MGE detailed information
MGE type: Conjugative plasmid MGE length: 123289 bp
Accession: NZ_CP023378 Location: 1..123289 Organism: Escherichia coli strain 127 Replicon: plasmid p123
Accession: NZ_CP023378 Location: 1..123289 Organism: Escherichia coli strain 127 Replicon: plasmid p123
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CNQ50_RS25000 () | 1..447 | + | 447 | Protein_1 | incFII family plasmid replication initiator RepA | - |
| CNQ50_RS25005 () | 393..875 | - | 483 | Protein_2 | VENN motif pre-toxin domain-containing protein | - |
| CNQ50_RS25010 () | 1768..2988 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| CNQ50_RS25015 () | 2999..3910 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| CNQ50_RS25020 () | 3995..4999 | + | 1005 | WP_000154544.1 | Ornithine carbamoyltransferase | VF |
| CNQ50_RS25025 () | 5047..6450 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| CNQ50_RS25030 () | 6531..7010 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| CNQ50_RS25035 () | 7074..7415 | - | 342 | Protein_8 | transposase | - |
| CNQ50_RS25040 () | 7367..7588 | - | 222 | WP_000080217.1 | hypothetical protein | - |
| CNQ50_RS25045 () | 7619..7969 | - | 351 | WP_000624725.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| CNQ50_RS25050 () | 7966..8328 | - | 363 | WP_059330006.1 | IS66 family transposase ISEc23 | Transposase |
| CNQ50_RS25055 () | 8437..9130 | - | 694 | Protein_12 | IS1 family transposase | - |
| CNQ50_RS25065 () | 9163..9741 | + | 579 | WP_032147503.1 | DUF2726 domain-containing protein | - |
| CNQ50_RS25070 () | 10154..10507 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| CNQ50_RS25075 () | 10979..12001 | - | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| CNQ50_RS25085 () | 12406..12663 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| CNQ50_RS25095 () | 12899..12973 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| CNQ50_RS25100 () | 12966..13823 | + | 858 | WP_000130948.1 | incFII family plasmid replication initiator RepA | - |
| CNQ50_RS28200 () | 14524..14664 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| CNQ50_RS25110 () | 14762..15415 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| CNQ50_RS27990 () | 15508..15765 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| CNQ50_RS25115 () | 15698..16099 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| CNQ50_RS25125 () | 16348..16763 | + | 416 | Protein_23 | IS1 family transposase | - |
| CNQ50_RS25130 () | 16799..17344 | - | 546 | Protein_24 | Tn3 family transposase TnpA_Tn3 | Transposase |
| CNQ50_RS25135 () | 17410..18114 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CNQ50_RS25140 () | 18314..18517 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| CNQ50_RS25150 () | 18645..19484 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| CNQ50_RS25155 () | 19478..19825 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| CNQ50_RS25160 () | 20031..20819 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| CNQ50_RS25165 () | 20950..21423 | - | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| CNQ50_RS25170 () | 21581..22261 | + | 681 | Protein_31 | IS91 family transposase ISAzo26 | Transposase |
| CNQ50_RS25180 () | 22326..23030 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CNQ50_RS25185 () | 23220..24035 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| CNQ50_RS25190 () | 24186..24890 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CNQ50_RS25200 () | 24951..25787 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| CNQ50_RS25205 () | 25787..26590 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| CNQ50_RS25210 () | 26651..27466 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| CNQ50_RS25220 () | 27774..28625 | - | 852 | WP_000240536.1 | replication protein | - |
| CNQ50_RS25225 () | 28612..29331 | - | 720 | Protein_39 | AAA family ATPase | - |
| CNQ50_RS25235 () | 29381..30085 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| CNQ50_RS25240 () | 30149..30820 | + | 672 | Protein_41 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| CNQ50_RS25245 () | 31045..31686 | - | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| CNQ50_RS25250 () | 31926..32246 | - | 321 | Protein_43 | IS1380 family transposase | - |
| CNQ50_RS25255 () | 32259..32819 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| CNQ50_RS25260 () | 32822..35788 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| CNQ50_RS25265 () | 35855..36232 | + | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| CNQ50_RS25270 () | 36433..37092 | - | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| CNQ50_RS25285 () | 37371..38068 | + | 698 | Protein_48 | IS1 family transposase | - |
| CNQ50_RS25295 () | 38643..38950 | + | 308 | Protein_49 | type II toxin-antitoxin system ParD family antitoxin | - |
| CNQ50_RS25305 () | 39293..39475 | + | 183 | WP_042065278.1 | hypothetical protein | - |
| CNQ50_RS25310 () | 39596..40336 | + | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| CNQ50_RS25315 () | 40621..41598 | - | 978 | WP_096038024.1 | RepB family plasmid replication initiator protein | - |
| CNQ50_RS28205 () | 42719..43114 | + | 396 | WP_175188304.1 | hypothetical protein | - |
| CNQ50_RS25335 () | 43601..44298 | + | 698 | Protein_54 | IS1 family transposase | - |
| CNQ50_RS25340 () | 44315..44881 | - | 567 | Protein_55 | hypothetical protein | - |
| CNQ50_RS25345 () | 44885..45880 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| CNQ50_RS25350 () | 46345..48483 | + | 2139 | WP_000350635.1 | AAA family ATPase | - |
| CNQ50_RS25355 () | 48645..49061 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| CNQ50_RS25360 () | 49058..49288 | - | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| CNQ50_RS25370 () | 49595..52714 | + | 3120 | WP_001553851.1 | hypothetical protein | - |
| CNQ50_RS25375 () | 52977..54110 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| CNQ50_RS25380 () | 54130..54414 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| CNQ50_RS25385 () | 54411..54608 | - | 198 | WP_000215657.1 | hypothetical protein | - |
| CNQ50_RS25390 () | 55242..55460 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| CNQ50_RS25395 () | 55462..55767 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| CNQ50_RS25400 () | 55768..56574 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| CNQ50_RS25405 () | 57348..58103 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| CNQ50_RS25410 () | 58691..59857 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| CNQ50_RS25415 () | 59857..60828 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| CNQ50_RS25430 () | 61695..62597 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| CNQ50_RS25435 () | 62601..62905 | + | 305 | Protein_71 | hypothetical protein | - |
| CNQ50_RS25440 () | 62982..63665 | + | 684 | WP_000086185.1 | DNA methylase | - |
| CNQ50_RS25445 () | 63666..63887 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| CNQ50_RS25450 () | 63901..64335 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| CNQ50_RS27995 () | 64386..65162 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| CNQ50_RS25465 () | 65702..66003 | + | 302 | Protein_76 | antirestriction protein | - |
| CNQ50_RS25470 () | 66050..66472 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| CNQ50_RS28210 () | 66629..67178 | - | 550 | Protein_78 | hypothetical protein | - |
| CNQ50_RS25495 () | 67692..67922 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| CNQ50_RS25500 () | 67974..69335 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| CNQ50_RS25505 () | 69383..69946 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| CNQ50_RS25510 () | 69972..70208 | + | 237 | WP_032153960.1 | hypothetical protein | - |
| CNQ50_RS25525 () | 71309..71878 | - | 570 | WP_123863258.1 | hypothetical protein | - |
| CNQ50_RS25540 () | 73182..73940 | + | 759 | Protein_85 | site-specific integrase | - |
| CNQ50_RS25545 () | 74098..75108 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| CNQ50_RS25550 () | 75204..77330 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| CNQ50_RS25555 () | 77393..78670 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| CNQ50_RS25560 () | 78667..80100 | + | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| CNQ50_RS25565 () | 80295..81689 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
| CNQ50_RS25570 () | 81935..82039 | - | 105 | Protein_91 | thiosulfate reductase cytochrome B subunit | - |
| CNQ50_RS25580 () | 82096..82789 | + | 694 | Protein_92 | IS1 family transposase | - |
| CNQ50_RS25585 () | 82805..83428 | + | 624 | WP_000912556.1 | potassium channel family protein | - |
| CNQ50_RS25590 () | 83513..83764 | + | 252 | Protein_94 | iron-containing alcohol dehydrogenase | - |
| CNQ50_RS25595 () | 84053..84370 | - | 318 | Protein_95 | IS110 family transposase | - |
| CNQ50_RS25600 () | 84525..84630 | + | 106 | Protein_96 | plasmid SOS inhibition protein A | - |
| - () | 84599..84797 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 84599..84797 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 84599..84797 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 84599..84797 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| CNQ50_RS25605 () | 84862..85020 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| CNQ50_RS28215 () | 85688..85894 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| CNQ50_RS25620 () | 85919..86206 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| CNQ50_RS25625 () | 86325..87146 | + | 822 | WP_001234465.1 | DUF945 domain-containing protein | - |
| CNQ50_RS25630 () | 87442..88014 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
| CNQ50_RS25635 () | 88384..88767 | + | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| CNQ50_RS25640 () | 88958..89605 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| CNQ50_RS25645 () | 89741..89956 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| CNQ50_RS25650 () | 89999..90364 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| CNQ50_RS25655 () | 90379..90690 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| CNQ50_RS25660 () | 90712..91278 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| CNQ50_RS25665 () | 91289..91993 | + | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| CNQ50_RS25670 () | 91993..93420 | + | 1428 | WP_001553836.1 | conjugal transfer protein TraB | - |
| CNQ50_RS25675 () | 93410..94000 | + | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| CNQ50_RS28010 () | 93987..94124 | + | 138 | WP_001553834.1 | conjugal transfer protein TrbD | - |
| CNQ50_RS25680 () | 94146..94307 | + | 162 | WP_000741714.1 | conjugal transfer protein TrbD | - |
| CNQ50_RS25685 () | 94300..94551 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| CNQ50_RS25690 () | 94548..95063 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CNQ50_RS25695 () | 95198..95419 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| CNQ50_RS25700 () | 95579..98206 | + | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| CNQ50_RS25705 () | 98203..98589 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| CNQ50_RS25710 () | 98586..99218 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| CNQ50_RS25715 () | 99215..100207 | + | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| CNQ50_RS25720 () | 100216..100854 | + | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| CNQ50_RS25725 () | 100851..102659 | + | 1809 | WP_001553831.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| CNQ50_RS25730 () | 102686..102943 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| CNQ50_RS25735 () | 102936..103679 | + | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| CNQ50_RS25740 () | 103693..104034 | + | 342 | WP_000556794.1 | conjugal transfer protein TrbA | - |
| CNQ50_RS25745 () | 104015..104350 | - | 336 | WP_000415571.1 | hypothetical protein | - |
| CNQ50_RS25750 () | 104431..104715 | + | 285 | WP_000624105.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| CNQ50_RS25755 () | 104702..105256 | + | 555 | WP_001553830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| CNQ50_RS25760 () | 105186..105559 | + | 374 | Protein_128 | P-type conjugative transfer protein TrbJ | - |
| CNQ50_RS25765 () | 105513..105905 | + | 393 | WP_001553828.1 | F-type conjugal transfer protein TrbF | - |
| CNQ50_RS25770 () | 105892..107265 | + | 1374 | WP_001553827.1 | conjugal transfer protein TraH | - |
| CNQ50_RS25775 () | 107262..110087 | + | 2826 | WP_001553826.1 | conjugal transfer mating pair stabilization protein TraG | - |
| CNQ50_RS25780 () | 110084..110539 | + | 456 | WP_001553825.1 | conjugal transfer entry exclusion protein TraS | - |
| CNQ50_RS25785 () | 110608..111339 | + | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| CNQ50_RS25790 () | 111591..113771 | + | 2181 | WP_001553824.1 | type IV conjugative transfer system coupling protein TraD | - |
| CNQ50_RS25795 () | 113771..119041 | + | 5271 | WP_001553822.1 | Multifunctional conjugation protein TraI | Relaxase |
| CNQ50_RS25800 () | 119061..119807 | + | 747 | WP_000205701.1 | conjugal transfer pilus acetylase TraX | - |
| CNQ50_RS25805 () | 119862..120422 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| CNQ50_RS25810 () | 120555..120767 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| CNQ50_RS25820 () | 121068..121770 | - | 703 | Protein_139 | IS1 family transposase | - |
| CNQ50_RS25830 () | 121871..122053 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - () | 122192..122253 | - | 62 | NuclAT_1 | - | - |
| - () | 122192..122253 | - | 62 | NuclAT_1 | - | - |
| - () | 122192..122253 | - | 62 | NuclAT_1 | - | - |
| - () | 122192..122253 | - | 62 | NuclAT_1 | - | - |
| CNQ50_RS25840 () | 122240..122446 | + | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | - |
| CNQ50_RS25845 () | 122730..122987 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|