MGE detailed information
MGE type: Mobilizable plasmid MGE length: 58211 bp
Accession: NZ_CP019995 Location: 1..58211 Organism: Enterococcus faecium isolate 2014-VREF-268 Replicon: plasmid p268-3
Accession: NZ_CP019995 Location: 1..58211 Organism: Enterococcus faecium isolate 2014-VREF-268 Replicon: plasmid p268-3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B4W81_RS17235 () | 1..696 | - | 696 | Protein_0 | D-alanine--(R)-lactate ligase VanA | - |
| B4W81_RS17240 () | 709..1676 | - | 968 | Protein_1 | VanH-A/VanH-Pt family D-lactate dehydrogenase | - |
| B4W81_RS17245 () | 1890..2979 | - | 1090 | Protein_2 | sensor histidine kinase | - |
| B4W81_RS17250 () | 3016..3709 | - | 694 | Protein_3 | Transcriptional regulatory protein WalR | VF |
| B4W81_RS17255 () | 3861..5033 | + | 1173 | WP_002323245.1 | IS256 family transposase IS1542 | Transposase |
| B4W81_RS17260 () | 5255..5626 | - | 372 | Protein_5 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| B4W81_RS17265 () | 5683..6352 | - | 670 | Protein_6 | IS6 family transposase IS1216V | Transposase |
| B4W81_RS17270 () | 6428..6754 | - | 327 | Protein_7 | hypothetical protein | - |
| B4W81_RS17275 () | 6867..7133 | - | 267 | WP_010729835.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| B4W81_RS17280 () | 7135..7356 | - | 222 | WP_010729836.1 | DUF1778 domain-containing protein | - |
| B4W81_RS17285 () | 7582..8400 | + | 819 | WP_002360989.1 | AAA family ATPase | - |
| B4W81_RS17290 () | 8404..8700 | + | 297 | WP_002320793.1 | hypothetical protein | - |
| B4W81_RS17295 () | 8882..9235 | - | 354 | WP_010729838.1 | hypothetical protein | - |
| B4W81_RS17300 () | 9255..10310 | - | 1056 | WP_010730992.1 | ParM/StbA family protein | - |
| B4W81_RS17305 () | 10526..10924 | + | 399 | WP_010730993.1 | hypothetical protein | - |
| B4W81_RS17970 () | 10927..11100 | + | 174 | WP_002320797.1 | hypothetical protein | - |
| B4W81_RS17975 () | 13073..13246 | - | 174 | WP_002320797.1 | hypothetical protein | - |
| B4W81_RS17310 () | 13249..13647 | - | 399 | WP_010730993.1 | hypothetical protein | - |
| B4W81_RS17315 () | 13863..14918 | + | 1056 | WP_010730992.1 | ParM/StbA family protein | - |
| B4W81_RS17320 () | 14938..15291 | + | 354 | WP_010729838.1 | hypothetical protein | - |
| B4W81_RS17325 () | 15473..15769 | - | 297 | WP_002320793.1 | hypothetical protein | - |
| B4W81_RS17330 () | 15773..16591 | - | 819 | WP_002360989.1 | AAA family ATPase | - |
| B4W81_RS17335 () | 16817..17038 | + | 222 | WP_010729836.1 | DUF1778 domain-containing protein | - |
| B4W81_RS17340 () | 17040..17306 | + | 267 | WP_010729835.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| B4W81_RS17345 () | 17419..17745 | + | 327 | Protein_24 | hypothetical protein | - |
| B4W81_RS17350 () | 17821..18490 | + | 670 | Protein_25 | IS6 family transposase IS1216V | Transposase |
| B4W81_RS17355 () | 18547..18918 | + | 372 | Protein_26 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| B4W81_RS17360 () | 19140..20312 | - | 1173 | WP_002323245.1 | IS256 family transposase IS1542 | Transposase |
| B4W81_RS17365 () | 20464..21159 | + | 696 | WP_001280781.1 | Transcriptional regulatory protein WalR | VF |
| B4W81_RS17370 () | 21137..22291 | + | 1155 | WP_002305818.1 | VanA-type vancomycin resistance histidine kinase VanS | - |
| B4W81_RS17375 () | 22506..23474 | + | 969 | WP_001059542.1 | D-specific alpha-keto acid dehydrogenase | ARG |
| B4W81_RS17380 () | 23467..24498 | + | 1032 | WP_001079845.1 | Vancomycin/teicoplanin A-type resistance protein VanA | ARG |
| B4W81_RS17385 () | 24504..25112 | + | 609 | WP_000402347.1 | D-alanyl-D-alanine dipeptidase | ARG |
| B4W81_RS17390 () | 25201..25881 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| B4W81_RS17395 () | 26176..27087 | + | 912 | WP_001812592.1 | D-Ala-D-Ala carboxypeptidase VanY-A | - |
| B4W81_RS17400 () | 27240..27725 | + | 486 | WP_000516404.1 | glycopeptide resistance protein VanZ-A | - |
| B4W81_RS17405 () | 28012..28341 | - | 330 | WP_154067203.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| B4W81_RS17410 () | 28403..29089 | + | 687 | WP_059355960.1 | IS6 family transposase IS1216E | Transposase |
| B4W81_RS17415 () | 29149..30444 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| B4W81_RS17420 () | 30689..30940 | + | 252 | Protein_39 | GNAT family N-acetyltransferase | - |
| B4W81_RS17425 () | 31033..31827 | + | 795 | WP_001096887.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| B4W81_RS17430 () | 32237..32320 | + | 84 | Protein_41 | peptide-binding protein | - |
| B4W81_RS17435 () | 32369..32452 | + | 84 | WP_031929417.1 | 23S rRNA methyltransferase attenuator leader peptide ErmL | - |
| B4W81_RS17440 () | 32577..33314 | + | 738 | WP_001038796.1 | rRNA adenine N-6-methyltransferase | ARG |
| B4W81_RS17445 () | 33577..34440 | - | 864 | WP_001284311.1 | toxin zeta | Toxin Detail |
| B4W81_RS17450 () | 34442..34714 | - | 273 | WP_000301765.1 | antitoxin | Antitoxin Detail |
| B4W81_RS17455 () | 34731..34940 | - | 210 | WP_000527318.1 | peptide-binding protein | - |
| B4W81_RS17460 () | 35038..35295 | - | 258 | WP_002347171.1 | hypothetical protein | - |
| B4W81_RS17465 () | 35351..36031 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| B4W81_RS17470 () | 35936..36803 | + | 868 | Protein_49 | Replication initiation protein | Relaxase |
| B4W81_RS17475 () | 36800..37033 | + | 234 | WP_002303408.1 | hypothetical protein | - |
| B4W81_RS17480 () | 37026..37445 | + | 420 | WP_044384217.1 | hypothetical protein | - |
| B4W81_RS17485 () | 37424..37762 | + | 339 | WP_171970646.1 | hypothetical protein | - |
| B4W81_RS17490 () | 37766..38128 | + | 363 | WP_002298418.1 | hypothetical protein | - |
| B4W81_RS17980 () | 38248..38438 | + | 191 | Protein_54 | hypothetical protein | - |
| B4W81_RS17985 () | 39215..39757 | + | 543 | WP_162536231.1 | hypothetical protein | - |
| B4W81_RS17500 () | 40206..40490 | + | 285 | Protein_56 | replication protein | - |
| B4W81_RS17505 () | 40545..41225 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| B4W81_RS17510 () | 41300..41638 | - | 339 | Protein_58 | replication protein | - |
| B4W81_RS17515 () | 41705..41860 | - | 156 | WP_002299939.1 | ribbon-helix-helix domain-containing protein | - |
| B4W81_RS17520 () | 42477..42698 | + | 222 | WP_002299940.1 | hypothetical protein | - |
| B4W81_RS17525 () | 42699..42956 | + | 258 | WP_002299941.1 | hypothetical protein | - |
| B4W81_RS17530 () | 43092..43376 | - | 285 | WP_079200807.1 | hypothetical protein | - |
| B4W81_RS17535 () | 43418..44098 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| B4W81_RS17540 () | 44136..44450 | - | 315 | WP_002347145.1 | hypothetical protein | - |
| B4W81_RS17545 () | 44585..46078 | - | 1494 | WP_000947691.1 | primase C-terminal domain-containing protein | - |
| B4W81_RS17550 () | 46690..47643 | + | 954 | WP_000429439.1 | ParA family protein | - |
| B4W81_RS17555 () | 47615..47890 | + | 276 | WP_001196543.1 | hypothetical protein | - |
| B4W81_RS17560 () | 48083..48337 | + | 255 | WP_000199136.1 | IS3 family transposase ISBce13 | Transposase |
| B4W81_RS17565 () | 48448..48702 | + | 255 | WP_002322130.1 | IS3 family transposase | - |
| B4W81_RS17570 () | 48863..49543 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| B4W81_RS17575 () | 49599..50117 | + | 519 | Protein_71 | IS3 family transposase IS1485 | Transposase |
| B4W81_RS17580 () | 50218..50790 | + | 573 | WP_073120187.1 | IS3 family transposase ISBce13 | Transposase |
| B4W81_RS17585 () | 51146..51718 | - | 573 | WP_002303206.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| B4W81_RS17590 () | 51734..52339 | - | 606 | WP_000599739.1 | cell filamentation protein | - |
| B4W81_RS17595 () | 52537..53217 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| B4W81_RS17600 () | 53313..53936 | - | 624 | WP_002288897.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| B4W81_RS17605 () | 54207..54719 | - | 513 | WP_000774078.1 | hypothetical protein | - |
| B4W81_RS17610 () | 54726..55244 | - | 519 | WP_000357244.1 | YfbU family protein | - |
| B4W81_RS17615 () | 55406..55618 | - | 213 | WP_002349227.1 | hypothetical protein | - |
| B4W81_RS17620 () | 55828..55993 | + | 166 | Protein_80 | IS6 family transposase IS1216V | Transposase |
| B4W81_RS17625 () | 56058..57361 | - | 1304 | Protein_81 | ISL3 family transposase | - |
| B4W81_RS17630 () | 57820..58104 | + | 285 | WP_002347536.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|