MGE detailed information
MGE type: Conjugative plasmid MGE length: 146552 bp
Accession: NZ_CP010222 Location: 1..146552 Organism: Escherichia coli strain M19 Replicon: plasmid A
Accession: NZ_CP010222 Location: 1..146552 Organism: Escherichia coli strain M19 Replicon: plasmid A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RG63_RS26520 () | 46..465 | + | 420 | Protein_0 | IS110 family transposase | - |
| RG63_RS26525 () | 493..819 | - | 327 | Protein_1 | protein ImpB | - |
| RG63_RS26530 () | 819..1256 | - | 438 | WP_073519984.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| RG63_RS26535 () | 1253..1501 | - | 249 | WP_073519983.1 | DinI-like family protein | - |
| RG63_RS26545 () | 1895..2791 | + | 897 | WP_106423823.1 | DUF1281 domain-containing protein | - |
| RG63_RS26550 () | 3106..4032 | + | 927 | WP_073519982.1 | hypothetical protein | - |
| RG63_RS26555 () | 4157..5029 | - | 873 | WP_073519981.1 | LysR family transcriptional regulator | - |
| RG63_RS26560 () | 5154..5861 | + | 708 | WP_073519980.1 | AzlC family ABC transporter permease | - |
| RG63_RS26565 () | 5858..6166 | + | 309 | WP_073519979.1 | AzlD domain-containing protein | - |
| RG63_RS26570 () | 6209..6904 | + | 696 | WP_073519978.1 | alpha/beta hydrolase | - |
| RG63_RS28505 () | 7007..7979 | - | 973 | Protein_10 | IS110 family transposase | - |
| RG63_RS26585 () | 8558..9034 | + | 477 | Protein_11 | antirestriction protein ArdA | - |
| RG63_RS29570 () | 9096..9233 | + | 138 | WP_172944237.1 | hypothetical protein | - |
| RG63_RS26590 () | 9480..9734 | + | 255 | WP_160537948.1 | DNA polymerase III subunit theta | - |
| RG63_RS29190 () | 9911..10132 | - | 222 | WP_154813206.1 | hypothetical protein | - |
| RG63_RS29575 () | 10197..10346 | - | 150 | WP_157920373.1 | hypothetical protein | - |
| RG63_RS26595 () | 10417..10974 | + | 558 | WP_073519975.1 | single-stranded DNA-binding protein | - |
| RG63_RS26600 () | 11026..11268 | + | 243 | WP_073519974.1 | DUF905 domain-containing protein | - |
| RG63_RS26605 () | 11338..13335 | + | 1998 | WP_073519973.1 | ParB/RepB/Spo0J family partition protein | - |
| RG63_RS26610 () | 13376..13810 | + | 435 | WP_097455818.1 | conjugation system SOS inhibitor PsiB | - |
| RG63_RS26615 () | 13807..14536 | + | 730 | Protein_20 | plasmid SOS inhibition protein A | - |
| RG63_RS26620 () | 14533..14847 | + | 315 | WP_073519971.1 | theronine dehydrogenase | - |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| RG63_RS26630 () | 15057..15218 | + | 162 | WP_073519970.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| RG63_RS28510 () | 15392..15766 | + | 375 | WP_171769349.1 | hypothetical protein | - |
| RG63_RS29200 () | 15951..16362 | - | 412 | Protein_24 | hypothetical protein | - |
| RG63_RS26650 () | 16659..17003 | + | 345 | WP_073519969.1 | hypothetical protein | - |
| RG63_RS26655 () | 17147..17968 | + | 822 | WP_073519968.1 | DUF945 domain-containing protein | - |
| RG63_RS26660 () | 18264..18773 | - | 510 | WP_073519994.1 | transglycosylase SLT domain-containing protein | - |
| RG63_RS26665 () | 19197..19583 | + | 387 | WP_073519967.1 | relaxosome protein TraM | - |
| RG63_RS26670 () | 19772..20194 | + | 423 | WP_073519966.1 | PAS domain-containing protein | - |
| RG63_RS26675 () | 20551..20778 | + | 228 | WP_073519965.1 | conjugal transfer relaxosome protein TraY | - |
| RG63_RS26680 () | 20812..21171 | + | 360 | WP_073519964.1 | type IV conjugative transfer system pilin TraA | - |
| RG63_RS26685 () | 21186..21497 | + | 312 | WP_073519963.1 | type IV conjugative transfer system protein TraL | - |
| RG63_RS26690 () | 21519..22085 | + | 567 | WP_073519962.1 | type IV conjugative transfer system protein TraE | - |
| RG63_RS26695 () | 22096..22803 | + | 708 | WP_149025695.1 | type-F conjugative transfer system secretin TraK | - |
| RG63_RS26700 () | 22803..24251 | + | 1449 | WP_073519960.1 | conjugal transfer protein TraB | - |
| RG63_RS26705 () | 24220..24804 | + | 585 | WP_073519959.1 | conjugal transfer protein TraP | - |
| RG63_RS26710 () | 24758..25111 | + | 354 | WP_077897972.1 | conjugal transfer protein TrbD | - |
| RG63_RS26715 () | 25108..25623 | + | 516 | WP_073519958.1 | type IV conjugative transfer system lipoprotein TraV | - |
| RG63_RS26720 () | 25758..25979 | + | 222 | WP_073519957.1 | conjugal transfer protein TraR | - |
| RG63_RS26725 () | 25972..26448 | + | 477 | WP_073519956.1 | hypothetical protein | - |
| RG63_RS26730 () | 26445..26915 | + | 471 | WP_073519955.1 | hypothetical protein | - |
| RG63_RS26735 () | 26912..27307 | + | 396 | WP_073519954.1 | hypothetical protein | - |
| RG63_RS26740 () | 27325..29952 | + | 2628 | WP_073519953.1 | type IV secretion system protein TraC | - |
| RG63_RS26745 () | 29949..30335 | + | 387 | WP_073519952.1 | type-F conjugative transfer system protein TrbI | - |
| RG63_RS26750 () | 30332..30964 | + | 633 | WP_073519951.1 | type-F conjugative transfer system protein TraW | - |
| RG63_RS26755 () | 30961..31953 | + | 993 | WP_073519950.1 | conjugal transfer pilus assembly protein TraU | - |
| RG63_RS26760 () | 31962..32600 | + | 639 | WP_073519949.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| RG63_RS26765 () | 32597..32977 | + | 381 | WP_073519948.1 | hypothetical protein | - |
| RG63_RS26770 () | 33213..35096 | + | 1884 | WP_077897973.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| RG63_RS26775 () | 35108..35575 | + | 468 | WP_073519947.1 | hypothetical protein | - |
| RG63_RS26780 () | 35586..36329 | + | 744 | WP_073519946.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| RG63_RS26785 () | 36343..36708 | + | 366 | WP_073519945.1 | hypothetical protein | - |
| RG63_RS26795 () | 37094..37381 | + | 288 | WP_073519943.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| RG63_RS26800 () | 37362..37916 | + | 555 | WP_073519942.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| RG63_RS26805 () | 37929..38420 | + | 492 | WP_073519941.1 | hypothetical protein | - |
| RG63_RS26815 () | 38825..40243 | + | 1419 | WP_073519939.1 | conjugal transfer protein TraH | - |
| RG63_RS26820 () | 40240..43092 | + | 2853 | WP_073519938.1 | conjugal transfer mating pair stabilization protein TraG | - |
| RG63_RS26825 () | 43113..43610 | + | 498 | WP_073519937.1 | surface exclusion protein | - |
| RG63_RS26830 () | 43642..44373 | + | 732 | WP_123006582.1 | complement resistance protein TraT | - |
| RG63_RS26835 () | 44970..47123 | + | 2154 | WP_073519936.1 | type IV conjugative transfer system coupling protein TraD | - |
| RG63_RS26840 () | 47123..52393 | + | 5271 | WP_073521418.1 | conjugative transfer relaxase/helicase TraI | - |
| RG63_RS26845 () | 52410..53144 | + | 735 | WP_073519934.1 | conjugal transfer pilus acetylase TraX | - |
| RG63_RS26850 () | 53199..53759 | + | 561 | Protein_63 | fertility inhibition protein FinO | - |
| RG63_RS26855 () | 53895..54101 | + | 207 | WP_073519933.1 | hypothetical protein | - |
| RG63_RS29755 () | 54373..54474 | - | 102 | Protein_65 | transposase | - |
| RG63_RS26860 () | 54621..55505 | + | 885 | WP_034173833.1 | alpha/beta hydrolase | - |
| RG63_RS26865 () | 55530..56258 | - | 729 | WP_034173832.1 | transcriptional regulator NanR | - |
| RG63_RS26870 () | 56328..57413 | + | 1086 | WP_077897982.1 | hypothetical protein | - |
| RG63_RS26875 () | 57550..58449 | + | 900 | WP_073519990.1 | N-acetylneuraminate lyase | - |
| RG63_RS26880 () | 58509..59384 | + | 876 | WP_073519989.1 | N-acetylmannosamine kinase | - |
| RG63_RS26885 () | 59455..60921 | + | 1467 | WP_073519932.1 | MFS transporter | - |
| RG63_RS26890 () | 60937..61746 | + | 810 | WP_073519931.1 | alpha/beta hydrolase | - |
| RG63_RS26895 () | 61800..62510 | + | 711 | WP_073519930.1 | N-acetylneuraminic acid channel protein | - |
| RG63_RS26900 () | 62520..63629 | + | 1110 | WP_073519929.1 | N-acetylneuraminate epimerase | - |
| RG63_RS26905 () | 64150..64371 | - | 222 | Protein_75 | IS1 family transposase | - |
| RG63_RS26910 () | 64370..64558 | - | 189 | Protein_76 | transposase | - |
| RG63_RS26920 () | 64962..65534 | + | 573 | WP_073519927.1 | hypothetical protein | - |
| RG63_RS26925 () | 65568..66788 | + | 1221 | WP_073519926.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| RG63_RS26930 () | 66790..68943 | + | 2154 | WP_073519925.1 | peptidase domain-containing ABC transporter | - |
| RG63_RS26935 () | 68987..69721 | + | 735 | WP_073519924.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| RG63_RS26940 () | 69776..70336 | + | 561 | Protein_81 | fertility inhibition protein FinO | - |
| RG63_RS29580 () | 70491..70685 | - | 195 | WP_157916191.1 | hypothetical protein | - |
| RG63_RS26950 () | 70925..71385 | + | 461 | Protein_83 | thermonuclease family protein | - |
| RG63_RS26955 () | 71431..71640 | + | 210 | WP_032334801.1 | hemolysin expression modulator Hha | - |
| RG63_RS26960 () | 71678..72268 | + | 591 | WP_073521419.1 | DUF2726 domain-containing protein | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| RG63_RS26970 () | 72546..72695 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | - |
| RG63_RS26975 () | 72896..73153 | + | 258 | WP_073519922.1 | replication regulatory protein RepA | - |
| RG63_RS26985 () | 73385..73459 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| RG63_RS26990 () | 73452..74280 | + | 829 | Protein_89 | incFII family plasmid replication initiator RepA | - |
| RG63_RS29585 () | 74982..75140 | + | 159 | WP_073519919.1 | hypothetical protein | - |
| RG63_RS27010 () | 75195..75464 | + | 270 | WP_073519918.1 | hypothetical protein | - |
| RG63_RS27015 () | 75461..75676 | + | 216 | WP_073519917.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG63_RS27020 () | 75828..76133 | + | 306 | WP_073521420.1 | hypothetical protein | - |
| RG63_RS27025 () | 76130..76402 | - | 273 | WP_046201741.1 | hypothetical protein | - |
| RG63_RS29590 () | 76395..76718 | - | 324 | Protein_95 | recombinase family protein | - |
| RG63_RS27045 () | 78001..78636 | + | 636 | WP_073519914.1 | CPBP family intramembrane metalloprotease | - |
| RG63_RS27050 () | 78739..79992 | + | 1254 | WP_073519913.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| RG63_RS27055 () | 79992..82181 | + | 2190 | WP_073519912.1 | peptidase domain-containing ABC transporter | - |
| RG63_RS27065 () | 82693..85740 | - | 3048 | Protein_99 | Tn3 family transposase | - |
| RG63_RS27070 () | 85890..86468 | + | 579 | WP_001400936.1 | recombinase family protein | - |
| RG63_RS27075 () | 86461..86733 | + | 273 | WP_046201741.1 | hypothetical protein | - |
| RG63_RS27080 () | 86773..86964 | - | 192 | Protein_102 | hypothetical protein | - |
| RG63_RS27085 () | 87649..88068 | + | 420 | WP_073519911.1 | Exc2 family lipoprotein | - |
| RG63_RS27090 () | 88438..88791 | + | 354 | WP_077897977.1 | hypothetical protein | - |
| RG63_RS27095 () | 88803..89201 | + | 399 | WP_073519910.1 | hypothetical protein | - |
| RG63_RS27105 () | 89635..90209 | - | 575 | Protein_106 | helix-turn-helix domain-containing protein | - |
| RG63_RS27110 () | 90293..90478 | - | 186 | WP_077897978.1 | LacI family transcriptional regulator | - |
| RG63_RS27115 () | 90512..90889 | - | 378 | WP_157916187.1 | GntR family transcriptional regulator | - |
| RG63_RS27120 () | 91682..95785 | + | 4104 | WP_073519907.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG63_RS29240 () | 96027..97103 | + | 1077 | Protein_110 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG63_RS29245 () | 97125..98318 | + | 1194 | WP_095374788.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG63_RS27130 () | 98543..99181 | - | 639 | WP_073519905.1 | ParB N-terminal domain-containing protein | - |
| RG63_RS27135 () | 99166..100398 | - | 1233 | WP_073519904.1 | phosphoadenosine phosphosulfate reductase | - |
| RG63_RS28530 () | 100922..101135 | + | 214 | Protein_114 | IS1 family transposase | - |
| RG63_RS28535 () | 101284..102041 | + | 758 | Protein_115 | IS3 family transposase | - |
| RG63_RS28540 () | 102073..102336 | - | 264 | WP_077897983.1 | HNH endonuclease | - |
| RG63_RS27160 () | 102389..103410 | + | 1022 | Protein_117 | IS21 family transposase | - |
| RG63_RS27165 () | 103413..104168 | + | 756 | WP_213056195.1 | IS21-like element helper ATPase IstB | - |
| RG63_RS27170 () | 104252..104761 | - | 510 | Protein_119 | HNH endonuclease | - |
| RG63_RS29250 () | 104884..105124 | - | 241 | Protein_120 | transposase zinc-binding domain-containing protein | - |
| RG63_RS27180 () | 105910..106209 | + | 300 | WP_073519900.1 | adhesin biosynthesis transcription regulatory family protein | - |
| RG63_RS27185 () | 106217..106759 | + | 543 | WP_073519899.1 | type 1 fimbrial protein | - |
| RG63_RS27190 () | 106774..109218 | + | 2445 | WP_073519898.1 | F4 (K88) fimbrial usher FaeD | - |
| RG63_RS27195 () | 109211..109987 | + | 777 | WP_073519897.1 | F4 (K88) fimbrial chaperone FaeE | - |
| RG63_RS27200 () | 110022..110513 | + | 492 | WP_073519896.1 | DUF5462 family protein | - |
| RG63_RS27205 () | 110735..111532 | + | 798 | WP_073519895.1 | hypothetical protein | - |
| RG63_RS27210 () | 111730..112527 | + | 798 | WP_073519894.1 | fimbrial protein | - |
| RG63_RS27215 () | 112557..113321 | + | 765 | WP_073519893.1 | fimbrial protein | - |
| RG63_RS27220 () | 113338..114099 | + | 762 | WP_073519892.1 | fimbrial protein | - |
| RG63_RS27225 () | 114341..114625 | - | 285 | WP_077897980.1 | PbsX family transcriptional regulator | - |
| RG63_RS27230 () | 114709..118638 | - | 3930 | WP_073519890.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG63_RS27240 () | 119560..119985 | + | 426 | Protein_132 | IS3 family transposase | - |
| RG63_RS28545 () | 120261..121260 | + | 1000 | Protein_133 | colicin transporter | - |
| RG63_RS27265 () | 121590..121859 | + | 270 | Protein_134 | transcriptional regulator | - |
| RG63_RS29260 () | 122195..122301 | + | 107 | Protein_135 | IS110 family transposase | - |
| RG63_RS27270 () | 122303..122512 | + | 210 | Protein_136 | hypothetical protein | - |
| RG63_RS27275 () | 122765..123613 | - | 849 | WP_073519985.1 | hypothetical protein | - |
| RG63_RS27285 () | 124295..124441 | + | 147 | WP_073519886.1 | serine/threonine protein kinase | - |
| RG63_RS27290 () | 124604..125344 | + | 741 | WP_073519885.1 | site-specific integrase | - |
| RG63_RS27295 () | 125629..126606 | - | 978 | WP_000361618.1 | RepB family plasmid replication initiator protein | - |
| RG63_RS29265 () | 127256..127536 | - | 281 | Protein_141 | integrase core domain-containing protein | - |
| RG63_RS27315 () | 127535..127822 | - | 288 | WP_001270417.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG63_RS27320 () | 127819..128070 | - | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| RG63_RS27325 () | 128235..128447 | - | 213 | WP_032334873.1 | hypothetical protein | - |
| RG63_RS27335 () | 128821..130026 | + | 1206 | WP_000817644.1 | AAA family ATPase | - |
| RG63_RS27340 () | 130023..130985 | + | 963 | WP_000756325.1 | ParB/RepB/Spo0J family partition protein | - |
| RG63_RS28550 () | 131219..131975 | + | 757 | Protein_147 | IS4 family transposase | - |
| RG63_RS29595 () | 132089..132564 | + | 476 | Protein_148 | DUF1281 domain-containing protein | - |
| RG63_RS27370 () | 132904..134049 | + | 1146 | WP_073519881.1 | IS21 family transposase | - |
| RG63_RS27375 () | 134049..134597 | + | 549 | Protein_150 | ATP-binding protein | - |
| RG63_RS27385 () | 134909..136681 | + | 1773 | WP_073519780.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| RG63_RS27390 () | 136694..145819 | + | 9126 | Protein_152 | contact-dependent inhibition effector tRNA nuclease | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|