MGE detailed information
MGE type: Conjugative plasmid MGE length: 133170 bp
Accession: NZ_AP024793 Location: 1..133170 Organism: Klebsiella pneumoniae strain TUM12139 Replicon: plasmid IncN-R
Accession: NZ_AP024793 Location: 1..133170 Organism: Klebsiella pneumoniae strain TUM12139 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J92_RS26365 (TUM12139_50690) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6J92_RS26370 (TUM12139_50700) | 1701..2000 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6J92_RS26375 (TUM12139_50710) | 2072..4723 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J92_RS27370 (TUM12139_50730) | 5142..5408 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J92_RS26380 | 5340..6025 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6J92_RS26385 (TUM12139_50750) | 6698..8206 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J92_RS26390 | 8287..8466 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6J92_RS26395 (TUM12139_50760) | 8748..9824 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J92_RS26400 | 9841..10117 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6J92_RS26405 | 10232..10408 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J92_RS26410 (TUM12139_50770) | 10423..11259 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J92_RS26415 (TUM12139_50780) | 11324..11722 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J92_RS26420 (TUM12139_50790) | 11766..12875 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J92_RS26425 (TUM12139_50800) | 12910..13185 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J92_RS26435 (TUM12139_50830) | 14607..15176 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J92_RS26440 (TUM12139_50840) | 15416..16630 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J92_RS26445 (TUM12139_50850) | 16664..18097 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J92_RS26450 (TUM12139_50860) | 18196..18468 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6J92_RS26455 (TUM12139_50870) | 18479..18685 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J92_RS26460 (TUM12139_50880) | 18690..19331 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J92_RS26465 (TUM12139_50890) | 19387..19698 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J92_RS26470 (TUM12139_50900) | 19734..20048 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J92_RS26475 (TUM12139_50910) | 20045..20389 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J92_RS26480 (TUM12139_50920) | 20405..20710 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J92_RS26485 (TUM12139_50930) | 20819..21556 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J92_RS26490 (TUM12139_50940) | 21565..21846 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J92_RS26495 (TUM12139_50950) | 21856..22149 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J92_RS26500 (TUM12139_50960) | 22199..22516 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J92_RS26505 (TUM12139_50970) | 22516..25116 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J92_RS26510 (TUM12139_50980) | 25134..25847 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J92_RS26515 (TUM12139_50990) | 25855..26082 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J92_RS26520 (TUM12139_51000) | 26098..27138 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J92_RS26525 (TUM12139_51010) | 27357..28055 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J92_RS26530 (TUM12139_51020) | 28066..28950 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J92_RS26535 (TUM12139_51030) | 28950..30110 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J92_RS26540 (TUM12139_51040) | 30152..31147 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J92_RS26545 (TUM12139_51050) | 31147..31413 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6J92_RS26550 (TUM12139_51060) | 31619..31750 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6J92_RS26555 (TUM12139_51070) | 31807..32799 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J92_RS26560 | 32848..33003 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J92_RS26565 (TUM12139_51080) | 33298..35013 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J92_RS26570 (TUM12139_51090) | 35123..38152 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J92_RS26575 (TUM12139_51100) | 38259..39284 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J92_RS26580 (TUM12139_51110) | 39281..40060 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J92_RS26585 (TUM12139_51120) | 40348..41229 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J92_RS26590 (TUM12139_51130) | 41479..42798 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J92_RS26595 (TUM12139_51140) | 43075..44259 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J92_RS26600 (TUM12139_51150) | 44361..44591 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6J92_RS26605 (TUM12139_51160) | 44763..45122 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J92_RS26610 | 45779..46189 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J92_RS26615 (TUM12139_51170) | 46288..46908 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J92_RS26620 (TUM12139_51180) | 46997..49894 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J92_RS26625 (TUM12139_51190) | 49967..50671 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J92_RS26630 | 50721..50831 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J92_RS26635 | 50891..51715 | + | 825 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J92_RS26640 (TUM12139_51220) | 51915..52232 | + | 318 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J92_RS26645 (TUM12139_51230) | 52415..53275 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6J92_RS26650 (TUM12139_51240) | 53425..53796 | - | 372 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6J92_RS26655 (TUM12139_51250) | 53861..55111 | - | 1251 | Protein_59 | transposase | - |
| K6J92_RS26660 (TUM12139_51260) | 55186..55854 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J92_RS26665 (TUM12139_51270) | 55890..56126 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J92_RS26670 (TUM12139_51280) | 56123..56485 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J92_RS26675 (TUM12139_51290) | 56503..58197 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J92_RS26680 (TUM12139_51300) | 58249..58671 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J92_RS26685 | 58707..58817 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6J92_RS26695 (TUM12139_51330) | 59585..60274 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6J92_RS26700 (TUM12139_51340) | 60348..60764 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J92_RS26705 (TUM12139_51350) | 60761..60991 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J92_RS26710 | 60948..61409 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J92_RS26715 (TUM12139_51360) | 61553..61903 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J92_RS26720 (TUM12139_51370) | 61954..62697 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J92_RS26725 (TUM12139_51380) | 62694..63470 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J92_RS27375 (TUM12139_51390) | 63528..63707 | - | 180 | Protein_74 | hypothetical protein | - |
| K6J92_RS26730 (TUM12139_51400) | 63742..66747 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J92_RS26735 (TUM12139_51420) | 66909..67466 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J92_RS26740 (TUM12139_51430) | 67700..68254 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J92_RS26745 (TUM12139_51440) | 68324..68539 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6J92_RS26750 (TUM12139_51450) | 68605..69309 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J92_RS26755 (TUM12139_51460) | 69364..69534 | + | 171 | Protein_80 | serine hydrolase | - |
| K6J92_RS27380 (TUM12139_51470) | 69665..69763 | - | 99 | Protein_81 | hypothetical protein | - |
| K6J92_RS26760 | 69892..69996 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J92_RS26765 (TUM12139_51480) | 70526..71392 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J92_RS26770 (TUM12139_51490) | 71569..71838 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J92_RS26775 (TUM12139_51500) | 72253..73458 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J92_RS26780 (TUM12139_51510) | 73458..74432 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J92_RS26785 (TUM12139_51520) | 74514..75785 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J92_RS26790 (TUM12139_51530) | 75785..76216 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J92_RS26795 (TUM12139_51540) | 76622..78109 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6J92_RS26800 | 78260..78956 | + | 697 | WP_020277971.1 | IS1 family transposase IS1X3 | Transposase |
| K6J92_RS26805 | 78966..79139 | + | 174 | Protein_91 | replication initiation protein | - |
| K6J92_RS26810 (TUM12139_51570) | 79491..80810 | + | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J92_RS26815 | 81060..81940 | - | 881 | Protein_93 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J92_RS26820 (TUM12139_51600) | 82228..83007 | - | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J92_RS26825 (TUM12139_51610) | 83004..84028 | - | 1025 | Protein_95 | IS21 family transposase ISKpn7 | Transposase |
| K6J92_RS26830 | 84135..87166 | - | 3032 | Protein_96 | Tn3 family transposase ISPsy42 | Transposase |
| K6J92_RS26835 (TUM12139_51640) | 87276..88994 | + | 1719 | WP_221270907.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J92_RS26840 (TUM12139_51650) | 90589..91557 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
| K6J92_RS27475 (TUM12139_51660) | 91696..91881 | - | 186 | WP_232585769.1 | StbA | - |
| K6J92_RS26850 (TUM12139_51670) | 92663..92896 | + | 234 | Protein_100 | IS5 family transposase ISPan1 | Transposase |
| K6J92_RS26855 (TUM12139_51680) | 92929..95895 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J92_RS26860 (TUM12139_51690) | 95899..96459 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J92_RS26865 (TUM12139_51700) | 96635..96985 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J92_RS26870 (TUM12139_51710) | 97188..98201 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J92_RS26875 (TUM12139_51720) | 98368..99210 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J92_RS26880 (TUM12139_51730) | 99306..99914 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J92_RS26885 (TUM12139_51740) | 99972..100810 | + | 839 | Protein_107 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J92_RS26890 | 101025..102284 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J92_RS26895 (TUM12139_51760) | 102377..103215 | + | 839 | Protein_109 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J92_RS26900 (TUM12139_51770) | 103338..103670 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J92_RS26905 (TUM12139_51780) | 103917..104549 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J92_RS26910 (TUM12139_51790) | 104864..105844 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J92_RS26915 (TUM12139_51800) | 105950..106654 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J92_RS26920 (TUM12139_51810) | 106768..107544 | + | 777 | WP_001199192.1 | hypothetical protein | ARG |
| K6J92_RS26925 (TUM12139_51830) | 107773..108798 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J92_RS26930 | 108873..109160 | + | 288 | Protein_116 | AAC(3) family N-acetyltransferase | - |
| K6J92_RS26935 (TUM12139_51840) | 109220..109972 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J92_RS26940 (TUM12139_51850) | 110034..110915 | + | 882 | Protein_118 | Tn3 family transposase | - |
| K6J92_RS26945 | 111077..111160 | - | 84 | Protein_119 | SOS response-associated peptidase | - |
| K6J92_RS26950 (TUM12139_51860) | 112026..112301 | + | 276 | Protein_120 | Phospholipase D | VF |
| K6J92_RS26955 (TUM12139_51870) | 112474..112788 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J92_RS26960 (TUM12139_51880) | 113043..113399 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J92_RS26965 (TUM12139_51890) | 113389..113790 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J92_RS26970 (TUM12139_51900) | 113787..114077 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J92_RS26975 (TUM12139_51910) | 114141..114539 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J92_RS26980 (TUM12139_51920) | 114539..117775 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J92_RS26985 (TUM12139_51930) | 117775..119304 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J92_RS26990 (TUM12139_51940) | 119306..119722 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J92_RS26995 (TUM12139_51950) | 120279..120665 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6J92_RS27000 (TUM12139_51960) | 120674..121390 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J92_RS27005 (TUM12139_51970) | 121392..121760 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6J92_RS27010 (TUM12139_51980) | 121961..122305 | + | 345 | WP_012561137.1 | hypothetical protein | - |
| K6J92_RS27015 (TUM12139_51990) | 122767..122946 | - | 180 | WP_012561134.1 | protein CcgAI | - |
| K6J92_RS27020 (TUM12139_52000) | 123777..124286 | - | 510 | WP_012561131.1 | antirestriction protein ArdA | - |
| K6J92_RS27025 (TUM12139_52010) | 125638..125970 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6J92_RS27030 (TUM12139_52020) | 126179..126463 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6J92_RS27390 | 126532..126732 | - | 201 | WP_020319888.1 | hypothetical protein | - |
| K6J92_RS27040 (TUM12139_52040) | 126888..127184 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J92_RS27045 (TUM12139_52050) | 128068..128307 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J92_RS27050 (TUM12139_52060) | 128317..128721 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J92_RS27055 (TUM12139_52070) | 128779..129204 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J92_RS27060 (TUM12139_52080) | 129620..130060 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J92_RS27065 (TUM12139_52090) | 130048..131313 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J92_RS27070 (TUM12139_52100) | 131464..132255 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J92_RS27075 (TUM12139_52110) | 132270..132611 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|