MGE detailed information
MGE type: Conjugative plasmid MGE length: 123780 bp
Accession: NZ_AP024790 Location: 1..123780 Organism: Klebsiella pneumoniae strain TUM12138 Replicon: plasmid IncN-R
Accession: NZ_AP024790 Location: 1..123780 Organism: Klebsiella pneumoniae strain TUM12138 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6K06_RS27080 (TUM12138_52290) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6K06_RS27085 (TUM12138_52300) | 2218..2517 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6K06_RS27090 (TUM12138_52310) | 2589..5240 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6K06_RS28035 (TUM12138_52330) | 5659..5925 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6K06_RS27095 | 5857..6542 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6K06_RS27100 (TUM12138_52350) | 7215..8723 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6K06_RS27105 | 8804..8983 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6K06_RS27110 (TUM12138_52360) | 9265..10341 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6K06_RS27115 | 10358..10634 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6K06_RS27120 | 10749..10925 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6K06_RS27125 (TUM12138_52370) | 10940..11776 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6K06_RS27130 (TUM12138_52380) | 11841..12239 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6K06_RS27135 (TUM12138_52390) | 12283..13392 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6K06_RS27140 (TUM12138_52400) | 13427..13702 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6K06_RS27150 (TUM12138_52430) | 15124..15693 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6K06_RS27155 (TUM12138_52440) | 15933..17147 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6K06_RS27160 (TUM12138_52450) | 17181..18614 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6K06_RS27165 (TUM12138_52460) | 18713..18985 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6K06_RS27170 (TUM12138_52470) | 18996..19202 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6K06_RS27175 (TUM12138_52480) | 19207..19848 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6K06_RS27180 (TUM12138_52490) | 19904..20215 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6K06_RS27185 (TUM12138_52500) | 20251..20565 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6K06_RS27190 (TUM12138_52510) | 20562..20906 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6K06_RS27195 (TUM12138_52520) | 20922..21227 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6K06_RS27200 (TUM12138_52530) | 21336..22073 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6K06_RS27205 (TUM12138_52540) | 22082..22363 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6K06_RS27210 (TUM12138_52550) | 22373..22666 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6K06_RS27215 (TUM12138_52560) | 22716..23033 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6K06_RS27220 (TUM12138_52570) | 23033..25633 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6K06_RS27225 (TUM12138_52580) | 25651..26364 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6K06_RS27230 (TUM12138_52590) | 26372..26599 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6K06_RS27235 (TUM12138_52600) | 26615..27655 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6K06_RS27240 (TUM12138_52610) | 27874..28572 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6K06_RS27245 (TUM12138_52620) | 28583..29467 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6K06_RS27250 (TUM12138_52630) | 29467..30627 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6K06_RS27255 (TUM12138_52640) | 30669..31664 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6K06_RS27260 (TUM12138_52650) | 31664..31930 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6K06_RS27265 (TUM12138_52660) | 32136..32267 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6K06_RS27270 (TUM12138_52670) | 32324..33316 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6K06_RS27275 | 33365..33520 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6K06_RS27280 (TUM12138_52680) | 33815..35530 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6K06_RS27285 (TUM12138_52690) | 35640..38669 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6K06_RS27290 (TUM12138_52700) | 38776..39801 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6K06_RS27295 (TUM12138_52710) | 39798..40577 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6K06_RS27300 (TUM12138_52720) | 40865..41746 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6K06_RS27305 (TUM12138_52730) | 41996..43315 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6K06_RS27310 (TUM12138_52740) | 43592..44776 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6K06_RS27315 (TUM12138_52750) | 44878..45108 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6K06_RS27320 (TUM12138_52760) | 45280..45639 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6K06_RS27325 | 46296..46706 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6K06_RS27330 (TUM12138_52770) | 46805..47425 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6K06_RS27335 (TUM12138_52780) | 47514..50411 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6K06_RS27340 (TUM12138_52790) | 50484..51188 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6K06_RS27345 | 51238..51348 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6K06_RS27350 | 51408..52232 | + | 825 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6K06_RS27355 (TUM12138_52820) | 52432..52749 | + | 318 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6K06_RS27360 (TUM12138_52830) | 52932..53792 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6K06_RS27365 (TUM12138_52840) | 53942..54313 | - | 372 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6K06_RS27370 (TUM12138_52850) | 54378..55628 | - | 1251 | Protein_59 | transposase | - |
| K6K06_RS27375 (TUM12138_52860) | 55703..56371 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6K06_RS27380 (TUM12138_52870) | 56407..56643 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6K06_RS27385 (TUM12138_52880) | 56640..57002 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6K06_RS27390 (TUM12138_52890) | 57020..58714 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6K06_RS27395 (TUM12138_52900) | 58766..59188 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6K06_RS27400 | 59224..59334 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6K06_RS27410 (TUM12138_52930) | 60102..60791 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6K06_RS27415 (TUM12138_52940) | 60865..61281 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6K06_RS27420 (TUM12138_52950) | 61278..61508 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6K06_RS27425 | 61465..61926 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6K06_RS27430 (TUM12138_52960) | 62070..62420 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6K06_RS27435 (TUM12138_52970) | 62471..63214 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6K06_RS27440 (TUM12138_52980) | 63211..63987 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6K06_RS28040 (TUM12138_52990) | 64045..64224 | - | 180 | Protein_74 | hypothetical protein | - |
