MGE detailed information
MGE type: Conjugative plasmid MGE length: 155425 bp
Accession: NZ_CP010232 Location: 1..155425 Organism: Escherichia coli strain S30 Replicon: plasmid A
Accession: NZ_CP010232 Location: 1..155425 Organism: Escherichia coli strain S30 Replicon: plasmid A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RG68_RS24535 () | 258..1433 | + | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| RG68_RS24540 () | 1457..4609 | + | 3153 | WP_000347934.1 | Efflux pump membrane transporter BepE | VF |
| RG68_RS24545 () | 4679..5158 | - | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| RG68_RS24550 () | 5259..5963 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| RG68_RS24555 () | 6027..6296 | - | 270 | Protein_4 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| RG68_RS29035 () | 6422..6772 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| RG68_RS24570 () | 6975..7988 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| RG68_RS24580 () | 8133..8630 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| RG68_RS28635 () | 8742..9032 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| RG68_RS24590 () | 9038..9829 | + | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| RG68_RS24595 () | 9993..10340 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| RG68_RS24600 () | 10334..10666 | + | 333 | Protein_11 | IS6 family transposase IS15 | Transposase |
| RG68_RS24605 () | 10723..11427 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| RG68_RS24615 () | 11556..12320 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| RG68_RS24625 () | 12813..13397 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| RG68_RS24630 () | 13397..14635 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| RG68_RS24635 () | 14632..15537 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| RG68_RS24640 () | 15659..16363 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| RG68_RS24645 () | 16425..17105 | - | 681 | Protein_18 | hypothetical protein | - |
| RG68_RS24650 () | 17156..17383 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| RG68_RS24655 () | 17407..17598 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| RG68_RS24660 () | 18080..18622 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| RG68_RS24665 () | 18635..19495 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| RG68_RS24670 () | 19638..20543 | + | 906 | Protein_23 | IS4 family transposase IS10R | Transposase |
| RG68_RS24675 () | 20592..21296 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| RG68_RS24680 () | 21598..22458 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| RG68_RS27975 () | 22608..22706 | - | 99 | Protein_26 | IS1 family transposase | - |
| RG68_RS24690 () | 22735..24045 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| RG68_RS24695 () | 24330..24731 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| RG68_RS29040 () | 24664..24921 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| RG68_RS24705 () | 25014..25667 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| RG68_RS29200 () | 25765..25905 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| RG68_RS24720 () | 26607..27464 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| RG68_RS24725 () | 27457..27531 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| RG68_RS24735 () | 27757..28017 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| RG68_RS24740 () | 28256..28829 | - | 574 | Protein_35 | DUF2726 domain-containing protein | - |
| RG68_RS24745 () | 28867..29076 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| RG68_RS24750 () | 29122..29583 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| RG68_RS24755 () | 29826..30038 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| RG68_RS24760 () | 30176..30736 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| RG68_RS24765 () | 30791..31537 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| RG68_RS24770 () | 31557..36827 | - | 5271 | WP_072769080.1 | Multifunctional conjugation protein TraI | Relaxase |
| RG68_RS24775 () | 36827..39088 | - | 2262 | WP_073546701.1 | type IV conjugative transfer system coupling protein TraD | - |
| RG68_RS24780 () | 39341..40072 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| RG68_RS24785 () | 40104..40607 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| RG68_RS24790 () | 40622..43444 | - | 2823 | WP_001007026.1 | conjugal transfer mating pair stabilization protein TraG | - |
| RG68_RS24795 () | 43441..44814 | - | 1374 | WP_001137358.1 | conjugal transfer protein TraH | - |
| RG68_RS24800 () | 44814..45176 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| RG68_RS24805 () | 45106..45651 | - | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| RG68_RS24810 () | 45638..45922 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| RG68_RS24815 () | 46041..46388 | - | 348 | WP_001287893.1 | conjugal transfer protein TrbA | - |
| RG68_RS24820 () | 46404..47147 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| RG68_RS24825 () | 47140..47397 | - | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| RG68_RS24830 () | 47424..49232 | - | 1809 | WP_000821821.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| RG68_RS24835 () | 49229..49867 | - | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| RG68_RS24840 () | 49895..50347 | - | 453 | WP_000069427.1 | hypothetical protein | - |
| RG68_RS24845 () | 50377..50838 | - | 462 | WP_000277845.1 | hypothetical protein | - |
| RG68_RS24850 () | 50864..51856 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| RG68_RS24855 () | 51853..52485 | - | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| RG68_RS24860 () | 52482..52868 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| RG68_RS24865 () | 52865..55492 | - | 2628 | WP_001064268.1 | type IV secretion system protein TraC | - |
| RG68_RS24870 () | 55652..55873 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| RG68_RS24875 () | 56008..56523 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| RG68_RS24880 () | 56520..56771 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| RG68_RS24885 () | 56768..57085 | - | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| RG68_RS24890 () | 57082..57654 | - | 573 | WP_000002780.1 | conjugal transfer protein TraP | - |
| RG68_RS24895 () | 57644..59071 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| RG68_RS24900 () | 59071..59775 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| RG68_RS24905 () | 59786..60352 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| RG68_RS24910 () | 60374..60685 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| RG68_RS24915 () | 60700..61059 | - | 360 | WP_072649514.1 | type IV conjugative transfer system pilin TraA | - |
| RG68_RS24920 () | 61093..61320 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| RG68_RS24925 () | 61414..62100 | - | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| RG68_RS24930 () | 62291..62674 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| RG68_RS24940 () | 62951..63598 | + | 648 | WP_000614936.1 | hypothetical protein | VF |
| RG68_RS24945 () | 63895..64716 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| RG68_RS24950 () | 64838..65125 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| RG68_RS29205 () | 65150..65356 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| RG68_RS24970 () | 66047..66205 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 66249..66473 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 66249..66473 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 66249..66473 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 66249..66473 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| RG68_RS29045 () | 66285..66473 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| RG68_RS24980 () | 66485..67204 | - | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| RG68_RS24985 () | 67201..67635 | - | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| RG68_RS24990 () | 67690..69648 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| RG68_RS24995 () | 69707..69940 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| RG68_RS25000 () | 69996..70523 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| RG68_RS25015 () | 70996..71262 | - | 267 | WP_072254135.1 | hypothetical protein | - |
| RG68_RS25025 () | 71414..71977 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| RG68_RS25030 () | 72023..73384 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| RG68_RS25035 () | 73436..73666 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| RG68_RS29210 () | 74344..74672 | + | 329 | Protein_89 | pilus assembly protein | - |
| RG68_RS25060 () | 74660..74842 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| RG68_RS25065 () | 74842..75303 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| RG68_RS25070 () | 75303..75605 | - | 303 | WP_072256028.1 | antirestriction protein | - |
| RG68_RS25080 () | 76130..77101 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| RG68_RS25085 () | 77154..77851 | - | 698 | Protein_94 | IS1 family transposase IS1R | Transposase |
| RG68_RS25105 () | 77905..78237 | - | 333 | Protein_95 | hypothetical protein | - |
| RG68_RS29215 () | 78306..78644 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| RG68_RS25120 () | 79456..80427 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| RG68_RS25125 () | 80427..81593 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| RG68_RS28010 () | 81894..82592 | - | 699 | Protein_99 | IS1 family transposase IS1G | Transposase |
| RG68_RS25145 () | 82748..84250 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| RG68_RS25150 () | 84859..85308 | - | 450 | WP_000238252.1 | hypothetical protein | - |
| RG68_RS25155 () | 85426..85905 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| RG68_RS25165 () | 86345..86572 | + | 228 | Protein_103 | malate dehydrogenase | - |
| RG68_RS25170 () | 86569..86700 | - | 132 | Protein_104 | phosphopyruvate hydratase | - |
| RG68_RS28020 () | 86698..86955 | + | 258 | Protein_105 | Tn3 family transposase | - |
| RG68_RS25175 () | 87189..88046 | - | 858 | WP_000968140.1 | Manganese transport system membrane protein MntB | ARG |
| RG68_RS25180 () | 88043..88900 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| RG68_RS25185 () | 88897..89724 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| RG68_RS25190 () | 89724..90638 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| RG68_RS28030 () | 90995..91693 | + | 699 | Protein_110 | IS1 family transposase IS1G | Transposase |
| RG68_RS25230 () | 91874..92387 | - | 514 | Protein_111 | DUF4113 domain-containing protein | - |
| RG68_RS29220 () | 92448..92552 | - | 105 | Protein_112 | AAA family ATPase | - |
| RG68_RS28035 () | 92554..92877 | - | 324 | Protein_113 | IS21 family transposase IS21 | Transposase |
| RG68_RS25250 () | 93126..94339 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
| RG68_RS25265 () | 94884..95861 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| RG68_RS25270 () | 96146..96886 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| RG68_RS25275 () | 97007..97195 | - | 189 | WP_032146647.1 | hypothetical protein | - |
| RG68_RS25280 () | 97570..98472 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| RG68_RS25285 () | 98541..99650 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| RG68_RS25295 () | 100083..101036 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| RG68_RS28040 () | 102309..102467 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| RG68_RS25325 () | 102651..103864 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| RG68_RS25330 () | 104012..104337 | - | 326 | Protein_123 | IS3 family transposase ISLad1 | Transposase |
| RG68_RS25335 () | 105318..106505 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| RG68_RS25340 () | 106502..108442 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| RG68_RS25345 () | 108446..109816 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| RG68_RS25355 () | 110290..110484 | + | 195 | Protein_127 | IS200-IS605 family transposase IS200C | Transposase |
| RG68_RS25360 () | 110613..111554 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| RG68_RS25370 () | 111789..113177 | - | 1389 | Protein_129 | ISNCY family transposase ISKpn21 | Transposase |
| RG68_RS28675 () | 113487..113636 | - | 150 | Protein_130 | IS3 family transposase IS2 | Transposase |
| RG68_RS25385 () | 113814..115007 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| RG68_RS25400 () | 116230..117466 | - | 1237 | Protein_132 | IS3 family transposase IS2 | Transposase |
| RG68_RS25410 () | 118093..118386 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| RG68_RS25415 () | 118444..118643 | - | 200 | Protein_134 | lysis protein | - |
| RG68_RS28055 () | 119197..120300 | + | 1104 | Protein_135 | IS481 family transposase ISKpn28 | Transposase |
| RG68_RS25440 () | 121536..122651 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| RG68_RS25445 () | 122791..126450 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| RG68_RS25450 () | 126554..127783 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| RG68_RS25455 () | 127868..128824 | + | 957 | WP_064055648.1 | Ferri-bacillibactin esterase BesA | VF |
| RG68_RS25460 () | 128869..131046 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| RG68_RS28060 () | 131281..131980 | + | 700 | Protein_141 | IS1 family transposase IS1G | Transposase |
| RG68_RS25480 () | 131991..132194 | - | 204 | WP_001259759.1 | colicin V family bacteriocin | - |
| RG68_RS29055 () | 132172..132408 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| RG68_RS25495 () | 132872..133153 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| RG68_RS25505 () | 133326..133493 | + | 168 | Protein_145 | colicin-B | - |
| RG68_RS25510 () | 133511..134038 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| RG68_RS25520 () | 134282..135097 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| RG68_RS25525 () | 135147..135500 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| RG68_RS25530 () | 135678..136469 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| RG68_RS25535 () | 136466..137155 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| RG68_RS25540 () | 137199..137549 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| RG68_RS25545 () | 138081..141902 | - | 3822 | WP_073546704.1 | hypothetical protein | - |
| RG68_RS29225 () | 142146..142307 | + | 162 | WP_000251882.1 | hypothetical protein | - |
| RG68_RS25550 () | 142325..142672 | - | 348 | WP_000142450.1 | hypothetical protein | - |
| RG68_RS25555 () | 142974..143456 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| RG68_RS25560 () | 143573..144421 | - | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| RG68_RS25565 () | 144467..144748 | - | 282 | WP_000969990.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| RG68_RS28685 () | 144745..144822 | - | 78 | Protein_158 | toxin-antitoxin system protein | - |
| RG68_RS25575 () | 144855..146606 | - | 1752 | Protein_159 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| RG68_RS25580 () | 146595..147002 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| RG68_RS25585 () | 147140..148024 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| RG68_RS25590 () | 148056..149255 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| RG68_RS25595 () | 149361..149987 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| RG68_RS25600 () | 150019..150261 | - | 243 | WP_000844627.1 | transposase | - |
| RG68_RS25615 () | 150648..151484 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| RG68_RS25620 () | 151484..152287 | - | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| RG68_RS25625 () | 152348..153163 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| RG68_RS25635 () | 153493..153669 | + | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| RG68_RS25640 () | 153851..154606 | - | 756 | Protein_169 | IS110 family transposase IS5075 | Transposase |
| RG68_RS25645 () | 154659..155363 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|