MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 170854 bp
Accession: NZ_CP018073 Location: 1..170854 Organism: Enterococcus faecium strain VRE001 Replicon: plasmid unnamed3
Accession: NZ_CP018073 Location: 1..170854 Organism: Enterococcus faecium strain VRE001 Replicon: plasmid unnamed3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BOW68_RS16370 () | 177..812 | + | 636 | Protein_0 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| BOW68_RS16375 () | 826..2322 | + | 1497 | Protein_1 | PTS transporter subunit EIIC | - |
| BOW68_RS16380 () | 2335..2811 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| BOW68_RS17915 () | 2908..3018 | - | 111 | Protein_3 | transposase | - |
| BOW68_RS17750 () | 3308..4466 | - | 1159 | Protein_4 | IS3 family transposase | - |
| BOW68_RS16410 () | 5494..6795 | - | 1302 | WP_002302440.1 | ISL3 family transposase ISEfa11 | Transposase |
| BOW68_RS16415 () | 7081..7598 | + | 518 | Protein_6 | ClbS/DfsB family four-helix bundle protein | - |
| BOW68_RS16430 () | 9674..10759 | + | 1086 | WP_002301591.1 | tyrosine recombinase XerS | - |
| BOW68_RS16435 () | 10867..11820 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
| BOW68_RS16440 () | 11951..13201 | - | 1251 | WP_002301126.1 | PTS sugar transporter subunit IIC | - |
| BOW68_RS16445 () | 13220..14146 | - | 927 | WP_002298736.1 | PEP phosphonomutase | - |
| BOW68_RS16450 () | 14225..15220 | - | 996 | WP_002301128.1 | tagatose-bisphosphate aldolase | - |
| BOW68_RS16455 () | 15236..16405 | - | 1170 | WP_002301130.1 | SIS domain-containing protein | - |
| BOW68_RS16460 () | 16421..17155 | - | 735 | WP_002301131.1 | GntR family transcriptional regulator | - |
| BOW68_RS16475 () | 19657..20949 | - | 1293 | WP_002301811.1 | IS256 family transposase ISBsu2 | Transposase |
| BOW68_RS16480 () | 21223..21483 | - | 261 | WP_002313174.1 | hypothetical protein | - |
| BOW68_RS16485 () | 21734..22912 | + | 1179 | WP_002346943.1 | IS256 family transposase ISEf1 | Transposase |
| BOW68_RS16495 () | 23088..24260 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| BOW68_RS16500 () | 24596..24892 | + | 297 | WP_073120200.1 | IS3 family transposase ISEfa8 | Transposase |
| BOW68_RS17760 () | 24815..25639 | - | 825 | Protein_20 | IS3 family transposase ISEfa8 | Transposase |
| BOW68_RS16515 () | 25841..26236 | - | 396 | WP_002287876.1 | aspartate 1-decarboxylase | - |
| BOW68_RS16520 () | 26246..27094 | - | 849 | WP_002287875.1 | pantoate--beta-alanine ligase | - |
| BOW68_RS16525 () | 27109..27936 | - | 828 | WP_002287874.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| BOW68_RS16530 () | 27948..28808 | - | 861 | WP_002349114.1 | Rossmann-like and DUF2520 domain-containing protein | - |
| BOW68_RS16535 () | 29007..29201 | + | 195 | WP_002285758.1 | hypothetical protein | - |
| BOW68_RS16540 () | 29191..29544 | + | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| BOW68_RS16545 () | 29646..31193 | + | 1548 | WP_002296127.1 | IS66 family transposase ISRob1 | Transposase |
| BOW68_RS16550 () | 31273..31647 | + | 375 | Protein_28 | IS256 family transposase ISEfa13 | Transposase |
| BOW68_RS16555 () | 31987..32667 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| BOW68_RS16565 () | 33297..34469 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| BOW68_RS16570 () | 34599..35909 | - | 1311 | Protein_31 | Bifunctional AAC/APH | ARG |
| BOW68_RS16575 () | 35964..36140 | - | 177 | Protein_32 | IS6 family transposase | - |
| BOW68_RS16580 () | 36300..37337 | - | 1038 | WP_002303110.1 | IS3 family transposase ISSde10 | Transposase |
| BOW68_RS16585 () | 37334..37846 | - | 513 | WP_002303111.1 | IS3 family transposase ISPa31 | Transposase |
| BOW68_RS16590 () | 37916..38170 | - | 255 | Protein_35 | replication initiation protein | - |
| BOW68_RS16595 () | 38590..39909 | + | 1320 | WP_000202380.1 | IS1380 family transposase IS1678 | Transposase |
| BOW68_RS16600 () | 40529..41080 | - | 552 | WP_002303113.1 | DUF334 domain-containing protein | - |
| BOW68_RS16605 () | 41175..41555 | - | 381 | Protein_38 | IS6 family transposase IS1216V | Transposase |
| BOW68_RS16610 () | 41625..42305 | + | 681 | WP_002319817.1 | IS6 family transposase IS1297 | Transposase |
| BOW68_RS16615 () | 42333..42896 | + | 564 | WP_002304893.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| BOW68_RS16620 () | 42941..43108 | - | 168 | WP_000824191.1 | hypothetical protein | - |
| BOW68_RS16625 () | 43142..43441 | - | 300 | WP_000366408.1 | BRCT domain-containing protein | - |
| BOW68_RS16630 () | 43482..44099 | - | 618 | WP_073120208.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| BOW68_RS16635 () | 44424..44819 | - | 396 | WP_002304891.1 | hypothetical protein | - |
| BOW68_RS16640 () | 44899..47250 | - | 2352 | WP_000344083.1 | DUF1906 domain-containing protein | - |
| BOW68_RS16645 () | 47375..48064 | - | 690 | WP_000718009.1 | hypothetical protein | - |
| BOW68_RS16650 () | 48078..48530 | - | 453 | WP_000751236.1 | hypothetical protein | - |
| BOW68_RS16655 () | 48661..49341 | + | 681 | WP_002325565.1 | IS6 family transposase IS1216E | Transposase |
| BOW68_RS16660 () | 49443..50762 | - | 1320 | WP_002300494.1 | HAMP domain-containing histidine kinase | - |
| BOW68_RS16665 () | 50759..51412 | - | 654 | WP_002285815.1 | Transcriptional regulatory protein QseB | VF |
| BOW68_RS17765 () | 51700..52220 | + | 521 | Protein_51 | transposase | - |
| BOW68_RS16680 () | 52122..52838 | - | 717 | WP_002348630.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| BOW68_RS16685 () | 52888..53097 | - | 210 | WP_002302256.1 | hypothetical protein | - |
| BOW68_RS17920 () | 53374..54647 | + | 1274 | Protein_54 | ISL3 family transposase ISEfa11 | Transposase |
| BOW68_RS16700 () | 54754..55785 | - | 1032 | WP_002302261.1 | Spermidine/putrescine import ATP-binding protein PotA | VF |
| BOW68_RS16705 () | 55792..56622 | - | 831 | WP_002313180.1 | ABC transporter permease | - |
| BOW68_RS16710 () | 56619..57434 | - | 816 | WP_002330693.1 | ABC transporter permease subunit | - |
| BOW68_RS16715 () | 57431..58255 | - | 825 | WP_002302267.1 | alkaline phosphatase family protein | - |
| BOW68_RS16720 () | 58245..59345 | - | 1101 | WP_002347701.1 | extracellular solute-binding protein | - |
| BOW68_RS16725 () | 59523..60308 | + | 786 | WP_002302270.1 | histidinol phosphate phosphatase | - |
| BOW68_RS16730 () | 60341..60724 | + | 384 | WP_002330694.1 | hypothetical protein | - |
| BOW68_RS16735 () | 60800..60931 | + | 132 | WP_077828694.1 | peptidylprolyl isomerase | - |
| BOW68_RS16740 () | 60900..61136 | + | 237 | WP_002322470.1 | Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase | VF |
| BOW68_RS16750 () | 61214..62185 | - | 972 | WP_002302275.1 | radical SAM protein | - |
| BOW68_RS16755 () | 62837..64459 | + | 1623 | WP_002340465.1 | IS1182 family transposase ISEfa7 | Transposase |
| BOW68_RS16760 () | 64745..66121 | - | 1377 | WP_002301195.1 | ABC transporter permease | - |
| BOW68_RS16765 () | 66121..66777 | - | 657 | WP_002298083.1 | putative ABC transporter ATP-binding protein | VF |
| BOW68_RS16770 () | 66787..68064 | - | 1278 | WP_002301194.1 | ABC transporter permease | - |
| BOW68_RS17925 () | 68083..68238 | - | 156 | Protein_69 | 4Fe-4S binding protein | - |
| BOW68_RS16785 () | 68314..69476 | + | 1163 | WP_087121905.1 | IS3 family transposase ISEfa8 | Transposase |
| BOW68_RS16790 () | 69506..69955 | - | 450 | WP_002330699.1 | TlpA family protein disulfide reductase | - |
| BOW68_RS18130 () | 70111..70653 | - | 543 | WP_002298088.1 | hypothetical protein | - |
| BOW68_RS16805 () | 70927..72089 | + | 1163 | WP_099745858.1 | IS3 family transposase ISEfa8 | Transposase |
| BOW68_RS16810 () | 72195..72410 | + | 216 | Protein_74 | IS256 family transposase ISEf1 | Transposase |
| BOW68_RS17775 () | 72714..73193 | - | 480 | WP_002313278.1 | hypothetical protein | - |
| BOW68_RS16820 () | 73263..74171 | - | 909 | WP_002326839.1 | IS982 family transposase ISEfm1 | Transposase |
| BOW68_RS17940 () | 74282..74593 | - | 312 | Protein_77 | hypothetical protein | - |
| BOW68_RS16830 () | 74847..75401 | - | 555 | WP_002301108.1 | tyrosine-type recombinase/integrase | - |
| BOW68_RS16845 () | 77036..77848 | - | 813 | WP_002307497.1 | hypothetical protein | - |
| BOW68_RS16855 () | 78522..79694 | + | 1173 | WP_002316137.1 | IS256 family transposase IS256 | Transposase |
| BOW68_RS17780 () | 80331..80740 | - | 410 | Protein_81 | IS200-IS605 family transposase ISAac1 | Transposase |
| BOW68_RS16875 () | 80974..81837 | - | 864 | WP_002303163.1 | triphosphoribosyl-dephospho-CoA synthase CitG | - |
| BOW68_RS16880 () | 81830..82387 | - | 558 | WP_002305953.1 | citrate lyase holo-[acyl-carrier protein] synthase | - |
| BOW68_RS16885 () | 82384..83943 | - | 1560 | WP_002303161.1 | citrate lyase subunit alpha | - |
| BOW68_RS16890 () | 83936..84841 | - | 906 | WP_002303160.1 | citrate (pro-3S)-lyase subunit beta | - |
| BOW68_RS16895 () | 84846..85139 | - | 294 | WP_002303159.1 | citrate lyase acyl carrier protein | - |
| BOW68_RS16900 () | 85143..86156 | - | 1014 | WP_002303158.1 | [citrate (pro-3S)-lyase] ligase | - |
| BOW68_RS16905 () | 86182..87486 | - | 1305 | WP_002303157.1 | 2-hydroxycarboxylate transporter family protein | - |
| BOW68_RS16910 () | 87467..88654 | - | 1188 | WP_002303156.1 | NADP-dependent malic enzyme | - |
| BOW68_RS16915 () | 88842..89789 | + | 948 | WP_002303155.1 | DNA-binding transcriptional regulator | - |
| BOW68_RS16920 () | 90086..90634 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| BOW68_RS16925 () | 90635..91492 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| BOW68_RS16930 () | 91778..92065 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BOW68_RS16935 () | 92055..92384 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| BOW68_RS16940 () | 92461..92733 | - | 273 | WP_002305108.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| BOW68_RS16945 () | 92733..92996 | - | 264 | WP_002303154.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| BOW68_RS16950 () | 93102..93518 | - | 417 | WP_002303153.1 | hypothetical protein | - |
| BOW68_RS16955 () | 93524..94204 | - | 681 | WP_010729614.1 | IS6 family transposase IS1297 | Transposase |
| BOW68_RS16960 () | 94745..95935 | - | 1191 | WP_002314359.1 | IS256 family transposase ISLgar5 | Transposase |
| BOW68_RS16965 () | 96676..97035 | + | 360 | WP_073120210.1 | iron-sulfur cluster biosynthesis family protein | - |
| BOW68_RS16970 () | 97108..97926 | - | 819 | WP_002303335.1 | Cof-type HAD-IIB family hydrolase | - |
| BOW68_RS16975 () | 98340..98690 | - | 351 | WP_002324485.1 | GNAT family N-acetyltransferase | - |
| BOW68_RS16980 () | 98760..99713 | + | 954 | WP_010729620.1 | IS30 family transposase IS1252 | Transposase |
| BOW68_RS16985 () | 99909..100106 | + | 198 | WP_002293041.1 | cold-shock protein | - |
| BOW68_RS16990 () | 100213..101514 | - | 1302 | WP_002302440.1 | ISL3 family transposase ISEfa11 | Transposase |
| BOW68_RS16995 () | 101890..102453 | + | 564 | Protein_106 | IS30 family transposase IS1062 | Transposase |
| BOW68_RS17000 () | 102729..103013 | - | 285 | WP_002303603.1 | hypothetical protein | - |
| BOW68_RS17005 () | 103034..104404 | - | 1371 | WP_002324486.1 | DUF4357 domain-containing protein | - |
| BOW68_RS17010 () | 104623..105531 | + | 909 | WP_002326174.1 | IS982 family transposase ISEfm1 | Transposase |
| BOW68_RS17015 () | 106165..106482 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BOW68_RS17020 () | 106483..106737 | - | 255 | WP_002303208.1 | hypothetical protein | - |
| BOW68_RS17025 () | 107096..107500 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| BOW68_RS17030 () | 107517..108665 | + | 1149 | WP_002323589.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| BOW68_RS17035 () | 108888..109106 | - | 219 | Protein_114 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BOW68_RS17040 () | 109372..109566 | - | 195 | WP_002348857.1 | hypothetical protein | - |
| BOW68_RS18135 () | 109666..109752 | - | 87 | Protein_116 | single-stranded DNA-binding protein | - |
| BOW68_RS17045 () | 110918..111958 | + | 1041 | WP_002303636.1 | replication initiator protein A | - |
| BOW68_RS17050 () | 112782..113114 | + | 333 | WP_002323647.1 | hypothetical protein | - |
| BOW68_RS17060 () | 113733..114074 | + | 342 | WP_002295674.1 | DUF5406 domain-containing protein | - |
| BOW68_RS17065 () | 114311..115561 | - | 1251 | WP_002297404.1 | IS110 family transposase ISSpn10 | Transposase |
| BOW68_RS17070 () | 115971..118343 | + | 2373 | WP_002305801.1 | hypothetical protein | - |
| BOW68_RS17075 () | 118404..119873 | + | 1470 | WP_002353594.1 | toprim domain-containing protein | - |
| BOW68_RS17080 () | 119884..121893 | + | 2010 | WP_002303486.1 | DNA topoisomerase III | - |
| BOW68_RS18140 () | 122009..122158 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| BOW68_RS17090 () | 122239..122835 | + | 597 | WP_002303484.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| BOW68_RS17095 () | 122848..123747 | + | 900 | WP_002303483.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| BOW68_RS17100 () | 123750..123881 | + | 132 | WP_002301801.1 | single-stranded DNA-binding protein | - |
| BOW68_RS17105 () | 123903..124235 | + | 333 | WP_002305808.1 | single-stranded DNA-binding protein | - |
| BOW68_RS17110 () | 124280..124513 | + | 234 | WP_002303482.1 | hypothetical protein | - |
| BOW68_RS17115 () | 124672..124794 | - | 123 | WP_002295624.1 | putative holin-like toxin | - |
| BOW68_RS17120 () | 124984..125208 | + | 225 | WP_002305809.1 | hypothetical protein | - |
| BOW68_RS17130 () | 125651..125857 | + | 207 | WP_002305810.1 | hypothetical protein | - |
| BOW68_RS17135 () | 125857..126108 | + | 252 | WP_002300797.1 | hypothetical protein | - |
| BOW68_RS18145 () | 126124..126279 | + | 156 | WP_002300799.1 | hypothetical protein | - |
| BOW68_RS17140 () | 126289..126561 | + | 273 | WP_002300801.1 | hypothetical protein | - |
| BOW68_RS17150 () | 127006..127185 | + | 180 | WP_002300804.1 | hypothetical protein | - |
| BOW68_RS17155 () | 127244..127600 | + | 357 | WP_002311569.1 | hypothetical protein | - |
| BOW68_RS17165 () | 128569..129522 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
| BOW68_RS17170 () | 129643..129906 | + | 264 | WP_002300807.1 | uberolysin/carnocyclin family circular bacteriocin | - |
| BOW68_RS17180 () | 130278..131456 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| BOW68_RS17185 () | 131655..132608 | + | 954 | WP_002326066.1 | IS30 family transposase IS1252 | Transposase |
| BOW68_RS17190 () | 133055..133963 | + | 909 | WP_002332708.1 | IS982 family transposase ISEfm1 | Transposase |
| BOW68_RS17195 () | 133983..135905 | + | 1923 | Protein_143 | PTS sugar transporter subunit IIA | - |
| BOW68_RS17200 () | 135908..136363 | + | 456 | WP_002300835.1 | PTS sugar transporter subunit IIA | - |
| BOW68_RS17205 () | 136377..137705 | + | 1329 | WP_002300836.1 | PTS galactitol transporter subunit IIC | - |
| BOW68_RS17210 () | 137739..138023 | + | 285 | WP_002300838.1 | PTS sugar transporter subunit IIB | - |
| BOW68_RS17215 () | 138025..138540 | + | 516 | WP_002300840.1 | YjbQ family protein | - |
| BOW68_RS17220 () | 138556..139218 | + | 663 | WP_002300841.1 | Ribulose-phosphate 3-epimerase | VF |
| BOW68_RS17225 () | 139225..139797 | + | 573 | WP_002300842.1 | 3-hexulose-6-phosphate isomerase | VF |
| BOW68_RS17230 () | 139969..141516 | - | 1548 | WP_002303202.1 | IS66 family transposase ISRob1 | Transposase |
| BOW68_RS17235 () | 141618..141971 | - | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| BOW68_RS17240 () | 141961..142155 | - | 195 | WP_002285758.1 | hypothetical protein | - |
| BOW68_RS17245 () | 142337..143857 | - | 1521 | WP_002300843.1 | IS66 family transposase ISDeal1 | Transposase |
| BOW68_RS17255 () | 144100..144285 | - | 186 | WP_002305884.1 | IS66 family transposase ISEbi1 | Transposase |
| BOW68_RS17260 () | 144269..144451 | - | 183 | WP_002300846.1 | hypothetical protein | - |
| BOW68_RS17265 () | 144692..144910 | + | 219 | Protein_156 | IS256 family transposase ISLgar5 | Transposase |
| BOW68_RS17270 () | 145405..146004 | + | 600 | WP_002301839.1 | Tyrosine recombinase XerD | VF |
| BOW68_RS17275 () | 146068..146667 | + | 600 | WP_002322465.1 | bacteriophage abortive infection AbiH family protein | - |
| BOW68_RS17280 () | 146697..147348 | - | 652 | Protein_159 | IS6 family transposase IS1216V | Transposase |
| BOW68_RS17285 () | 147683..148555 | - | 873 | WP_002305879.1 | ROK family protein | - |
| BOW68_RS17290 () | 148819..150765 | - | 1947 | WP_002303302.1 | sucrose-specific PTS transporter subunit IIBC | - |
| BOW68_RS17295 () | 150950..152389 | + | 1440 | WP_002302078.1 | sucrose-6-phosphate hydrolase | - |
| BOW68_RS17300 () | 152391..153353 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
| BOW68_RS17320 () | 155192..155647 | + | 456 | WP_002301718.1 | IS200-IS605 family transposase ISAac3 | Transposase |
| BOW68_RS17945 () | 155912..156010 | + | 99 | Protein_166 | IS30 family transposase | - |
| BOW68_RS17330 () | 156233..156463 | - | 231 | WP_002289255.1 | resolvase | - |
| BOW68_RS17335 () | 156693..157511 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| BOW68_RS17340 () | 157672..158361 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| BOW68_RS17345 () | 158375..159877 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| BOW68_RS17350 () | 159890..160366 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| BOW68_RS17950 () | 160463..160573 | - | 111 | Protein_172 | transposase | - |
| BOW68_RS17375 () | 163058..164359 | - | 1302 | WP_002302440.1 | ISL3 family transposase ISEfa11 | Transposase |
| BOW68_RS17380 () | 164645..165163 | + | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| BOW68_RS17400 () | 167235..168318 | + | 1084 | Protein_176 | tyrosine recombinase XerS | - |
| BOW68_RS17405 () | 168421..169380 | - | 960 | WP_073120213.1 | IS30 family transposase IS1252 | Transposase |
| BOW68_RS17410 () | 169510..170760 | - | 1251 | WP_002301126.1 | PTS sugar transporter subunit IIC | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|