| K6K06_RS27445 (TUM12138_53000) | 64259..67264 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6K06_RS27450 (TUM12138_53020) | 67426..67983 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6K06_RS27455 (TUM12138_53030) | 68217..68771 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6K06_RS27460 (TUM12138_53040) | 68841..69056 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6K06_RS27465 (TUM12138_53050) | 69122..69826 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6K06_RS27470 (TUM12138_53060) | 69881..70051 | + | 171 | Protein_80 | serine hydrolase | - |
| K6K06_RS28045 (TUM12138_53070) | 70182..70280 | - | 99 | Protein_81 | hypothetical protein | - |
| K6K06_RS27475 | 70409..70513 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6K06_RS27480 (TUM12138_53080) | 71043..71909 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6K06_RS27485 (TUM12138_53090) | 72086..72355 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6K06_RS27490 (TUM12138_53100) | 72770..73975 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6K06_RS27495 (TUM12138_53110) | 73975..74949 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6K06_RS27500 (TUM12138_53120) | 75031..76302 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6K06_RS27505 (TUM12138_53130) | 76302..76733 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6K06_RS27510 (TUM12138_53140) | 77139..78626 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6K06_RS27515 | 78777..79473 | + | 697 | WP_020277971.1 | IS1 family transposase IS1X3 | Transposase |
| K6K06_RS27520 | 79483..79791 | + | 309 | Protein_91 | replication initiation protein | - |
| K6K06_RS27525 (TUM12138_53170) | 81193..82161 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
| K6K06_RS27530 (TUM12138_53180) | 82302..82688 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| K6K06_RS27535 (TUM12138_53190) | 83275..83508 | + | 234 | Protein_94 | IS5 family transposase ISPan1 | Transposase |
| K6K06_RS27540 (TUM12138_53200) | 83541..86507 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6K06_RS27545 (TUM12138_53210) | 86511..87071 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6K06_RS27550 (TUM12138_53220) | 87247..87597 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6K06_RS27555 (TUM12138_53230) | 87800..88813 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6K06_RS27560 (TUM12138_53240) | 88980..89822 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6K06_RS27565 (TUM12138_53250) | 89918..90526 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6K06_RS27570 (TUM12138_53260) | 90584..91422 | + | 839 | Protein_101 | Streptomycin 3''-adenylyltransferase | ARG |
| K6K06_RS27575 | 91637..92896 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6K06_RS27580 (TUM12138_53280) | 92989..93827 | + | 839 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6K06_RS27585 (TUM12138_53290) | 93950..94282 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6K06_RS27590 (TUM12138_53300) | 94529..95161 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6K06_RS27595 (TUM12138_53310) | 95476..96456 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6K06_RS27600 (TUM12138_53320) | 96562..97266 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6K06_RS27605 (TUM12138_53330) | 97380..98156 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6K06_RS27610 (TUM12138_53350) | 98385..99410 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6K06_RS27615 | 99485..99772 | + | 288 | Protein_110 | AAC(3) family N-acetyltransferase | - |
| K6K06_RS27620 (TUM12138_53360) | 99832..100584 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6K06_RS27625 (TUM12138_53370) | 100646..101527 | + | 882 | Protein_112 | Tn3 family transposase | - |
| K6K06_RS27630 | 101690..101773 | - | 84 | Protein_113 | SOS response-associated peptidase | - |
| K6K06_RS27635 (TUM12138_53380) | 102641..102916 | + | 276 | Protein_114 | Phospholipase D | VF |
| K6K06_RS27640 (TUM12138_53390) | 103089..103403 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6K06_RS27645 (TUM12138_53400) | 103658..104014 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6K06_RS27650 (TUM12138_53410) | 104004..104405 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6K06_RS27655 (TUM12138_53420) | 104402..104692 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6K06_RS27660 (TUM12138_53430) | 104756..105154 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6K06_RS27665 (TUM12138_53440) | 105154..108390 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6K06_RS27670 (TUM12138_53450) | 108390..109919 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6K06_RS27675 (TUM12138_53460) | 109921..110337 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6K06_RS27680 (TUM12138_53470) | 110894..111280 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6K06_RS27685 (TUM12138_53480) | 111289..112005 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6K06_RS27690 (TUM12138_53490) | 112007..112375 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6K06_RS27695 (TUM12138_53500) | 112576..112920 | + | 345 | WP_012561137.1 | hypothetical protein | - |
| K6K06_RS27700 (TUM12138_53510) | 113382..113561 | - | 180 | WP_012561134.1 | protein CcgAI | - |
| K6K06_RS27705 (TUM12138_53520) | 114388..114897 | - | 510 | WP_012561131.1 | antirestriction protein ArdA | - |
| K6K06_RS27710 (TUM12138_53530) | 116247..116579 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6K06_RS27715 (TUM12138_53540) | 116789..117073 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6K06_RS28050 | 117142..117342 | - | 201 | WP_020319888.1 | hypothetical protein | - |
| K6K06_RS27725 (TUM12138_53560) | 117498..117794 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6K06_RS27730 (TUM12138_53570) | 118678..118917 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6K06_RS27735 (TUM12138_53580) | 118927..119331 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6K06_RS27740 (TUM12138_53590) | 119389..119814 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6K06_RS27745 (TUM12138_53600) | 120230..120670 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6K06_RS27750 (TUM12138_53610) | 120658..121923 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6K06_RS27755 (TUM12138_53620) | 122074..122865 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6K06_RS27760 (TUM12138_53630) | 122880..123221 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|