NZ_AP0266551318222..1467660

MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 149439 bp
Accession: NZ_AP026655        Location: 1318222..1467660         Organism: Enterococcus faecium strain GK923       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQH82_RS06635 (EfmGK923_12800) 1313272..1313985 + 714 WP_002296656.1 HAD family phosphatase -
OQH82_RS06640 (EfmGK923_12810) 1314192..1314341 - 150 WP_002296658.1 hypothetical protein -
OQH82_RS06645 (EfmGK923_12820) 1314737..1314937 + 201 WP_002293303.1 cold-shock protein -
OQH82_RS06650 (EfmGK923_12840) 1316128..1316493 - 366 WP_002296662.1 TIGR02328 family protein -
OQH82_RS06655 (EfmGK923_12850) 1316569..1316814 - 246 WP_002296663.1 helix-turn-helix transcriptional regulator -
OQH82_RS06660 (EfmGK923_12860) 1316884..1317138 - 255 WP_002296665.1 hypothetical protein -
OQH82_RS06665 (EfmGK923_12870) 1317302..1317625 - 324 WP_002321681.1 hypothetical protein -
OQH82_RS06675 (EfmGK923_12880) 1318270..1318767 - 498 WP_002296667.1 isochorismatase family cysteine hydrolase -
OQH82_RS06680 (EfmGK923_12890) 1318807..1319616 - 810 WP_265169903.1 Cof-type HAD-IIB family hydrolase -
OQH82_RS06685 (EfmGK923_12900) 1319950..1320807 + 858 WP_002296670.1 glycosyltransferase family 8 protein -
OQH82_RS06690 (EfmGK923_12910) 1320800..1321702 + 903 WP_002296671.1 glycosyltransferase family 8 protein -
OQH82_RS06695 (EfmGK923_12920) 1321735..1322085 + 351 WP_002296672.1 iron-sulfur cluster biosynthesis family protein -
OQH82_RS06700 (EfmGK923_12930) 1322134..1323057 + 924 WP_002303839.1 magnesium transporter CorA family protein -
OQH82_RS06705 (EfmGK923_12940) 1323135..1324028 + 894 WP_002300977.1 putative oxidoreductase YghA VF
OQH82_RS06710 (EfmGK923_12950) 1324066..1324629 + 564 WP_002296677.1 alkaline shock response membrane anchor protein AmaP -
OQH82_RS06715 (EfmGK923_12960) 1324643..1324831 + 189 WP_002291274.1 DUF2273 domain-containing protein -
OQH82_RS06720 (EfmGK923_12970) 1324844..1325746 + 903 WP_002296679.1 Asp23/Gls24 family envelope stress response protein -
OQH82_RS06725 (EfmGK923_12980) 1325778..1326020 + 243 WP_002291278.1 GlsB/YeaQ/YmgE family stress response membrane protein -
OQH82_RS06730 1326276..1326647 - 372 WP_002295142.1 hypothetical protein -
OQH82_RS06735 1326853..1328405 + 1553 Protein_1294 IS1182 family transposase -
OQH82_RS06740 (EfmGK923_13010) 1328839..1329066 - 228 WP_002295139.1 helix-turn-helix transcriptional regulator -
OQH82_RS06745 (EfmGK923_13020) 1329075..1329548 - 474 WP_002295138.1 DUF2975 domain-containing protein -
OQH82_RS06750 (EfmGK923_13030) 1330779..1331345 + 567 WP_002295947.1 alkaline shock response membrane anchor protein AmaP -
OQH82_RS06755 (EfmGK923_13040) 1331358..1331546 + 189 WP_002295945.1 DUF2273 domain-containing protein -
OQH82_RS06760 (EfmGK923_13050) 1331559..1332116 + 558 WP_002295944.1 Asp23/Gls24 family envelope stress response protein -
OQH82_RS06765 (EfmGK923_13060) 1332148..1332390 + 243 WP_002290686.1 GlsB/YeaQ/YmgE family stress response membrane protein -
OQH82_RS06770 1332472..1332549 + 78 Protein_1301 dihydrofolate reductase -
OQH82_RS06775 (EfmGK923_13070) 1332730..1333944 + 1215 WP_002296683.1 ammonium transporter -
OQH82_RS06780 (EfmGK923_13080) 1333975..1334193 + 219 Protein_1303 putative glutamate/gamma-aminobutyrate antiporter VF
OQH82_RS06785 (EfmGK923_13090) 1334612..1335107 + 496 Protein_1304 trimethoprim-resistant dihydrofolate reductase DfrF -
OQH82_RS06790 (EfmGK923_13100) 1335212..1335868 + 657 WP_002303420.1 hypothetical protein -
OQH82_RS06795 (EfmGK923_13110) 1336050..1336580 + 531 WP_002303421.1 dihydrofolate reductase family protein -
OQH82_RS06800 (EfmGK923_13120) 1337126..1337368 + 243 WP_002303262.1 DUF3781 domain-containing protein -
OQH82_RS06805 (EfmGK923_13130) 1337365..1337835 + 471 WP_002303261.1 GyrI-like domain-containing protein -
OQH82_RS06810 (EfmGK923_13140) 1337963..1339177 + 1215 WP_002303260.1 XRE family transcriptional regulator -
OQH82_RS06815 (EfmGK923_13150) 1340166..1340375 + 210 WP_002303258.1 hypothetical protein -
OQH82_RS06820 (EfmGK923_13160) 1340487..1342100 + 1614 WP_002303255.1 hypothetical protein ; Integrase Integrase
OQH82_RS06825 (EfmGK923_13170) 1342135..1343346 + 1212 Protein_1312 amino acid permease -
OQH82_RS06830 (EfmGK923_13180) 1343369..1344295 + 927 WP_002295938.1 glutaminase A -
OQH82_RS06835 (EfmGK923_13200) 1344503..1345965 + 1463 Protein_1314 hypothetical protein -
OQH82_RS06840 (EfmGK923_13210) 1346186..1347949 + 1764 WP_002287770.1 1-deoxy-D-xylulose-5-phosphate synthase -
OQH82_RS06845 (EfmGK923_13220) 1348033..1348491 + 459 WP_002295936.1 ASCH domain-containing protein -
OQH82_RS06850 (EfmGK923_13230) 1348600..1349283 + 684 WP_002287767.1 N-acetylmannosamine-6-phosphate 2-epimerase -
OQH82_RS06855 (EfmGK923_13240) 1349430..1350044 + 615 WP_002287766.1 flavin reductase family protein -
OQH82_RS06860 (EfmGK923_13250) 1350060..1350266 + 207 WP_002287763.1 hypothetical protein -
OQH82_RS06865 (EfmGK923_13260) 1350296..1350418 + 123 Protein_1320 LCP family protein -
OQH82_RS06870 (EfmGK923_13270) 1350831..1351937 + 1107 WP_002347028.1 FtsW/RodA/SpoVE family cell cycle protein -
OQH82_RS06875 (EfmGK923_13280) 1352029..1352784 + 756 WP_002303250.1 Regulatory protein MsrR VF
OQH82_RS06880 (EfmGK923_13290) 1352842..1354896 + 2055 WP_265169905.1 penicillin-binding transpeptidase domain-containing protein -
OQH82_RS06885 (EfmGK923_13300) 1354990..1356141 - 1152 WP_002295931.1 monovalent cation:proton antiporter-2 (CPA2) family protein -
OQH82_RS06890 (EfmGK923_13310) 1356295..1356825 - 531 WP_002288181.1 DUF308 domain-containing protein -
OQH82_RS06895 (EfmGK923_13320) 1356924..1357274 - 351 WP_002288180.1 DUF2200 domain-containing protein -
OQH82_RS06900 (EfmGK923_13330) 1357432..1358961 - 1530 WP_002288179.1 alkyl hydroperoxide reductase subunit F -
OQH82_RS06905 (EfmGK923_13340) 1358971..1359534 - 564 WP_002288178.1 alkyl hydroperoxide reductase subunit C -
OQH82_RS06910 (EfmGK923_13350) 1359678..1360340 - 663 WP_002288176.1 GntR family transcriptional regulator -
OQH82_RS06915 (EfmGK923_13360) 1360524..1362170 + 1647 WP_079158052.1 mannitol dehydrogenase family protein -
OQH82_RS06920 (EfmGK923_13370) 1362161..1363243 + 1083 WP_002303246.1 mannonate dehydratase -
OQH82_RS06925 1363351..1364905 - 1555 Protein_1332 helix-turn-helix domain-containing protein -
OQH82_RS06930 (EfmGK923_13400) 1365053..1366195 + 1143 Protein_1333 LPXTG cell wall anchor domain-containing protein -
OQH82_RS06935 (EfmGK923_13410) 1366321..1367400 - 1080 WP_002305261.1 AI-2E family transporter -
OQH82_RS06940 (EfmGK923_13420) 1367503..1367943 - 441 WP_002301992.1 MarR family transcriptional regulator -
OQH82_RS06945 (EfmGK923_13430) 1368000..1368410 - 411 WP_002288163.1 organic hydroperoxide resistance protein -
OQH82_RS06950 (EfmGK923_13440) 1368590..1369024 - 435 WP_002301993.1 VOC family protein -
OQH82_RS06955 (EfmGK923_13450) 1369124..1369972 - 849 WP_002303243.1 YitT family protein -
OQH82_RS06960 (EfmGK923_13460) 1370361..1372127 + 1767 WP_002301996.1 glycoside hydrolase family 13 protein -
OQH82_RS06965 (EfmGK923_13470) 1372229..1373488 + 1260 WP_265145860.1 extracellular solute-binding protein -
OQH82_RS06970 (EfmGK923_13480) 1373635..1374936 + 1302 WP_002288157.1 sugar ABC transporter permease -
OQH82_RS06975 (EfmGK923_13490) 1374939..1375790 + 852 WP_002288156.1 sugar ABC transporter permease -
OQH82_RS06980 (EfmGK923_13500) 1375803..1376618 + 816 WP_002295923.1 maltodextrose utilization protein MalA -
OQH82_RS06985 (EfmGK923_13510) 1376769..1377935 + 1167 WP_002295921.1 cyclopropane-fatty-acyl-phospholipid synthase family protein -
OQH82_RS06990 (EfmGK923_13520) 1378094..1379290 - 1197 Protein_1345 ISL3 family transposase ISEfa5 Transposase
OQH82_RS06995 (EfmGK923_13530) 1379686..1380333 + 648 WP_002295919.1 PepSY domain-containing protein -
OQH82_RS07000 (EfmGK923_13540) 1380417..1381361 + 945 WP_002295918.1 dihydroorotate oxidase -
OQH82_RS07005 (EfmGK923_13550) 1381496..1382947 + 1452 WP_002295917.1 amidase -
OQH82_RS07010 (EfmGK923_13560) 1382968..1383804 + 837 WP_002295916.1 transporter substrate-binding domain-containing protein -
OQH82_RS07015 (EfmGK923_13570) 1383804..1384463 + 660 WP_002347025.1 amino acid ABC transporter permease -
OQH82_RS07020 (EfmGK923_13580) 1384589..1385278 + 690 WP_002298443.1 hypothetical protein -
OQH82_RS07025 (EfmGK923_13590) 1385284..1386240 + 957 WP_002302623.1 sce7725 family protein -
OQH82_RS07030 (EfmGK923_13600) 1386284..1386796 + 513 WP_002302625.1 GNAT family N-acetyltransferase -
OQH82_RS07035 (EfmGK923_13610) 1387052..1387600 - 549 WP_002295911.1 AAA family ATPase -
OQH82_RS07040 (EfmGK923_13620) 1387689..1388948 - 1260 WP_265169906.1 nucleoside transporter C-terminal domain-containing protein -
OQH82_RS07045 (EfmGK923_13630) 1389106..1390614 - 1509 WP_002302627.1 DUF1846 domain-containing protein -
OQH82_RS07050 (EfmGK923_13640) 1390773..1390964 + 192 WP_002295907.1 hypothetical protein -
OQH82_RS07055 (EfmGK923_13650) 1391167..1392084 + 918 WP_002295906.1 hypothetical protein -
OQH82_RS07060 (EfmGK923_13660) 1392077..1393150 + 1074 WP_002295905.1 hypothetical protein -
OQH82_RS07065 (EfmGK923_13670) 1393298..1393816 + 519 WP_002295904.1 membrane protein -
OQH82_RS07070 (EfmGK923_13680) 1393797..1394189 + 393 WP_002302628.1 DUF4430 domain-containing protein -
OQH82_RS07075 (EfmGK923_13690) 1394265..1395200 + 936 WP_002295900.1 cation diffusion facilitator family transporter -
OQH82_RS07080 (EfmGK923_13700) 1395333..1396112 + 780 WP_002295898.1 AzlC family ABC transporter permease -
OQH82_RS07085 (EfmGK923_13710) 1396105..1396422 + 318 WP_002295896.1 AzlD domain-containing protein -
OQH82_RS07090 (EfmGK923_13720) 1396666..1398276 + 1611 WP_002286080.1 polysaccharide biosynthesis protein -
OQH82_RS07095 (EfmGK923_13730) 1398433..1399299 + 867 WP_265145862.1 DegV family protein -
OQH82_RS07100 (EfmGK923_13740) 1399353..1400033 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
OQH82_RS07105 (EfmGK923_13750) 1400089..1400346 + 258 Protein_1368 chromosome partitioning protein ParA -
OQH82_RS07110 (EfmGK923_13760) 1400438..1400653 + 216 WP_001835296.1 peptide-binding protein -
OQH82_RS07115 1400670..1400945 + 276 Protein_1370 antitoxin -
OQH82_RS07120 (EfmGK923_13770) 1400947..1401810 + 864 WP_001284311.1 zeta toxin family protein -
OQH82_RS07125 (EfmGK923_13780) 1402073..1402810 - 738 WP_001038796.1 rRNA adenine N-6-methyltransferase ARG
OQH82_RS07130 1402935..1403018 - 84 WP_031929417.1 23S rRNA methyltransferase attenuator leader peptide ErmL -
OQH82_RS07135 (EfmGK923_13790) 1403560..1404354 - 795 WP_001096887.1 Aminoglycoside 3'-phosphotransferase ARG
OQH82_RS07140 1404447..1404698 - 252 Protein_1375 GNAT family N-acetyltransferase -
OQH82_RS07145 (EfmGK923_13800) 1404944..1406240 + 1297 Protein_1376 ISL3 family transposase ISEfa11 Transposase
OQH82_RS07150 (EfmGK923_13820) 1406341..1407249 + 909 WP_002324522.1 IS982 family transposase ISEfm1 Transposase
OQH82_RS07155 1407273..1407485 - 213 Protein_1378 hypothetical protein -
OQH82_RS07160 (EfmGK923_13830) 1407486..1407821 - 336 Protein_1379 IS6 family transposase IS1216V Transposase
OQH82_RS07165 (EfmGK923_13840) 1408007..1408165 - 159 Protein_1380 IS6 family transposase IS1216V Transposase
OQH82_RS07170 (EfmGK923_13850) 1408315..1409907 + 1593 WP_033582318.1 MobP2 family relaxase -
OQH82_RS07175 (EfmGK923_13860) 1409928..1410263 + 336 WP_002302842.1 hypothetical protein -
OQH82_RS07180 (EfmGK923_13870) 1410409..1410603 + 195 WP_002302840.1 hypothetical protein -
OQH82_RS07185 1410739..1411986 - 1248 Protein_1384 IS110 family transposase -
OQH82_RS07190 1412675..1413012 + 338 Protein_1385 hypothetical protein -
OQH82_RS07195 1413595..1413837 + 243 Protein_1386 DNA primase -
OQH82_RS07200 (EfmGK923_13930) 1414084..1414767 + 684 WP_265169907.1 hypothetical protein -
OQH82_RS07205 (EfmGK923_13940) 1414828..1416288 + 1461 WP_002347152.1 toprim domain-containing protein -
OQH82_RS07210 (EfmGK923_13950) 1416299..1418503 + 2205 WP_002305772.1 type IA DNA topoisomerase -
OQH82_RS07215 (EfmGK923_13960) 1418519..1418668 + 150 WP_002303309.1 hypothetical protein -
OQH82_RS07220 (EfmGK923_13970) 1418744..1419337 + 594 WP_002303311.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
OQH82_RS07225 (EfmGK923_13980) 1419350..1420249 + 900 WP_002303312.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
OQH82_RS07230 (EfmGK923_13990) 1420252..1420737 + 486 WP_002303313.1 single-stranded DNA-binding protein -
OQH82_RS07235 1420878..1420982 - 105 WP_008274030.1 putative holin-like toxin -
OQH82_RS07240 (EfmGK923_14000) 1421156..1421416 + 261 WP_002295623.1 hypothetical protein -
OQH82_RS07245 (EfmGK923_14010) 1421853..1422059 + 207 WP_002347218.1 hypothetical protein -
OQH82_RS07250 (EfmGK923_14020) 1422059..1422310 + 252 WP_002296238.1 hypothetical protein -
OQH82_RS07255 (EfmGK923_14030) 1422325..1422762 + 438 WP_002300851.1 hypothetical protein -
OQH82_RS07260 (EfmGK923_14040) 1422755..1423462 + 708 WP_002303117.1 hypothetical protein -
OQH82_RS07265 (EfmGK923_14050) 1423627..1423827 + 201 WP_002347143.1 hypothetical protein -
OQH82_RS07270 (EfmGK923_14060) 1423843..1424022 + 180 WP_001120991.1 hypothetical protein -
OQH82_RS07275 (EfmGK923_14070) 1424153..1424422 + 270 WP_000388479.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
OQH82_RS07280 (EfmGK923_14080) 1424415..1424672 + 258 WP_000588503.1 Txe/YoeB family addiction module toxin Toxin Detail
OQH82_RS07285 (EfmGK923_14100) 1425309..1426133 + 825 WP_265169765.1 hypothetical protein -
OQH82_RS07290 (EfmGK923_14110) 1426298..1426912 - 615 WP_001261742.1 Tn3 family transposase TnpR_TnAs2 Transposase
OQH82_RS07295 (EfmGK923_14120) 1427150..1427572 + 423 WP_002303116.1 hypothetical protein -
OQH82_RS07300 1427716..1427808 - 93 Protein_1407 DDE-type integrase/transposase/recombinase -
OQH82_RS07305 (EfmGK923_14130) 1427993..1428577 + 585 WP_002299575.1 Tn3 family transposase TnBth3 Transposase
OQH82_RS07310 (EfmGK923_14140) 1428948..1429595 + 648 Protein_1409 type VI secretion protein ImpB -
OQH82_RS07315 (EfmGK923_14150) 1429652..1429912 - 261 Protein_1410 IS6 family transposase IS1216V Transposase
OQH82_RS07320 (EfmGK923_14160) 1430032..1430331 - 300 Protein_1411 IS6 family transposase IS1216E Transposase
OQH82_RS07325 (EfmGK923_14170) 1430415..1430915 + 501 WP_265145708.1 replication initiation protein -
OQH82_RS07330 (EfmGK923_14180) 1431081..1432274 - 1194 WP_021386846.1 Transposase from transposon Tn916 ; Integrase Integrase
OQH82_RS07335 (EfmGK923_14190) 1432353..1432559 - 207 WP_024725861.1 excisionase -
OQH82_RS07340 (EfmGK923_14200) 1432552..1433694 - 1143 WP_021382094.1 XRE family transcriptional regulator -
OQH82_RS07345 (EfmGK923_14210) 1434206..1434841 + 636 WP_008788621.1 helix-turn-helix transcriptional regulator -
OQH82_RS07350 1434995..1435072 + 78 Protein_1417 conjugal transfer protein -
OQH82_RS07355 1435317..1435391 + 75 Protein_1418 tetracycline resistance determinant leader peptide -
OQH82_RS07360 1435476..1436770 - 1295 Protein_1419 ISL3 family transposase ISEfa11 Transposase
OQH82_RS07365 (EfmGK923_14250) 1436970..1438889 + 1920 WP_231300330.1 Tetracycline resistance protein TetM from transposon TnFO1 VF
OQH82_RS07370 1439008..1439175 + 168 WP_000336323.1 cysteine-rich KTR domain-containing protein -
OQH82_RS07375 (EfmGK923_14260) 1439235..1439588 - 354 WP_001227347.1 helix-turn-helix transcriptional regulator -
OQH82_RS07380 1439826..1440505 + 680 Protein_1423 IS6 family transposase -
OQH82_RS07385 (EfmGK923_14290) 1440801..1441280 + 480 WP_002286073.1 DUF6530 family protein -
OQH82_RS07390 (EfmGK923_14300) 1441313..1443541 + 2229 WP_002286072.1 AAA family ATPase -
OQH82_RS07395 (EfmGK923_14310) 1443670..1445313 + 1644 WP_002286071.1 alpha-glucosidase -
OQH82_RS07400 (EfmGK923_14320) 1445386..1445931 - 546 WP_002286070.1 TIGR01440 family protein -
OQH82_RS07405 (EfmGK923_14330) 1445954..1446439 - 486 WP_002286069.1 ECF transporter S component -
OQH82_RS07410 (EfmGK923_14340) 1446429..1447241 - 813 WP_002286068.1 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase -
OQH82_RS07415 (EfmGK923_14350) 1447380..1448492 - 1113 Protein_1430 AMP-binding protein -
OQH82_RS07420 (EfmGK923_14360) 1448513..1449421 - 909 WP_002295743.1 IS982 family transposase ISEfm1 Transposase
OQH82_RS07425 (EfmGK923_14370) 1449534..1449959 - 426 Protein_1432 AMP-binding protein -
OQH82_RS07430 (EfmGK923_14380) 1450068..1451099 - 1032 WP_002286066.1 Tyrosine recombinase XerS ; Integrase Integrase
OQH82_RS07435 (EfmGK923_14390) 1451823..1452809 + 987 WP_002286065.1 DUF2382 domain-containing protein -
OQH82_RS07440 (EfmGK923_14400) 1452958..1454298 - 1341 WP_002286064.1 Sensor protein SrrB VF
OQH82_RS07445 (EfmGK923_14410) 1454303..1454977 - 675 WP_002286063.1 Response regulator MprA VF
OQH82_RS07450 (EfmGK923_14420) 1455199..1456272 + 1074 WP_002286061.1 ABC transporter permease -
OQH82_RS07455 (EfmGK923_14430) 1456278..1456964 + 687 WP_002286060.1 Putative hemin import ATP-binding protein HrtA VF
OQH82_RS07460 (EfmGK923_14440) 1456972..1457619 + 648 WP_002286057.1 TetR/AcrR family transcriptional regulator -
OQH82_RS07465 (EfmGK923_14450) 1457692..1459083 - 1392 WP_002286056.1 helix-turn-helix domain-containing protein -
OQH82_RS07470 (EfmGK923_14460) 1459340..1462729 + 3390 WP_002286055.1 hypothetical protein VF
OQH82_RS07475 (EfmGK923_14470) 1462732..1464153 + 1422 WP_002286054.1 hypothetical protein VF
OQH82_RS07480 (EfmGK923_14480) 1464150..1466027 + 1878 WP_002286053.1 hypothetical protein VF
OQH82_RS07485 (EfmGK923_14490) 1466119..1466961 + 843 WP_002286052.1 hypothetical protein VF
OQH82_RS07490 (EfmGK923_14500) 1467113..1467988 - 876 WP_002286051.1 MurR/RpiR family transcriptional regulator -
OQH82_RS07495 (EfmGK923_14510) 1468195..1469226 + 1032 WP_002286050.1 Gfo/Idh/MocA family oxidoreductase -
OQH82_RS07500 (EfmGK923_14520) 1469315..1469620 + 306 WP_002286049.1 hypothetical protein -
OQH82_RS07505 (EfmGK923_14530) 1469799..1471814 + 2016 WP_002286048.1 PTS sugar transporter subunit IIA -
OQH82_RS07510 (EfmGK923_14540) 1471816..1472100 + 285 WP_002286047.1 PTS sugar transporter subunit IIB -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance