MGE detailed information
MGE type: Conjugative plasmid MGE length: 163420 bp
Accession: NZ_CP012572 Location: 1..163420 Organism: Klebsiella pneumoniae strain UCLAOXA232KP Replicon: plasmid pUCLAOXA232-6.X
Accession: NZ_CP012572 Location: 1..163420 Organism: Klebsiella pneumoniae strain UCLAOXA232KP Replicon: plasmid pUCLAOXA232-6.X
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AM278_RS29550 () | 1611..2777 | + | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
| AM278_RS29555 () | 2777..3748 | + | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| AM278_RS29570 () | 5057..6255 | + | 1199 | Protein_3 | IS200-IS605 family transposase IS609 | Transposase |
| AM278_RS29575 () | 6278..6493 | - | 216 | Protein_4 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| AM278_RS29580 () | 6572..7843 | - | 1272 | WP_014386156.1 | Y-family DNA polymerase | - |
| AM278_RS29585 () | 7843..8268 | - | 426 | WP_004182047.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| AM278_RS29590 () | 8483..8713 | + | 231 | WP_004118481.1 | hypothetical protein | - |
| AM278_RS29595 () | 9234..9659 | + | 426 | WP_004118478.1 | antirestriction protein | - |
| AM278_RS29600 () | 9896..10150 | + | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| AM278_RS29605 () | 10185..10502 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| AM278_RS29620 () | 11286..11513 | + | 228 | WP_004152790.1 | hypothetical protein | - |
| AM278_RS29625 () | 11605..11835 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| AM278_RS29630 () | 11887..13242 | + | 1356 | WP_071854291.1 | DUF3560 domain-containing protein | - |
| AM278_RS29635 () | 13290..13853 | + | 564 | WP_004152756.1 | methyltransferase | - |
| AM278_RS29655 () | 14684..15226 | + | 543 | WP_071854301.1 | single-stranded DNA-binding protein | - |
| AM278_RS29660 () | 15275..15523 | + | 249 | WP_014386159.1 | DUF905 domain-containing protein | - |
| AM278_RS29665 () | 15593..17650 | + | 2058 | WP_014386160.1 | ParB/RepB/Spo0J family partition protein | - |
| AM278_RS29670 () | 17695..18126 | + | 432 | WP_014386161.1 | conjugation system SOS inhibitor PsiB | - |
| AM278_RS29675 () | 18123..18851 | + | 729 | WP_014386162.1 | plasmid SOS inhibition protein A | - |
| AM278_RS29680 () | 18848..19174 | + | 327 | WP_004152639.1 | hypothetical protein | - |
| AM278_RS29685 () | 19230..19604 | + | 375 | WP_032408891.1 | hypothetical protein | - |
| AM278_RS29690 () | 19814..20839 | + | 1026 | WP_015632466.1 | IS110 family transposase ISAve1 | Transposase |
| AM278_RS29695 () | 21158..22126 | - | 969 | WP_074422984.1 | IS5 family transposase IS903B | Transposase |
| AM278_RS29700 () | 22449..22865 | - | 417 | WP_014386165.1 | PIN domain-containing protein | Toxin Detail |
| AM278_RS29705 () | 22862..23092 | - | 231 | WP_032408893.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| AM278_RS29710 () | 23412..23846 | + | 435 | WP_000103648.1 | RidA family protein | - |
| AM278_RS29715 () | 23851..24525 | + | 675 | WP_014386166.1 | DUF1028 domain-containing protein | - |
| AM278_RS29720 () | 24541..25698 | + | 1158 | WP_032408895.1 | acetylornithine deacetylase | - |
| AM278_RS29725 () | 25869..27017 | + | 1149 | WP_014386168.1 | Spermidine/putrescine import ATP-binding protein PotA | VF |
| AM278_RS29730 () | 27024..28019 | + | 996 | WP_000611945.1 | Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC | VF |
| AM278_RS29735 () | 28016..28630 | + | 615 | WP_014386169.1 | glutathione S-transferase N-terminal domain-containing protein | - |
| AM278_RS29740 () | 28643..29092 | + | 450 | WP_000082700.1 | 3-dehydroquinate dehydratase | - |
| AM278_RS29745 () | 29089..30018 | + | 930 | WP_014386170.1 | glyoxylate/hydroxypyruvate reductase A | - |
| AM278_RS29750 () | 30030..30992 | - | 963 | WP_000952529.1 | LysR family transcriptional regulator | - |
| AM278_RS29760 () | 31331..32362 | + | 1032 | WP_001327073.1 | ABC transporter substrate-binding protein | - |
| AM278_RS29765 () | 32428..33282 | + | 855 | WP_000197183.1 | ABC transporter permease | - |
| AM278_RS29770 () | 33284..34102 | + | 819 | WP_014386171.1 | ABC transporter permease | - |
| AM278_RS29775 () | 34233..35483 | + | 1251 | WP_014386172.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| AM278_RS29780 () | 35556..36719 | + | 1164 | WP_001471748.1 | alpha-hydroxy-acid oxidizing protein | - |
| AM278_RS29790 () | 37160..37871 | - | 712 | Protein_40 | IS481 family transposase ISKpn28 | Transposase |
| AM278_RS29800 () | 38102..38194 | + | 93 | Protein_41 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| AM278_RS29805 () | 38358..39746 | - | 1389 | WP_014386175.1 | sugar porter family MFS transporter | - |
| AM278_RS29810 () | 39778..40689 | - | 912 | WP_014386176.1 | ROK family protein | - |
| AM278_RS29815 () | 40686..41699 | - | 1014 | WP_014386177.1 | SIS domain-containing protein | - |
| AM278_RS29820 () | 41927..42682 | + | 756 | WP_032408898.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| AM278_RS29825 () | 42944..43384 | + | 441 | WP_014386179.1 | IS66 family transposase ISKox1 | Transposase |
| AM278_RS29830 () | 43381..43731 | + | 351 | WP_014386180.1 | IS66 family transposase ISKox1 | Transposase |
| AM278_RS29840 () | 43762..45354 | + | 1593 | Protein_48 | IS66 family transposase ISEcl6 | Transposase |
| AM278_RS29845 () | 45551..45802 | + | 252 | WP_032408900.1 | aldo/keto reductase | - |
| AM278_RS29850 () | 46243..46734 | - | 492 | WP_032408901.1 | GNAT family N-acetyltransferase | Toxin Detail |
| AM278_RS29855 () | 46722..46988 | - | 267 | WP_014386183.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| AM278_RS29860 () | 47185..47343 | + | 159 | WP_014386184.1 | type I toxin-antitoxin system Hok family toxin | - |
| AM278_RS29865 () | 47587..48072 | - | 486 | WP_014386185.1 | hypothetical protein | - |
| AM278_RS29870 () | 48262..48534 | + | 273 | WP_032408902.1 | hypothetical protein | - |
| AM278_RS29875 () | 48531..48881 | + | 351 | WP_014386186.1 | hypothetical protein | - |
| AM278_RS29890 () | 49518..49844 | + | 327 | WP_014386187.1 | hypothetical protein | - |
| AM278_RS29895 () | 49906..50118 | + | 213 | WP_014386188.1 | hypothetical protein | - |
| AM278_RS29900 () | 50129..50353 | + | 225 | WP_014386189.1 | hypothetical protein | - |
| AM278_RS29905 () | 50434..50754 | + | 321 | WP_014386190.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| AM278_RS29910 () | 50744..51022 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| AM278_RS29915 () | 51023..51436 | + | 414 | WP_013023817.1 | helix-turn-helix domain-containing protein | - |
| AM278_RS29935 () | 52269..53089 | + | 821 | Protein_62 | DUF945 domain-containing protein | - |
| AM278_RS29940 () | 53480..53965 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| AM278_RS29945 () | 54356..54772 | + | 417 | WP_072145360.1 | relaxosome protein TraM | - |
| AM278_RS29950 () | 54971..55690 | + | 720 | WP_162899473.1 | conjugal transfer protein TrbJ | - |
| AM278_RS29955 () | 55823..56026 | + | 204 | WP_171486139.1 | TraY domain-containing protein | - |
| AM278_RS29960 () | 56091..56459 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| AM278_RS29965 () | 56473..56778 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| AM278_RS29970 () | 56798..57364 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| AM278_RS29975 () | 57351..58091 | + | 741 | WP_013214019.1 | type-F conjugative transfer system secretin TraK | - |
| AM278_RS29980 () | 58091..59515 | + | 1425 | WP_032426793.1 | conjugal transfer protein TraB | - |
| AM278_RS29985 () | 59629..60213 | + | 585 | WP_004161368.1 | type IV conjugative transfer system lipoprotein TraV | - |
| AM278_RS29990 () | 60536..60754 | + | 219 | WP_004195468.1 | hypothetical protein | - |
| AM278_RS29995 () | 60755..61066 | + | 312 | WP_013214022.1 | hypothetical protein | - |
| AM278_RS30000 () | 61133..61537 | + | 405 | WP_004197817.1 | hypothetical protein | - |
| AM278_RS30015 () | 61914..62312 | + | 399 | WP_014343490.1 | hypothetical protein | - |
| AM278_RS30020 () | 62384..65023 | + | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| AM278_RS30025 () | 65023..65412 | + | 390 | WP_013214025.1 | type-F conjugative transfer system protein TrbI | - |
| AM278_RS30030 () | 65412..66047 | + | 636 | WP_013214026.1 | type-F conjugative transfer system protein TraW | - |
| AM278_RS30035 () | 66082..66483 | + | 402 | WP_004194979.1 | hypothetical protein | - |
| AM278_RS30040 () | 66480..67469 | + | 990 | WP_013214027.1 | conjugal transfer pilus assembly protein TraU | - |
| AM278_RS30045 () | 67482..68120 | + | 639 | WP_004193871.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| AM278_RS30050 () | 68179..70134 | + | 1956 | WP_014343489.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| AM278_RS30055 () | 70166..70420 | + | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| AM278_RS30060 () | 70398..70646 | + | 249 | WP_013214029.1 | hypothetical protein | - |
| AM278_RS30065 () | 70659..70985 | + | 327 | WP_013214030.1 | hypothetical protein | - |
| AM278_RS30070 () | 71006..71758 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| AM278_RS30075 () | 71769..72008 | + | 240 | WP_032440623.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| AM278_RS30080 () | 71980..72537 | + | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| AM278_RS30085 () | 72583..73026 | + | 444 | WP_013214032.1 | F-type conjugal transfer protein TrbF | - |
| AM278_RS30090 () | 73004..74383 | + | 1380 | WP_072157884.1 | conjugal transfer protein TraH | - |
| AM278_RS30095 () | 74383..77205 | + | 2823 | WP_013214034.1 | conjugal transfer mating pair stabilization protein TraG | - |
| AM278_RS30100 () | 77228..77830 | + | 603 | WP_013214035.1 | conjugal transfer protein TraS | - |
| AM278_RS30105 () | 78081..78812 | + | 732 | WP_013214036.1 | complement resistance protein TraT | - |
| AM278_RS32060 () | 79005..79694 | + | 690 | WP_014343485.1 | hypothetical protein | - |
| AM278_RS30115 () | 79821..82130 | + | 2310 | Protein_96 | type IV conjugative transfer system coupling protein TraD | - |
| AM278_RS30120 () | 82130..87388 | + | 5259 | WP_071854302.1 | Multifunctional conjugation protein TraI | Relaxase |
| AM278_RS30125 () | 87433..88158 | + | 726 | WP_014386207.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| AM278_RS30130 () | 88230..88823 | + | 594 | WP_004152380.1 | fertility inhibition protein FinO | - |
| AM278_RS30795 () | 89009..89706 | + | 698 | Protein_100 | IS1 family transposase | - |
| AM278_RS30150 () | 90010..91533 | + | 1524 | WP_014386209.1 | type I restriction-modification system subunit M | - |
| AM278_RS30155 () | 91523..92749 | + | 1227 | WP_014386210.1 | restriction endonuclease subunit S | - |
| AM278_RS30160 () | 92746..93429 | + | 684 | WP_014386211.1 | YecA family protein | - |
| AM278_RS30165 () | 93452..95236 | + | 1785 | WP_032408859.1 | cold shock domain-containing protein | - |
| AM278_RS30170 () | 95306..98590 | + | 3285 | WP_040182250.1 | type I restriction endonuclease subunit R | - |
| AM278_RS30175 () | 98587..99342 | + | 756 | WP_009310009.1 | M48 family metallopeptidase | - |
| AM278_RS30180 () | 99429..99614 | + | 186 | Protein_107 | IS1 family transposase IS1A | Transposase |
| AM278_RS31445 () | 99613..99852 | + | 240 | Protein_108 | IS110 family transposase | - |
| AM278_RS30190 () | 99869..100177 | + | 309 | Protein_109 | DDE-type integrase/transposase/recombinase | - |
| AM278_RS30195 () | 100202..101653 | + | 1452 | WP_000443938.1 | DUF262 domain-containing protein | - |
| AM278_RS30200 () | 101646..103688 | + | 2043 | WP_014386214.1 | DUF262 domain-containing HNH endonuclease family protein | - |
| AM278_RS30210 () | 103928..104625 | + | 698 | Protein_112 | IS1 family transposase ISKpn14 | Transposase |
| AM278_RS30220 () | 104993..105472 | + | 480 | WP_064762441.1 | Phospholipase D | VF |
| AM278_RS30225 () | 105792..106070 | + | 279 | WP_004099069.1 | replication regulatory protein RepA | - |
| AM278_RS30235 () | 106286..106363 | + | 78 | WP_014386216.1 | RepA leader peptide Tap | - |
| AM278_RS30240 () | 106356..107213 | + | 858 | WP_004099067.1 | incFII family plasmid replication initiator RepA | - |
| AM278_RS30260 () | 108202..108855 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| AM278_RS30265 () | 108948..109205 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| AM278_RS30270 () | 109138..109539 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| AM278_RS30275 () | 109676..112573 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| AM278_RS30280 () | 112668..112781 | + | 114 | Protein_121 | recombinase family protein | - |
| AM278_RS30285 () | 112843..113547 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| AM278_RS30295 () | 113789..114139 | + | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| AM278_RS30300 () | 114189..114551 | + | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| AM278_RS30305 () | 114569..116320 | + | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| AM278_RS30310 () | 116368..117657 | + | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| AM278_RS30315 () | 117670..118095 | + | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| AM278_RS30320 () | 118128..118664 | - | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| AM278_RS30325 () | 118786..120536 | - | 1751 | Protein_129 | arsenical pump-driving ATPase | - |
| AM278_RS30330 () | 120561..120923 | - | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| AM278_RS30335 () | 120999..121544 | - | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| AM278_RS30340 () | 121553..122266 | - | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| AM278_RS30345 () | 122263..122589 | - | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| AM278_RS30350 () | 122921..123418 | + | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| AM278_RS30355 () | 123468..123977 | - | 510 | WP_031944101.1 | aquaporin | - |
| AM278_RS30810 () | 124039..125659 | + | 1621 | Protein_136 | ISL3 family transposase ISEc38 | Transposase |
| AM278_RS30370 () | 125720..125899 | + | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| AM278_RS30375 () | 126131..126565 | - | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| AM278_RS30380 () | 126782..128182 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| AM278_RS30385 () | 128179..128859 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| AM278_RS30390 () | 128914..129843 | - | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| AM278_RS30395 () | 129848..130228 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| AM278_RS30400 () | 130268..131158 | - | 891 | WP_185157552.1 | copper resistance outer membrane transporter PcoB | - |
| AM278_RS30405 () | 131164..132981 | - | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| AM278_RS30410 () | 133215..133664 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| AM278_RS30415 () | 133953..134690 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| AM278_RS30420 () | 134724..134921 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| AM278_RS30425 () | 134962..137409 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| AM278_RS30430 () | 137536..137976 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| AM278_RS30435 () | 138063..141209 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| AM278_RS30440 () | 141220..142512 | - | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| AM278_RS30445 () | 142626..142979 | - | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| AM278_RS30450 () | 143008..144393 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| AM278_RS30455 () | 144583..145263 | + | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| AM278_RS30460 () | 145256..146731 | + | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| AM278_RS30465 () | 146982..147413 | + | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| AM278_RS30470 () | 147709..148251 | - | 543 | Protein_157 | ISL3 family transposase ISKpn25 | Transposase |
| AM278_RS30475 () | 148267..148751 | - | 485 | Protein_158 | IS1 family transposase IS1X2 | Transposase |
| AM278_RS30485 () | 148842..150049 | + | 1208 | WP_085955172.1 | IS3 family transposase ISEcl1 | Transposase |
| AM278_RS30500 () | 150240..150937 | + | 698 | Protein_160 | IS1 family transposase IS1X2 | Transposase |
| AM278_RS30505 () | 151089..153086 | + | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| AM278_RS30510 () | 153149..154426 | + | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| AM278_RS30515 () | 155409..156845 | - | 1437 | WP_080895248.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| AM278_RS30520 () | 157465..157722 | + | 258 | WP_004197688.1 | hypothetical protein | - |
| AM278_RS30525 () | 158395..159363 | - | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| AM278_RS30530 () | 159383..159694 | + | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| AM278_RS30535 () | 159721..160668 | - | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| AM278_RS30545 () | 161812..162552 | + | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|