MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 204959 bp
Accession: NZ_CP015196        Location: 335672..540630         Organism: Streptococcus marmotae strain HTS5       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4H00_RS11765 () 332490..332633 - 144 Protein_316 ISL3 family transposase -
A4H00_RS01675 () 332809..333150 - 342 WP_067086510.1 metal-sulfur cluster assembly factor -
A4H00_RS01680 () 333299..333652 - 354 WP_067086512.1 30S ribosome-binding factor RbfA -
A4H00_RS01685 () 334029..336758 - 2730 WP_067091375.1 translation initiation factor IF-2 -
A4H00_RS01690 () 336776..337114 - 339 WP_067086515.1 YlxQ-related RNA-binding protein -
A4H00_RS01695 () 337071..337367 - 297 WP_067086518.1 YlxR family protein -
A4H00_RS01700 () 337386..338534 - 1149 WP_067086521.1 transcription termination/antitermination protein NusA -
A4H00_RS01705 () 338567..339037 - 471 WP_067086524.1 hypothetical protein VF
A4H00_RS01710 () 339628..340389 + 762 WP_067086527.1 hypothetical protein -
A4H00_RS01715 () 340419..341060 + 642 WP_067086529.1 hypothetical protein -
A4H00_RS01720 () 341075..341971 + 897 WP_067086531.1 hypothetical protein -
A4H00_RS11980 () 342108..342560 - 453 WP_067086533.1 hypothetical protein -
A4H00_RS01730 () 342902..344035 - 1134 WP_067086536.1 hypothetical protein VF
A4H00_RS01735 () 344032..344565 - 534 WP_082815569.1 GNAT family N-acetyltransferase -
A4H00_RS01740 () 344552..345001 - 450 WP_099092182.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
A4H00_RS01745 () 345094..346554 - 1461 WP_067086542.1 NCS2 family permease -
A4H00_RS01750 () 346805..347620 + 816 WP_067086546.1 Cof-type HAD-IIB family hydrolase -
A4H00_RS01755 () 348050..349042 + 993 WP_067086547.1 PTS sugar transporter subunit IIB -
A4H00_RS01760 () 349229..350029 + 801 WP_067091384.1 PTS mannose/fructose/sorbose transporter subunit IIC -
A4H00_RS01765 () 350045..350956 + 912 WP_067086550.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
A4H00_RS01770 () 351108..351479 + 372 WP_067086554.1 DUF956 family protein -
A4H00_RS01775 () 351690..352967 + 1278 WP_067086556.1 serine--tRNA ligase -
A4H00_RS01780 () 353292..354548 + 1257 WP_067085967.1 ISL3 family transposase ISSsu6 Transposase
A4H00_RS01785 () 355024..355638 + 615 WP_067086559.1 hypothetical protein -
A4H00_RS01790 () 355875..356642 - 768 WP_067086562.1 acetyl-CoA carboxylase carboxyl transferase subunit alpha -
A4H00_RS01795 () 356639..357505 - 867 WP_067086565.1 acetyl-CoA carboxylase, carboxyltransferase subunit beta -
A4H00_RS01800 () 357674..359044 - 1371 WP_067086567.1 acetyl-CoA carboxylase biotin carboxylase subunit -
A4H00_RS01805 () 359218..359640 - 423 WP_067086570.1 hypothetical protein VF
A4H00_RS01810 () 359637..360104 - 468 WP_067086573.1 acetyl-CoA carboxylase biotin carboxyl carrier protein -
A4H00_RS01815 () 360105..361337 - 1233 WP_067086577.1 hypothetical protein VF
A4H00_RS01820 () 361349..362083 - 735 WP_067086581.1 hypothetical protein VF
A4H00_RS01825 () 362087..363010 - 924 WP_067086584.1 hypothetical protein VF
A4H00_RS01830 () 363012..363977 - 966 WP_067086586.1 enoyl-[acyl-carrier-protein] reductase FabK -
A4H00_RS01835 () 364290..364514 - 225 WP_067086589.1 hypothetical protein VF
A4H00_RS01840 () 364575..365552 - 978 WP_067086592.1 ketoacyl-ACP synthase III -
A4H00_RS01845 () 365549..365983 - 435 WP_067086595.1 MarR family transcriptional regulator -
A4H00_RS01850 () 366564..367913 + 1350 WP_067086598.1 aspartate kinase -
A4H00_RS01855 () 367983..368981 - 999 WP_067086601.1 tagatose-bisphosphate aldolase -
A4H00_RS01860 () 369061..370212 - 1152 WP_067086604.1 N-acetylglucosamine-6-phosphate deacetylase -
A4H00_RS01865 () 370489..371592 - 1104 WP_067086607.1 alanine racemase -
A4H00_RS01870 () 371573..371944 - 372 WP_067086610.1 holo-ACP synthase -
A4H00_RS01875 () 372016..374250 - 2235 WP_167541350.1 preprotein translocase subunit SecA -
A4H00_RS11985 () 374223..374546 - 324 WP_167541351.1 preprotein translocase SecA -
A4H00_RS01880 () 374688..375632 - 945 WP_067086612.1 mannose-6-phosphate isomerase, class I -
A4H00_RS01885 () 375789..376670 - 882 WP_067086615.1 ROK family protein -
A4H00_RS01890 () 376760..378661 - 1902 WP_067086617.1 sucrose-specific PTS transporter subunit IIBC -
A4H00_RS01895 () 378882..380336 + 1455 WP_067086620.1 sucrose-6-phosphate hydrolase -
A4H00_RS01900 () 380317..381279 + 963 WP_067086622.1 LacI family DNA-binding transcriptional regulator -
A4H00_RS01905 () 381343..381774 - 432 WP_067086625.1 transcription antitermination factor NusB -
A4H00_RS01910 () 381764..382156 - 393 WP_067086628.1 Asp23/Gls24 family envelope stress response protein -
A4H00_RS01915 () 382184..382744 - 561 WP_067086631.1 elongation factor P -
A4H00_RS01920 () 382808..383869 - 1062 WP_067086634.1 Xaa-Pro peptidase family protein -
A4H00_RS01930 () 385109..385385 - 277 Protein_368 hypothetical protein -
A4H00_RS01935 () 385454..388288 - 2835 WP_067086639.1 excinuclease ABC subunit UvrA -
A4H00_RS01940 () 388413..389357 + 945 WP_067086643.1 magnesium transporter CorA family protein -
A4H00_RS01945 () 389376..390029 + 654 WP_067086645.1 DUF1129 family protein -
A4H00_RS01950 () 390116..391159 - 1044 WP_067086648.1 glycerate kinase -
A4H00_RS01955 () 391723..392040 - 318 WP_067086651.1 hypothetical protein -
A4H00_RS01960 () 392044..392325 - 282 WP_067086653.1 hypothetical protein -
A4H00_RS01965 () 392329..393129 - 801 WP_067086656.1 hypothetical protein -
A4H00_RS01975 () 393227..394332 + 1106 WP_099092148.1 IS3 family transposase IS199 Transposase
A4H00_RS01980 () 394374..394616 - 243 WP_067086659.1 hypothetical protein -
A4H00_RS01985 () 394613..395356 - 744 WP_067086661.1 hypothetical protein -
A4H00_RS01990 () 395499..395831 + 333 WP_067086664.1 helix-turn-helix domain-containing protein -
A4H00_RS11775 () 396004..396144 + 141 WP_157770969.1 hypothetical protein -
A4H00_RS01995 () 396141..396479 + 339 WP_067086667.1 hypothetical protein -
A4H00_RS02000 () 396694..397575 + 882 WP_157770970.1 DUF87 domain-containing protein -
A4H00_RS02005 () 397857..399074 + 1218 WP_067086671.1 hypothetical protein -
A4H00_RS02010 () 399043..399309 + 267 WP_067086673.1 helix-turn-helix domain-containing protein -
A4H00_RS11640 () 399378..400612 + 1235 Protein_385 hypothetical protein ; Integrase Integrase
A4H00_RS02020 () 400682..401074 - 393 WP_067086676.1 30S ribosomal protein S9 -
A4H00_RS02025 () 401094..401540 - 447 WP_067086679.1 50S ribosomal protein L13 -
A4H00_RS11365 () 401828..401926 + 99 WP_082815571.1 helix-turn-helix domain-containing protein -
A4H00_RS02030 () 401889..402137 + 249 Protein_389 IS30 family transposase ISSmi3 Transposase
A4H00_RS11370 () 402518..402760 + 243 Protein_390 helix-turn-helix domain-containing protein -
A4H00_RS02035 () 402942..404558 - 1617 WP_067086685.1 ABC transporter ATP-binding protein/permease -
A4H00_RS02040 () 404797..405360 - 564 WP_067091388.1 TIGR01440 family protein -
A4H00_RS02045 () 405364..405834 - 471 WP_067086688.1 ECF transporter S component -
A4H00_RS02050 () 405824..406585 - 762 WP_067086691.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
A4H00_RS02055 () 406575..407324 - 750 WP_067086693.1 tRNA pseudouridine(38-40) synthase TruA -
A4H00_RS02060 () 407470..407919 + 450 WP_067086696.1 transcriptional repressor -
A4H00_RS02065 () 407968..408276 - 309 WP_067086698.1 hypothetical protein -
A4H00_RS02075 () 409101..409766 - 666 WP_067086704.1 amino acid ABC transporter permease -
A4H00_RS02080 () 409859..410737 - 879 WP_067086708.1 transporter substrate-binding domain-containing protein -
A4H00_RS02085 () 410845..412299 - 1455 WP_067086710.1 amidase -
A4H00_RS02090 () 412987..413157 + 171 Protein_401 helix-turn-helix transcriptional regulator -
A4H00_RS11375 () 413301..413489 + 189 Protein_402 IS30 family transposase -
A4H00_RS02095 () 413619..413879 - 261 WP_067086715.1 hypothetical protein -
A4H00_RS02100 () 413898..414266 - 369 WP_067086718.1 hypothetical protein -
A4H00_RS02110 () 415510..416640 - 1131 WP_067086723.1 molecular chaperone DnaJ -
A4H00_RS02115 () 417311..419134 - 1824 WP_067086726.1 molecular chaperone DnaK -
A4H00_RS02120 () 419496..419870 - 375 WP_082815573.1 nucleotide exchange factor GrpE -
A4H00_RS02125 () 419871..420854 - 984 WP_067086728.1 heat-inducible transcriptional repressor HrcA -
A4H00_RS02130 () 421040..421240 - 201 WP_067086731.1 hypothetical protein -
A4H00_RS02135 () 421237..421770 - 534 WP_067086734.1 DUF2812 domain-containing protein -
A4H00_RS02140 () 421902..422318 - 417 WP_067086737.1 DUF2812 domain-containing protein -
A4H00_RS02145 () 422299..422631 - 333 WP_067086740.1 PadR family transcriptional regulator -
A4H00_RS02150 () 422800..423495 - 696 WP_067086742.1 phosphoglycerate mutase family protein -
A4H00_RS02155 () 423568..424904 - 1337 Protein_414 PFL family protein -
A4H00_RS02160 () 424916..425182 - 267 WP_067086745.1 ACT domain-containing protein -
A4H00_RS02165 () 425206..425472 - 267 WP_067086748.1 hypothetical protein -
A4H00_RS02170 () 425662..426696 - 1035 WP_067086751.1 dihydrodipicolinate reductase -
A4H00_RS02175 () 426787..427623 + 837 WP_067086753.1 helix-turn-helix domain-containing protein -
A4H00_RS02180 () 427822..428913 - 1092 WP_067086756.1 type 2 isopentenyl-diphosphate Delta-isomerase -
A4H00_RS02185 () 428923..429999 - 1077 WP_067086759.1 phosphomevalonate kinase -
A4H00_RS02190 () 429992..431026 - 1035 WP_067086761.1 diphosphomevalonate decarboxylase -
A4H00_RS02195 () 431019..431954 - 936 WP_067086764.1 mevalonate kinase -
A4H00_RS02200 () 432115..434370 + 2256 WP_067086767.1 bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB -
A4H00_RS02205 () 434455..435321 + 867 WP_067086770.1 Hsp33 family molecular chaperone HslO -
A4H00_RS02210 () 435314..436306 + 993 WP_067086772.1 tRNA dihydrouridine synthase DusB -
A4H00_RS02215 () 436508..438958 - 2451 WP_067086775.1 hypothetical protein VF
A4H00_RS02220 () 438960..439418 - 459 WP_067086778.1 CtsR family transcriptional regulator -
A4H00_RS02225 () 439697..440074 - 378 WP_067086781.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin Detail
A4H00_RS02230 () 440109..440300 - 192 WP_067086783.1 type II toxin-antitoxin system HicA family toxin Toxin Detail
A4H00_RS02235 () 440485..440898 - 414 WP_067086786.1 hypothetical protein -
A4H00_RS02240 () 440891..441202 - 312 WP_067086789.1 hypothetical protein -
A4H00_RS02245 () 441337..441690 - 354 WP_067086791.1 replication protein -
A4H00_RS02250 () 441745..442365 - 621 WP_067086793.1 hypothetical protein -
A4H00_RS02255 () 442406..442762 - 357 WP_067086796.1 minor capsid protein -
A4H00_RS02260 () 442849..443016 - 168 WP_082815654.1 DUF2292 domain-containing protein -
A4H00_RS02265 () 443025..443276 - 252 WP_067086800.1 hypothetical protein -
A4H00_RS02270 () 443273..443524 - 252 WP_067086803.1 hypothetical protein -
A4H00_RS02275 () 443831..444904 - 1074 WP_099092180.1 virulence-associated E family protein -
A4H00_RS02280 () 445248..445763 - 516 WP_067085974.1 hypothetical protein -
A4H00_RS02285 () 445756..446037 - 282 WP_067085977.1 hypothetical protein -
A4H00_RS02290 () 446047..446265 - 219 WP_067085980.1 hypothetical protein -
A4H00_RS02300 () 446440..446679 - 240 WP_067085985.1 hypothetical protein -
A4H00_RS11780 () 446935..447099 - 165 WP_157770961.1 hypothetical protein -
A4H00_RS02305 () 447092..447556 - 465 WP_067085987.1 hypothetical protein -
A4H00_RS02310 () 447616..447816 - 201 WP_067085989.1 helix-turn-helix transcriptional regulator -
A4H00_RS02315 () 448081..448737 + 657 WP_167541365.1 XRE family transcriptional regulator -
A4H00_RS02320 () 448780..449601 + 822 WP_067085994.1 EbhA -
A4H00_RS02325 () 449644..450201 + 558 WP_067085997.1 GTP pyrophosphokinase -
A4H00_RS02330 () 450364..451032 + 669 WP_067086806.1 hypothetical protein VF
A4H00_RS11785 () 451712..451804 - 93 WP_157770972.1 type I toxin-antitoxin system Fst family toxin -
A4H00_RS02335 () 452036..453202 + 1167 WP_067086808.1 hypothetical protein ; Integrase Integrase
A4H00_RS02340 () 453468..453818 + 351 WP_067086811.1 conjugal transfer protein TraF -
A4H00_RS02345 () 453820..454536 + 717 WP_067086814.1 hypothetical protein -
A4H00_RS02350 () 454580..455620 - 1041 WP_067086816.1 elongation factor Ts -
A4H00_RS02355 () 455703..456485 - 783 WP_067086819.1 30S ribosomal protein S2 -
A4H00_RS02360 () 456778..457731 + 954 WP_067086822.1 IS30 family transposase ISStin9 Transposase
A4H00_RS02365 () 458174..459037 - 864 WP_067086824.1 DegV family protein -
A4H00_RS02370 () 459068..459805 - 738 WP_067086825.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
A4H00_RS02375 () 460028..460876 - 849 WP_082815574.1 DUF4300 family protein -
A4H00_RS02380 () 461090..461803 - 714 WP_067086827.1 DUF4767 domain-containing protein -
A4H00_RS02385 () 461884..462849 + 966 WP_067086829.1 aromatic acid exporter family protein -
A4H00_RS02390 () 462909..464041 - 1133 Protein_462 hypothetical protein VF
A4H00_RS02400 () 464335..465273 - 939 WP_067086832.1 helix-turn-helix domain-containing protein -
A4H00_RS02405 () 465282..465662 - 381 WP_067086835.1 Mini-ribonuclease 3 -
A4H00_RS02410 () 465655..466998 - 1344 WP_067086837.1 cysteine--tRNA ligase -
A4H00_RS11790 () 467111..467284 - 174 WP_157770973.1 hypothetical protein -
A4H00_RS02415 () 467274..468047 - 774 WP_067086840.1 nucleoside phosphorylase -
A4H00_RS02420 () 468069..468653 - 585 WP_067086843.1 serine O-acetyltransferase -
A4H00_RS02425 () 468711..470921 - 2211 WP_067086845.1 polyribonucleotide nucleotidyltransferase -
A4H00_RS02430 () 471452..471721 - 270 WP_067086848.1 30S ribosomal protein S15 -
A4H00_RS02435 () 471843..473117 - 1275 WP_067086850.1 NCS2 family nucleobase:cation symporter -
A4H00_RS02440 () 473356..475779 - 2424 WP_067086853.1 hypothetical protein VF
A4H00_RS02445 () 475776..476981 - 1206 WP_067086856.1 hypothetical protein -
A4H00_RS02450 () 476994..477863 - 870 WP_067086859.1 hypothetical protein VF
A4H00_RS02455 () 477856..478725 - 870 WP_067086862.1 hypothetical protein VF
A4H00_RS02460 () 478712..479914 - 1203 WP_067086864.1 hypothetical protein VF
A4H00_RS02465 () 480047..481798 - 1752 WP_067086867.1 hypothetical protein VF
A4H00_RS02470 () 482203..482928 - 726 WP_067086870.1 rRNA pseudouridine synthase -
A4H00_RS02475 () 483434..484048 + 615 WP_067086873.1 peptide deformylase -
A4H00_RS02480 () 484685..485156 - 472 Protein_480 IS200-IS605 family transposase ISSpn6 Transposase
A4H00_RS02485 () 485293..485703 + 411 WP_082815576.1 IS91 family transposase ISShvi3 Transposase
A4H00_RS02490 () 485909..486829 + 921 WP_067086879.1 cysteine synthase A -
A4H00_RS02495 () 486985..487350 - 366 WP_067086881.1 S1 RNA-binding domain-containing protein -
A4H00_RS11990 () 487352..487891 - 540 WP_067086884.1 hypothetical protein VF
A4H00_RS02505 () 487816..488754 - 939 WP_067086887.1 Cof-type HAD-IIB family hydrolase -
A4H00_RS02510 () 488784..489428 - 645 WP_067086890.1 hypothetical protein VF
A4H00_RS02515 () 489397..490416 - 1020 WP_067091396.1 sensor histidine kinase -
A4H00_RS02520 () 490416..491111 - 696 WP_067086893.1 cell wall-active antibiotics response protein -
A4H00_RS02525 () 491485..493464 - 1980 WP_067086895.1 hypothetical protein VF
A4H00_RS02530 () 493464..494201 - 738 WP_067086898.1 hypothetical protein VF
A4H00_RS02535 () 494219..495529 - 1311 WP_067086901.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
A4H00_RS02540 () 495519..496466 - 948 WP_067086903.1 hypothetical protein VF
A4H00_RS02545 () 496645..499023 - 2379 WP_067086906.1 primosomal protein N' -
A4H00_RS02550 () 499106..499420 - 315 WP_067086908.1 DNA-directed RNA polymerase subunit omega -
A4H00_RS02555 () 499437..500057 - 621 WP_067086910.1 guanylate kinase -
A4H00_RS02560 () 500186..501799 - 1614 WP_067086913.1 ribonuclease Y -
A4H00_RS02565 () 501928..502410 + 483 WP_067086916.1 hypothetical protein VF
A4H00_RS02570 () 502517..506632 - 4116 WP_067086919.1 hypothetical protein VF
A4H00_RS02575 () 506648..507217 - 570 WP_067086921.1 hypothetical protein VF
A4H00_RS02580 () 507396..508769 - 1374 WP_067086924.1 hypothetical protein -
A4H00_RS02585 () 508778..509935 - 1158 WP_067086926.1 class I SAM-dependent RNA methyltransferase -
A4H00_RS02595 () 510375..510707 - 333 WP_067086929.1 cell division regulator GpsB -
A4H00_RS02600 () 510779..511312 - 534 WP_067091401.1 DUF1273 domain-containing protein -
A4H00_RS02605 () 511384..512004 + 621 WP_067086932.1 Holliday junction resolvase RecU -
A4H00_RS02610 () 511973..514138 + 2166 WP_099092151.1 penicillin-binding protein PBP1A -
A4H00_RS02615 () 514344..515057 + 714 WP_067086934.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
A4H00_RS02620 () 515199..516035 - 837 WP_067086937.1 energy-coupling factor transporter transmembrane protein EcfT -
A4H00_RS02625 () 516039..517709 - 1671 WP_067086940.1 hypothetical protein VF
A4H00_RS02630 () 518381..519592 - 1212 WP_067086943.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
A4H00_RS02635 () 519613..520815 - 1203 WP_067086946.1 MFS transporter -
A4H00_RS02640 () 520829..521182 - 354 WP_067086948.1 Rid family detoxifying hydrolase -
A4H00_RS02645 () 521424..522074 - 651 WP_067086951.1 PAS domain-containing protein -
A4H00_RS02650 () 522304..523290 - 987 WP_067086954.1 rhodanese-related sulfurtransferase -
A4H00_RS02655 () 523450..523995 - 546 WP_067086957.1 ECF-type riboflavin transporter substrate-binding protein -
A4H00_RS02660 () 524013..524861 - 849 WP_067086959.1 S-adenosyl-l-methionine hydroxide adenosyltransferase family protein -
A4H00_RS02665 () 525178..526167 - 990 WP_067086962.1 hypothetical protein VF
A4H00_RS02670 () 526597..528354 - 1758 WP_067086965.1 dihydrolipoyl dehydrogenase -
A4H00_RS02675 () 528546..529934 - 1389 WP_067086967.1 dihydrolipoamide acetyltransferase -
A4H00_RS02680 () 530024..531019 - 996 WP_067086971.1 alpha-ketoacid dehydrogenase subunit beta -
A4H00_RS02685 () 531111..532079 - 969 WP_067086974.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
A4H00_RS02690 () 532311..532973 + 663 WP_067086976.1 trimeric intracellular cation channel family protein -
A4H00_RS02695 () 533248..534696 - 1449 WP_067086979.1 hypothetical protein VF
A4H00_RS02700 () 534660..535319 - 660 WP_067086981.1 energy-coupling factor transporter transmembrane protein EcfT -
A4H00_RS02705 () 535316..535909 - 594 WP_067086984.1 MptD family putative ECF transporter S component -
A4H00_RS02710 () 536027..537694 - 1668 WP_067086987.1 ABC transporter ATP-binding protein/permease -
A4H00_RS02715 () 537687..539444 - 1758 WP_067086989.1 ABC transporter ATP-binding protein/permease -
A4H00_RS02720 () 539597..540748 + 1152 WP_067086991.1 hypothetical protein -
A4H00_RS02725 () 541240..541479 - 240 WP_002939250.1 30S ribosomal protein S18 -
A4H00_RS02730 () 541514..542008 - 495 WP_067086994.1 single-stranded DNA-binding protein -
A4H00_RS02735 () 542020..542310 - 291 WP_067086996.1 30S ribosomal protein S6 -
A4H00_RS02740 () 542478..543431 - 954 WP_067086998.1 IS30 family transposase -
A4H00_RS02745 () 543554..544918 - 1365 WP_067087001.1 glycoside hydrolase family 32 protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance