NZ_CP0199532391051..2592008

MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 200958 bp
Accession: NZ_CP019953        Location: 2391051..2592008         Organism: Escherichia coli M8       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B2H83_RS11990 () 2386985..2387539 + 555 WP_000030727.1 propanediol utilization microcompartment protein PduT -
B2H83_RS11995 () 2387539..2387889 + 351 WP_000211394.1 propanediol utilization microcompartment protein PduU -
B2H83_RS12000 () 2387894..2388337 + 444 WP_001369832.1 EutP/PduV family microcompartment system protein -
B2H83_RS12005 () 2388438..2388767 - 330 WP_000450409.1 DUF496 family protein -
B2H83_RS12010 () 2388939..2389457 - 519 Protein_2313 hypothetical protein -
B2H83_RS12015 () 2389552..2390532 - 981 WP_000399648.1 IS110-like element IS621 family transposase -
B2H83_RS12025 () 2390596..2391276 - 681 WP_001200880.1 FUSC family protein -
B2H83_RS12030 () 2391474..2391947 - 474 WP_001105415.1 DNA gyrase inhibitor SbmC -
B2H83_RS12035 () 2392066..2393232 - 1167 WP_001296209.1 serine-type D-Ala-D-Ala carboxypeptidase DacD -
B2H83_RS12040 () 2393441..2394868 + 1428 WP_000980597.1 exodeoxyribonuclease I -
B2H83_RS12045 () 2394911..2395138 - 228 WP_000985273.1 sulfurtransferase TusA family protein -
B2H83_RS12050 () 2395152..2396210 - 1059 WP_000492346.1 transport protein YeeE -
B2H83_RS12055 () 2396389..2397747 - 1359 WP_000019197.1 putrescine/proton symporter PlaP -
B2H83_RS12060 () 2397737..2397799 - 63 WP_010723108.1 membrane protein YoeI -
B2H83_RS12065 () 2398014..2398943 - 930 WP_000803351.1 LysR family transcriptional regulator -
B2H83_RS12070 () 2398989..2399813 - 825 WP_000754749.1 SDR family oxidoreductase -
B2H83_RS12075 () 2399896..2400150 - 255 WP_000767829.1 type II toxin-antitoxin system mRNA interferase toxin YoeB Toxin Detail
B2H83_RS12080 () 2400147..2400398 - 252 WP_001259255.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin Detail
B2H83_RS12085 () 2400681..2400731 + 51 WP_001364200.1 his operon leader peptide -
B2H83_RS12090 () 2400877..2401776 + 900 WP_000131782.1 ATP phosphoribosyltransferase -
B2H83_RS12095 () 2401782..2403086 + 1305 WP_001369878.1 histidinol dehydrogenase -
B2H83_RS12100 () 2403083..2404153 + 1071 WP_000108962.1 histidinol-phosphate transaminase -
B2H83_RS12105 () 2404153..2405220 + 1068 WP_000080093.1 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB -
B2H83_RS12110 () 2405220..2405810 + 591 WP_001103560.1 imidazole glycerol phosphate synthase subunit HisH -
B2H83_RS12115 () 2405810..2406547 + 738 WP_000586485.1 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase -
B2H83_RS12120 () 2406529..2407305 + 777 WP_000880189.1 imidazole glycerol phosphate synthase subunit HisF -
B2H83_RS12125 () 2407299..2407910 + 612 WP_000954872.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE -
B2H83_RS12130 () 2408006..2408983 - 978 WP_001369885.1 LPS O-antigen chain length determinant protein WzzB -
B2H83_RS12135 () 2409254..2410416 + 1163 WP_085947771.1 IS3-like element IS3 family transposase -
B2H83_RS12140 () 2410670..2411674 + 1005 WP_000670926.1 NAD-dependent epimerase -
B2H83_RS12145 () 2411740..2412906 - 1167 WP_000704791.1 UDP-glucose 6-dehydrogenase -
B2H83_RS12150 () 2413155..2414561 - 1407 WP_000043488.1 NADP-dependent phosphogluconate dehydrogenase -
B2H83_RS12155 () 2414621..2415634 - 1014 WP_000866330.1 UDP-glucose 4-epimerase GalE -
B2H83_RS12160 () 2415669..2416847 - 1179 WP_024245840.1 glycosyltransferase family 4 protein -
B2H83_RS12165 () 2416847..2417980 - 1134 WP_000114037.1 glycosyltransferase family 4 protein -
B2H83_RS12170 () 2417977..2418516 - 540 WP_000586627.1 acyltransferase -
B2H83_RS12175 () 2418513..2419565 - 1053 WP_001227586.1 glycosyltransferase family 1 protein -
B2H83_RS12180 () 2419568..2420755 - 1188 WP_001369880.1 O113 family O-antigen polymerase -
B2H83_RS12185 () 2420771..2421691 - 921 WP_001058562.1 glycosyltransferase -
B2H83_RS12190 () 2421693..2423114 - 1422 WP_032227910.1 O113 family O-antigen flippase -
B2H83_RS12195 () 2423434..2424327 - 894 WP_000183060.1 UTP--glucose-1-phosphate uridylyltransferase GalF -
B2H83_RS12200 () 2424502..2425896 - 1395 WP_001116018.1 colanic acid biosynthesis protein WcaM -
B2H83_RS12205 () 2425907..2427127 - 1221 WP_000862664.1 colanic acid biosynthesis glycosyltransferase WcaL -
B2H83_RS12210 () 2427124..2428404 - 1281 WP_000770835.1 colanic acid biosynthesis pyruvyl transferase WcaK -
B2H83_RS12215 () 2428776..2430254 - 1479 WP_000058499.1 colanic acid undecaprenyl disphosphate flippase WzxC -
B2H83_RS12220 () 2430256..2431650 - 1395 WP_000183144.1 undecaprenyl-phosphate glucose phosphotransferase -
B2H83_RS12225 () 2431705..2433075 - 1371 WP_001313977.1 colanic acid biosynthesis phosphomannomutase CpsG -
B2H83_RS12230 () 2433177..2434613 - 1437 WP_000079285.1 mannose-1-phosphate guanyltransferase -
B2H83_RS12235 () 2434616..2435839 - 1224 WP_000699721.1 colanic acid biosynthesis fucosyltransferase WcaI -
B2H83_RS12240 () 2435836..2436315 - 480 WP_000479836.1 GDP-mannose mannosyl hydrolase -
B2H83_RS12245 () 2436318..2437283 - 966 WP_000043598.1 GDP-L-fucose synthase -
B2H83_RS12250 () 2437286..2438407 - 1122 WP_000048190.1 GDP-mannose 4,6-dehydratase -
B2H83_RS12255 () 2438433..2438981 - 549 WP_001153581.1 colanic acid biosynthesis acetyltransferase WcaF -
B2H83_RS12260 () 2438997..2439743 - 747 WP_129541940.1 colanic acid biosynthesis glycosyltransferase WcaE -
B2H83_RS12265 () 2439754..2440971 - 1218 WP_000107788.1 putative colanic acid polymerase WcaD -
B2H83_RS12270 () 2440946..2442163 - 1218 WP_001023900.1 colanic acid biosynthesis glycosyltransferase WcaC -
B2H83_RS12275 () 2442160..2442648 - 489 WP_000888740.1 colanic acid biosynthesis acetyltransferase WcaB -
B2H83_RS12280 () 2442651..2443490 - 840 WP_000654516.1 colanic acid biosynthesis glycosyltransferase WcaA -
B2H83_RS12285 () 2443668..2445830 - 2163 WP_000137136.1 tyrosine-protein kinase Wzc -
B2H83_RS12290 () 2445833..2446276 - 444 WP_000482901.1 low molecular weight protein-tyrosine-phosphatase Wzb -
B2H83_RS12295 () 2446282..2447421 - 1140 WP_000978094.1 polysaccharide export protein Wza -
B2H83_RS26460 () 2447730..2447879 + 150 WP_162829205.1 hypothetical protein -
B2H83_RS12300 () 2448080..2449663 + 1584 WP_001300971.1 TerC family protein -
B2H83_RS12305 () 2449937..2451790 - 1854 WP_001252331.1 outer membrane assembly protein AsmA -
B2H83_RS12310 () 2451812..2452393 - 582 WP_001234767.1 dCTP deaminase -
B2H83_RS12315 () 2452485..2453126 - 642 WP_001295424.1 uridine kinase -
B2H83_RS12320 () 2453444..2456761 + 3318 WP_129541941.1 diguanylate cyclase -
B2H83_RS12325 () 2456800..2457657 - 858 WP_000288410.1 DNA-3-methyladenine glycosylase 2 -
B2H83_RS12330 () 2457791..2459143 + 1353 WP_000469734.1 molecular chaperone -
B2H83_RS12335 () 2459155..2461095 - 1941 WP_001347704.1 protein kinase YegI -
B2H83_RS12340 () 2461092..2461853 - 762 WP_000119072.1 protein phosphatase 2C domain-containing protein -
B2H83_RS12345 () 2461850..2462509 - 660 WP_000003178.1 VWA domain-containing protein -
- () 2462690..2462832 + 143 NuclAT_1 - -
- () 2462690..2462832 + 143 NuclAT_1 - -
- () 2462690..2462832 + 143 NuclAT_1 - -
- () 2462690..2462832 + 143 NuclAT_1 - -
B2H83_RS12350 () 2462730..2462789 - 60 WP_010723109.1 type I toxin-antitoxin system toxin IbsA -
- () 2463025..2463160 + 136 NuclAT_3 - -
- () 2463025..2463160 + 136 NuclAT_3 - -
- () 2463025..2463160 + 136 NuclAT_3 - -
- () 2463025..2463160 + 136 NuclAT_3 - -
B2H83_RS12355 () 2463062..2463118 - 57 WP_001386899.1 type I toxin-antitoxin system Ibs family toxin -
B2H83_RS12360 () 2463292..2464863 - 1572 WP_000381416.1 IS66 family transposase -
B2H83_RS12365 () 2464883..2465230 - 348 WP_000624618.1 IS66 family insertion sequence element accessory protein TnpB -
B2H83_RS12370 () 2465230..2465880 - 651 WP_000993931.1 IS66 family insertion sequence hypothetical protein -
- () 2466065..2466200 + 136 NuclAT_4 - -
- () 2466065..2466200 + 136 NuclAT_4 - -
- () 2466065..2466200 + 136 NuclAT_4 - -
- () 2466065..2466200 + 136 NuclAT_4 - -
B2H83_RS12375 () 2466102..2466158 - 57 WP_001386901.1 type I toxin-antitoxin system Ibs family toxin -
B2H83_RS12380 () 2466437..2467684 + 1248 WP_000678949.1 multidrug efflux RND transporter subunit MdtA -
B2H83_RS12385 () 2467684..2470806 + 3123 WP_001197867.1 multidrug efflux RND transporter permease subunit MdtB -
B2H83_RS12390 () 2470807..2473884 + 3078 WP_000667531.1 multidrug efflux RND transporter permease subunit MdtC -
B2H83_RS12395 () 2473885..2475300 + 1416 WP_000130850.1 MFS transporter -
B2H83_RS12400 () 2475297..2476700 + 1404 WP_000675150.1 two-component system sensor histidine kinase BaeS -
B2H83_RS12405 () 2476697..2477419 + 723 WP_000137869.1 two-component system response regulator BaeR -
B2H83_RS12410 () 2477610..2477942 + 333 WP_000929408.1 YegP family protein -
B2H83_RS12415 () 2478151..2478447 + 297 WP_001307279.1 type II toxin-antitoxin system ParD family antitoxin -
B2H83_RS12420 () 2478449..2478745 + 297 WP_001220181.1 type II toxin-antitoxin system RelE/ParE family toxin -
B2H83_RS12425 () 2478848..2480209 + 1362 WP_086255113.1 tRNA 5-hydroxyuridine modification protein YegQ -
B2H83_RS12430 () 2480539..2480856 - 318 WP_000716757.1 hypothetical protein -
B2H83_RS12435 () 2481271..2482170 + 900 WP_000807362.1 lipid kinase YegS -
B2H83_RS12440 () 2482252..2483031 - 780 WP_000178552.1 DeoR/GlpR family DNA-binding transcription regulator -
B2H83_RS12445 () 2483131..2484171 - 1041 WP_000844200.1 galactitol-1-phosphate 5-dehydrogenase -
B2H83_RS12450 () 2484219..2485574 - 1356 WP_000490714.1 galactitol-specific PTS transporter subunit IIC -
B2H83_RS12455 () 2485578..2485862 - 285 WP_000823272.1 PTS galactitol transporter subunit IIB -
B2H83_RS12460 () 2485893..2486345 - 453 WP_000182899.1 PTS galactitol transporter subunit IIA -
B2H83_RS12465 () 2486355..2487617 - 1263 WP_129541942.1 tagatose-bisphosphate aldolase subunit GatZ -
B2H83_RS12470 () 2487646..2488500 - 855 WP_000289788.1 tagatose-bisphosphate aldolase subunit GatY -
B2H83_RS12480 () 2488810..2489862 - 1053 WP_000129551.1 class I fructose-bisphosphate aldolase -
B2H83_RS12485 () 2490119..2491396 + 1278 WP_000858484.1 nucleoside permease -
B2H83_RS12490 () 2491393..2492397 + 1005 WP_000846219.1 ADP-ribosylglycohydrolase family protein -
B2H83_RS12495 () 2492394..2493359 + 966 WP_000011973.1 sugar kinase -
B2H83_RS12500 () 2493333..2494079 - 747 WP_000434038.1 GntR family transcriptional regulator -
B2H83_RS12505 () 2494131..2494949 - 819 WP_001315719.1 glycoside hydrolase family 25 protein -
B2H83_RS12510 () 2495014..2495814 - 801 WP_000822274.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
B2H83_RS12515 () 2495811..2496599 - 789 WP_001195590.1 hydroxyethylthiazole kinase -
B2H83_RS12520 () 2496822..2497094 - 273 WP_000019944.1 Ni(II)/Co(II)-binding transcriptional repressor RcnR -
B2H83_RS12525 () 2497215..2498039 + 825 WP_000134576.1 nickel/cobalt efflux protein RcnA -
B2H83_RS12530 () 2498258..2498596 + 339 WP_000153067.1 Ni(II)/Co(II) efflux transporter accessory subunit RcnB -
B2H83_RS12535 () 2498678..2499712 - 1035 WP_001026151.1 putative fimbrial-like adhesin protein -
B2H83_RS12540 () 2499726..2502206 - 2481 WP_000945406.1 fimbrial biogenesis outer membrane usher protein -
B2H83_RS12545 () 2502222..2502896 - 675 WP_000677395.1 fimbria/pilus periplasmic chaperone -
B2H83_RS12550 () 2502977..2503519 - 543 WP_000830468.1 fimbrial protein -
B2H83_RS12555 () 2503812..2504093 - 282 WP_001324851.1 YehE family protein -
B2H83_RS12560 () 2504356..2505465 - 1110 WP_001005448.1 iron-sulfur cluster carrier protein ApbC -
B2H83_RS12565 () 2505597..2507630 + 2034 WP_129541943.1 methionine--tRNA ligase -
B2H83_RS12570 () 2507771..2511565 + 3795 WP_001215613.1 WGR and DUF4132 domain-containing protein -
B2H83_RS12575 () 2511575..2515207 + 3633 WP_129541944.1 DUF4132 domain-containing protein -
B2H83_RS12580 () 2515268..2515585 + 318 WP_000636923.1 hypothetical protein -
B2H83_RS12585 () 2516825..2517913 + 1089 WP_000074859.1 MoxR family ATPase -
B2H83_RS12590 () 2517924..2520203 + 2280 WP_001294423.1 hypothetical protein -
B2H83_RS12595 () 2520196..2521332 + 1137 WP_001292774.1 VWA domain-containing protein -
B2H83_RS12600 () 2521329..2523329 + 2001 WP_001317947.1 SWIM zinc finger family protein -
B2H83_RS12605 () 2523454..2523915 + 462 WP_001295429.1 YehR family lipoprotein -
B2H83_RS12610 () 2523956..2524426 - 471 WP_001295430.1 DUF1456 family protein -
B2H83_RS12615 () 2524473..2525192 - 720 WP_000598641.1 two-component system response regulator BtsR -
B2H83_RS12620 () 2525189..2526874 - 1686 WP_001295431.1 two-component regulatory system sensor histidine kinase BtsS -
B2H83_RS12625 () 2527096..2527827 + 732 WP_001240401.1 HTH-type transcriptional regulator MlrA -
B2H83_RS12630 () 2527887..2527994 + 108 WP_001216963.1 protein YohO -
B2H83_RS12635 () 2527975..2528706 - 732 WP_000783120.1 glycine betaine ABC transporter permease YehW -
B2H83_RS12640 () 2528711..2529637 - 927 WP_000569325.1 glycine betaine ABC transporter ATP binding protein YehX -
B2H83_RS12645 () 2529630..2530787 - 1158 WP_000221772.1 glycine betaine ABC transporter permease YehY -
B2H83_RS12650 () 2530794..2531711 - 918 WP_001130307.1 glycine betaine ABC transporter substrate-binding protein OsmF -
B2H83_RS12655 () 2531922..2534219 - 2298 WP_000871512.1 beta-glucosidase BglX -
B2H83_RS12660 () 2534415..2536130 + 1716 WP_000097369.1 D-lactate dehydrogenase -
B2H83_RS12665 () 2536168..2537097 - 930 WP_001367079.1 D-alanyl-D-alanine endopeptidase -
B2H83_RS12670 () 2537271..2537858 - 588 WP_001295454.1 YIP1 family protein -
B2H83_RS12675 () 2538028..2538606 + 579 WP_000365433.1 DedA family protein -
B2H83_RS12680 () 2538736..2539497 - 762 WP_000079523.1 SDR family oxidoreductase -
B2H83_RS12685 () 2539550..2540986 - 1437 WP_001078114.1 multidrug resistance outer membrane protein MdtQ -
B2H83_RS12690 () 2541210..2541293 + 84 WP_000691708.1 protein YohP -
B2H83_RS12695 () 2541666..2542613 - 948 WP_001264875.1 tRNA dihydrouridine(16) synthase DusC -
B2H83_RS12700 () 2542852..2543250 + 399 WP_129541945.1 CidA/LrgA family protein -
B2H83_RS12705 () 2543247..2543942 + 696 WP_000968208.1 CidB/LrgB family autolysis modulator -
B2H83_RS12710 () 2544072..2544956 + 885 WP_000553559.1 cytidine deaminase -
B2H83_RS12715 () 2545106..2545825 + 720 WP_000920064.1 outer membrane permeability protein SanA -
B2H83_RS12720 () 2545828..2546067 + 240 WP_000383096.1 DUF2542 family protein -
B2H83_RS12725 () 2546386..2547624 + 1239 WP_001136365.1 NAD-dependent dihydropyrimidine dehydrogenase subunit PreT -
B2H83_RS12730 () 2547618..2548853 + 1236 WP_000956043.1 NAD-dependent dihydropyrimidine dehydrogenase subunit PreA -
B2H83_RS12735 () 2548924..2549934 - 1011 WP_001275118.1 galactose/methyl galactoside ABC transporter permease MglC -
B2H83_RS12740 () 2549950..2551470 - 1521 WP_000255039.1 galactose/methyl galactoside ABC transporter ATP-binding protein MglA -
B2H83_RS12745 () 2551531..2552529 - 999 WP_001036964.1 galactose/glucose ABC transporter substrate-binding protein MglB -
B2H83_RS12750 () 2552809..2553849 - 1041 WP_000628660.1 HTH-type transcriptional regulator GalS -
B2H83_RS12755 () 2553991..2555148 - 1158 WP_000440895.1 DUF418 family protein -
B2H83_RS12760 () 2555165..2555833 - 669 WP_001139613.1 GTP cyclohydrolase I FolE -
B2H83_RS12765 () 2556091..2556927 + 837 WP_000425462.1 S-formylglutathione hydrolase -
B2H83_RS12770 () 2556959..2558950 - 1992 WP_129541946.1 catecholate siderophore receptor CirA -
B2H83_RS12780 () 2559243..2560712 - 1470 WP_000253273.1 lysine-specific permease -
B2H83_RS12785 () 2560917..2561798 - 882 WP_000548294.1 LysR family transcriptional regulator -
B2H83_RS12790 () 2561897..2562946 + 1050 WP_000182053.1 YeiH family protein -
B2H83_RS12795 () 2563020..2563877 + 858 WP_000873890.1 deoxyribonuclease IV -
B2H83_RS12800 () 2563881..2564969 + 1089 WP_000999819.1 sugar kinase -
B2H83_RS12805 () 2565025..2566275 - 1251 WP_000382941.1 NupC/NupG family nucleoside CNT transporter -
B2H83_RS12810 () 2566375..2567316 - 942 WP_000415455.1 ribosylpyrimidine nucleosidase -
B2H83_RS12815 () 2567446..2568144 + 699 WP_000658580.1 transcriptional regulator YeiL -
B2H83_RS12820 () 2568215..2569465 - 1251 WP_000353878.1 NupC/NupG family nucleoside CNT transporter -
B2H83_RS12825 () 2569559..2570497 - 939 WP_001292468.1 pseudouridine-5'-phosphate glycosidase -
B2H83_RS12830 () 2570485..2571426 - 942 WP_129541947.1 pseudouridine kinase -
B2H83_RS12835 () 2571850..2573541 - 1692 WP_000854469.1 PTS fructose transporter subunit IIBC -
B2H83_RS12840 () 2573558..2574496 - 939 WP_000091263.1 1-phosphofructokinase -
B2H83_RS12845 () 2574496..2575626 - 1131 WP_000487257.1 fused PTS fructose transporter subunit IIA/HPr protein -
B2H83_RS12850 () 2575994..2577175 + 1182 WP_000551969.1 sugar efflux transporter SetB -
B2H83_RS12855 () 2577172..2577426 - 255 WP_001349348.1 YkgJ family cysteine cluster protein -
B2H83_RS12860 () 2577581..2578153 + 573 WP_001136827.1 elongation factor P-like protein YeiP -
B2H83_RS12865 () 2578376..2579842 + 1467 WP_000848214.1 mannitol dehydrogenase family protein -
B2H83_RS12870 () 2579960..2580946 + 987 WP_000198822.1 zinc-binding GTPase YeiR -
B2H83_RS12875 () 2580985..2581698 + 714 WP_000594599.1 Kdo(2)-lipid A phosphotransferase -
B2H83_RS12880 () 2582110..2582676 + 567 WP_000241012.1 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase -
B2H83_RS12885 () 2582857..2584413 + 1557 WP_000470594.1 cyclic di-GMP phosphodiesterase -
B2H83_RS12890 () 2584495..2586309 + 1815 WP_001369843.1 extracellular solute-binding protein -
B2H83_RS12895 () 2586310..2587404 + 1095 WP_000501583.1 microcin C ABC transporter permease YejB -
B2H83_RS12900 () 2587404..2588429 + 1026 WP_000088916.1 ABC transporter permease -
B2H83_RS12905 () 2588431..2590020 + 1590 WP_000194928.1 microcin C ABC transporter ATP-binding protein YejF -
B2H83_RS12910 () 2590024..2590368 - 345 WP_000202798.1 YejG family protein -
B2H83_RS12915 () 2590701..2591891 - 1191 WP_000213360.1 multidrug efflux MFS transporter Bcr -
B2H83_RS12920 () 2591919..2592614 - 696 WP_001234850.1 16S rRNA pseudouridine(516) synthase RsuA -
B2H83_RS12925 () 2592763..2594523 + 1761 WP_000578076.1 DEAD/DEAH box helicase -
B2H83_RS12930 () 2594648..2594932 + 285 WP_000494183.1 50S ribosomal protein L25 -
B2H83_RS12935 () 2595071..2596078 - 1008 WP_000050789.1 nucleoid-associated protein YejK -
B2H83_RS12940 () 2596260..2596487 + 228 WP_001135667.1 YejL family protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance