MGE detailed information

MGE type: Conjugative plasmid        MGE length: 202696 bp
Accession: NZ_CP015393        Location: 1..202696         Organism: Klebsiella pneumoniae strain CR14       Replicon: plasmid pCR14_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6P37_RS27370 () 632..1012 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
A6P37_RS27375 () 1017..1946 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
A6P37_RS27380 () 2001..2681 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
A6P37_RS27385 () 2678..4078 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
A6P37_RS27390 () 4295..4729 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
A6P37_RS27395 () 4961..5140 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
A6P37_RS27400 () 5201..6821 - 1621 Protein_7 ISL3 family transposase -
A6P37_RS27405 () 6883..7392 + 510 WP_031944101.1 aquaporin -
A6P37_RS27410 () 7442..7939 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
A6P37_RS27415 () 8271..8597 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
A6P37_RS27420 () 8594..9307 + 714 WP_004152093.1 arsenical resistance protein ArsH -
A6P37_RS27425 () 9316..9861 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
A6P37_RS27430 () 9937..10299 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
A6P37_RS27435 () 10324..12074 + 1751 Protein_14 arsenical pump-driving ATPase -
A6P37_RS27440 () 12196..12732 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
A6P37_RS27445 () 12765..13190 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
A6P37_RS27450 () 13203..14492 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
A6P37_RS27455 () 14540..16291 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
A6P37_RS27460 () 16309..16671 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
A6P37_RS27465 () 16721..17071 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
A6P37_RS27470 () 17429..17698 + 270 WP_004152102.1 hypothetical protein -
A6P37_RS27475 () 17686..18261 + 576 WP_004152103.1 hypothetical protein -
A6P37_RS27480 () 18292..18786 + 495 WP_004152104.1 DNA-binding protein -
A6P37_RS27485 () 18830..19198 + 369 WP_004152105.1 hypothetical protein -
A6P37_RS27490 () 19232..19435 + 204 WP_004152106.1 hemolysin expression modulator Hha -
A6P37_RS27495 () 19484..19741 + 258 WP_004152107.1 hypothetical protein -
A6P37_RS27500 () 19817..20071 + 255 WP_004152108.1 hypothetical protein -
A6P37_RS27505 () 20247..20513 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
A6P37_RS27510 () 20501..20983 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
A6P37_RS27515 () 21195..22541 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
A6P37_RS31440 () 23042..24296 - 1255 Protein_31 IS3 family transposase ISKpn38 Transposase
A6P37_RS27530 () 24384..25346 - 963 WP_004152113.1 M48 family metalloprotease -
A6P37_RS27535 () 25333..26082 - 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
A6P37_RS27545 () 26320..26517 - 198 WP_004152115.1 hypothetical protein -
A6P37_RS27550 () 26517..29312 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
A6P37_RS27555 () 29427..29996 - 570 WP_004152117.1 Spore protein SP21 VF
A6P37_RS27560 () 30031..30312 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
A6P37_RS31445 () 30556..30819 - 264 WP_004118208.1 hypothetical protein -
A6P37_RS31450 () 30834..31097 + 264 WP_004118209.1 transposase -
A6P37_RS31455 () 31042..31158 + 117 Protein_40 transposase domain-containing protein -
A6P37_RS27570 () 31343..32040 + 698 Protein_41 IS1 family transposase IS1X2 Transposase
A6P37_RS27575 () 32299..33279 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
A6P37_RS27590 () 33861..34380 - 520 Protein_43 IS5 family transposase ISPst7 Transposase
A6P37_RS27595 () 34488..35357 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
A6P37_RS27600 () 35351..36361 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
A6P37_RS27605 () 36370..37197 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
A6P37_RS27610 () 37206..38069 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
A6P37_RS27615 () 38066..38893 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
A6P37_RS27620 () 39235..39543 + 309 Protein_49 IS5 family transposase ISThi1 Transposase
A6P37_RS27625 () 39749..40453 - 705 WP_004217321.1 IS6 family transposase IS26 Transposase
A6P37_RS27635 () 40516..41709 + 1194 Protein_51 Tn3 family transposase TnpA_ISSba14 Transposase
A6P37_RS27640 () 41788..42792 + 1005 WP_000427623.1 IS110 family transposase IS4321R Transposase
A6P37_RS27645 () 43090..43332 + 243 WP_071527925.1 EAL domain-containing protein -
A6P37_RS31460 () 43361..43588 - 228 Protein_54 IS66 family transposase -
A6P37_RS27650 () 43663..43956 - 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
A6P37_RS27655 () 44055..44822 - 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
A6P37_RS27660 () 44823..45779 - 957 WP_004152281.1 Fe(3+) dicitrate transport system permease protein FecD VF
A6P37_RS27665 () 45776..46774 - 999 WP_004118243.1 Fe(3+) dicitrate transport system permease protein FecC VF
A6P37_RS27670 () 46771..47673 - 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
A6P37_RS27675 () 47718..50042 - 2325 WP_004152280.1 Fe(3+) dicitrate transport protein FecA -
A6P37_RS27680 () 50128..51081 - 954 WP_004118237.1 fec operon regulator FecR -
A6P37_RS27685 () 51078..51599 - 522 WP_004118235.1 putative RNA polymerase sigma factor FecI VF
A6P37_RS27690 () 52075..52560 - 486 Protein_63 IS21 family transposase ISEc62 Transposase
A6P37_RS32165 () 52561..52773 - 213 WP_161989521.1 hypothetical protein -
A6P37_RS27695 () 52702..52869 + 168 WP_004118231.1 integrase -
A6P37_RS27700 () 53154..54281 + 1128 WP_004118840.1 transporter substrate-binding protein -
A6P37_RS27705 () 54278..54871 + 594 WP_004118229.1 ANTAR domain-containing protein -
A6P37_RS27710 () 54868..55716 + 849 WP_004152279.1 ABC transporter permease -
A6P37_RS27715 () 55716..56636 + 921 WP_004118227.1 ABC transporter permease -
A6P37_RS27720 () 56649..58253 + 1605 WP_004152278.1 ABC transporter substrate-binding protein -
A6P37_RS27725 () 58298..59245 + 948 WP_004118225.1 acetamidase/formamidase family protein -
A6P37_RS27730 () 59253..60986 + 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
A6P37_RS27735 () 62807..63184 - 378 Protein_73 IS66 family transposase ISEc22 Transposase
A6P37_RS27740 () 63222..64759 - 1538 Protein_74 IS66 family transposase ISCfr14 Transposase
A6P37_RS27745 () 64809..65156 - 348 WP_004152557.1 IS66 family transposase ISCfr14 Transposase
A6P37_RS27750 () 65153..65539 - 387 WP_020956879.1 IS66 family transposase ISSgsp1 Transposase
A6P37_RS27755 () 66087..66722 - 636 WP_004118217.1 His-Xaa-Ser repeat protein HxsA -
A6P37_RS27760 () 66719..67831 - 1113 WP_000005560.1 His-Xaa-Ser system radical SAM maturase HxsC -
A6P37_RS27765 () 67824..69212 - 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
A6P37_RS27770 () 69212..69484 - 273 WP_000333416.1 His-Xaa-Ser system protein HxsD -
A6P37_RS27775 () 69961..70110 + 150 Protein_81 IS3 family transposase IS2 Transposase
A6P37_RS27780 () 70125..70822 - 698 Protein_82 IS1 family transposase IS1R Transposase
A6P37_RS27795 () 71101..71760 + 660 WP_000412211.1 Chloramphenicol acetyltransferase ARG
A6P37_RS27800 () 71961..72338 - 378 WP_000656305.1 GNAT family N-acetyltransferase -
A6P37_RS27805 () 72649..73653 - 1005 WP_000427623.1 IS110 family transposase IS4321R Transposase
A6P37_RS27810 () 73881..75086 + 1206 WP_000184001.1 chromate efflux transporter -
A6P37_RS27815 () 75097..75402 + 306 WP_000130000.1 hypothetical protein Relaxase
A6P37_RS32170 () 75446..75511 + 66 Protein_88 EAL domain-containing protein -
A6P37_RS27830 () 75629..76393 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
A6P37_RS27840 () 76886..77470 - 585 WP_001137892.1 TetR family transcriptional regulator -
A6P37_RS27845 () 77470..78708 - 1239 WP_000004159.1 MFS transporter -
A6P37_RS27850 () 78705..79610 - 906 WP_000219391.1 hypothetical protein ARG
A6P37_RS27855 () 79732..80400 - 669 WP_044503635.1 IS6 family transposase IS26 Transposase
A6P37_RS27860 () 80692..81696 - 1005 WP_000427623.1 IS110 family transposase IS4321R Transposase
A6P37_RS27865 () 82100..83110 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
A6P37_RS27875 () 83571..84653 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
A6P37_RS27880 () 84775..87849 + 3075 WP_004152287.1 beta-galactosidase -
A6P37_RS27885 () 87901..89154 + 1254 WP_003846917.1 lactose permease -
A6P37_RS27890 () 89246..90215 + 970 Protein_99 IS5 family transposase IS903B Transposase
A6P37_RS27895 () 90860..93169 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
A6P37_RS27900 () 93173..94489 + 1317 WP_004152291.1 ATP-binding protein -
A6P37_RS27905 () 94486..96681 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
A6P37_RS27915 () 96904..97884 - 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
A6P37_RS27930 () 99328..100185 - 858 WP_004152386.1 incFII family plasmid replication initiator RepA -
A6P37_RS27935 () 100178..100255 - 78 WP_004171450.1 RepA leader peptide Tap -
A6P37_RS27940 () 100487..100756 - 270 WP_013609506.1 replication regulatory protein RepA -
A6P37_RS27945 () 100874..101353 - 480 WP_014343478.1 Phospholipase D VF
A6P37_RS27950 () 101529..101837 - 309 WP_004152383.1 hypothetical protein -
A6P37_RS27955 () 101834..102484 - 651 WP_004152382.1 DUF2726 domain-containing protein -
A6P37_RS27960 () 102540..103184 - 645 WP_004153014.1 hypothetical protein -
A6P37_RS31480 () 103234..103836 - 603 WP_015060010.1 hypothetical protein -
A6P37_RS27970 () 103997..104590 - 594 WP_004152380.1 fertility inhibition protein FinO -
A6P37_RS27975 () 104662..105387 - 726 WP_004152379.1 type-F conjugative transfer system pilin acetylase TraX -
A6P37_RS27980 () 105468..110729 - 5262 WP_077274557.1 Multifunctional conjugation protein TraI Relaxase
A6P37_RS27985 () 110729..113041 - 2313 Protein_115 type IV conjugative transfer system coupling protein TraD -
A6P37_RS32175 () 113170..113859 - 690 WP_004198206.1 hypothetical protein -
A6P37_RS27995 () 114051..114782 - 732 WP_004152622.1 complement resistance protein TraT -
A6P37_RS28000 () 114966..115514 - 549 WP_004152623.1 conjugal transfer entry exclusion protein TraS -
A6P37_RS28005 () 115527..118376 - 2850 WP_004152624.1 conjugal transfer mating pair stabilization protein TraG -
A6P37_RS28010 () 118376..119755 - 1380 WP_004165169.1 conjugal transfer protein TraH -
A6P37_RS28015 () 119733..120176 - 444 WP_004152679.1 F-type conjugal transfer protein TrbF -
A6P37_RS28020 () 120222..120779 - 558 WP_004152678.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
A6P37_RS28025 () 120751..120990 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
A6P37_RS28030 () 121001..121753 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
A6P37_RS28035 () 121774..122100 - 327 WP_004152676.1 hypothetical protein -
A6P37_RS28040 () 122113..122361 - 249 WP_004152675.1 hypothetical protein -
A6P37_RS28045 () 122339..122593 - 255 WP_004152674.1 conjugal transfer protein TrbE -
A6P37_RS28050 () 122625..124580 - 1956 WP_004152673.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
A6P37_RS28055 () 124639..125277 - 639 WP_004152672.1 type-F conjugative transfer system pilin assembly protein TrbC -
A6P37_RS28060 () 125290..126279 - 990 WP_011977785.1 conjugal transfer pilus assembly protein TraU -
A6P37_RS28065 () 126276..126665 - 390 WP_004152508.1 hypothetical protein -
A6P37_RS28070 () 126707..127333 - 627 WP_004152507.1 type-F conjugative transfer system protein TraW -
A6P37_RS28075 () 127333..127722 - 390 WP_004152506.1 type-F conjugative transfer system protein TrbI -
A6P37_RS28080 () 127722..130361 - 2640 WP_004152505.1 type IV secretion system protein TraC -
A6P37_RS28085 () 130433..130831 - 399 WP_011977783.1 hypothetical protein -
A6P37_RS28090 () 130839..131228 - 390 WP_004153076.1 hypothetical protein -
A6P37_RS28095 () 131271..131675 - 405 WP_004152503.1 hypothetical protein -
A6P37_RS28100 () 131742..132053 - 312 WP_004152502.1 hypothetical protein -
A6P37_RS28105 () 132054..132272 - 219 WP_004152501.1 hypothetical protein -
A6P37_RS28110 () 132378..132788 - 411 WP_004152499.1 hypothetical protein -
A6P37_RS28115 () 132920..133504 - 585 WP_004161368.1 type IV conjugative transfer system lipoprotein TraV -
A6P37_RS28120 () 133618..135042 - 1425 WP_062628050.1 conjugal transfer protein TraB -
A6P37_RS28125 () 135042..135782 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
A6P37_RS28130 () 135769..136074 - 306 Protein_144 type IV conjugative transfer system protein TraE -
A6P37_RS28135 () 136080..137288 - 1209 WP_001339197.1 IS4 family transposase IS10R Transposase
A6P37_RS28145 () 137395..137673 - 279 Protein_146 hypothetical protein -
A6P37_RS28150 () 137693..137998 - 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
A6P37_RS28155 () 138012..138380 - 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
A6P37_RS28160 () 138434..138805 - 372 WP_004208838.1 TraY domain-containing protein -
A6P37_RS28165 () 138889..139575 - 687 WP_011977735.1 transcriptional regulator TraJ family protein -
A6P37_RS28170 () 139798..140190 - 393 WP_004178062.1 relaxosome protein TraM -
A6P37_RS28175 () 140624..141109 + 486 WP_004178063.1 hypothetical protein VF
A6P37_RS28180 () 141142..141471 - 330 WP_011977736.1 hypothetical protein -
A6P37_RS28185 () 141504..142325 - 822 WP_004178064.1 DUF945 domain-containing protein -
A6P37_RS28205 () 143159..143572 - 414 WP_004152722.1 helix-turn-helix domain-containing protein -
A6P37_RS28210 () 143573..143851 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
A6P37_RS28215 () 143841..144161 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
A6P37_RS28220 () 144242..144466 - 225 WP_004152719.1 hypothetical protein -
A6P37_RS28225 () 144477..144689 - 213 WP_004152718.1 hypothetical protein -
A6P37_RS28230 () 144750..145106 - 357 WP_004152717.1 hypothetical protein -
A6P37_RS28250 () 145742..146092 - 351 WP_004152758.1 hypothetical protein -
A6P37_RS28255 () 146089..146361 - 273 WP_004152759.1 hypothetical protein -
A6P37_RS28260 () 147061..147222 - 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
A6P37_RS28265 () 147294..148373 + 1080 WP_004220208.1 IS481 family transposase ISKpn28 Transposase
A6P37_RS28275 () 148551..148925 - 375 WP_004152638.1 hypothetical protein -
A6P37_RS28280 () 148981..149307 - 327 WP_004152639.1 hypothetical protein -
A6P37_RS28285 () 149304..150032 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
A6P37_RS28290 () 150029..150460 - 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
A6P37_RS28295 () 150527..152563 - 2037 WP_004178066.1 ParB/RepB/Spo0J family partition protein -
A6P37_RS28300 () 152633..152881 - 249 WP_004152643.1 DUF905 domain-containing protein -
A6P37_RS28305 () 152930..153472 - 543 WP_004152644.1 single-stranded DNA-binding protein -
A6P37_RS28320 () 154248..154811 - 564 WP_004152645.1 methyltransferase -
A6P37_RS28325 () 154859..156214 - 1356 WP_004178068.1 DUF3560 domain-containing protein -
A6P37_RS28330 () 156266..156496 - 231 WP_004198570.1 hypothetical protein -
A6P37_RS28335 () 156588..156815 - 228 WP_004178072.1 hypothetical protein -
A6P37_RS28350 () 157597..157914 - 318 WP_004118473.1 hypothetical protein -
A6P37_RS28355 () 157949..158203 - 255 WP_004152754.1 DNA polymerase III subunit theta -
A6P37_RS28360 () 158440..158865 - 426 WP_004118478.1 antirestriction protein -
A6P37_RS28365 () 159386..159616 - 231 WP_004152753.1 hypothetical protein -
A6P37_RS28370 () 159850..161337 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
A6P37_RS28380 () 161740..162165 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
A6P37_RS28385 () 162165..163436 + 1272 WP_004152715.1 Y-family DNA polymerase -
A6P37_RS28390 () 163515..163730 + 216 Protein_183 type II toxin-antitoxin system Phd/YefM family antitoxin -
A6P37_RS28395 () 163753..164951 - 1199 Protein_184 IS200-IS605 family transposase IS609 Transposase
A6P37_RS28410 () 166388..167359 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
A6P37_RS28415 () 167359..168525 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF
A6P37_RS28420 () 169277..170287 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
A6P37_RS28430 () 171004..171744 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
A6P37_RS28440 () 172888..173835 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
A6P37_RS28445 () 173862..174173 - 312 WP_071527918.1 EAL domain-containing protein -
A6P37_RS28450 () 174193..175161 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
A6P37_RS28455 () 175834..176091 - 258 WP_004197688.1 hypothetical protein -
A6P37_RS28460 () 176693..178147 + 1455 WP_020444838.1 putative cyclic di-GMP phosphodiesterase PdeB VF
A6P37_RS28465 () 179130..180407 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
A6P37_RS28470 () 180470..182467 - 1998 WP_004178088.1 choline BCCT transporter BetT -
A6P37_RS28475 () 182619..183316 - 698 Protein_196 IS1 family transposase IS1X2 Transposase
A6P37_RS28485 () 184805..185289 + 485 Protein_198 IS1 family transposase IS1X2 Transposase
A6P37_RS28490 () 185305..185847 + 543 Protein_199 ISL3 family transposase ISKpn25 Transposase
A6P37_RS28495 () 186143..186574 - 432 WP_004178091.1 silver-binding protein SilE -
A6P37_RS28500 () 186825..188300 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
A6P37_RS28505 () 188293..188973 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
A6P37_RS28510 () 189163..190548 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
A6P37_RS28515 () 190577..190930 + 354 WP_001246153.1 cation efflux system protein CusF -
A6P37_RS28520 () 191044..192336 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
A6P37_RS28525 () 192347..195493 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
A6P37_RS28530 () 195580..196020 + 441 WP_000758228.1 hypothetical protein -
A6P37_RS28535 () 196147..198594 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
A6P37_RS28540 () 198635..198832 + 198 WP_000843497.1 DUF2933 domain-containing protein -
A6P37_RS28545 () 198866..199603 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
A6P37_RS28550 () 199892..200341 - 450 WP_001023257.1 copper resistance protein -
A6P37_RS28555 () 200575..202392 + 1818 WP_000925242.1 multicopper oxidase PcoA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance