MGE detailed information
MGE type: Conjugative plasmid MGE length: 142829 bp
Accession: NZ_CP019014 Location: 1..142829 Organism: Escherichia coli strain Ecol_AZ162 Replicon: plasmid pECAZ162_KPC
Accession: NZ_CP019014 Location: 1..142829 Organism: Escherichia coli strain Ecol_AZ162 Replicon: plasmid pECAZ162_KPC
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BE965_RS00675 () | 1..804 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BE965_RS00680 () | 804..1640 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| BE965_RS28860 () | 1747..1968 | - | 222 | Protein_2 | transposase zinc-binding domain-containing protein | - |
| BE965_RS00690 () | 2032..2736 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE965_RS00700 () | 3154..3525 | - | 372 | WP_004196359.1 | hypothetical protein | - |
| BE965_RS28020 () | 3650..3842 | - | 193 | Protein_5 | MFS transporter | - |
| BE965_RS00705 () | 3926..4081 | + | 156 | Protein_6 | chromate resistance protein | - |
| BE965_RS00710 () | 4437..5756 | + | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| BE965_RS00715 () | 6006..6887 | - | 882 | WP_004152396.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| BE965_RS00725 () | 7206..7985 | - | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| BE965_RS00730 () | 7982..9007 | - | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| BE965_RS00735 () | 9114..12143 | - | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| BE965_RS00740 () | 12253..13968 | + | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| BE965_RS00745 () | 14020..14394 | - | 375 | Protein_13 | Tn3 family transposase TnpA_Tn3 | Transposase |
| BE965_RS00750 () | 14455..15159 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE965_RS28030 () | 15209..17920 | + | 2712 | Protein_15 | Multifunctional conjugation protein TraI | Relaxase |
| BE965_RS28605 () | 17940..18686 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| BE965_RS00770 () | 18745..19605 | + | 861 | WP_000704528.1 | putative protein YcjY | VF |
| BE965_RS00775 () | 19708..20268 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| BE965_RS00780 () | 20397..20609 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| BE965_RS00785 () | 20854..21315 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| BE965_RS00790 () | 21361..21570 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| BE965_RS00795 () | 21608..22198 | + | 591 | WP_000766805.1 | DUF2726 domain-containing protein | - |
| BE965_RS00800 () | 22438..22698 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| BE965_RS00810 () | 22923..22997 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| BE965_RS00815 () | 22990..23847 | + | 858 | WP_000130647.1 | incFII family plasmid replication initiator RepA | - |
| BE965_RS00825 () | 24786..25439 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| BE965_RS28610 () | 25532..25789 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| BE965_RS00830 () | 25722..26123 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| BE965_RS00835 () | 26260..29157 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| BE965_RS00840 () | 29252..29857 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| BE965_RS00845 () | 29881..30630 | - | 750 | Protein_31 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| BE965_RS00850 () | 30619..31026 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| BE965_RS00855 () | 31164..32048 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| BE965_RS00860 () | 32080..33279 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| BE965_RS00865 () | 33385..34035 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| BE965_RS00870 () | 34067..34309 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| BE965_RS00875 () | 34351..35865 | - | 1515 | Protein_37 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| BE965_RS00885 () | 35931..36635 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE965_RS28615 () | 36716..36781 | - | 66 | Protein_39 | EAL domain-containing protein | - |
| BE965_RS00895 () | 36825..37130 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| BE965_RS00900 () | 37141..38346 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| BE965_RS00905 () | 38574..39578 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| BE965_RS00910 () | 39760..39963 | - | 204 | WP_064765192.1 | hypothetical protein | - |
| BE965_RS00920 () | 40160..40999 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| BE965_RS00925 () | 40993..41340 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| BE965_RS00930 () | 41546..42334 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| BE965_RS00935 () | 42465..42938 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| BE965_RS00940 () | 43096..44109 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| BE965_RS28620 () | 44312..44662 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| BE965_RS28865 () | 44788..44967 | + | 180 | Protein_50 | recombinase family protein | - |
| BE965_RS00955 () | 45008..45712 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE965_RS00960 () | 45938..46753 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| BE965_RS00970 () | 47100..48986 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| BE965_RS00975 () | 49027..49554 | + | 528 | WP_000178050.1 | iron transporter | - |
| BE965_RS00980 () | 49658..51037 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| BE965_RS00985 () | 51040..52323 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| BE965_RS00990 () | 52313..53443 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| BE965_RS00995 () | 53448..54143 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| BE965_RS01000 () | 54130..54615 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| BE965_RS01005 () | 54640..55125 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| BE965_RS01010 () | 55247..55777 | + | 531 | Protein_61 | histidine-type phosphatase | - |
| BE965_RS01020 () | 55835..56539 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE965_RS01025 () | 56564..57760 | + | 1197 | Protein_63 | IS3 family transposase | - |
| BE965_RS01030 () | 57782..58015 | + | 234 | Protein_64 | Tn3 family transposase | - |
| BE965_RS01035 () | 58092..58400 | + | 309 | Protein_65 | IS4 family transposase ISEc13 | Transposase |
| BE965_RS01040 () | 58459..59769 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| BE965_RS01045 () | 59762..60835 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| BE965_RS01050 () | 60841..61665 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| BE965_RS01055 () | 61676..62563 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| BE965_RS01060 () | 62553..63431 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| BE965_RS01065 () | 63562..64002 | - | 441 | Protein_71 | zinc-binding dehydrogenase | - |
| BE965_RS01070 () | 63976..64170 | + | 195 | WP_000796505.1 | hypothetical protein | - |
| BE965_RS01075 () | 64403..65293 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| BE965_RS01080 () | 65318..65698 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| BE965_RS01085 () | 65731..66696 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| BE965_RS01090 () | 66742..67494 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| BE965_RS01095 () | 68099..68383 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| BE965_RS01100 () | 68383..68658 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| BE965_RS01105 () | 68764..69057 | + | 294 | WP_001105060.1 | hypothetical protein | - |
| BE965_RS28040 () | 69092..69220 | - | 129 | Protein_80 | IS481 family transposase | - |
| BE965_RS01110 () | 69253..70422 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| BE965_RS01120 () | 70915..71222 | + | 308 | Protein_82 | type II toxin-antitoxin system ParD family antitoxin | - |
| BE965_RS01135 () | 71511..72208 | + | 698 | Protein_83 | IS1 family transposase IS1S | Transposase |
| BE965_RS01145 () | 72462..73484 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| BE965_RS01150 () | 73469..75034 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| BE965_RS01155 () | 75109..75525 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| BE965_RS01160 () | 75522..75752 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| BE965_RS01165 () | 76133..79927 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| BE965_RS01170 () | 79972..80388 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| BE965_RS01175 () | 80385..80615 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| BE965_RS01180 () | 80880..81380 | + | 501 | WP_000528932.1 | hypothetical protein | - |
| BE965_RS01185 () | 81393..82166 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| BE965_RS01190 () | 82377..83990 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| BE965_RS01195 () | 84021..84371 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| BE965_RS01200 () | 84368..84793 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| BE965_RS01205 () | 84855..86006 | + | 1152 | WP_031325939.1 | DUF3800 domain-containing protein | - |
| BE965_RS01210 () | 86040..86552 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| BE965_RS01215 () | 87098..87316 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| BE965_RS01220 () | 87318..87623 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| BE965_RS01225 () | 87624..88430 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| BE965_RS01230 () | 89204..89959 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| BE965_RS01235 () | 90547..91713 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| BE965_RS01240 () | 91713..92684 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| BE965_RS01255 () | 93551..94453 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| BE965_RS01260 () | 94457..94761 | + | 305 | Protein_105 | hypothetical protein | - |
| BE965_RS01265 () | 94838..95521 | + | 684 | WP_000086185.1 | DNA methylase | - |
| BE965_RS01270 () | 95522..95743 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| BE965_RS01275 () | 95757..96191 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| BE965_RS28625 () | 96242..97018 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| BE965_RS01290 () | 97558..97860 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| BE965_RS01295 () | 97907..98329 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| BE965_RS01300 () | 98326..98517 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| BE965_RS01315 () | 99552..99782 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| BE965_RS01320 () | 99834..101195 | + | 1362 | WP_000170728.1 | DUF3560 domain-containing protein | - |
| BE965_RS01325 () | 101242..101805 | + | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| BE965_RS01350 () | 102669..103196 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| BE965_RS01355 () | 103252..103485 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| BE965_RS01360 () | 103544..105502 | + | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| BE965_RS01365 () | 105557..105991 | + | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| BE965_RS01370 () | 105988..106707 | + | 720 | WP_001276234.1 | plasmid SOS inhibition protein A | - |
| BE965_RS28630 () | 106719..106907 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 106719..106943 | + | 225 | NuclAT_0 | - | - |
| - () | 106719..106943 | + | 225 | NuclAT_0 | - | - |
| - () | 106719..106943 | + | 225 | NuclAT_0 | - | - |
| - () | 106719..106943 | + | 225 | NuclAT_0 | - | - |
| - () | 106876..106941 | + | 66 | - | - | Antitoxin Detail |
| BE965_RS01375 () | 106987..107145 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| BE965_RS01395 () | 108064..108351 | + | 288 | WP_000107537.1 | hypothetical protein | - |
| BE965_RS01400 () | 108472..109293 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| BE965_RS01405 () | 109590..110237 | - | 648 | WP_000614282.1 | hypothetical protein | VF |
| BE965_RS01410 () | 110523..110906 | + | 384 | WP_001151564.1 | relaxosome protein TraM | - |
| BE965_RS01415 () | 111100..111786 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| BE965_RS01420 () | 111880..112107 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| BE965_RS01425 () | 112141..112503 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| BE965_RS01430 () | 112508..112819 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| BE965_RS01435 () | 112841..113407 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| BE965_RS01440 () | 113418..114122 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| BE965_RS01445 () | 114122..115549 | + | 1428 | WP_000146638.1 | conjugal transfer protein TraB | - |
| BE965_RS01450 () | 115539..116123 | + | 585 | WP_000002795.1 | conjugal transfer protein TraP | - |
| BE965_RS01455 () | 116077..116430 | + | 354 | WP_071528018.1 | conjugal transfer protein TrbD | - |
| BE965_RS01460 () | 116423..116674 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| BE965_RS01465 () | 116671..117186 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| BE965_RS01470 () | 117321..117542 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| BE965_RS01475 () | 117702..120329 | + | 2628 | WP_001064239.1 | type IV secretion system protein TraC | - |
| BE965_RS01480 () | 120326..120712 | + | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| BE965_RS01485 () | 120709..121341 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| BE965_RS01490 () | 121338..122330 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| BE965_RS01495 () | 122360..122665 | + | 306 | WP_000224411.1 | hypothetical protein | - |
| BE965_RS01500 () | 122674..123312 | + | 639 | WP_001080257.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| BE965_RS01510 () | 123490..124194 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE965_RS01515 () | 124260..124883 | + | 624 | Protein_146 | methyltransferase domain-containing protein | - |
| BE965_RS01520 () | 124937..125695 | + | 759 | WP_004196325.1 | hypothetical protein | - |
| BE965_RS01525 () | 125929..127227 | + | 1299 | WP_004196314.1 | nickel resistance membrane nickel efflux protein NirA | - |
| BE965_RS01530 () | 127333..127602 | + | 270 | WP_004196355.1 | nickel-sensing transcriptional repressor NcrB | - |
| BE965_RS01535 () | 127615..128745 | + | 1131 | WP_004196366.1 | Ni(II)/Co(II) efflux transporter permease subunit NcrC | - |
| BE965_RS01540 () | 128907..129329 | + | 423 | WP_032072095.1 | nickel resistance OB fold protein NcrY | - |
| BE965_RS01545 () | 129585..130925 | - | 1341 | WP_004196353.1 | ISNCY family transposase ISCARN112 | Transposase |
| BE965_RS01550 () | 131014..132546 | + | 1533 | WP_015065592.1 | IS3 family transposase ISKpn38 | Transposase |
| BE965_RS01555 () | 132980..135262 | - | 2283 | WP_162859354.1 | S8 family peptidase | - |
| BE965_RS01560 () | 135468..136508 | - | 1041 | WP_022644891.1 | ATP-binding protein | - |
| BE965_RS01570 () | 138067..138771 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BE965_RS01575 () | 138825..140183 | + | 1359 | Protein_158 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| BE965_RS01580 () | 140262..141266 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| BE965_RS01585 () | 141448..141624 | - | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| BE965_RS01595 () | 141954..142769 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|