposase |
| CR208_RS24560 () | 128033..128158 | - | 126 | Protein_136 | IS110 family transposase | - |
| CR208_RS24565 () | 128220..128408 | + | 189 | Protein_137 | IS66 family transposase ISEc47 | Transposase |
| CR208_RS24575 () | 128692..129117 | - | 426 | WP_001373081.1 | subtilase AB5 cytotoxin subunit B | - |
| CR208_RS24580 () | 129134..130177 | - | 1044 | WP_000912970.1 | subtilase AB5 cytotoxin subunit A | - |
| CR208_RS24585 () | 130231..131195 | - | 965 | Protein_140 | transposase | - |
| CR208_RS24590 () | 131226..131574 | - | 349 | Protein_141 | IS66 family transposase IS682 | Transposase |
| CR208_RS24595 () | 131571..131996 | - | 426 | WP_021293235.1 | IS66 family transposase IS682 | Transposase |
| CR208_RS24605 () | 132301..132486 | - | 186 | WP_071531845.1 | hypothetical protein | - |
| CR208_RS24610 () | 132486..133784 | - | 1299 | Protein_144 | VENN motif pre-toxin domain-containing protein | - |
| CR208_RS24615 () | 134041..134214 | + | 174 | Protein_145 | Tn3 family transposase | - |
| CR208_RS24620 () | 134411..135404 | + | 994 | Protein_146 | IS110 family transposase IS5075 | Transposase |
| CR208_RS24625 () | 135833..136093 | - | 261 | WP_000038919.1 | hypothetical protein | - |
| CR208_RS24630 () | 136713..145526 | - | 8814 | Protein_148 | tRNA nuclease CdiA | VF |
| CR208_RS24635 () | 145539..147305 | - | 1767 | WP_021292772.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| CR208_RS24645 () | 147920..148159 | - | 240 | WP_000859017.1 | MarR family transcriptional regulator | - |
| CR208_RS25015 () | 148172..148431 | - | 260 | Protein_151 | hypothetical protein | - |
| CR208_RS24665 () | 149123..149995 | - | 873 | WP_021292773.1 | incFII family plasmid replication initiator RepA | - |
| CR208_RS24680 () | 150698..151339 | + | 642 | WP_000335842.1 | transcription termination factor NusG | - |
| CR208_RS24685 () | 151480..152145 | + | 666 | WP_021292774.1 | hypothetical protein | - |
| CR208_RS24695 () | 152412..153032 | + | 621 | WP_000176497.1 | DUF1449 family protein | - |
| CR208_RS24700 () | 153059..154753 | + | 1695 | WP_000482663.1 | flotillin family protein | - |
| CR208_RS24705 () | 154834..155076 | + | 243 | WP_001271734.1 | PilI type IV pilus biogenesis protein | - |
| CR208_RS24710 () | 155192..155527 | + | 336 | WP_024199660.1 | hypothetical protein | - |
| CR208_RS24715 () | 156134..157021 | + | 888 | WP_096780419.1 | hypothetical protein | - |
| CR208_RS24720 () | 157014..157454 | - | 441 | WP_021292779.1 | hypothetical protein | - |
| CR208_RS24725 () | 157557..158624 | + | 1068 | WP_021293313.1 | hypothetical protein | VF |
| CR208_RS24730 () | 158629..159066 | + | 438 | WP_000539684.1 | type IV pilus biogenesis protein PilM | - |
| CR208_RS24735 () | 159097..160716 | + | 1620 | WP_001034998.1 | Outer membrane lipoprotein BfpB | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|