MGE detailed information
MGE type: Conjugative plasmid MGE length: 133781 bp
Accession: NZ_AP024796 Location: 1..133781 Organism: Klebsiella pneumoniae strain TUM12140 Replicon: plasmid IncN-R
Accession: NZ_AP024796 Location: 1..133781 Organism: Klebsiella pneumoniae strain TUM12140 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J94_RS26375 (TUM12140_50660) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6J94_RS26380 | 1372..1614 | + | 243 | WP_228740933.1 | RepB family plasmid replication initiator protein | - |
| K6J94_RS26385 (TUM12140_50670) | 2299..2598 | + | 300 | Protein_2 | IS66 family transposase ISEc22 | Transposase |
| K6J94_RS26390 (TUM12140_50680) | 2670..5321 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J94_RS27380 (TUM12140_50700) | 5740..6006 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J94_RS26395 | 5938..6623 | + | 686 | Protein_5 | IS3 family transposase ISEc14 | Transposase |
| K6J94_RS26400 (TUM12140_50720) | 7296..8804 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J94_RS26405 | 8885..9064 | + | 180 | Protein_7 | DDE-type integrase/transposase/recombinase | - |
| K6J94_RS26410 (TUM12140_50730) | 9346..10422 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J94_RS26415 | 10439..10715 | + | 277 | Protein_9 | IS3 family transposase | - |
| K6J94_RS26420 | 10830..11006 | + | 177 | Protein_10 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J94_RS26425 (TUM12140_50740) | 11021..11857 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J94_RS26430 (TUM12140_50750) | 11922..12320 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J94_RS26435 (TUM12140_50760) | 12364..13473 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J94_RS26440 (TUM12140_50770) | 13508..13783 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J94_RS26450 (TUM12140_50800) | 15205..15774 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J94_RS26455 (TUM12140_50810) | 16014..17228 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J94_RS26460 (TUM12140_50820) | 17262..18695 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J94_RS26465 (TUM12140_50830) | 18794..19066 | + | 273 | Protein_19 | IS1 family transposase IS1X2 | Transposase |
| K6J94_RS26470 (TUM12140_50840) | 19077..19283 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J94_RS26475 (TUM12140_50850) | 19288..19929 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J94_RS26480 (TUM12140_50860) | 19985..20296 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J94_RS26485 (TUM12140_50870) | 20332..20646 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J94_RS26490 (TUM12140_50880) | 20643..20987 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J94_RS26495 (TUM12140_50890) | 21003..21308 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J94_RS26500 (TUM12140_50900) | 21417..22154 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J94_RS26505 (TUM12140_50910) | 22163..22444 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J94_RS26510 (TUM12140_50920) | 22454..22747 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J94_RS26515 (TUM12140_50930) | 22797..23114 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J94_RS26520 (TUM12140_50940) | 23114..25714 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J94_RS26525 (TUM12140_50950) | 25732..26445 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J94_RS26530 (TUM12140_50960) | 26453..26680 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J94_RS26535 (TUM12140_50970) | 26696..27736 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J94_RS26540 (TUM12140_50980) | 27955..28653 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J94_RS26545 (TUM12140_50990) | 28664..29548 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J94_RS26550 (TUM12140_51000) | 29548..30708 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J94_RS26555 (TUM12140_51010) | 30750..31745 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J94_RS26560 (TUM12140_51020) | 31745..32011 | + | 267 | Protein_38 | hypothetical protein | VF |
| K6J94_RS26565 (TUM12140_51030) | 32217..32348 | - | 132 | Protein_39 | hypothetical protein | VF |
| K6J94_RS26570 (TUM12140_51040) | 32405..33397 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J94_RS26575 | 33446..33601 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J94_RS26580 (TUM12140_51050) | 33896..35611 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J94_RS26585 (TUM12140_51060) | 35721..38750 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J94_RS26590 (TUM12140_51070) | 38857..39882 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J94_RS26595 (TUM12140_51080) | 39879..40658 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J94_RS26600 (TUM12140_51090) | 40946..41827 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J94_RS26605 (TUM12140_51100) | 42077..43396 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J94_RS26610 | 43750..43923 | - | 174 | Protein_48 | replication initiation protein | - |
| K6J94_RS26620 (TUM12140_51130) | 44782..46269 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6J94_RS26625 (TUM12140_51140) | 46675..47106 | + | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J94_RS26630 (TUM12140_51150) | 47106..48377 | + | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J94_RS26635 (TUM12140_51160) | 48459..49433 | - | 975 | WP_000064119.1 | ParB family protein | - |
| K6J94_RS26640 (TUM12140_51170) | 49433..50638 | - | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J94_RS26645 (TUM12140_51180) | 51053..51322 | + | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J94_RS26650 (TUM12140_51190) | 51499..52365 | - | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J94_RS26655 | 52895..52999 | + | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J94_RS27385 (TUM12140_51200) | 53128..53226 | + | 99 | Protein_58 | hypothetical protein | - |
| K6J94_RS26660 (TUM12140_51210) | 53357..53527 | - | 171 | Protein_59 | serine hydrolase | - |
| K6J94_RS26665 (TUM12140_51220) | 53582..54286 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J94_RS26670 (TUM12140_51230) | 54352..54567 | - | 216 | Protein_61 | IS6 family transposase IS15 | Transposase |
| K6J94_RS26675 (TUM12140_51240) | 54637..55191 | - | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J94_RS26680 (TUM12140_51250) | 55425..55982 | - | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J94_RS26685 (TUM12140_51270) | 56144..59149 | + | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J94_RS27390 (TUM12140_51280) | 59184..59363 | + | 180 | Protein_65 | hypothetical protein | - |
| K6J94_RS26690 (TUM12140_51290) | 59421..60197 | - | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J94_RS26695 (TUM12140_51300) | 60194..60937 | - | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J94_RS26700 (TUM12140_51310) | 60988..61338 | - | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J94_RS26705 | 61482..61943 | - | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J94_RS26710 (TUM12140_51320) | 61900..62130 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J94_RS26715 (TUM12140_51330) | 62127..62543 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J94_RS26720 (TUM12140_51340) | 62617..63306 | + | 690 | Protein_72 | AAA family ATPase | - |
| K6J94_RS26725 | 63361..64058 | + | 698 | WP_223174630.1 | IS1 family transposase ISKpn14 | Transposase |
| K6J94_RS26730 | 64074..64184 | + | 111 | Protein_74 | mercuric transport protein periplasmic component | - |
| K6J94_RS26735 (TUM12140_51370) | 64220..64642 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J94_RS26740 (TUM12140_51380) | 64694..66388 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J94_RS26745 (TUM12140_51390) | 66406..66768 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J94_RS26750 (TUM12140_51400) | 66765..67001 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J94_RS26755 (TUM12140_51410) | 67037..67705 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J94_RS26760 (TUM12140_51420) | 67780..69030 | + | 1251 | Protein_80 | transposase | - |
| K6J94_RS26765 (TUM12140_51430) | 69095..69466 | + | 372 | Protein_81 | IS6 family transposase IS15DII | Transposase |
| K6J94_RS26770 (TUM12140_51440) | 69615..70480 | - | 866 | Protein_82 | Beta-lactamase TEM | ARG |
| K6J94_RS26775 (TUM12140_51450) | 70663..70980 | - | 318 | Protein_83 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J94_RS26780 | 71180..72006 | - | 827 | Protein_84 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J94_RS26785 | 72066..72176 | - | 111 | Protein_85 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J94_RS26790 (TUM12140_51480) | 72226..72929 | - | 704 | Protein_86 | IS6 family transposase IS15DII | Transposase |
| K6J94_RS26795 (TUM12140_51490) | 73002..75899 | + | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J94_RS26800 (TUM12140_51500) | 75988..76608 | + | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J94_RS26805 | 76707..77117 | + | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J94_RS26810 (TUM12140_51510) | 77774..78133 | - | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J94_RS26815 (TUM12140_51520) | 78305..78535 | - | 231 | Protein_91 | IS5 family transposase ISAeme7 | Transposase |
| K6J94_RS26820 (TUM12140_51530) | 78637..79752 | + | 1116 | WP_004163961.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J94_RS26825 | 80093..81411 | + | 1319 | Protein_93 | IS1182-like element ISKpn6 family transposase | - |
| K6J94_RS26830 (TUM12140_51560) | 81661..82542 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J94_RS26835 (TUM12140_51570) | 82830..83609 | - | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J94_RS26840 (TUM12140_51580) | 83606..84629 | - | 1024 | Protein_96 | IS21 family transposase ISKpn7 | Transposase |
| K6J94_RS26845 | 84736..87772 | - | 3037 | Protein_97 | Tn3 family transposase ISPsy42 | Transposase |
| K6J94_RS26850 (TUM12140_51620) | 87882..89599 | + | 1718 | Protein_98 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J94_RS26855 (TUM12140_51630) | 91195..92163 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
| K6J94_RS26860 (TUM12140_51640) | 92302..92688 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| K6J94_RS26865 (TUM12140_51650) | 93270..93503 | + | 234 | Protein_101 | transposase | - |
| K6J94_RS26870 (TUM12140_51660) | 93536..96502 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J94_RS26875 (TUM12140_51670) | 96506..97066 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J94_RS26880 (TUM12140_51680) | 97242..97592 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J94_RS26885 (TUM12140_51700) | 97795..98808 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J94_RS26890 (TUM12140_51710) | 98975..99817 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J94_RS26895 (TUM12140_51720) | 99913..100521 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J94_RS26900 (TUM12140_51730) | 100579..101417 | + | 839 | Protein_108 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J94_RS26905 | 101632..102891 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J94_RS26910 (TUM12140_51750) | 102984..103822 | + | 839 | Protein_110 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J94_RS26915 (TUM12140_51760) | 103945..104277 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J94_RS26920 (TUM12140_51770) | 104524..105156 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J94_RS26925 (TUM12140_51780) | 105471..106451 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J94_RS26930 (TUM12140_51790) | 106557..107261 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J94_RS26935 (TUM12140_51800) | 107375..108151 | + | 777 | WP_001199192.1 | hypothetical protein | ARG |
| K6J94_RS26940 (TUM12140_51820) | 108380..109405 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J94_RS26945 | 109480..109767 | + | 288 | Protein_117 | AAC(3) family N-acetyltransferase | - |
| K6J94_RS26950 (TUM12140_51830) | 109827..110579 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J94_RS26955 (TUM12140_51840) | 110641..111522 | + | 882 | Protein_119 | Tn3 family transposase | - |
| K6J94_RS26960 | 111685..111768 | - | 84 | Protein_120 | SOS response-associated peptidase | - |
| K6J94_RS26965 (TUM12140_51850) | 112633..112908 | + | 276 | Protein_121 | Phospholipase D | VF |
| K6J94_RS26970 (TUM12140_51860) | 113081..113395 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J94_RS26975 (TUM12140_51870) | 113650..114006 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J94_RS26980 (TUM12140_51880) | 113996..114397 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J94_RS26985 (TUM12140_51890) | 114394..114684 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J94_RS26990 (TUM12140_51900) | 114748..115146 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J94_RS26995 (TUM12140_51910) | 115146..118382 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J94_RS27000 (TUM12140_51920) | 118382..119911 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J94_RS27005 (TUM12140_51930) | 119913..120329 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J94_RS27010 (TUM12140_51940) | 120886..121272 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6J94_RS27015 (TUM12140_51950) | 121281..121997 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J94_RS27020 (TUM12140_51960) | 121999..122367 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6J94_RS27025 (TUM12140_51970) | 122568..122906 | + | 339 | WP_228740928.1 | hypothetical protein | - |
| K6J94_RS27480 | 123376..123554 | - | 179 | Protein_134 | protein CcgAI | - |
| K6J94_RS27030 (TUM12140_51980) | 124390..124899 | - | 510 | WP_012561131.1 | antirestriction protein ArdA | - |
| K6J94_RS27035 (TUM12140_51990) | 126248..126580 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6J94_RS27485 | 126789..127073 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6J94_RS27050 (TUM12140_52010) | 127499..127795 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J94_RS27055 (TUM12140_52030) | 128679..128918 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J94_RS27060 (TUM12140_52040) | 128928..129332 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J94_RS27065 (TUM12140_52050) | 129390..129815 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J94_RS27070 (TUM12140_52060) | 130231..130671 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J94_RS27075 (TUM12140_52070) | 130659..131924 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J94_RS27080 (TUM12140_52080) | 132075..132866 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J94_RS27085 (TUM12140_52090) | 132881..133222 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|