NZ_CP0158231..205221

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 205221 bp
Accession: NZ_CP015823        Location: 1..205221         Organism: Klebsiella pneumoniae isolate blood sample       Replicon: 2 plasmid 1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8N26_RS27610 () 527..1802 - 1276 Protein_0 DUF2254 domain-containing protein -
A8N26_RS27615 () 1865..3862 - 1998 Protein_1 choline BCCT transporter BetT -
A8N26_RS27620 () 4014..4711 - 698 Protein_2 IS1 family transposase IS1X2 Transposase
A8N26_RS27635 () 6200..6684 + 485 Protein_4 IS1 family transposase IS1X2 Transposase
A8N26_RS27640 () 6700..7242 + 543 Protein_5 ISL3 family transposase ISKpn25 Transposase
A8N26_RS27645 () 7538..7969 - 432 WP_004178091.1 silver-binding protein SilE -
A8N26_RS27650 () 8220..9695 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
A8N26_RS27655 () 9688..10368 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
A8N26_RS27660 () 10558..11943 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
A8N26_RS27665 () 11972..12325 + 354 WP_001246153.1 cation efflux system protein CusF -
A8N26_RS27670 () 12439..13731 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
A8N26_RS27675 () 13742..16888 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
A8N26_RS27680 () 16975..17415 + 441 WP_000758228.1 hypothetical protein -
A8N26_RS27685 () 17542..19989 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
A8N26_RS27690 () 20030..20227 + 198 WP_000843497.1 DUF2933 domain-containing protein -
A8N26_RS27695 () 20261..20998 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
A8N26_RS27700 () 21287..21736 - 450 WP_001023257.1 copper resistance protein -
A8N26_RS27705 () 21970..23787 + 1818 WP_004152083.1 multicopper oxidase PcoA -
A8N26_RS27710 () 23793..24683 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
A8N26_RS27715 () 24723..25103 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
A8N26_RS27720 () 25108..26037 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
A8N26_RS27725 () 26092..26772 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
A8N26_RS27730 () 26769..28169 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
A8N26_RS27735 () 28386..28820 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
A8N26_RS27740 () 29052..29231 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
A8N26_RS31360 () 29292..30912 - 1621 Protein_26 ISL3 family transposase -
A8N26_RS27760 () 30974..31483 + 510 WP_031944101.1 aquaporin -
A8N26_RS27765 () 31533..32030 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
A8N26_RS27770 () 32362..32688 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
A8N26_RS27775 () 32685..33398 + 714 WP_004152093.1 arsenical resistance protein ArsH -
A8N26_RS27780 () 33407..33952 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
A8N26_RS27785 () 34028..34390 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
A8N26_RS27790 () 34415..36165 + 1751 Protein_33 arsenical pump-driving ATPase -
A8N26_RS27795 () 36287..36823 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
A8N26_RS27800 () 36856..37281 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
A8N26_RS27805 () 37294..38583 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
A8N26_RS27810 () 38631..40382 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
A8N26_RS27815 () 40400..40762 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
A8N26_RS27820 () 40812..41162 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
A8N26_RS27825 () 41520..41789 + 270 WP_004152102.1 hypothetical protein -
A8N26_RS27830 () 41777..42352 + 576 WP_004152103.1 hypothetical protein -
A8N26_RS27835 () 42383..42877 + 495 WP_004152104.1 DNA-binding protein -
A8N26_RS27840 () 42921..43289 + 369 WP_004152105.1 hypothetical protein -
A8N26_RS27845 () 43323..43526 + 204 WP_004152106.1 hemolysin expression modulator Hha -
A8N26_RS27850 () 43575..43832 + 258 WP_004152107.1 hypothetical protein -
A8N26_RS27855 () 43908..44162 + 255 WP_004152108.1 hypothetical protein -
A8N26_RS27860 () 44338..44604 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
A8N26_RS27865 () 44592..45074 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
A8N26_RS27870 () 45286..46632 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
A8N26_RS31915 () 47133..48387 - 1255 Protein_50 IS3 family transposase ISKpn38 Transposase
A8N26_RS27885 () 48475..49437 - 963 WP_004152113.1 M48 family metalloprotease -
A8N26_RS27890 () 49424..50173 - 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
A8N26_RS27895 () 50411..50608 - 198 WP_004152115.1 hypothetical protein -
A8N26_RS27900 () 50608..53403 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
A8N26_RS27905 () 53518..54087 - 570 WP_004152117.1 Spore protein SP21 VF
A8N26_RS27910 () 54122..54403 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
A8N26_RS31920 () 54647..54910 - 264 WP_004118208.1 hypothetical protein -
A8N26_RS31925 () 54925..55188 + 264 WP_004118209.1 transposase -
A8N26_RS31930 () 55133..55249 + 117 Protein_59 transposase domain-containing protein -
A8N26_RS27925 () 55434..56131 + 698 Protein_60 IS1 family transposase IS1X2 Transposase
A8N26_RS27930 () 56390..57370 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
A8N26_RS27935 () 57952..58471 - 520 Protein_62 IS5 family transposase ISPst7 Transposase
A8N26_RS27940 () 58579..59448 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
A8N26_RS27945 () 59442..60452 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
A8N26_RS27950 () 60461..61288 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
A8N26_RS27955 () 61297..62160 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
A8N26_RS27960 () 62157..62984 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
A8N26_RS27965 () 63326..63634 + 309 Protein_68 IS5 family transposase ISThi1 Transposase
A8N26_RS27970 () 63840..64544 - 705 WP_004217321.1 IS6 family transposase IS26 Transposase
A8N26_RS27975 () 64607..65800 + 1194 Protein_70 Tn3 family transposase TnpA_ISSba14 Transposase
A8N26_RS27980 () 65848..66516 + 669 WP_044503635.1 IS6 family transposase IS26 Transposase
A8N26_RS27985 () 66706..67521 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
A8N26_RS27990 () 67672..68376 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
A8N26_RS27995 () 68498..69403 + 906 WP_000219391.1 hypothetical protein ARG
A8N26_RS28000 () 69400..70638 + 1239 WP_000004159.1 MFS transporter -
A8N26_RS28005 () 70638..71222 + 585 WP_001137892.1 TetR family transcriptional regulator -
A8N26_RS28015 () 71715..72479 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
A8N26_RS32655 () 72597..72662 - 66 Protein_78 EAL domain-containing protein -
A8N26_RS28020 () 72706..73011 - 306 WP_000130000.1 hypothetical protein Relaxase
A8N26_RS28025 () 73022..74227 - 1206 WP_000184001.1 chromate efflux transporter -
A8N26_RS28030 () 74383..74586 - 204 WP_000376616.1 hypothetical protein -
A8N26_RS28035 () 74714..75553 - 840 WP_000259031.1 Dihydropteroate synthase ARG
A8N26_RS28040 () 75547..75894 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
A8N26_RS28045 () 76058..76849 - 792 WP_001206356.1 Streptomycin 3''-adenylyltransferase ARG
A8N26_RS31950 () 76855..77145 - 291 WP_001336345.1 DUF1010 domain-containing protein -
A8N26_RS28055 () 77257..77754 - 498 WP_001083725.1 Dihydrofolate reductase ARG
A8N26_RS28060 () 77899..78912 + 1014 WP_000845039.1 IS91 family transposase ISAzo26 Transposase
A8N26_RS31960 () 79115..79465 + 351 WP_000454193.1 DUF3330 domain-containing protein -
A8N26_RS28075 () 79591..80151 + 561 WP_000147567.1 Tn3 family transposase TnpR_TnAs3 Transposase
A8N26_RS28080 () 80154..83120 + 2967 WP_001138064.1 Tn3 family transposase TnpA_TnAs3 Transposase
A8N26_RS28085 () 83187..83564 + 378 WP_000656305.1 GNAT family N-acetyltransferase -
A8N26_RS28090 () 83765..84424 - 660 WP_000412211.1 Chloramphenicol acetyltransferase ARG
A8N26_RS28095 () 84703..85400 + 698 Protein_93 IS1 family transposase IS1R Transposase
A8N26_RS30805 () 85393..85632 + 240 WP_176716597.1 His-Xaa-Ser system protein HxsD -
A8N26_RS28100 () 85632..87020 + 1389 WP_004152560.1 His-Xaa-Ser system radical SAM maturase HxsB -
A8N26_RS28105 () 87013..88125 + 1113 WP_000005560.1 His-Xaa-Ser system radical SAM maturase HxsC -
A8N26_RS30810 () 88122..88757 + 636 WP_004118217.1 His-Xaa-Ser repeat protein HxsA -
A8N26_RS28115 () 89305..89691 + 387 WP_020956879.1 IS66 family transposase ISSgsp1 Transposase
A8N26_RS28120 () 89688..90035 + 348 WP_004152557.1 IS66 family transposase ISCfr14 Transposase
A8N26_RS28125 () 90085..91622 + 1538 Protein_100 IS66 family transposase ISCfr14 Transposase
A8N26_RS28130 () 91660..92037 + 378 Protein_101 IS66 family transposase ISEc22 Transposase
A8N26_RS28135 () 93858..95591 - 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
A8N26_RS28140 () 95599..96546 - 948 WP_004118225.1 acetamidase/formamidase family protein -
A8N26_RS28145 () 96591..98195 - 1605 WP_004152278.1 ABC transporter substrate-binding protein -
A8N26_RS28150 () 98208..99128 - 921 WP_004118227.1 ABC transporter permease -
A8N26_RS28155 () 99128..99976 - 849 WP_004152279.1 ABC transporter permease -
A8N26_RS28160 () 99973..100566 - 594 WP_004118229.1 ANTAR domain-containing protein -
A8N26_RS28165 () 100563..101690 - 1128 WP_004118840.1 transporter substrate-binding protein -
A8N26_RS28170 () 101975..102142 - 168 WP_004118231.1 integrase -
A8N26_RS32660 () 102071..102283 + 213 WP_161989521.1 hypothetical protein -
A8N26_RS28175 () 102284..102769 + 486 Protein_111 IS21 family transposase ISEc62 Transposase
A8N26_RS28180 () 103245..103766 + 522 WP_004118235.1 putative RNA polymerase sigma factor FecI VF
A8N26_RS28185 () 103763..104716 + 954 WP_004118237.1 fec operon regulator FecR -
A8N26_RS28190 () 104802..107126 + 2325 WP_004152280.1 Fe(3+) dicitrate transport protein FecA -
A8N26_RS28195 () 107171..108073 + 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
A8N26_RS28200 () 108070..109068 + 999 WP_004118243.1 Fe(3+) dicitrate transport system permease protein FecC VF
A8N26_RS28205 () 109065..110021 + 957 WP_004152281.1 Fe(3+) dicitrate transport system permease protein FecD VF
A8N26_RS28210 () 110022..110789 + 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
A8N26_RS28215 () 110888..111181 + 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
A8N26_RS31965 () 111256..111483 + 228 Protein_120 IS66 family transposase -
A8N26_RS30815 () 111512..111799 - 288 WP_165765869.1 EAL domain-containing protein -
A8N26_RS28220 () 112133..113143 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
A8N26_RS28230 () 113604..114686 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
A8N26_RS28235 () 114808..117882 + 3075 WP_004152287.1 beta-galactosidase -
A8N26_RS28240 () 117934..119187 + 1254 WP_003846917.1 lactose permease -
A8N26_RS28245 () 119279..120248 + 970 Protein_126 IS5 family transposase IS903B Transposase
A8N26_RS28250 () 120893..123202 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
A8N26_RS28255 () 123206..124522 + 1317 WP_004152291.1 ATP-binding protein -
A8N26_RS28260 () 124519..126714 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
A8N26_RS28275 () 128161..129018 - 858 WP_004152292.1 incFII family plasmid replication initiator RepA -
A8N26_RS30820 () 129011..129088 - 78 WP_004171457.1 RepA leader peptide Tap -
A8N26_RS28280 () 129305..129583 - 279 WP_004199332.1 replication regulatory protein RepA -
A8N26_RS28285 () 129904..130383 - 480 WP_009485932.1 Phospholipase D VF
A8N26_RS28290 () 130724..131002 - 279 WP_004152296.1 bacteriocin immunity protein -
A8N26_RS28295 () 131004..133325 - 2322 WP_004178051.1 klebicin B-related nuclease bacteriocin -
A8N26_RS28305 () 133682..134227 + 546 WP_004152300.1 hypothetical protein -
A8N26_RS28310 () 134442..134789 - 348 WP_004152301.1 hypothetical protein -
A8N26_RS28315 () 134809..135405 - 597 WP_004178053.1 fertility inhibition protein FinO -
A8N26_RS28320 () 135563..136288 - 726 WP_004152303.1 type-F conjugative transfer system pilin acetylase TraX -
A8N26_RS28325 () 136368..141629 - 5262 WP_004153029.1 Multifunctional conjugation protein TraI Relaxase
A8N26_RS28330 () 141629..143938 - 2310 Protein_141 type IV conjugative transfer system coupling protein TraD -
A8N26_RS28335 () 144298..145029 - 732 WP_004152629.1 complement resistance protein TraT -
A8N26_RS28340 () 145219..145746 - 528 WP_004153030.1 hypothetical protein -
A8N26_RS28345 () 145752..148601 - 2850 WP_004152627.1 conjugal transfer mating pair stabilization protein TraG -
A8N26_RS28350 () 148601..149971 - 1371 WP_004178055.1 conjugal transfer protein TraH -
A8N26_RS28355 () 149958..150386 - 429 WP_004152689.1 hypothetical protein -
A8N26_RS28360 () 150379..150951 - 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
A8N26_RS28365 () 150923..151162 - 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
A8N26_RS28370 () 151173..151925 - 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
A8N26_RS28375 () 151946..152272 - 327 WP_004152685.1 hypothetical protein -
A8N26_RS28385 () 152500..152736 - 237 WP_004152683.1 conjugal transfer protein TrbE -
A8N26_RS28390 () 152768..154723 - 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
A8N26_RS28395 () 154771..155409 - 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
A8N26_RS28400 () 155422..156414 - 993 WP_004178057.1 conjugal transfer pilus assembly protein TraU -
A8N26_RS28405 () 156425..157051 - 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
A8N26_RS28410 () 157051..157440 - 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
A8N26_RS28415 () 157440..160079 - 2640 WP_004152592.1 type IV secretion system protein TraC -
A8N26_RS28420 () 160151..160549 - 399 WP_004153071.1 hypothetical protein -
A8N26_RS28425 () 160845..161249 - 405 WP_004152594.1 hypothetical protein -
A8N26_RS28430 () 161316..161633 - 318 WP_004152595.1 hypothetical protein -
A8N26_RS28435 () 161634..161852 - 219 WP_004171484.1 hypothetical protein -
A8N26_RS28440 () 161876..162166 - 291 WP_004152596.1 hypothetical protein -
A8N26_RS28445 () 162171..162581 - 411 WP_004152597.1 lipase chaperone -
A8N26_RS30835 () 162713..163282 - 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
A8N26_RS28450 () 163305..163901 - 597 WP_004152599.1 conjugal transfer protein TraP -
A8N26_RS28455 () 163894..165318 - 1425 WP_004152600.1 conjugal transfer protein TraB -
A8N26_RS28460 () 165318..166058 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
A8N26_RS28465 () 166045..166611 - 567 WP_015060016.1 type IV conjugative transfer system protein TraE -
A8N26_RS28470 () 166631..166936 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
A8N26_RS28475 () 166950..167318 - 369 WP_004152496.1 type IV conjugative transfer system pilin TraA -
A8N26_RS28480 () 167372..167758 - 387 WP_004152495.1 TraY domain-containing protein -
A8N26_RS28485 () 167837..168523 - 687 WP_004152494.1 transcriptional regulator TraJ family protein -
A8N26_RS28490 () 168697..169095 - 399 WP_004152493.1 relaxosome protein TraM -
A8N26_RS28495 () 169517..170002 + 486 WP_001568108.1 hypothetical protein VF
A8N26_RS30840 () 170035..170364 - 330 WP_011977736.1 hypothetical protein -
A8N26_RS28500 () 170397..171218 - 822 WP_004152492.1 DUF945 domain-containing protein -
A8N26_RS28505 () 172038..172871 - 834 WP_004152751.1 type I restriction-modification system subunit M -
A8N26_RS28510 () 172922..173068 - 147 WP_004152750.1 hypothetical protein -
A8N26_RS28515 () 173163..173510 - 348 WP_004152749.1 hypothetical protein -
A8N26_RS28520 () 173567..173920 - 354 WP_004152748.1 hypothetical protein -
A8N26_RS28525 () 174550..174900 - 351 WP_004153414.1 hypothetical protein -
A8N26_RS28530 () 174897..175169 - 273 WP_004152661.1 hypothetical protein -
A8N26_RS28535 () 175217..175576 - 360 WP_004152660.1 hypothetical protein -
A8N26_RS31975 () 175687..176010 - 324 WP_004199367.1 hypothetical protein -
A8N26_RS28545 () 176014..176736 - 723 WP_004152658.1 plasmid SOS inhibition protein A -
A8N26_RS28550 () 176733..177164 - 432 WP_004152657.1 conjugation system SOS inhibitor PsiB -
A8N26_RS28555 () 177210..179219 - 2010 WP_004152656.1 ParB/RepB/Spo0J family partition protein -
A8N26_RS28560 () 179288..179530 - 243 WP_004152655.1 DUF905 domain-containing protein -
A8N26_RS28565 () 179578..180090 - 513 WP_004152654.1 single-stranded DNA-binding protein -
A8N26_RS28575 () 180921..181484 - 564 WP_004161464.1 methyltransferase -
A8N26_RS28580 () 181532..182886 - 1355 Protein_191 DUF3560 domain-containing protein -
A8N26_RS28585 () 182938..183168 - 231 WP_001568051.1 hypothetical protein -
A8N26_RS28590 () 183260..183487 - 228 WP_004152790.1 hypothetical protein -
A8N26_RS28595 () 184271..184588 - 318 WP_004118473.1 hypothetical protein -
A8N26_RS28600 () 184623..184877 - 255 WP_004152754.1 DNA polymerase III subunit theta -
A8N26_RS28605 () 185114..185539 - 426 WP_004118478.1 antirestriction protein -
A8N26_RS28610 () 186060..186290 - 231 WP_004152753.1 hypothetical protein -
A8N26_RS28615 () 186524..188011 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
A8N26_RS28620 () 188414..188839 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
A8N26_RS28625 () 188839..190110 + 1272 WP_004152715.1 Y-family DNA polymerase -
A8N26_RS30895 () 190189..190404 + 216 Protein_201 type II toxin-antitoxin system Phd/YefM family antitoxin -
A8N26_RS28630 () 190427..191625 - 1199 Protein_202 IS200-IS605 family transposase IS609 Transposase
A8N26_RS28635 () 193062..194033 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
A8N26_RS28640 () 194033..195199 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF
A8N26_RS28645 () 195951..196961 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
A8N26_RS28650 () 197678..198418 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
A8N26_RS28655 () 199562..200509 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
A8N26_RS30920 () 200536..200847 - 312 WP_071527918.1 EAL domain-containing protein -
A8N26_RS28660 () 200867..201835 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
A8N26_RS30925 () 202508..202765 - 258 WP_004197688.1 hypothetical protein -
A8N26_RS30930 () 203367..204821 + 1455 WP_020444838.1 putative cyclic di-GMP phosphodiesterase PdeB VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance