MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 200151 bp
Accession: NZ_CP012461        Location: 1..200151         Organism: Enterococcus faecium strain ISMMS_VRE_7       Replicon: plasmid ISMMS_VRE7_p1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL020_RS13910 () 917..1849 + 933 WP_002339140.1 FAD:protein FMN transferase -
AL020_RS13915 () 1892..2503 + 612 WP_002339141.1 NAD(P)H-dependent oxidoreductase -
AL020_RS13920 () 2523..3743 + 1221 WP_002339142.1 PAS domain-containing protein -
AL020_RS13925 () 3801..4481 - 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
AL020_RS16930 () 4556..4834 + 279 Protein_5 site-specific recombinase -
AL020_RS13930 () 4977..5198 + 222 WP_002331328.1 helix-turn-helix transcriptional regulator -
AL020_RS13935 () 5214..6056 + 843 WP_002342384.1 hypothetical protein -
AL020_RS13940 () 6119..7921 + 1803 WP_002342383.1 3'-5' exoribonuclease -
AL020_RS13945 () 7980..8888 - 909 WP_016171164.1 IS982 family transposase ISEfm1 Transposase
AL020_RS17415 () 8999..9270 + 272 Protein_10 HAD-IA family hydrolase -
AL020_RS13955 () 9809..10009 + 201 Protein_11 hypothetical protein -
AL020_RS13960 () 10496..10675 + 180 WP_002340501.1 IS21 family transposase ISAar36 Transposase
AL020_RS13965 () 10721..11326 - 606 WP_002313084.1 Tn3 family transposase TnpR_ISPa40 Transposase
AL020_RS13970 () 11508..11843 + 336 Protein_14 Tn3 family transposase TnpA_ISXc4 Transposase
AL020_RS17420 () 12008..12235 + 228 Protein_15 IS110 family transposase -
AL020_RS13975 () 12361..13332 + 972 WP_016171162.1 LacI family DNA-binding transcriptional regulator -
AL020_RS13980 () 13472..14785 + 1314 WP_016171161.1 sugar ABC transporter substrate-binding protein -
AL020_RS13985 () 14828..15694 + 867 WP_002348858.1 sugar ABC transporter permease -
AL020_RS13990 () 15691..16539 + 849 WP_002313079.1 carbohydrate ABC transporter permease -
AL020_RS13995 () 16553..18025 + 1473 WP_002322556.1 glycoside hydrolase family 32 protein -
AL020_RS14000 () 18042..18914 + 873 WP_016171159.1 ROK family protein -
AL020_RS16945 () 19150..20532 - 1383 Protein_22 IS3 family transposase ISLca1 Transposase
AL020_RS14015 () 20994..21275 + 282 Protein_23 YfbU family protein -
AL020_RS14020 () 21349..22029 + 681 Protein_24 IS6 family transposase IS1216V Transposase
AL020_RS14025 () 22178..22507 + 330 WP_002292678.1 AbrB family transcriptional regulator -
AL020_RS14030 () 22497..22784 + 288 WP_002313074.1 type II toxin-antitoxin system RelE/ParE family toxin -
AL020_RS14035 () 23070..23927 + 858 WP_002292680.1 AAA family ATPase -
AL020_RS14040 () 23928..24476 + 549 WP_002292681.1 hypothetical protein -
AL020_RS14045 () 24736..25464 + 729 WP_002348804.1 hypothetical protein -
AL020_RS14050 () 25494..26666 + 1173 WP_010782530.1 S8 family serine peptidase -
AL020_RS14055 () 26590..27543 - 954 WP_010782694.1 IS30 family transposase IS1252 Transposase
AL020_RS14060 () 27625..27975 - 351 WP_010782532.1 ribonucleotide-diphosphate reductase subunit beta -
AL020_RS14065 () 28024..28467 - 444 WP_002348760.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
AL020_RS14070 () 28614..29279 + 666 WP_002348761.1 Crp/Fnr family transcriptional regulator -
AL020_RS14075 () 29269..29724 + 456 WP_025480881.1 6,7-dimethyl-8-ribityllumazine synthase -
AL020_RS14080 () 29874..31253 + 1380 WP_002348763.1 M24 family metallopeptidase -
AL020_RS14085 () 31390..32232 + 843 WP_002348764.1 glycosyltransferase family 8 protein -
AL020_RS14090 () 32306..33754 + 1449 Protein_38 type I restriction endonuclease subunit R -
AL020_RS14095 () 33869..35641 + 1773 WP_002348758.1 AAA family ATPase -
AL020_RS14100 () 35616..36908 + 1293 WP_010782535.1 hypothetical protein -
AL020_RS14105 () 37371..38279 - 909 WP_010782529.1 IS982 family transposase ISEfm1 Transposase
AL020_RS14110 () 38646..39944 + 1299 WP_002348634.1 polysaccharide deacetylase family protein -
AL020_RS14115 () 40591..41271 + 681 Protein_43 IS6 family transposase IS1297 Transposase
AL020_RS14125 () 41436..41817 + 382 Protein_44 hypothetical protein -
AL020_RS14130 () 41948..42898 + 951 WP_002303241.1 magnesium transporter CorA family protein -
AL020_RS14135 () 43416..43871 + 456 WP_002303240.1 tyrosine-type recombinase/integrase -
AL020_RS17740 () 44269..44814 + 546 WP_172820227.1 hypothetical protein -
AL020_RS17745 () 44908..45240 + 333 WP_072538890.1 topoisomerase I -
AL020_RS16970 () 45391..46370 - 980 Protein_49 tyrosine-type recombinase/integrase -
AL020_RS14155 () 46375..47142 - 768 WP_002290556.1 DeoR/GlpR family DNA-binding transcription regulator -
AL020_RS14160 () 47632..48057 + 426 WP_002290555.1 galactose-6-phosphate isomerase subunit LacA -
AL020_RS14165 () 48074..48589 + 516 WP_002290554.1 galactose-6-phosphate isomerase subunit LacB -
AL020_RS14170 () 48600..49532 + 933 WP_002290553.1 tagatose-6-phosphate kinase -
AL020_RS14175 () 49535..50515 + 981 WP_002290551.1 tagatose-bisphosphate aldolase -
AL020_RS14180 () 50543..50859 + 317 Protein_55 PTS lactose/cellobiose transporter subunit IIA -
AL020_RS14185 () 50859..52565 + 1707 WP_002290549.1 lactose-specific PTS transporter subunit EIIC -
AL020_RS14190 () 52707..54113 + 1407 WP_002290548.1 6-phospho-beta-galactosidase -
AL020_RS14195 () 54136..54408 + 273 WP_002305107.1 DUF3884 family protein -
AL020_RS14200 () 54429..55328 + 900 WP_002303235.1 aldose 1-epimerase family protein -
AL020_RS14215 () 57042..57605 + 564 Protein_61 IS6 family transposase IS1297 Transposase
AL020_RS14220 () 57611..58027 + 417 WP_002303153.1 hypothetical protein -
AL020_RS14225 () 58133..58396 + 264 WP_002303154.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
AL020_RS14230 () 58396..58668 + 273 WP_002305108.1 Txe/YoeB family addiction module toxin Toxin Detail
AL020_RS14235 () 58745..59074 + 330 WP_002292678.1 AbrB family transcriptional regulator -
AL020_RS14240 () 59064..59351 + 288 WP_002300557.1 type II toxin-antitoxin system RelE/ParE family toxin -
AL020_RS14245 () 59637..60494 + 858 WP_002292680.1 AAA family ATPase -
AL020_RS14250 () 60495..61043 + 549 WP_002292681.1 hypothetical protein -
AL020_RS14255 () 61340..62287 - 948 WP_002303155.1 DNA-binding transcriptional regulator -
AL020_RS14260 () 62475..63662 + 1188 WP_002303156.1 NADP-dependent malic enzyme -
AL020_RS14265 () 63643..64947 + 1305 WP_002303157.1 2-hydroxycarboxylate transporter family protein -
AL020_RS14270 () 64973..65986 + 1014 WP_002303158.1 [citrate (pro-3S)-lyase] ligase -
AL020_RS14275 () 65990..66283 + 294 WP_002303159.1 citrate lyase acyl carrier protein -
AL020_RS14280 () 66288..67193 + 906 WP_002303160.1 citrate (pro-3S)-lyase subunit beta -
AL020_RS14285 () 67186..68745 + 1560 WP_002303161.1 citrate lyase subunit alpha -
AL020_RS14290 () 68742..69299 + 558 WP_002305953.1 citrate lyase holo-[acyl-carrier protein] synthase -
AL020_RS14295 () 69292..70155 + 864 WP_002303163.1 triphosphoribosyl-dephospho-CoA synthase CitG -
AL020_RS14300 () 70389..70798 + 410 Protein_78 IS200-IS605 family transposase ISAac1 Transposase
AL020_RS14305 () 71435..72607 - 1173 WP_002316137.1 IS256 family transposase IS256 Transposase
AL020_RS16985 () 73281..74093 + 813 WP_002307497.1 hypothetical protein -
AL020_RS14315 () 74629..75807 - 1179 WP_002324322.1 IS256 family transposase ISEfm2 Transposase
AL020_RS14320 () 77061..77615 + 555 WP_002301108.1 tyrosine-type recombinase/integrase -
AL020_RS17565 () 77869..78180 + 312 Protein_83 hypothetical protein -
AL020_RS14330 () 78291..79199 + 909 WP_002326839.1 IS982 family transposase ISEfm1 Transposase
AL020_RS14335 () 79269..79748 + 480 WP_002313278.1 hypothetical protein -
AL020_RS14340 () 80052..80267 - 216 Protein_86 IS256 family transposase ISEf1 Transposase
AL020_RS17615 () 81810..82352 + 543 WP_002298088.1 hypothetical protein -
AL020_RS14360 () 82508..82957 + 450 WP_002330699.1 TlpA family protein disulfide reductase -
AL020_RS17455 () 84225..84380 + 156 Protein_91 4Fe-4S binding protein -
AL020_RS14375 () 84399..85676 + 1278 WP_002301194.1 ABC transporter permease -
AL020_RS14380 () 85686..86342 + 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
AL020_RS14385 () 86342..87718 + 1377 WP_002301195.1 ABC transporter permease -
AL020_RS14390 () 88004..89626 - 1623 WP_069314754.1 IS1182 family transposase ISEfa7 Transposase
AL020_RS14395 () 90278..91249 + 972 WP_002302275.1 radical SAM protein -
AL020_RS14400 () 91327..91563 - 237 WP_002322470.1 Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase VF
AL020_RS17010 () 91532..91663 - 132 WP_077828694.1 peptidylprolyl isomerase -
AL020_RS14405 () 91739..92122 - 384 WP_002330694.1 hypothetical protein -
AL020_RS14410 () 92155..92940 - 786 WP_002302270.1 histidinol phosphate phosphatase -
AL020_RS14415 () 93118..94218 + 1101 WP_002347701.1 extracellular solute-binding protein -
AL020_RS14420 () 94208..95032 + 825 WP_002302267.1 alkaline phosphatase family protein -
AL020_RS14425 () 95029..95844 + 816 WP_002330693.1 ABC transporter permease subunit -
AL020_RS14430 () 95841..96671 + 831 WP_002313180.1 ABC transporter permease -
AL020_RS14435 () 96678..97709 + 1032 WP_002302261.1 Spermidine/putrescine import ATP-binding protein PotA VF
AL020_RS17015 () 97816..99089 - 1274 Protein_106 ISL3 family transposase ISEfa11 Transposase
AL020_RS17600 () 99316..99501 + 186 WP_016922460.1 hypothetical protein -
AL020_RS14455 () 99625..100341 + 717 WP_002348630.1 aminotransferase class V-fold PLP-dependent enzyme -
AL020_RS17025 () 100243..100763 - 521 Protein_109 transposase -
AL020_RS14460 () 101051..101704 + 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
AL020_RS14465 () 101701..103020 + 1320 WP_002300494.1 HAMP domain-containing histidine kinase -
AL020_RS14470 () 103122..103802 - 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
AL020_RS14475 () 103933..104385 + 453 WP_000751236.1 hypothetical protein -
AL020_RS14480 () 104399..105088 + 690 WP_000718009.1 hypothetical protein -
AL020_RS14485 () 105213..107564 + 2352 WP_000344083.1 DUF1906 domain-containing protein -
AL020_RS14490 () 107644..108039 + 396 WP_002304891.1 hypothetical protein -
AL020_RS14495 () 108364..108981 + 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
AL020_RS14500 () 109022..109321 + 300 WP_000366408.1 BRCT domain-containing protein -
AL020_RS14505 () 109355..109522 + 168 WP_000824191.1 hypothetical protein -
AL020_RS14510 () 109567..110130 - 564 WP_002304893.1 Tn3 family transposase TnpR_ISPa40 Transposase
AL020_RS14515 () 110158..110838 - 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
AL020_RS14520 () 110908..111288 + 381 Protein_122 IS6 family transposase IS1216V Transposase
AL020_RS14525 () 111343..112652 + 1310 Protein_123 Bifunctional AAC/APH ARG
AL020_RS14530 () 112782..113954 - 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
AL020_RS14535 () 114584..115264 + 681 WP_010782692.1 IS6 family transposase IS1216E Transposase
AL020_RS14540 () 115604..116773 - 1170 WP_002300493.1 IS256 family transposase ISEfa13 Transposase
AL020_RS14545 () 116979..118526 - 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
AL020_RS14550 () 118628..118981 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
AL020_RS14555 () 118971..119165 - 195 WP_002285758.1 hypothetical protein -
AL020_RS17465 () 119364..120224 + 861 Protein_130 DUF2520 domain-containing protein -
AL020_RS14565 () 120236..121063 + 828 WP_002287874.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
AL020_RS14570 () 121078..121926 + 849 WP_002287875.1 pantoate--beta-alanine ligase -
AL020_RS14575 () 121936..122331 + 396 WP_002287876.1 aspartate 1-decarboxylase -
AL020_RS17050 () 122533..123357 + 825 Protein_134 IS3 family transposase ISEfa8 Transposase
AL020_RS17055 () 123280..123576 - 297 WP_073120200.1 IS3 family transposase ISEfa8 Transposase
AL020_RS14590 () 123928..125106 - 1179 WP_002346943.1 IS256 family transposase ISEf1 Transposase
AL020_RS14595 () 125357..125617 + 261 WP_002313174.1 hypothetical protein -
AL020_RS14600 () 125891..127183 + 1293 WP_002301811.1 IS256 family transposase ISBsu2 Transposase
AL020_RS14610 () 127752..128914 + 1163 WP_087043335.1 IS3 family transposase IS1485 Transposase
AL020_RS14615 () 129685..130419 + 735 WP_002301131.1 GntR family transcriptional regulator -
AL020_RS14620 () 130435..131604 + 1170 WP_002301130.1 SIS domain-containing protein -
AL020_RS14625 () 131620..132615 + 996 WP_002301128.1 tagatose-bisphosphate aldolase -
AL020_RS14630 () 132694..133620 + 927 WP_002298736.1 PEP phosphonomutase -
AL020_RS14635 () 133639..134889 + 1251 WP_002301126.1 PTS sugar transporter subunit IIC -
AL020_RS14640 () 135020..135973 + 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
AL020_RS14645 () 136081..137166 - 1086 WP_002301591.1 tyrosine recombinase XerS -
AL020_RS14655 () 139242..139760 - 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
AL020_RS14670 () 140878..142040 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
AL020_RS17470 () 142331..142441 + 111 Protein_149 transposase -
AL020_RS14675 () 142538..143014 - 477 WP_002300328.1 PTS glucose transporter subunit IIA -
AL020_RS14680 () 143027..144529 - 1503 WP_002289252.1 PTS transporter subunit EIIC -
AL020_RS14685 () 144543..145232 - 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
AL020_RS14690 () 145393..146211 + 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
AL020_RS14695 () 146441..146671 + 231 WP_002289255.1 resolvase -
AL020_RS17475 () 146894..146992 - 99 Protein_155 IS30 family transposase -
AL020_RS14705 () 147257..147712 - 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
AL020_RS17080 () 147955..149381 + 1427 WP_086953894.1 IS3 family transposase ISEfa10 Transposase
AL020_RS14720 () 149551..150513 - 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
AL020_RS14725 () 150515..151954 - 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
AL020_RS14730 () 152139..154085 + 1947 WP_002303302.1 sucrose-specific PTS transporter subunit IIBC -
AL020_RS14735 () 154349..155221 + 873 WP_002305879.1 ROK family protein -
AL020_RS14740 () 155556..156207 + 652 Protein_162 IS6 family transposase IS1216V Transposase
AL020_RS14745 () 156237..156836 - 600 WP_002322465.1 bacteriophage abortive infection AbiH family protein -
AL020_RS14750 () 156900..157499 - 600 WP_002301839.1 Tyrosine recombinase XerD VF
AL020_RS14755 () 157994..158212 - 219 Protein_165 IS256 family transposase ISLgar5 Transposase
AL020_RS14760 () 158453..158635 + 183 WP_002300846.1 hypothetical protein -
AL020_RS14765 () 158619..158804 + 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
AL020_RS14775 () 159047..160567 + 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
AL020_RS14780 () 160749..160943 + 195 WP_002285758.1 hypothetical protein -
AL020_RS14785 () 160933..161286 + 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
AL020_RS14790 () 161388..162935 + 1548 WP_002303202.1 IS66 family transposase ISRob1 Transposase
AL020_RS14795 () 163107..163679 - 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
AL020_RS14800 () 163686..164348 - 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
AL020_RS14805 () 164364..164879 - 516 WP_002300840.1 YjbQ family protein -
AL020_RS14810 () 164881..165165 - 285 WP_002300838.1 PTS sugar transporter subunit IIB -
AL020_RS14815 () 165199..166527 - 1329 WP_002300836.1 PTS galactitol transporter subunit IIC -
AL020_RS14820 () 166541..166996 - 456 WP_002300835.1 PTS sugar transporter subunit IIA -
AL020_RS14825 () 166999..168921 - 1923 Protein_178 PTS sugar transporter subunit IIA -
AL020_RS14830 () 168941..169849 - 909 WP_002332708.1 IS982 family transposase ISEfm1 Transposase
AL020_RS14835 () 170486..171805 - 1320 WP_002348774.1 IS1380 family transposase IS1678 Transposase
AL020_RS14840 () 172065..173243 - 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
AL020_RS14850 () 173615..173878 - 264 WP_002300807.1 uberolysin/carnocyclin family circular bacteriocin -
AL020_RS14855 () 173999..174952 + 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
AL020_RS14865 () 175921..176277 - 357 WP_002311569.1 hypothetical protein -
AL020_RS14870 () 176336..176515 - 180 WP_002300804.1 hypothetical protein -
AL020_RS14880 () 176960..177232 - 273 WP_002300801.1 hypothetical protein -
AL020_RS17750 () 177242..177397 - 156 WP_002300799.1 hypothetical protein -
AL020_RS14885 () 177413..177664 - 252 WP_002300797.1 hypothetical protein -
AL020_RS14890 () 177664..177870 - 207 WP_002305810.1 hypothetical protein -
AL020_RS14895 () 178313..178537 - 225 WP_002305809.1 hypothetical protein -
AL020_RS14900 () 178727..178849 + 123 WP_002295624.1 putative holin-like toxin -
AL020_RS14905 () 179008..179241 - 234 WP_002303482.1 hypothetical protein -
AL020_RS14910 () 179286..179771 - 486 Protein_193 single-stranded DNA-binding protein -
AL020_RS14920 () 179774..180673 - 900 WP_002303483.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
AL020_RS14925 () 180686..181282 - 597 WP_002303484.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
AL020_RS17755 () 181363..181512 - 150 WP_002295632.1 hypothetical protein -
AL020_RS14935 () 181628..183637 - 2010 WP_002303486.1 DNA topoisomerase III -
AL020_RS14940 () 183648..185117 - 1470 WP_002353594.1 toprim domain-containing protein -
AL020_RS14945 () 185178..187550 - 2373 WP_002305801.1 hypothetical protein -
AL020_RS14950 () 187960..189210 + 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
AL020_RS14955 () 189447..189788 - 342 WP_002295674.1 DUF5406 domain-containing protein -
AL020_RS14960 () 190407..190739 - 333 WP_002323647.1 hypothetical protein -
AL020_RS14965 () 191563..192603 - 1041 WP_002303636.1 replication initiator protein A -
AL020_RS17760 () 193769..193855 + 87 Protein_204 single-stranded DNA-binding protein -
AL020_RS17095 () 193955..194149 + 195 WP_002348857.1 hypothetical protein -
AL020_RS17100 () 194415..194633 + 219 Protein_206 type II toxin-antitoxin system RelE/ParE family toxin -
AL020_RS14970 () 194855..196003 - 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
AL020_RS14975 () 196020..196424 - 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
AL020_RS14980 () 196783..197037 + 255 WP_002303208.1 hypothetical protein -
AL020_RS14985 () 197038..197355 + 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
AL020_RS14990 () 197831..198511 + 681 WP_010782695.1 IS6 family transposase IS1216V Transposase
AL020_RS14995 () 198656..198844 + 189 WP_002296843.1 hypothetical protein -
AL020_RS15000 () 198957..199637 + 681 WP_002336713.1 IS6 family transposase IS1216E Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance