NZ_CP0234241..195692

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 195692 bp
Accession: NZ_CP023424        Location: 1..195692         Organism: Enterococcus faecium strain K60-39       Replicon: plasmid pTT39_p1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNX66_RS13985 () 1..1041 + 1041 WP_002326172.1 replication initiator protein A -
CNX66_RS13990 () 1865..2197 + 333 WP_002323647.1 hypothetical protein -
CNX66_RS13995 () 2816..3157 + 342 WP_002295674.1 DUF5406 domain-containing protein -
CNX66_RS14000 () 3394..4644 - 1251 WP_002287107.1 IS110 family transposase ISSpn10 Transposase
CNX66_RS14005 () 5054..5293 + 240 WP_002295673.1 hypothetical protein -
CNX66_RS14010 () 5360..5569 + 210 WP_002295672.1 hypothetical protein -
CNX66_RS14015 () 5629..6300 + 672 WP_002324491.1 class A sortase -
CNX66_RS14020 () 6353..8329 + 1977 WP_002326171.1 isopeptide-forming domain-containing fimbrial protein -
CNX66_RS14025 () 8344..9096 + 753 WP_096157791.1 hypothetical protein VF
CNX66_RS14030 () 9112..9873 + 762 WP_002302869.1 hypothetical protein -
CNX66_RS14035 () 9886..10146 + 261 WP_002302867.1 hypothetical protein -
CNX66_RS14040 () 10143..12233 + 2091 WP_002305225.1 isopeptide-forming domain-containing fimbrial protein -
CNX66_RS14045 () 12260..12724 + 465 WP_080474562.1 hypothetical protein -
CNX66_RS14050 () 12721..12963 + 243 WP_002305229.1 DUF5415 family protein -
CNX66_RS14055 () 12981..13283 + 303 WP_002295662.1 hypothetical protein -
CNX66_RS14060 () 13353..15416 + 2064 WP_002317430.1 hypothetical protein -
CNX66_RS14065 () 15416..18025 + 2610 WP_002305162.1 type IV secretory system conjugative DNA transfer family protein -
CNX66_RS14070 () 18022..19881 + 1860 Protein_17 hypothetical protein -
CNX66_RS14075 () 19947..21248 - 1302 WP_002302440.1 ISL3 family transposase ISEfa11 Transposase
CNX66_RS14080 () 21365..21895 + 531 Protein_19 hypothetical protein -
CNX66_RS14085 () 21947..22279 + 333 WP_002326876.1 hypothetical protein -
CNX66_RS14090 () 22280..22873 + 594 WP_002313112.1 hypothetical protein -
CNX66_RS14095 () 23036..24730 + 1695 WP_096157793.1 ATPase -
CNX66_RS14105 () 25418..27295 + 1878 WP_002305177.1 group II intron reverse transcriptase/maturase -
CNX66_RS14110 () 27426..27803 + 378 Protein_24 ATPase -
CNX66_RS14115 () 27803..29008 + 1206 WP_074394474.1 glucosaminidase domain-containing protein -
CNX66_RS14120 () 29024..29668 + 645 WP_060794172.1 hypothetical protein -
CNX66_RS14125 () 29679..30485 + 807 WP_060794173.1 hypothetical protein -
CNX66_RS14130 () 30507..30737 + 231 WP_025477554.1 hypothetical protein -
CNX66_RS14135 () 31283..31558 + 276 WP_002325546.1 hypothetical protein -
CNX66_RS14140 () 31600..32022 + 423 WP_060794174.1 hypothetical protein -
CNX66_RS14145 () 32041..33633 + 1593 WP_021109222.1 hypothetical protein Relaxase
CNX66_RS14150 () 33645..33980 + 336 WP_002310991.1 hypothetical protein -
CNX66_RS14155 () 34121..34315 + 195 WP_010726515.1 hypothetical protein -
CNX66_RS14160 () 34451..35701 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
CNX66_RS14165 () 36111..38483 + 2373 WP_060797393.1 hypothetical protein -
CNX66_RS14170 () 38544..40013 + 1470 WP_002313123.1 toprim domain-containing protein -
CNX66_RS14175 () 40024..42033 + 2010 WP_002303486.1 DNA topoisomerase III -
CNX66_RS15990 () 42149..42298 + 150 WP_002295632.1 hypothetical protein -
CNX66_RS14180 () 42379..42975 + 597 WP_002299811.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
CNX66_RS14185 () 42988..43887 + 900 WP_002301800.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CNX66_RS14190 () 43890..44021 + 132 WP_002301801.1 single-stranded DNA-binding protein -
CNX66_RS14195 () 44043..44375 + 333 WP_002305808.1 single-stranded DNA-binding protein -
CNX66_RS14200 () 44397..44654 + 258 WP_002295625.1 hypothetical protein -
CNX66_RS14205 () 44813..44935 - 123 WP_002295624.1 putative holin-like toxin -
CNX66_RS14210 () 45125..45349 + 225 WP_002305809.1 hypothetical protein -
CNX66_RS14220 () 45792..45998 + 207 WP_002305810.1 hypothetical protein -
CNX66_RS14225 () 45998..46249 + 252 WP_002300797.1 hypothetical protein -
CNX66_RS15995 () 46265..46420 + 156 WP_002300799.1 hypothetical protein -
CNX66_RS14230 () 46430..46702 + 273 WP_002300801.1 hypothetical protein -
CNX66_RS14240 () 47147..47326 + 180 WP_002300804.1 hypothetical protein -
CNX66_RS14245 () 47385..47741 + 357 WP_002311569.1 hypothetical protein -
CNX66_RS14255 () 48710..49663 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CNX66_RS14260 () 49784..50047 + 264 WP_002300807.1 uberolysin/carnocyclin family circular bacteriocin -
CNX66_RS14270 () 50419..51597 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CNX66_RS14275 () 51986..53932 + 1947 WP_002300833.1 PTS sugar transporter subunit IIA -
CNX66_RS14280 () 53935..54390 + 456 WP_002300835.1 PTS sugar transporter subunit IIA -
CNX66_RS14285 () 54404..55732 + 1329 WP_002300836.1 PTS galactitol transporter subunit IIC -
CNX66_RS14290 () 55766..56050 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
CNX66_RS14295 () 56052..56567 + 516 WP_002300840.1 YjbQ family protein -
CNX66_RS14300 () 56583..57245 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
CNX66_RS14305 () 57252..57824 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
CNX66_RS14310 () 58011..59531 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
CNX66_RS14315 () 59774..59959 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
CNX66_RS14320 () 59943..60125 - 183 WP_002300846.1 hypothetical protein -
CNX66_RS14325 () 60366..60584 + 219 Protein_65 IS256 family transposase ISLgar5 Transposase
CNX66_RS14330 () 61079..61678 + 600 WP_002301839.1 Tyrosine recombinase XerD VF
CNX66_RS14335 () 61742..62341 + 600 WP_002322465.1 bacteriophage abortive infection AbiH family protein -
CNX66_RS14340 () 62371..63022 - 652 Protein_68 IS6 family transposase IS1216V Transposase
CNX66_RS14345 () 63357..64229 - 873 WP_002292418.1 ROK family protein -
CNX66_RS14350 () 64493..66439 - 1947 WP_002293868.1 sucrose-specific PTS transporter subunit IIBC -
CNX66_RS14355 () 66624..68063 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
CNX66_RS14360 () 68065..69027 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
CNX66_RS14370 () 70866..71321 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
CNX66_RS14380 () 71586..71684 + 99 Protein_75 IS30 family transposase -
CNX66_RS14385 () 71907..72137 - 231 WP_002289255.1 resolvase -
CNX66_RS14390 () 72367..73185 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
CNX66_RS14395 () 73346..74035 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
CNX66_RS14400 () 74049..75551 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
CNX66_RS14405 () 75564..76040 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
CNX66_RS15855 () 76137..76247 - 111 Protein_81 transposase -
CNX66_RS14425 () 78818..79336 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
CNX66_RS14440 () 81412..82497 + 1086 WP_002301591.1 tyrosine recombinase XerS -
CNX66_RS14445 () 82605..83558 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CNX66_RS14450 () 83689..84939 - 1251 WP_002301126.1 PTS sugar transporter subunit IIC -
CNX66_RS14455 () 84958..85883 - 926 Protein_87 haloacid dehalogenase-like hydrolase -
CNX66_RS14460 () 85962..86957 - 996 WP_002301128.1 tagatose-bisphosphate aldolase -
CNX66_RS14465 () 86973..88142 - 1170 WP_002301130.1 SIS domain-containing protein -
CNX66_RS14470 () 88158..88892 - 735 WP_002301131.1 GntR family transcriptional regulator -
CNX66_RS14480 () 91393..92685 - 1293 WP_002301811.1 IS256 family transposase ISBsu2 Transposase
CNX66_RS14485 () 92959..93219 - 261 WP_002313174.1 hypothetical protein -
CNX66_RS14490 () 93470..94648 + 1179 WP_002346943.1 IS256 family transposase ISEf1 Transposase
CNX66_RS15860 () 95000..95209 + 210 WP_065305666.1 IS3 family transposase ISEfa8 Transposase
CNX66_RS14495 () 95181..95965 - 785 Protein_96 transposase -
CNX66_RS14500 () 96167..96562 - 396 WP_002287876.1 aspartate 1-decarboxylase -
CNX66_RS14505 () 96572..97420 - 849 WP_002287875.1 pantoate--beta-alanine ligase -
CNX66_RS14510 () 97435..98262 - 828 WP_002287874.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
CNX66_RS14515 () 98274..99134 - 861 WP_002349114.1 Rossmann-like and DUF2520 domain-containing protein -
CNX66_RS14520 () 99372..99857 + 486 Protein_101 IS256 family transposase ISEfa13 Transposase
CNX66_RS14525 () 99940..100134 + 195 WP_002285758.1 hypothetical protein -
CNX66_RS14530 () 100124..100489 + 366 WP_014387108.1 IS66 family transposase ISDeal1 Transposase
CNX66_RS14535 () 100578..102134 + 1557 WP_096157795.1 IS66 family transposase ISRob1 Transposase
CNX66_RS14540 () 102161..102355 + 195 WP_002285758.1 hypothetical protein -
CNX66_RS14545 () 102345..102698 + 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CNX66_RS14550 () 102800..104347 + 1548 WP_002299190.1 IS66 family transposase ISRob1 Transposase
CNX66_RS14555 () 104551..105246 + 696 Protein_108 IS256 family transposase ISEfa13 Transposase
CNX66_RS14560 () 105560..106240 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
CNX66_RS14565 () 106784..107956 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
CNX66_RS14575 () 108086..109525 - 1440 WP_001028141.1 Bifunctional AAC/APH ARG
CNX66_RS14580 () 109526..109918 - 393 WP_025189010.1 GNAT family N-acetyltransferase -
CNX66_RS14585 () 109902..111137 - 1236 Protein_113 Bifunctional AAC/APH ARG
CNX66_RS14590 () 111192..111368 - 177 Protein_114 IS6 family transposase -
CNX66_RS14595 () 111528..112565 - 1038 WP_002303110.1 IS3 family transposase ISSde10 Transposase
CNX66_RS14600 () 112562..113074 - 513 WP_002387940.1 IS3 family transposase ISPa31 Transposase
CNX66_RS14605 () 113144..113398 - 255 Protein_117 replication initiation protein -
CNX66_RS14610 () 113742..114422 - 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
CNX66_RS14615 () 114492..114872 + 381 Protein_119 IS6 family transposase IS1216V Transposase
CNX66_RS14620 () 114967..115518 + 552 WP_002303113.1 DUF334 domain-containing protein -
CNX66_RS16000 () 115813..115986 + 174 WP_010729368.1 hypothetical protein -
CNX66_RS14625 () 115986..116666 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
CNX66_RS14630 () 116926..117531 + 606 WP_002321606.1 Tn3 family transposase TnpR_ISPa40 Transposase
CNX66_RS14635 () 117576..117743 - 168 WP_000824191.1 hypothetical protein -
CNX66_RS14640 () 117777..118076 - 300 WP_000366408.1 BRCT domain-containing protein -
CNX66_RS14645 () 118117..118734 - 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
CNX66_RS14650 () 119059..119453 - 395 Protein_127 hypothetical protein -
CNX66_RS14655 () 119533..121884 - 2352 WP_000344083.1 DUF1906 domain-containing protein -
CNX66_RS14660 () 122009..122698 - 690 WP_000718009.1 hypothetical protein -
CNX66_RS14665 () 122712..123164 - 453 WP_000751236.1 hypothetical protein -
CNX66_RS14670 () 123295..123975 + 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
CNX66_RS14675 () 124046..125365 - 1320 WP_002300494.1 HAMP domain-containing histidine kinase -
CNX66_RS14680 () 125362..126015 - 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
CNX66_RS14690 () 126303..127577 + 1275 WP_010729371.1 ISL3 family transposase IS1476 Transposase
CNX66_RS14695 () 127632..129197 + 1566 WP_032494987.1 glutamine-hydrolyzing GMP synthase -
CNX66_RS14700 () 129617..130486 - 870 WP_010729372.1 ROK family protein -
CNX66_RS14705 () 130538..131530 - 993 WP_010729373.1 LacI family DNA-binding transcriptional regulator -
CNX66_RS14710 () 131707..133191 - 1485 WP_010729374.1 glycoside hydrolase family 32 protein -
CNX66_RS14715 () 133192..134799 - 1608 WP_010729375.1 ABC transporter substrate-binding protein -
CNX66_RS14720 () 134848..135732 - 885 WP_005230433.1 carbohydrate ABC transporter permease -
CNX66_RS14725 () 135748..136740 - 993 WP_005233042.1 sugar ABC transporter permease -
CNX66_RS14730 () 137364..137810 - 447 WP_025481119.1 hypothetical protein -
CNX66_RS14735 () 138405..138755 + 351 WP_010729377.1 hypothetical protein -
CNX66_RS14740 () 138960..139808 + 849 WP_010729378.1 rep protein -
CNX66_RS14745 () 139855..140049 + 195 WP_002351139.1 DUF3173 domain-containing protein -
CNX66_RS14750 () 140052..141254 + 1203 WP_010729379.1 site-specific integrase -
CNX66_RS14755 () 141480..141674 + 195 WP_002285758.1 hypothetical protein -
CNX66_RS14760 () 141664..142017 + 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CNX66_RS14765 () 142119..143666 + 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
CNX66_RS14770 () 144058..144990 - 933 WP_002288609.1 hypothetical protein -
CNX66_RS14775 () 145030..146691 - 1662 WP_002288608.1 O-GlcNAcase NagJ VF
CNX66_RS14780 () 146688..149669 - 2982 WP_002305865.1 glycoside hydrolase family 42 -
CNX66_RS14785 () 149797..151710 - 1914 WP_002304880.1 beta-N-acetylhexosaminidase -
CNX66_RS14790 () 151740..152351 - 612 WP_002304878.1 DUF624 domain-containing protein -
CNX66_RS14795 () 152402..153873 - 1472 Protein_155 extracellular solute-binding protein -
CNX66_RS14800 () 153897..154808 - 912 WP_002289655.1 carbohydrate ABC transporter permease -
CNX66_RS14805 () 154820..155758 - 939 WP_002304874.1 sugar ABC transporter permease -
CNX66_RS14810 () 155987..157561 + 1575 WP_002340467.1 histidine kinase -
CNX66_RS14815 () 157539..158267 + 729 WP_002302980.1 helix-turn-helix domain-containing protein -
CNX66_RS14820 () 158650..159924 - 1275 WP_010729381.1 ISL3 family transposase IS1476 Transposase
CNX66_RS14825 () 160125..161339 + 1215 Protein_161 ISL3 family transposase ISEfa11 Transposase
CNX66_RS14830 () 161518..161847 - 330 WP_002299919.1 type II toxin-antitoxin system PemK/MazF family toxin -
CNX66_RS14835 () 161837..162109 - 273 WP_002299921.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
CNX66_RS14840 () 162560..163363 - 804 WP_002299923.1 metallophosphoesterase -
CNX66_RS14845 () 163341..164465 - 1125 WP_002299925.1 Maltose/maltodextrin import ATP-binding protein MalK VF
CNX66_RS14850 () 164481..165296 - 816 WP_002299926.1 carbohydrate ABC transporter permease -
CNX66_RS14855 () 165286..166176 - 891 WP_014748799.1 sugar ABC transporter permease -
CNX66_RS14860 () 166243..167532 - 1290 WP_002299928.1 ABC transporter substrate-binding protein -
CNX66_RS14865 () 167760..168404 - 645 Protein_169 glycerophosphodiester phosphodiesterase -
CNX66_RS14875 () 168881..170359 - 1479 WP_010729383.1 IS1182 family transposase ISEfa7 Transposase
CNX66_RS14880 () 170349..171548 - 1200 WP_010729384.1 IS256 family transposase ISBsu2 Transposase
CNX66_RS14885 () 171678..173054 - 1377 WP_002298085.1 ABC transporter permease -
CNX66_RS14890 () 173054..173710 - 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
CNX66_RS14895 () 173720..174997 - 1278 WP_002301194.1 ABC transporter permease -
CNX66_RS14900 () 175016..175171 - 156 Protein_175 4Fe-4S binding protein -
CNX66_RS14905 () 175247..176409 + 1163 WP_087121905.1 IS3 family transposase ISEfa8 Transposase
CNX66_RS14910 () 176439..176888 - 450 WP_010729386.1 TlpA family protein disulfide reductase -
CNX66_RS16005 () 177044..177586 - 543 WP_002298088.1 hypothetical protein -
CNX66_RS14925 () 177861..178504 + 644 Protein_179 transposase -
CNX66_RS14930 () 178580..179260 + 681 WP_002331383.1 IS6 family transposase IS1216E Transposase
CNX66_RS14935 () 179315..179671 - 357 Protein_181 hypothetical protein -
CNX66_RS14940 () 179931..180478 - 548 Protein_182 hypothetical protein -
CNX66_RS14945 () 180479..181336 - 858 WP_002292680.1 AAA family ATPase -
CNX66_RS14950 () 181622..181908 - 287 Protein_184 type II toxin-antitoxin system RelE/ParE family toxin -
CNX66_RS14955 () 181898..182227 - 330 WP_002292678.1 AbrB family transcriptional regulator -
CNX66_RS14960 () 182304..182576 - 273 WP_002314366.1 Txe/YoeB family addiction module toxin Toxin Detail
CNX66_RS14965 () 182576..182839 - 264 WP_002297422.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
CNX66_RS14970 () 183073..183981 + 909 Protein_188 IS982 family transposase ISEfm1 Transposase
CNX66_RS14975 () 183984..185159 - 1176 WP_002336205.1 MFS transporter -
CNX66_RS14980 () 185162..187411 - 2250 WP_002314387.1 alpha-galactosidase -
CNX66_RS14985 () 187508..188362 - 855 WP_002338109.1 AraC family transcriptional regulator -
CNX66_RS14990 () 188444..189352 - 909 Protein_192 IS982 family transposase ISEfm1 Transposase
CNX66_RS14995 () 189446..190381 - 936 WP_002323400.1 hypothetical protein -
CNX66_RS15000 () 190940..191257 - 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
CNX66_RS15005 () 191258..191512 - 255 WP_002323399.1 hypothetical protein -
CNX66_RS15010 () 191871..192275 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
CNX66_RS15015 () 192292..193440 + 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
CNX66_RS15020 () 193663..193881 - 219 Protein_198 type II toxin-antitoxin system RelE/ParE family toxin -
CNX66_RS15025 () 194147..194341 - 195 WP_002348857.1 hypothetical protein -
CNX66_RS16010 () 194441..194527 - 87 Protein_200 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance