NZ_CP0218851532747..1736568

MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 203822 bp
Accession: NZ_CP021885        Location: 1532747..1736568         Organism: Enterococcus faecium strain WEFA23       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDW54_RS07745 () 1528000..1528917 - 918 WP_002286294.1 ribokinase -
CDW54_RS07750 () 1529026..1530039 - 1014 WP_002298484.1 substrate-binding domain-containing protein -
CDW54_RS07755 () 1530120..1530719 - 600 WP_010718029.1 cysteine hydrolase -
CDW54_RS07760 () 1530904..1531605 + 702 WP_002296067.1 ABC transporter ATP-binding protein -
CDW54_RS07765 () 1531615..1534326 + 2712 WP_002301347.1 ABC transporter permease -
CDW54_RS07770 () 1534847..1536475 + 1629 WP_002286285.1 alpha,alpha-phosphotrehalase -
CDW54_RS07780 () 1536535..1537716 - 1182 WP_002317496.1 AI-2E family transporter -
CDW54_RS07785 () 1537968..1539491 + 1524 WP_010718030.1 High-affinity zinc uptake system binding-protein ZnuA VF
CDW54_RS07790 () 1539560..1540288 - 729 WP_002286278.1 LytTR family DNA-binding domain-containing protein -
CDW54_RS07795 () 1540301..1541581 - 1281 WP_002298495.1 sensor histidine kinase -
CDW54_RS07800 () 1541722..1542324 - 603 WP_002296063.1 accessory gene regulator B family protein -
CDW54_RS07805 () 1542454..1543632 - 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CDW54_RS07810 () 1543915..1544121 + 207 WP_002286271.1 hypothetical protein -
CDW54_RS07815 () 1544433..1545152 + 720 WP_002321450.1 deoxynucleoside kinase -
CDW54_RS07825 () 1545233..1545916 - 684 WP_002286265.1 DUF1275 domain-containing protein -
CDW54_RS07830 () 1546148..1548334 + 2187 WP_002286261.1 ATP-dependent helicase -
CDW54_RS07835 () 1548683..1549093 + 411 WP_101735328.1 Spx/MgsR family RNA polymerase-binding regulatory protein -
CDW54_RS07840 () 1549107..1549463 + 357 WP_101735329.1 Spx/MgsR family RNA polymerase-binding regulatory protein -
CDW54_RS07865 () 1555218..1555688 - 471 WP_002301238.1 glutathione peroxidase -
CDW54_RS07870 () 1555847..1556305 - 459 WP_002289439.1 S-ribosylhomocysteine lyase VF
CDW54_RS07875 () 1556476..1557621 - 1146 WP_002301236.1 cystathionine gamma-synthase -
CDW54_RS07880 () 1557634..1558551 - 918 WP_002289436.1 cysteine synthase family protein -
CDW54_RS07895 () 1558979..1559542 + 564 WP_002289434.1 elongation factor P -
CDW54_RS12820 () 1559643..1559813 + 171 WP_002301233.1 hypothetical protein -
CDW54_RS07900 () 1560028..1561287 + 1260 WP_002286883.1 diaminopimelate decarboxylase -
CDW54_RS07905 () 1561274..1562074 + 801 WP_002294349.1 diaminopimelate epimerase -
CDW54_RS07910 () 1562077..1562958 + 882 WP_002301231.1 4-hydroxy-tetrahydrodipicolinate synthase -
CDW54_RS07915 () 1562955..1563671 + 717 WP_002286877.1 4-hydroxy-tetrahydrodipicolinate reductase -
CDW54_RS07920 () 1563677..1564372 + 696 WP_002301230.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase VF
CDW54_RS07925 () 1564388..1565389 + 1002 WP_010718326.1 aspartate-semialdehyde dehydrogenase -
CDW54_RS07930 () 1565386..1566747 + 1362 WP_010718325.1 aspartate kinase -
CDW54_RS07935 () 1566707..1567858 + 1152 WP_002301227.1 amidohydrolase -
CDW54_RS07940 () 1567833..1569002 + 1170 WP_101735330.1 pyridoxal phosphate-dependent aminotransferase -
CDW54_RS07945 () 1569178..1570557 + 1380 WP_002301224.1 FAD-dependent oxidoreductase -
CDW54_RS07950 () 1570961..1571758 + 798 Protein_1414 IS3 family transposase ISEfa10 Transposase
CDW54_RS07955 () 1571947..1572615 + 669 WP_002300355.1 DUF421 domain-containing protein -
CDW54_RS07960 () 1572823..1573197 - 375 WP_101735331.1 hypothetical protein -
CDW54_RS07965 () 1573169..1574551 - 1383 WP_002286860.1 Y-family DNA polymerase -
CDW54_RS07970 () 1574707..1575894 - 1188 WP_002286858.1 galactokinase -
CDW54_RS07975 () 1575901..1576932 - 1032 WP_002300353.1 galactose mutarotase -
CDW54_RS07980 () 1576948..1578402 - 1455 WP_002300351.1 glycoside-pentoside-hexuronide (GPH):cation symporter -
CDW54_RS07985 () 1578577..1579482 + 906 WP_002286852.1 AraC family transcriptional regulator -
CDW54_RS07990 () 1579573..1580250 + 678 WP_002300349.1 NAD(P)H-dependent oxidoreductase -
CDW54_RS12825 () 1580247..1580417 + 171 WP_002286849.1 hypothetical protein -
CDW54_RS07995 () 1580531..1581427 + 897 WP_002300348.1 LysM peptidoglycan-binding domain-containing protein -
CDW54_RS08000 () 1581482..1582852 - 1371 WP_043902870.1 amino acid permease -
CDW54_RS08005 () 1583090..1583836 + 747 WP_002293686.1 High-affinity zinc uptake system ATP-binding protein ZnuC VF
CDW54_RS08010 () 1583833..1584672 + 840 WP_002286845.1 Manganese transport system membrane protein MntB VF
CDW54_RS08015 () 1584673..1585623 + 951 WP_002300346.1 Manganese ABC transporter substrate-binding lipoprotein VF
CDW54_RS08020 () 1585763..1586515 + 753 WP_002300345.1 hypothetical protein -
CDW54_RS08025 () 1586534..1587685 + 1152 WP_002293684.1 tRNA epoxyqueuosine(34) reductase QueG -
CDW54_RS08030 () 1588069..1588677 + 609 WP_002286836.1 LysM domain-containing protein -
CDW54_RS08035 () 1588845..1590482 + 1638 WP_010718323.1 phosphoenolpyruvate carboxykinase (ATP) -
CDW54_RS08040 () 1590554..1591666 - 1113 WP_002286834.1 FAD-binding oxidoreductase -
CDW54_RS08045 () 1591741..1593114 - 1374 WP_002293681.1 MFS transporter -
CDW54_RS12830 () 1593335..1593529 + 195 WP_002300337.1 hypothetical protein -
CDW54_RS08050 () 1593544..1593951 + 408 WP_002323732.1 GyrI-like domain-containing protein -
CDW54_RS08055 () 1594049..1594504 + 456 WP_002286829.1 arginine repressor -
CDW54_RS08060 () 1594522..1596024 + 1503 WP_010718320.1 Phosphomannomutase/phosphoglucomutase VF
CDW54_RS08065 () 1596119..1596325 + 207 WP_002293677.1 hypothetical protein -
CDW54_RS08070 () 1596411..1596812 + 402 WP_010718319.1 organic hydroperoxide resistance protein -
CDW54_RS08075 () 1596970..1598298 + 1329 WP_010718318.1 FAD-dependent oxidoreductase -
CDW54_RS08080 () 1598320..1598946 + 627 WP_002286816.1 cysteine hydrolase -
CDW54_RS08085 () 1599129..1599710 + 582 WP_002331663.1 TetR/AcrR family transcriptional regulator -
CDW54_RS08090 () 1600075..1600650 + 576 WP_010718317.1 SOS response-associated peptidase family protein -
CDW54_RS08095 () 1600855..1601193 - 339 WP_002286804.1 hypothetical protein -
CDW54_RS08105 () 1601481..1601711 + 231 WP_002323011.1 hypothetical protein Antitoxin Detail
CDW54_RS08110 () 1601711..1602052 + 342 WP_002302307.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
CDW54_RS08115 () 1602902..1603087 + 186 WP_002304207.1 hypothetical protein -
CDW54_RS12745 () 1604723..1604848 + 126 WP_002352139.1 LPXTG cell wall anchor domain-containing protein -
CDW54_RS08135 () 1604922..1605815 + 894 WP_002326335.1 hypothetical protein VF
CDW54_RS08140 () 1605999..1606673 + 675 WP_002291233.1 Response regulator protein GraR VF
CDW54_RS08145 () 1606691..1607716 + 1026 WP_010718316.1 sensor histidine kinase -
CDW54_RS08150 () 1607805..1608671 + 867 WP_002286769.1 glucose transporter GlcU -
CDW54_RS08155 () 1608708..1610084 + 1377 WP_002286768.1 amino acid permease -
CDW54_RS08160 () 1610185..1611381 - 1197 WP_002286766.1 toxic anion resistance protein -
CDW54_RS08165 () 1611505..1612167 - 663 WP_010718315.1 5-bromo-4-chloroindolyl phosphate hydrolysis family protein -
CDW54_RS08170 () 1612395..1612958 + 564 WP_002325125.1 NUDIX hydrolase -
CDW54_RS08175 () 1612971..1613255 + 285 WP_002286760.1 cell wall synthase accessory phosphoprotein MacP -
CDW54_RS08180 () 1613274..1613966 + 693 WP_002291218.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
CDW54_RS08185 () 1613978..1614523 + 546 WP_002291217.1 Isochorismatase family protein YecD VF
CDW54_RS08190 () 1614796..1618062 + 3267 WP_101735332.1 right-handed parallel beta-helix repeat-containing protein -
CDW54_RS08200 () 1618845..1620752 - 1908 WP_002318905.1 peptidase M13 -
CDW54_RS08205 () 1620882..1621757 + 876 WP_010718313.1 hypothetical protein -
CDW54_RS08210 () 1621837..1622811 + 975 WP_002286741.1 ribose-phosphate diphosphokinase -
CDW54_RS08215 () 1622991..1624136 + 1146 WP_002295158.1 cysteine desulfurase -
CDW54_RS08220 () 1624273..1624617 + 345 WP_002286736.1 DUF1831 domain-containing protein -
CDW54_RS08225 () 1624888..1626174 + 1287 WP_010718312.1 multidrug efflux MFS transporter EfmA -
CDW54_RS08230 () 1626312..1626911 - 600 WP_002291205.1 metallophosphoesterase -
CDW54_RS08235 () 1627315..1628436 + 1122 WP_010718311.1 tRNA 2-thiouridine(34) synthase MnmA -
CDW54_RS08240 () 1628682..1630103 + 1422 WP_010718310.1 arginine-ornithine antiporter -
CDW54_RS08245 () 1630117..1631235 + 1119 WP_010718309.1 aminotransferase -
CDW54_RS08250 () 1631295..1632587 - 1293 WP_002325116.1 multidrug efflux MFS transporter -
CDW54_RS08255 () 1632719..1633297 + 579 WP_077150393.1 TetR/AcrR family transcriptional regulator -
CDW54_RS08260 () 1633426..1633803 + 378 WP_002291196.1 DUF1033 family protein -
CDW54_RS08265 () 1633736..1635808 + 2073 WP_033583050.1 DNA topoisomerase III -
CDW54_RS08270 () 1636019..1636966 - 948 WP_002289773.1 Prophage bactoprenol glucosyl transferase VF
CDW54_RS08275 () 1637212..1637676 + 465 WP_002291193.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
CDW54_RS08280 () 1637738..1638781 - 1044 WP_002291191.1 putative sulfate exporter family transporter -
CDW54_RS08290 () 1639158..1640123 - 966 WP_010718307.1 TDT family transporter -
CDW54_RS08295 () 1640357..1641202 + 846 WP_002291186.1 HTH-type transcriptional regulator CysL VF
CDW54_RS08305 () 1641393..1642580 + 1188 WP_002291183.1 FtsW/RodA/SpoVE family cell cycle protein -
CDW54_RS08310 () 1642586..1642942 + 357 WP_002295166.1 arsenate reductase family protein -
CDW54_RS08315 () 1642944..1643282 + 339 WP_002291179.1 glycine cleavage system protein H -
CDW54_RS08320 () 1643677..1644711 + 1035 WP_002304234.1 Methionine import ATP-binding protein MetN 2 VF
CDW54_RS08325 () 1644704..1645390 + 687 WP_002287674.1 ABC transporter permease -
CDW54_RS08330 () 1645414..1646262 + 849 WP_002287678.1 Methionine-binding lipoprotein MetQ VF
CDW54_RS08335 () 1646459..1647232 + 774 WP_002287679.1 Fe-S cluster assembly ATPase SufC -
CDW54_RS08340 () 1647245..1648531 + 1287 WP_101735333.1 Fe-S cluster assembly protein SufD -
CDW54_RS08345 () 1648528..1649763 + 1236 WP_010718306.1 cysteine desulfurase -
CDW54_RS08350 () 1649750..1650220 + 471 WP_002287684.1 SUF system NifU family Fe-S cluster assembly protein -
CDW54_RS08355 () 1650225..1651616 + 1392 WP_002287686.1 Fe-S cluster assembly protein SufB -
CDW54_RS08360 () 1651713..1652864 - 1152 WP_002336282.1 Transposase from transposon Tn916 ; Integrase Integrase
CDW54_RS08365 () 1652908..1653525 - 618 WP_025479542.1 helix-turn-helix transcriptional regulator -
CDW54_RS08370 () 1653732..1653956 + 225 WP_002336284.1 helix-turn-helix domain-containing protein -
CDW54_RS08375 () 1653953..1654225 + 273 WP_073463006.1 DNA-binding protein -
CDW54_RS08380 () 1654301..1654546 + 246 WP_073984966.1 hypothetical protein -
CDW54_RS08385 () 1654684..1654899 + 216 WP_101735334.1 hypothetical protein -
CDW54_RS08390 () 1654896..1655801 + 906 WP_101735335.1 primase alpha helix C-terminal domain-containing protein -
CDW54_RS08395 () 1655798..1657189 + 1392 WP_101735336.1 DNA primase family protein -
CDW54_RS08400 () 1657491..1657898 + 408 WP_101735337.1 DUF3206 domain-containing protein -
CDW54_RS08405 () 1657901..1658098 + 198 WP_101735338.1 hypothetical protein -
CDW54_RS08410 () 1658120..1658500 + 381 WP_101735339.1 HNH endonuclease -
CDW54_RS08415 () 1658635..1658790 + 156 WP_005879181.1 DUF2292 domain-containing protein -
CDW54_RS08420 () 1658859..1659332 + 474 WP_073462992.1 phage terminase small subunit P27 family -
CDW54_RS08425 () 1659329..1661023 + 1695 WP_101735340.1 terminase large subunit -
CDW54_RS08430 () 1660989..1661174 + 186 WP_002306148.1 hypothetical protein -
CDW54_RS08435 () 1661178..1662353 + 1176 WP_101735341.1 phage portal protein -
CDW54_RS08440 () 1662346..1663869 + 1524 WP_101735342.1 phage major capsid protein -
CDW54_RS08445 () 1663923..1664207 + 285 WP_101735343.1 head-tail connector protein -
CDW54_RS08450 () 1664194..1664529 + 336 WP_101735344.1 phage head closure protein -
CDW54_RS08455 () 1664531..1664725 + 195 WP_101735345.1 head-tail connector protein -
CDW54_RS08460 () 1664839..1665531 + 693 WP_101735346.1 hypothetical protein -
CDW54_RS08465 () 1665550..1666203 + 654 WP_101735347.1 hypothetical protein -
CDW54_RS08470 () 1666463..1667602 - 1140 WP_002327677.1 Transposase from transposon Tn916 ; Integrase Integrase
CDW54_RS08475 () 1667653..1668006 - 354 Protein_1516 transcriptional regulator -
CDW54_RS08500 () 1669945..1670259 + 315 WP_002327679.1 hypothetical protein -
CDW54_RS08505 () 1670312..1671070 - 759 WP_033603054.1 hypothetical protein -
CDW54_RS08510 () 1671191..1671436 + 246 WP_002313380.1 helix-turn-helix domain-containing protein -
CDW54_RS08515 () 1671512..1671790 + 279 WP_002314576.1 hypothetical protein -
CDW54_RS08520 () 1672210..1673372 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
CDW54_RS08530 () 1673803..1674228 + 426 WP_002316489.1 hypothetical protein -
CDW54_RS08535 () 1674838..1676334 - 1497 WP_101735348.1 helix-turn-helix domain-containing protein -
CDW54_RS08540 () 1676689..1680141 + 3453 WP_010718304.1 hypothetical protein VF
CDW54_RS08545 () 1680144..1681565 + 1422 WP_002327400.1 hypothetical protein VF
CDW54_RS08550 () 1681562..1683439 + 1878 WP_101735349.1 hypothetical protein VF
CDW54_RS08555 () 1683531..1684361 + 831 WP_010718303.1 hypothetical protein VF
CDW54_RS08570 () 1686265..1687440 + 1176 Protein_1530 PTS lactose transporter subunit IIBC -
CDW54_RS08575 () 1687582..1688988 + 1407 WP_010718300.1 6-phospho-beta-galactosidase -
CDW54_RS12835 () 1689111..1689284 + 174 WP_164884865.1 DUF3884 family protein -
CDW54_RS08585 () 1689305..1690204 + 900 WP_010718299.1 aldose 1-epimerase family protein -
CDW54_RS08590 () 1690536..1690826 - 291 WP_010718298.1 hypothetical protein -
CDW54_RS08595 () 1690907..1691410 - 504 Protein_1535 peptidase -
CDW54_RS08600 () 1691373..1691609 + 237 WP_071243184.1 helix-turn-helix domain-containing protein -
CDW54_RS08605 () 1691846..1693960 + 2115 WP_010718296.1 putative ATP-dependent Clp protease ATP-binding subunit VF
CDW54_RS08610 () 1694141..1694455 - 315 Protein_1538 transposase -
CDW54_RS08615 () 1694528..1694764 + 237 WP_025480325.1 hypothetical protein -
CDW54_RS08620 () 1694983..1695174 + 192 WP_002314345.1 hypothetical protein -
CDW54_RS08625 () 1695692..1697041 + 1350 WP_101735351.1 primase C-terminal domain-containing protein -
CDW54_RS08630 () 1697085..1697279 + 195 WP_002311030.1 hypothetical protein -
CDW54_RS12840 () 1697293..1697433 + 141 WP_002316998.1 hypothetical protein -
CDW54_RS08635 () 1697411..1699252 + 1842 WP_077150478.1 type IA DNA topoisomerase -
CDW54_RS08640 () 1699809..1699997 + 189 WP_038809792.1 hypothetical protein -
CDW54_RS08650 () 1700722..1701144 + 423 WP_002307506.1 cupin domain-containing protein -
CDW54_RS08655 () 1701228..1701881 + 654 WP_025370695.1 putative iron export ATP-binding protein FetA VF
CDW54_RS08660 () 1701878..1702642 + 765 WP_002311027.1 iron export ABC transporter permease subunit FetB -
CDW54_RS08670 () 1703152..1704314 + 1163 WP_094932120.1 IS3 family transposase IS1485 Transposase
CDW54_RS08680 () 1704540..1705433 + 894 WP_158296032.1 IS3 family transposase IS1485 Transposase
CDW54_RS08690 () 1707429..1708094 - 666 WP_002326331.1 helix-turn-helix domain-containing protein -
CDW54_RS08695 () 1708274..1710256 + 1983 WP_064485101.1 DUF1430 domain-containing protein -
CDW54_RS08700 () 1710260..1710897 + 638 Protein_1553 putative ABC transporter ATP-binding protein YknY VF
CDW54_RS08705 () 1711271..1712182 + 912 WP_002316482.1 Foldase protein PrsA VF
CDW54_RS08710 () 1712398..1712835 + 438 WP_002328523.1 hypothetical protein -
CDW54_RS08715 () 1712930..1713814 + 885 WP_002328522.1 diacylglycerol kinase family lipid kinase -
CDW54_RS08725 () 1714035..1717205 + 3171 WP_063285981.1 hypothetical protein -
CDW54_RS08730 () 1717225..1718253 + 1029 WP_010718292.1 DUF916 and DUF3324 domain-containing protein -
CDW54_RS08735 () 1718250..1719009 + 760 Protein_1559 WxL domain-containing protein -
CDW54_RS08740 () 1719095..1719835 - 741 WP_002306055.1 LytTR family DNA-binding domain-containing protein -
CDW54_RS08745 () 1719896..1721149 + 1254 WP_010718291.1 GHKL domain-containing protein -
CDW54_RS08750 () 1721450..1721698 + 249 Protein_1562 winged helix-turn-helix transcriptional regulator -
CDW54_RS08755 () 1721820..1722146 + 327 WP_002291148.1 nucleotide pyrophosphohydrolase -
CDW54_RS08760 () 1722214..1722927 + 714 WP_002318718.1 class A sortase -
CDW54_RS08765 () 1723237..1724089 + 853 Protein_1565 PRD domain-containing protein -
CDW54_RS08770 () 1724210..1726075 + 1866 WP_010718289.1 beta-glucoside-specific PTS transporter subunit IIABC -
CDW54_RS08775 () 1726089..1727531 + 1443 WP_101735352.1 glycoside hydrolase family 1 protein -
CDW54_RS08780 () 1727639..1728340 + 702 WP_002346739.1 GntR family transcriptional regulator -
CDW54_RS08790 () 1728499..1728978 + 480 Protein_1569 PTS fructose transporter subunit IIC -
CDW54_RS08805 () 1729826..1730401 + 576 WP_002293608.1 TIGR00730 family Rossman fold protein -
CDW54_RS08810 () 1730401..1730841 + 441 WP_101735353.1 nucleoside 2-deoxyribosyltransferase -
CDW54_RS08815 () 1730857..1731558 + 702 WP_002340345.1 deoxynucleoside kinase -
CDW54_RS08820 () 1732045..1732470 - 426 WP_002299985.1 hypothetical protein -
CDW54_RS08825 () 1732844..1733815 + 972 WP_101735354.1 LacI family transcriptional regulator -
CDW54_RS08830 () 1733847..1735244 + 1398 WP_101735355.1 glycoside hydrolase family 1 protein -
CDW54_RS08835 () 1735403..1736026 + 624 WP_002293828.1 hypothetical protein -
CDW54_RS08840 () 1736502..1738595 + 2094 WP_010718287.1 LTA synthase family protein -
CDW54_RS08845 () 1738755..1739621 + 867 WP_002325855.1 Rgg/GadR/MutR family transcriptional regulator -
CDW54_RS08850 () 1739643..1740080 - 438 WP_002293327.1 nucleoside-diphosphate kinase -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance