MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 157282 bp
Accession: NZ_CP015410 Location: 830811..988092 Organism: Enterococcus faecalis strain KB1 Replicon: chromosome
Accession: NZ_CP015410 Location: 830811..988092 Organism: Enterococcus faecalis strain KB1 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A4V06_RS03950 () | 825938..826267 | + | 330 | WP_002356367.1 | cyclic-di-AMP receptor | - |
| A4V06_RS03955 () | 826269..827219 | + | 951 | WP_002384059.1 | DNA polymerase III subunit delta' | - |
| A4V06_RS03960 () | 827336..828175 | + | 840 | WP_002356371.1 | stage 0 sporulation family protein | - |
| A4V06_RS03965 () | 828168..828515 | + | 348 | WP_002356372.1 | DNA replication initiation control protein YabA | - |
| A4V06_RS03970 () | 828627..829499 | + | 873 | WP_002359438.1 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | - |
| A4V06_RS03975 () | 829514..830176 | + | 663 | WP_002356375.1 | ATP-binding cassette domain-containing protein | - |
| A4V06_RS03980 () | 830160..830918 | + | 759 | WP_002380776.1 | iron export ABC transporter permease subunit FetB | - |
| A4V06_RS03985 () | 831044..832162 | + | 1119 | WP_002380775.1 | DNA polymerase IV | - |
| A4V06_RS03990 () | 832207..832803 | - | 597 | WP_002356379.1 | anaerobic ribonucleoside-triphosphate reductase activating protein | - |
| A4V06_RS03995 () | 832836..835019 | - | 2184 | WP_002392852.1 | anaerobic ribonucleoside-triphosphate reductase | - |
| A4V06_RS04000 () | 835425..836192 | + | 768 | WP_002356382.1 | ABC transporter ATP-binding protein | - |
| A4V06_RS04005 () | 836182..838278 | + | 2097 | WP_065535910.1 | ABC transporter permease | - |
| A4V06_RS04010 () | 838482..838631 | + | 150 | WP_002356384.1 | teichoic acid D-Ala incorporation-associated protein DltX | - |
| A4V06_RS04015 () | 838646..840166 | + | 1521 | WP_002356385.1 | D-alanine--D-alanyl carrier protein ligase | VF |
| A4V06_RS04020 () | 840163..841368 | + | 1206 | WP_002382500.1 | Peptidoglycan O-acetyltransferase | VF |
| A4V06_RS04025 () | 841401..841637 | + | 237 | WP_002356389.1 | D-alanine--poly(phosphoribitol) ligase subunit DltC | - |
| A4V06_RS04030 () | 841637..842911 | + | 1275 | WP_002356390.1 | D-alanyl-lipoteichoic acid biosynthesis protein DltD | - |
| A4V06_RS04035 () | 843124..844206 | + | 1083 | WP_002367214.1 | M42 family metallopeptidase | - |
| A4V06_RS04040 () | 844227..845018 | + | 792 | WP_002362504.1 | DUF975 family protein | - |
| A4V06_RS04045 () | 845164..845904 | + | 741 | WP_002356393.1 | MBL fold metallo-hydrolase | - |
| A4V06_RS04050 () | 845937..846941 | + | 1005 | WP_002356394.1 | Lipoate-protein ligase LplJ | VF |
| A4V06_RS04055 () | 847070..848401 | + | 1332 | WP_065536091.1 | IS1182 family transposase ISEfa7 | Transposase |
| A4V06_RS04060 () | 849116..849805 | + | 690 | WP_002381418.1 | O-methyltransferase | - |
| A4V06_RS04065 () | 850046..850609 | + | 564 | WP_002392855.1 | peroxiredoxin | - |
| A4V06_RS04070 () | 850706..852388 | + | 1683 | WP_002362507.1 | FAD-dependent oxidoreductase | - |
| A4V06_RS04075 () | 852488..853078 | - | 591 | WP_002380740.1 | hypothetical protein | - |
| A4V06_RS04085 () | 853199..853732 | - | 534 | WP_010774685.1 | 3'-5' exonuclease | - |
| A4V06_RS04090 () | 853766..854521 | - | 756 | WP_002365059.1 | exodeoxyribonuclease III | - |
| A4V06_RS04095 () | 854728..855642 | + | 915 | WP_002380738.1 | Gfo/Idh/MocA family oxidoreductase | - |
| A4V06_RS04100 () | 855714..856616 | + | 903 | WP_002356404.1 | UDP-N-acetylenolpyruvoylglucosamine reductase | VF |
| A4V06_RS04105 () | 856680..858277 | + | 1598 | Protein_759 | glycosyltransferase family 39 protein | - |
| A4V06_RS04110 () | 858425..859063 | - | 639 | WP_065535911.1 | CBS domain-containing protein | - |
| A4V06_RS04115 () | 859349..859501 | + | 153 | WP_002356408.1 | 50S ribosomal protein L33 | - |
| A4V06_RS04120 () | 859522..859692 | + | 171 | WP_002356409.1 | preprotein translocase subunit SecE | - |
| A4V06_RS04125 () | 859817..860362 | + | 546 | WP_002384070.1 | transcription termination/antitermination protein NusG | - |
| A4V06_RS04130 () | 860473..861360 | + | 888 | WP_002380736.1 | alpha/beta hydrolase | - |
| A4V06_RS04135 () | 861453..862175 | - | 723 | WP_002372307.1 | MurR/RpiR family transcriptional regulator | - |
| A4V06_RS04140 () | 862253..863881 | + | 1629 | WP_065535912.1 | peptide ABC transporter substrate-binding protein | - |
| A4V06_RS04145 () | 863895..864998 | + | 1104 | WP_065535913.1 | M20/M25/M40 family metallo-hydrolase | - |
| A4V06_RS04150 () | 864995..865840 | + | 846 | WP_002362525.1 | M55 family metallopeptidase | - |
| A4V06_RS04155 () | 865905..866777 | - | 873 | WP_002380735.1 | L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha | - |
| A4V06_RS04160 () | 866800..867468 | - | 669 | WP_002414070.1 | L-serine ammonia-lyase, iron-sulfur-dependent subunit beta | - |
| A4V06_RS04165 () | 867844..869340 | + | 1497 | WP_002380734.1 | putative ABC transporter ATP-binding protein YheS | ARG |
| A4V06_RS04170 () | 869463..869885 | + | 423 | WP_002356424.1 | 50S ribosomal protein L11 | - |
| A4V06_RS04175 () | 869997..870686 | + | 690 | WP_002356425.1 | 50S ribosomal protein L1 | - |
| A4V06_RS04180 () | 871009..871509 | + | 501 | WP_002356426.1 | 50S ribosomal protein L10 | - |
| A4V06_RS04185 () | 871572..871940 | + | 369 | WP_002356427.1 | 50S ribosomal protein L7/L12 | - |
| A4V06_RS04190 () | 872190..872372 | - | 183 | Protein_776 | LPXTG cell wall anchor domain-containing protein | - |
| A4V06_RS04195 () | 872448..873128 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| A4V06_RS04200 () | 873170..873400 | + | 231 | WP_065535914.1 | hypothetical protein | - |
| A4V06_RS04205 () | 873393..873623 | + | 231 | WP_065535915.1 | type III secretion system protein PrgM | - |
| A4V06_RS04210 () | 873647..873961 | + | 315 | WP_065535916.1 | hypothetical protein | - |
| A4V06_RS15140 () | 873965..874102 | + | 138 | WP_157108314.1 | hypothetical protein | - |
| A4V06_RS04215 () | 874127..874447 | + | 321 | WP_065535917.1 | hypothetical protein | - |
| A4V06_RS04220 () | 874518..874739 | + | 222 | WP_065535918.1 | hypothetical protein | - |
| A4V06_RS04225 () | 874732..875004 | + | 273 | WP_010711009.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| A4V06_RS04230 () | 875185..875670 | + | 486 | WP_065535919.1 | DUF3801 domain-containing protein | - |
| A4V06_RS04235 () | 875670..877481 | + | 1812 | WP_065535920.1 | type IV secretory system conjugative DNA transfer family protein | - |
| A4V06_RS04240 () | 877641..878393 | + | 753 | WP_065535921.1 | Fic family protein | - |
| A4V06_RS04245 () | 878498..879061 | + | 564 | WP_065535922.1 | hypothetical protein | - |
| A4V06_RS04250 () | 879100..879573 | + | 474 | WP_065535923.1 | single-stranded DNA-binding protein | - |
| A4V06_RS04255 () | 879685..879975 | + | 291 | WP_065535924.1 | hypothetical protein | - |
| A4V06_RS04260 () | 880372..884922 | + | 4551 | WP_157108315.1 | DUF3991 domain-containing protein | - |
| A4V06_RS04265 () | 884981..885283 | + | 303 | WP_065535925.1 | hypothetical protein | - |
| A4V06_RS04270 () | 885628..885945 | + | 318 | WP_080476186.1 | plasmid mobilization relaxosome protein MobC | - |
| A4V06_RS04275 () | 885999..886679 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| A4V06_RS04280 () | 886727..888382 | - | 1656 | Protein_795 | hypothetical protein | VF |
| A4V06_RS15145 () | 889074..889193 | + | 120 | Protein_796 | transposase | - |
| A4V06_RS04295 () | 889930..890124 | - | 195 | WP_065535928.1 | hypothetical protein | - |
| A4V06_RS04300 () | 890118..890405 | - | 288 | WP_065535929.1 | hypothetical protein | - |
| A4V06_RS04305 () | 890457..890834 | - | 378 | Protein_799 | Aggregation substance | VF |
| A4V06_RS04310 () | 891452..891601 | - | 150 | WP_157662389.1 | IS3 family transposase | - |
| A4V06_RS04315 () | 892032..892568 | - | 537 | WP_065535931.1 | Asp23/Gls24 family envelope stress response protein | - |
| A4V06_RS04320 () | 892601..892789 | - | 189 | WP_065535932.1 | DUF2273 domain-containing protein | - |
| A4V06_RS04325 () | 892806..893372 | - | 567 | WP_065535933.1 | alkaline shock response membrane anchor protein AmaP | - |
| A4V06_RS04330 () | 894771..895805 | - | 1035 | WP_065535934.1 | YdcF family protein | - |
| A4V06_RS04345 () | 897216..898415 | - | 1200 | WP_065535935.1 | ABC transporter permease | - |
| A4V06_RS04350 () | 898412..899095 | - | 684 | WP_065535936.1 | putative ABC transporter ATP-binding protein YknY | VF |
| A4V06_RS04355 () | 899092..900309 | - | 1218 | WP_065535937.1 | efflux RND transporter periplasmic adaptor subunit | - |
| A4V06_RS04360 () | 900302..900790 | - | 489 | WP_065535938.1 | hypothetical protein | - |
| A4V06_RS04365 () | 900792..902176 | - | 1385 | Protein_809 | hypothetical protein | - |
| A4V06_RS04370 () | 902173..902598 | - | 426 | WP_065535939.1 | hypothetical protein | - |
| A4V06_RS04375 () | 902588..902860 | - | 273 | WP_065535940.1 | hypothetical protein | - |
| A4V06_RS04380 () | 902861..903130 | - | 270 | WP_065535941.1 | DUF2089 family protein | - |
| A4V06_RS04385 () | 903347..903478 | - | 132 | WP_065535942.1 | enterocin L50 family leaderless bacteriocin | - |
| A4V06_RS04390 () | 903498..903632 | - | 135 | WP_061101451.1 | enterocin L50 family leaderless bacteriocin | - |
| A4V06_RS04400 () | 904315..904959 | - | 645 | WP_198158935.1 | C39 family peptidase | - |
| A4V06_RS04405 () | 905017..906048 | - | 1032 | WP_065535945.1 | M23 family metallopeptidase | - |
| A4V06_RS04410 () | 906630..907033 | + | 404 | Protein_817 | hypothetical protein | - |
| A4V06_RS04415 () | 907160..907504 | - | 345 | WP_065535946.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| A4V06_RS04420 () | 907498..907761 | - | 264 | WP_065535947.1 | PbsX family transcriptional regulator | Antitoxin Detail |
| A4V06_RS04425 () | 907870..909372 | - | 1503 | Protein_820 | relaxase/mobilization nuclease domain-containing protein | - |
| A4V06_RS04430 () | 910492..911736 | - | 1245 | WP_089413444.1 | aminoacyltransferase | - |
| A4V06_RS15155 () | 912447..912602 | - | 156 | WP_157108316.1 | hypothetical protein | - |
| A4V06_RS04435 () | 912599..912805 | - | 207 | WP_065535949.1 | hypothetical protein | - |
| A4V06_RS04440 () | 912850..913074 | - | 225 | WP_065535950.1 | hypothetical protein | - |
| A4V06_RS15160 () | 913114..913275 | - | 162 | WP_157108317.1 | hypothetical protein | - |
| A4V06_RS04450 () | 913594..913848 | - | 255 | WP_065535952.1 | hypothetical protein | - |
| A4V06_RS04455 () | 913861..914097 | - | 237 | WP_002402118.1 | DUF3850 domain-containing protein | - |
| A4V06_RS04460 () | 914118..914438 | - | 321 | Protein_828 | PcfU | - |
| A4V06_RS04465 () | 914444..915025 | - | 582 | WP_065535953.1 | thermonuclease family protein | - |
| A4V06_RS04470 () | 915234..915743 | - | 510 | Protein_830 | single-stranded DNA-binding protein | - |
| A4V06_RS04475 () | 915864..916145 | + | 282 | WP_002402124.1 | hypothetical protein | - |
| A4V06_RS04480 () | 916177..916452 | - | 276 | WP_002402126.1 | helix-turn-helix transcriptional regulator | - |
| A4V06_RS04485 () | 916449..916808 | - | 360 | WP_002402127.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| A4V06_RS04490 () | 916936..917280 | - | 345 | WP_080476188.1 | hypothetical protein | - |
| A4V06_RS04495 () | 917240..918742 | - | 1503 | WP_065535955.1 | relaxase/mobilization nuclease domain-containing protein | - |
| A4V06_RS04500 () | 918744..919130 | - | 387 | WP_065535956.1 | plasmid mobilization relaxosome protein MobC | - |
| A4V06_RS04510 () | 919354..919644 | - | 291 | WP_065535957.1 | hypothetical protein | - |
| A4V06_RS04515 () | 919628..921301 | - | 1674 | WP_065535958.1 | hypothetical protein | - |
| A4V06_RS04520 () | 921361..921840 | - | 480 | WP_065535959.1 | hypothetical protein | - |
| A4V06_RS04525 () | 921843..926876 | - | 5034 | WP_065535960.1 | hypothetical protein | - |
| A4V06_RS15350 () | 926906..927061 | - | 156 | WP_198158932.1 | hypothetical protein | - |
| A4V06_RS04530 () | 927071..928273 | - | 1203 | WP_065535961.1 | toprim domain-containing protein | - |
| A4V06_RS04535 () | 928358..928987 | - | 630 | WP_065535962.1 | hypothetical protein | - |
| A4V06_RS15170 () | 928941..929180 | - | 240 | WP_135952869.1 | hypothetical protein | - |
| A4V06_RS04545 () | 929407..930732 | - | 1326 | WP_065535964.1 | hypothetical protein | - |
| A4V06_RS04550 () | 930719..931000 | - | 282 | WP_065535965.1 | hypothetical protein | - |
| A4V06_RS04555 () | 931018..931695 | - | 678 | WP_065535966.1 | hypothetical protein | - |
| A4V06_RS04560 () | 931980..933755 | - | 1776 | WP_198158934.1 | group II intron reverse transcriptase/maturase | - |
| A4V06_RS04565 () | 934473..934985 | - | 513 | WP_065535967.1 | hypothetical protein | - |
| A4V06_RS04570 () | 935109..935789 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| A4V06_RS04580 () | 935844..938840 | + | 2997 | Protein_851 | C protein alpha-antigen | VF |
| A4V06_RS15175 () | 938981..939127 | - | 147 | Protein_852 | transposase | - |
| A4V06_RS04585 () | 939190..939465 | - | 276 | WP_080476190.1 | IS3 family transposase | - |
| A4V06_RS04590 () | 939839..939955 | - | 117 | WP_080476220.1 | IS3 family transposase | - |
| A4V06_RS15180 () | 940039..940218 | - | 180 | WP_157779255.1 | helix-turn-helix domain containing protein | - |
| A4V06_RS04595 () | 940307..940565 | - | 259 | Protein_856 | hypothetical protein | VF |
| A4V06_RS04600 () | 941282..942484 | + | 1203 | WP_065535968.1 | YSIRK-targeted surface antigen transcriptional regulator | - |
| A4V06_RS04605 () | 942920..943438 | - | 519 | Protein_858 | sulfite exporter TauE/SafE family protein | - |
| A4V06_RS04610 () | 943493..944173 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| A4V06_RS04615 () | 944248..944916 | - | 669 | Protein_860 | radical SAM/SPASM domain-containing protein | - |
| A4V06_RS04620 () | 944992..945672 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| A4V06_RS04625 () | 945726..945986 | + | 261 | Protein_862 | SPASM domain-containing protein | - |
| A4V06_RS04630 () | 945983..946168 | + | 186 | Protein_863 | sulfite exporter TauE/SafE family protein | - |
| A4V06_RS04635 () | 946241..946921 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| A4V06_RS04640 () | 947200..947961 | - | 762 | WP_002355208.1 | HTH-type transcriptional regulator GlvR | VF |
| A4V06_RS04645 () | 948160..948750 | + | 591 | WP_002386047.1 | dihydrofolate reductase family protein | - |
| A4V06_RS04650 () | 948864..950249 | + | 1386 | WP_029644748.1 | TrkH family potassium uptake protein | - |
| A4V06_RS04655 () | 950270..951433 | + | 1164 | WP_002355211.1 | cation:proton antiporter | - |
| A4V06_RS04660 () | 951562..952002 | + | 441 | WP_002355212.1 | CopY/TcrY family copper transport repressor | - |
| A4V06_RS04665 () | 952018..954504 | + | 2487 | WP_002379951.1 | heavy metal translocating P-type ATPase | - |
| A4V06_RS04670 () | 954526..954732 | + | 207 | WP_002355215.1 | heavy-metal-associated domain-containing protein | - |
| A4V06_RS04675 () | 954777..956147 | - | 1371 | WP_065535971.1 | hypothetical protein | - |
| A4V06_RS04680 () | 956147..956536 | - | 390 | WP_002358356.1 | GntR family transcriptional regulator | - |
| A4V06_RS04685 () | 956686..958014 | + | 1329 | WP_002358357.1 | C1 family peptidase | - |
| A4V06_RS04690 () | 958059..958679 | - | 621 | WP_002364981.1 | flavin reductase family protein | - |
| A4V06_RS04695 () | 958701..959675 | - | 975 | WP_002355221.1 | ring-cleaving dioxygenase | - |
| A4V06_RS04700 () | 959958..960293 | + | 336 | WP_002362950.1 | multidrug resistance protein SMR | - |
| A4V06_RS04705 () | 960290..960601 | + | 312 | WP_002355223.1 | multidrug efflux SMR transporter | - |
| A4V06_RS04710 () | 960697..961743 | - | 1047 | WP_002380011.1 | chitinase | - |
| A4V06_RS04715 () | 961786..962370 | - | 585 | WP_002355225.1 | lytic polysaccharide monooxygenase | - |
| A4V06_RS04720 () | 962645..963379 | + | 735 | WP_002355227.1 | acyl-ACP thioesterase | - |
| A4V06_RS04725 () | 963430..964263 | + | 834 | WP_002358361.1 | DUF72 domain-containing protein | - |
| A4V06_RS04730 () | 964280..964816 | + | 537 | WP_002355230.1 | haloacid dehalogenase | - |
| A4V06_RS04735 () | 964839..966191 | - | 1353 | WP_002391510.1 | aspartate kinase | - |
| A4V06_RS04740 () | 966378..967064 | + | 687 | WP_002355232.1 | HAD family phosphatase | - |
| A4V06_RS04745 () | 967250..968986 | + | 1737 | WP_002355233.1 | septation ring formation regulator EzrA | - |
| A4V06_RS04750 () | 969112..970257 | + | 1146 | WP_002355234.1 | cysteine desulfurase | - |
| A4V06_RS04755 () | 970310..971002 | - | 693 | WP_065535972.1 | Transcriptional regulatory protein SrrA | VF |
| A4V06_RS04760 () | 970999..972342 | - | 1344 | WP_002385380.1 | HAMP domain-containing histidine kinase | - |
| A4V06_RS04765 () | 972666..973337 | + | 672 | Protein_890 | DUF4822 domain-containing protein | - |
| A4V06_RS04770 () | 973441..974772 | - | 1332 | WP_065536091.1 | IS1182 family transposase ISEfa7 | Transposase |
| A4V06_RS04775 () | 974870..975193 | + | 324 | Protein_892 | DUF4822 domain-containing protein | - |
| A4V06_RS04780 () | 975378..976343 | + | 966 | WP_002361155.1 | DUF4822 domain-containing protein | - |
| A4V06_RS04785 () | 976562..977605 | + | 1044 | WP_002393708.1 | DUF4822 domain-containing protein | - |
| A4V06_RS04790 () | 977779..978583 | + | 805 | Protein_895 | ankyrin repeat domain-containing protein | - |
| A4V06_RS04795 () | 978635..979846 | + | 1212 | WP_002393706.1 | amidohydrolase family protein | - |
| A4V06_RS04800 () | 979956..980375 | - | 420 | WP_002355245.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| A4V06_RS04805 () | 980372..980611 | - | 240 | WP_002358371.1 | addiction module antitoxin | - |
| A4V06_RS04810 () | 980712..981524 | - | 813 | WP_002393705.1 | alpha/beta hydrolase | - |
| A4V06_RS04815 () | 981499..983091 | - | 1593 | WP_065535973.1 | PucR family transcriptional regulator | - |
| A4V06_RS04820 () | 983214..986225 | + | 3012 | WP_002355249.1 | DUF1116 domain-containing protein | - |
| A4V06_RS04825 () | 986218..987051 | + | 834 | WP_002355250.1 | DUF2877 domain-containing protein | - |
| A4V06_RS04830 () | 987061..988314 | + | 1254 | WP_002355251.1 | MFS transporter | - |
| A4V06_RS04835 () | 988449..989387 | + | 939 | WP_002355252.1 | carbamate kinase | - |
| A4V06_RS04840 () | 989394..990614 | + | 1221 | WP_002355253.1 | dicarboxylate/amino acid:cation symporter | - |
| A4V06_RS04845 () | 990704..991765 | + | 1062 | WP_010708246.1 | ureidoglycolate dehydrogenase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|