MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 140072 bp
Accession: NZ_CP023165 Location: 3514536..3654607 Organism: Escherichia coli O22:H8 strain RM10809-3 Replicon: chromosome
Accession: NZ_CP023165 Location: 3514536..3654607 Organism: Escherichia coli O22:H8 strain RM10809-3 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CLC88_RS17945 () | 3509793..3510533 | - | 741 | WP_001367953.1 | porin family protein | - |
| CLC88_RS17950 () | 3510966..3512792 | + | 1827 | WP_001106666.1 | two-component system sensor histidine kinase AtoS | - |
| CLC88_RS17955 () | 3512789..3514174 | + | 1386 | WP_000125284.1 | acetoacetate metabolism transcriptional regulator AtoC | - |
| CLC88_RS17960 () | 3514370..3515032 | + | 663 | WP_000850528.1 | acetate CoA-transferase subunit alpha | - |
| CLC88_RS17965 () | 3515032..3515682 | + | 651 | WP_000339054.1 | acetate CoA-transferase subunit beta | - |
| CLC88_RS17970 () | 3515679..3517001 | + | 1323 | WP_000580275.1 | TIGR00366 family protein | - |
| CLC88_RS17975 () | 3517032..3518216 | + | 1185 | WP_000786522.1 | acetyl-CoA acetyltransferase | - |
| CLC88_RS17980 () | 3518626..3519282 | - | 657 | Protein_3390 | IS66 family transposase ISEc23 | Transposase |
| CLC88_RS17990 () | 3520371..3520550 | + | 180 | WP_072000282.1 | hypothetical protein | - |
| CLC88_RS17995 () | 3520602..3520795 | + | 194 | Protein_3392 | hypothetical protein | - |
| CLC88_RS18000 () | 3521597..3521933 | - | 337 | Protein_3393 | hypothetical protein | - |
| CLC88_RS18005 () | 3522603..3522824 | - | 222 | WP_000477612.1 | hypothetical protein | - |
| CLC88_RS18010 () | 3524278..3526364 | + | 2087 | Protein_3395 | Colicin I receptor | VF |
| CLC88_RS18015 () | 3526505..3526696 | - | 192 | Protein_3396 | IS256 family transposase ISEic2 | Transposase |
| CLC88_RS18020 () | 3526710..3528554 | - | 1845 | WP_000593011.1 | Vitamin B12 transporter BtuB | VF |
| CLC88_RS18025 () | 3529455..3529712 | - | 258 | WP_001032733.1 | hypothetical protein | - |
| CLC88_RS18030 () | 3529781..3531478 | - | 1698 | WP_000401036.1 | sulfatase | - |
| CLC88_RS18035 () | 3531573..3532709 | - | 1137 | WP_001228923.1 | Outer membrane porin protein OmpD | VF |
| CLC88_RS18040 () | 3533385..3533593 | + | 209 | Protein_3401 | IS66 family insertion sequence element accessory protein TnpB | - |
| CLC88_RS18045 () | 3533580..3533892 | + | 313 | Protein_3402 | IS66 family insertion sequence element accessory protein TnpB | - |
| CLC88_RS18050 () | 3534846..3535583 | + | 738 | Protein_3403 | AraC family transcriptional regulator | - |
| CLC88_RS18055 () | 3536483..3538186 | + | 1704 | WP_155705050.1 | Serine protease SepA autotransporter | VF |
| CLC88_RS18060 () | 3538213..3540573 | + | 2361 | WP_196497617.1 | Serine protease EspP | VF |
| CLC88_RS25770 () | 3541123..3541443 | + | 321 | WP_196497618.1 | hypothetical protein | - |
| CLC88_RS18070 () | 3541453..3541644 | + | 192 | WP_000264910.1 | hypothetical protein | - |
| CLC88_RS18075 () | 3541678..3541887 | + | 210 | WP_000323309.1 | hypothetical protein | - |
| CLC88_RS18080 () | 3541914..3542273 | - | 360 | Protein_3409 | IS66 family transposase ISCro1 | Transposase |
| CLC88_RS18085 () | 3542385..3543029 | - | 645 | WP_001378814.1 | hypothetical protein | - |
| CLC88_RS18090 () | 3543050..3543319 | - | 270 | WP_000226517.1 | PerC family transcriptional regulator | - |
| CLC88_RS18095 () | 3543398..3544036 | - | 639 | WP_000502848.1 | ParB N-terminal domain-containing protein | - |
| CLC88_RS18100 () | 3544021..3545253 | - | 1233 | WP_001285503.1 | phosphoadenosine phosphosulfate reductase | - |
| CLC88_RS18105 () | 3545753..3548434 | - | 2682 | WP_196497613.1 | DUF2726 domain-containing protein | - |
| CLC88_RS25775 () | 3548685..3548798 | - | 114 | WP_192815547.1 | HecB | - |
| CLC88_RS18110 () | 3548807..3549436 | - | 630 | WP_192815546.1 | hypothetical protein | VF |
| CLC88_RS18115 () | 3549921..3551666 | - | 1746 | WP_050864088.1 | AAA family ATPase | - |
| CLC88_RS18120 () | 3551844..3552419 | - | 576 | WP_000737515.1 | Attachment invasion locus protein | VF |
| CLC88_RS18125 () | 3552963..3553205 | - | 243 | WP_000993065.1 | hypothetical protein | - |
| CLC88_RS18130 () | 3553212..3553484 | - | 273 | WP_000906735.1 | hypothetical protein | - |
| CLC88_RS18135 () | 3553619..3553894 | - | 276 | WP_000549471.1 | hypothetical protein | - |
| CLC88_RS18140 () | 3553923..3554106 | + | 184 | Protein_3422 | transposase domain-containing protein | - |
| CLC88_RS18145 () | 3554148..3554675 | - | 528 | WP_000182867.1 | hypothetical protein | - |
| CLC88_RS18150 () | 3555107..3556640 | - | 1534 | Protein_3424 | IS3 family transposase | - |
| CLC88_RS18155 () | 3557575..3566517 | - | 8943 | WP_155705054.1 | Toxin CdiA | VF |
| CLC88_RS18160 () | 3566533..3567060 | - | 528 | WP_001243916.1 | Leukotoxin-activating lysine-acyltransferase LtxC | VF |
| CLC88_RS18165 () | 3567070..3568722 | - | 1653 | WP_062856003.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| CLC88_RS18170 () | 3569398..3569589 | + | 192 | WP_001287885.1 | DUF4222 domain-containing protein | - |
| CLC88_RS18175 () | 3569642..3569875 | - | 234 | WP_000124190.1 | hypothetical protein | - |
| CLC88_RS18180 () | 3569971..3570594 | - | 624 | WP_001366001.1 | hypothetical protein | - |
| CLC88_RS18185 () | 3570683..3571180 | - | 498 | WP_021552435.1 | hypothetical protein | - |
| CLC88_RS18190 () | 3571530..3571937 | - | 408 | WP_179763680.1 | inovirus-type Gp2 protein | - |
| CLC88_RS18195 () | 3572124..3572321 | - | 198 | WP_000553835.1 | inovirus-type Gp2 protein | - |
| CLC88_RS18200 () | 3572570..3572995 | - | 426 | WP_001013306.1 | hypothetical protein | - |
| CLC88_RS18205 () | 3572992..3573375 | - | 384 | Protein_3435 | hypothetical protein | - |
| CLC88_RS18210 () | 3573636..3574205 | - | 570 | WP_000221484.1 | inovirus Gp2 family protein | - |
| CLC88_RS18215 () | 3574409..3574606 | + | 198 | WP_000236763.1 | hypothetical protein | - |
| CLC88_RS18220 () | 3574952..3575101 | - | 150 | WP_052904223.1 | hemolysin activation protein | - |
| CLC88_RS18225 () | 3575853..3576059 | + | 207 | WP_000632607.1 | AlpA family transcriptional regulator | - |
| CLC88_RS18230 () | 3576146..3576748 | + | 603 | WP_000804456.1 | hypothetical protein | - |
| CLC88_RS18235 () | 3577070..3578554 | - | 1485 | WP_001297234.1 | DUF3987 domain-containing protein | - |
| CLC88_RS18240 () | 3579784..3580655 | + | 872 | Protein_3442 | GTPase family protein | - |
| CLC88_RS18245 () | 3580983..3584102 | + | 3120 | WP_028985512.1 | autotransporter adhesin Ag43 | - |
| CLC88_RS18255 () | 3584223..3586163 | + | 1941 | Protein_3444 | hypothetical protein | - |
| CLC88_RS18260 () | 3586170..3586472 | + | 303 | Protein_3445 | IS3 family transposase ISEc31 | Transposase |
| CLC88_RS18265 () | 3586485..3587636 | - | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| CLC88_RS18270 () | 3587701..3588606 | + | 906 | Protein_3447 | IS3 family transposase ISCfr6 | Transposase |
| CLC88_RS18275 () | 3588617..3589051 | + | 435 | Protein_3448 | hypothetical protein | - |
| CLC88_RS18280 () | 3589127..3589582 | + | 456 | Protein_3449 | hypothetical protein | - |
| CLC88_RS18285 () | 3589661..3589894 | + | 234 | WP_001119729.1 | DUF905 family protein | - |
| CLC88_RS18290 () | 3589981..3590799 | + | 819 | WP_001234620.1 | DUF945 domain-containing protein | - |
| CLC88_RS18295 () | 3590854..3591339 | + | 486 | WP_000849591.1 | antirestriction protein | - |
| CLC88_RS18300 () | 3591355..3591831 | + | 477 | WP_001186726.1 | RadC family protein | - |
| CLC88_RS18305 () | 3591894..3592115 | + | 222 | WP_050864148.1 | DUF987 domain-containing protein | - |
| CLC88_RS18310 () | 3592278..3592652 | + | 375 | WP_001280952.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin Detail |
| CLC88_RS18315 () | 3592699..3593076 | + | 378 | WP_000854904.1 | TA system toxin CbtA family protein | Toxin Detail |
| CLC88_RS18320 () | 3593073..3593561 | + | 489 | WP_000779174.1 | hypothetical protein | - |
| CLC88_RS18325 () | 3593573..3593770 | + | 198 | WP_000839249.1 | DUF957 domain-containing protein | - |
| CLC88_RS18330 () | 3593855..3594697 | + | 843 | Protein_3459 | DUF4942 domain-containing protein | - |
| CLC88_RS18335 () | 3595040..3595576 | - | 537 | WP_000942786.1 | Type II secretion system protein M | VF |
| CLC88_RS18340 () | 3595578..3596756 | - | 1179 | WP_155705057.1 | Type II secretion system protein L | VF |
| CLC88_RS18345 () | 3596753..3597730 | - | 978 | WP_000633238.1 | Putative type II secretion system protein K | VF |
| CLC88_RS18350 () | 3597733..3598332 | - | 600 | WP_001255040.1 | Type II secretion system protein J | VF |
| CLC88_RS18355 () | 3598329..3598700 | - | 372 | WP_000820125.1 | Type II secretion system protein I | VF |
| CLC88_RS18360 () | 3598697..3599260 | - | 564 | WP_001115140.1 | Type II secretion system protein H | VF |
| CLC88_RS18365 () | 3599264..3599719 | - | 456 | WP_001087296.1 | Type II secretion system protein G | VF |
| CLC88_RS18370 () | 3599736..3600959 | - | 1224 | WP_001173448.1 | Type II secretion system protein F | VF |
| CLC88_RS18375 () | 3600959..3602452 | - | 1494 | WP_000249348.1 | Type II secretion system protein E | VF |
| CLC88_RS18380 () | 3602452..3604512 | - | 2061 | WP_000498824.1 | Type II secretion system protein D | VF |
| CLC88_RS18385 () | 3604542..3605501 | - | 960 | WP_000135073.1 | Type II secretion system protein C | VF |
| CLC88_RS18390 () | 3605519..3605929 | - | 411 | WP_001298744.1 | type II secretion system pilot lipoprotein GspS-beta | - |
| CLC88_RS18395 () | 3605995..3606804 | - | 810 | WP_001365924.1 | Leader peptidase PppA | VF |
| CLC88_RS18400 () | 3606944..3611512 | - | 4569 | WP_001748751.1 | hypothetical protein | VF |
| CLC88_RS18405 () | 3611998..3613680 | - | 1683 | WP_000259303.1 | glycolate permease GlcA | - |
| CLC88_RS18410 () | 3614036..3616207 | - | 2172 | WP_000084065.1 | malate synthase G | - |
| CLC88_RS18415 () | 3616229..3616633 | - | 405 | WP_000853256.1 | protein GlcG | - |
| CLC88_RS18420 () | 3616638..3617861 | - | 1224 | WP_001194666.1 | glycolate oxidase subunit GlcF | - |
| CLC88_RS18425 () | 3617872..3618924 | - | 1053 | WP_000943057.1 | glycolate oxidase subunit GlcE | - |
| CLC88_RS18430 () | 3618924..3620423 | - | 1500 | WP_000026148.1 | glycolate oxidase subunit GlcD | - |
| CLC88_RS18435 () | 3620674..3621438 | + | 765 | WP_001297764.1 | transcriptional regulator GlcC | - |
| CLC88_RS18440 () | 3621445..3622587 | - | 1143 | WP_000388786.1 | DNA-binding protein | - |
| CLC88_RS18445 () | 3622949..3624679 | + | 1731 | WP_000262939.1 | 4-hydroxyphenylalkanoate adenylyltransferase | VF |
| CLC88_RS18450 () | 3624676..3625590 | + | 915 | WP_001077143.1 | NAD-dependent epimerase/dehydratase family protein | - |
| CLC88_RS18455 () | 3625622..3625870 | + | 249 | WP_000248097.1 | acyl carrier protein | - |
| CLC88_RS18460 () | 3625870..3627042 | + | 1173 | WP_000524972.1 | 8-amino-7-oxononanoate synthase | VF |
| CLC88_RS18465 () | 3627078..3628157 | - | 1080 | WP_001300858.1 | LPS export ABC transporter permease LptG | - |
| CLC88_RS18470 () | 3628154..3629224 | - | 1071 | WP_000779661.1 | LPS export ABC transporter permease LptF | - |
| CLC88_RS18475 () | 3629255..3629815 | - | 561 | WP_001299422.1 | YtfJ family protein | - |
| CLC88_RS18480 () | 3629827..3630651 | - | 825 | WP_000984976.1 | hypothetical protein | - |
| CLC88_RS18485 () | 3630651..3632000 | - | 1350 | WP_000896880.1 | lipopolysaccharide biosynthesis protein | - |
| CLC88_RS18490 () | 3632046..3632804 | - | 759 | WP_000339512.1 | hypothetical protein | - |
| CLC88_RS18495 () | 3632836..3633549 | - | 714 | WP_001076233.1 | thymidylate kinase | - |
| CLC88_RS18500 () | 3633723..3634415 | + | 693 | WP_001190783.1 | thymidylate kinase | - |
| CLC88_RS18505 () | 3634464..3635963 | - | 1500 | WP_000933296.1 | inorganic phosphate transporter PitB | - |
| CLC88_RS18510 () | 3636255..3638114 | - | 1860 | WP_001345957.1 | bifunctional glutathionylspermidine amidase/synthase | - |
| CLC88_RS18515 () | 3638319..3639185 | + | 867 | WP_001345958.1 | glutathione-dependent disulfide-bond oxidoreductase | - |
| CLC88_RS18520 () | 3639485..3640465 | + | 981 | WP_000399648.1 | IS110 family transposase IS621 | Transposase |
| CLC88_RS18525 () | 3640587..3640835 | - | 249 | WP_000334896.1 | hydrogenase maturation factor HybG | - |
| CLC88_RS18530 () | 3640848..3641189 | - | 342 | WP_000544952.1 | hydrogenase maturation nickel metallochaperone HypA | - |
| CLC88_RS18535 () | 3641182..3641670 | - | 489 | WP_000134014.1 | hydrogenase-2 assembly chaperone | - |
| CLC88_RS18540 () | 3641663..3642157 | - | 495 | WP_001221953.1 | HyaD/HybD family hydrogenase maturation endopeptidase | - |
| CLC88_RS18545 () | 3642157..3643860 | - | 1704 | WP_000083065.1 | hydrogenase 2 large subunit | - |
| CLC88_RS18550 () | 3643857..3645035 | - | 1179 | WP_000017680.1 | Ni/Fe-hydrogenase cytochrome b subunit | - |
| CLC88_RS18555 () | 3645025..3646011 | - | 987 | WP_001081870.1 | hydrogenase 2 operon protein HybA | - |
| CLC88_RS18560 () | 3646014..3647132 | - | 1119 | WP_000145410.1 | hydrogenase 2 small subunit | - |
| CLC88_RS18565 () | 3647321..3647608 | - | 288 | WP_001059136.1 | DUF2623 domain-containing protein | - |
| CLC88_RS18570 () | 3647727..3648614 | - | 888 | WP_001297303.1 | dienelactone hydrolase family protein | - |
| CLC88_RS18575 () | 3648771..3649811 | + | 1041 | WP_000262156.1 | L-glyceraldehyde 3-phosphate reductase | - |
| CLC88_RS18580 () | 3649851..3650345 | - | 495 | WP_000439331.1 | TIGR00645 family protein | - |
| CLC88_RS18585 () | 3650536..3651420 | + | 885 | WP_000018760.1 | putative oxidoreductase YghA | VF |
| CLC88_RS18590 () | 3651692..3652117 | - | 426 | WP_001240712.1 | TonB system transport protein ExbD | - |
| CLC88_RS18595 () | 3652124..3652858 | - | 735 | WP_000527844.1 | tol-pal system-associated acyl-CoA thioesterase | - |
| CLC88_RS18600 () | 3653110..3654297 | + | 1188 | WP_000763931.1 | cystathionine beta-lyase | - |
| CLC88_RS18605 () | 3654437..3655096 | + | 660 | WP_000268419.1 | DedA family protein | - |
| CLC88_RS18610 () | 3655136..3656035 | - | 900 | WP_050864200.1 | DNA-binding transcriptional regulator YqhC | - |
| CLC88_RS18615 () | 3656229..3657392 | + | 1164 | WP_001058807.1 | alcohol dehydrogenase | - |
| CLC88_RS18620 () | 3657497..3658324 | + | 828 | WP_000013149.1 | 2,5-didehydrogluconate reductase DkgA | - |
| CLC88_RS18625 () | 3658524..3659450 | + | 927 | WP_000691598.1 | YbjP/YqhG family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|