MGE detailed information
MGE type: Conjugative plasmid MGE length: 128491 bp
Accession: NZ_AP024786 Location: 1..128491 Organism: Klebsiella pneumoniae strain TUM12137 Replicon: plasmid IncN-R
Accession: NZ_AP024786 Location: 1..128491 Organism: Klebsiella pneumoniae strain TUM12137 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6K11_RS27075 (TUM12137_52270) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6K11_RS27080 (TUM12137_52280) | 1812..2111 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6K11_RS27085 (TUM12137_52290) | 2183..4834 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6K11_RS28040 (TUM12137_52310) | 5253..5519 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6K11_RS27090 | 5451..6136 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6K11_RS27095 (TUM12137_52330) | 6809..8317 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6K11_RS27100 | 8398..8577 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6K11_RS27105 (TUM12137_52340) | 8859..9935 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6K11_RS27110 | 9952..10228 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6K11_RS27115 | 10343..10519 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6K11_RS27120 (TUM12137_52350) | 10534..11370 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6K11_RS27125 (TUM12137_52360) | 11435..11833 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6K11_RS27130 (TUM12137_52370) | 11877..12986 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6K11_RS27135 (TUM12137_52380) | 13021..13296 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6K11_RS27145 (TUM12137_52410) | 14718..15287 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6K11_RS27150 (TUM12137_52420) | 15527..16741 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6K11_RS27155 (TUM12137_52430) | 16775..18208 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6K11_RS27160 (TUM12137_52440) | 18307..18579 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6K11_RS27165 (TUM12137_52450) | 18590..18796 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6K11_RS27170 (TUM12137_52460) | 18801..19442 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6K11_RS27175 (TUM12137_52470) | 19498..19809 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6K11_RS27180 (TUM12137_52480) | 19845..20159 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6K11_RS27185 (TUM12137_52490) | 20156..20500 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6K11_RS27190 (TUM12137_52500) | 20516..20821 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6K11_RS27195 (TUM12137_52510) | 20930..21667 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6K11_RS27200 (TUM12137_52520) | 21676..21957 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6K11_RS27205 (TUM12137_52530) | 21967..22260 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6K11_RS27210 (TUM12137_52540) | 22310..22627 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6K11_RS27215 (TUM12137_52550) | 22627..25227 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6K11_RS27220 (TUM12137_52560) | 25245..25958 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6K11_RS27225 (TUM12137_52570) | 25966..26193 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6K11_RS27230 (TUM12137_52580) | 26209..27249 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6K11_RS27235 (TUM12137_52590) | 27468..28166 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6K11_RS27240 (TUM12137_52600) | 28177..29061 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6K11_RS27245 (TUM12137_52610) | 29061..30221 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6K11_RS27250 (TUM12137_52620) | 30263..31258 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6K11_RS27255 (TUM12137_52630) | 31258..31524 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6K11_RS27260 (TUM12137_52640) | 31730..31861 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6K11_RS27265 (TUM12137_52650) | 31918..32910 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6K11_RS27270 | 32959..33114 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6K11_RS27275 (TUM12137_52660) | 33409..35124 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6K11_RS27280 (TUM12137_52670) | 35234..38263 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6K11_RS27285 (TUM12137_52680) | 38370..39395 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6K11_RS27290 (TUM12137_52690) | 39392..40171 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6K11_RS27295 (TUM12137_52700) | 40459..41340 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6K11_RS27300 (TUM12137_52710) | 41590..42909 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6K11_RS27305 (TUM12137_52720) | 43186..44370 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6K11_RS27310 (TUM12137_52730) | 44472..44702 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6K11_RS27315 (TUM12137_52740) | 44874..45233 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6K11_RS27320 | 45890..46300 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6K11_RS27325 (TUM12137_52750) | 46399..47019 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6K11_RS27330 (TUM12137_52760) | 47108..50005 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6K11_RS27335 (TUM12137_52770) | 50078..50782 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6K11_RS27340 | 50832..50942 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6K11_RS27345 | 51002..51826 | + | 825 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6K11_RS27350 (TUM12137_52800) | 52026..52343 | + | 318 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6K11_RS27355 (TUM12137_52810) | 52526..53386 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6K11_RS27360 (TUM12137_52820) | 53536..53907 | - | 372 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6K11_RS27365 (TUM12137_52830) | 53972..55222 | - | 1251 | Protein_59 | transposase | - |
| K6K11_RS27370 (TUM12137_52840) | 55297..55965 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6K11_RS27375 (TUM12137_52850) | 56001..56237 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6K11_RS27380 (TUM12137_52860) | 56234..56596 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6K11_RS27385 (TUM12137_52870) | 56614..58308 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6K11_RS27390 (TUM12137_52880) | 58360..58782 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6K11_RS27395 | 58818..58928 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6K11_RS27405 (TUM12137_52910) | 59696..60385 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6K11_RS27410 (TUM12137_52920) | 60459..60875 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6K11_RS27415 (TUM12137_52930) | 60872..61102 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6K11_RS27420 | 61059..61520 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6K11_RS27425 (TUM12137_52940) | 62078..63397 | + | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6K11_RS27430 (TUM12137_52950) | 63647..64528 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6K11_RS27435 (TUM12137_52960) | 64816..65595 | - | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6K11_RS27440 (TUM12137_52970) | 65592..66617 | - | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6K11_RS27445 (TUM12137_52980) | 66724..69753 | - | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6K11_RS27450 (TUM12137_52990) | 69863..71578 | + | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6K11_RS27455 (TUM12137_53000) | 71630..73315 | - | 1686 | Protein_77 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6K11_RS27460 (TUM12137_53020) | 73477..74034 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6K11_RS27465 (TUM12137_53030) | 74268..74822 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6K11_RS27470 (TUM12137_53040) | 74892..75107 | + | 216 | Protein_80 | IS6 family transposase IS15 | Transposase |
| K6K11_RS27475 (TUM12137_53050) | 75173..75877 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6K11_RS27480 (TUM12137_53060) | 75932..76102 | + | 171 | Protein_82 | serine hydrolase | - |
| K6K11_RS28045 (TUM12137_53070) | 76233..76331 | - | 99 | Protein_83 | hypothetical protein | - |
| K6K11_RS27485 | 76460..76564 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6K11_RS27490 (TUM12137_53080) | 77094..77960 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6K11_RS27495 (TUM12137_53090) | 78137..78406 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6K11_RS27500 (TUM12137_53100) | 78821..80026 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6K11_RS27505 (TUM12137_53110) | 80026..81000 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6K11_RS27510 (TUM12137_53120) | 81082..82353 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6K11_RS27515 (TUM12137_53130) | 82353..82784 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6K11_RS27520 (TUM12137_53140) | 83190..84677 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6K11_RS27525 | 84829..85526 | + | 698 | WP_223229472.1 | IS1 family transposase IS1X3 | Transposase |
| K6K11_RS27530 | 85536..85844 | + | 309 | Protein_93 | replication initiation protein | - |
| K6K11_RS27535 (TUM12137_53170) | 87247..88215 | + | 969 | WP_077259757.1 | IS5 family transposase IS903B | Transposase |
| K6K11_RS27540 (TUM12137_53180) | 88355..88741 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| K6K11_RS27545 (TUM12137_53190) | 89323..89556 | + | 234 | Protein_96 | IS5 family transposase ISPan1 | Transposase |
| K6K11_RS27550 (TUM12137_53200) | 89589..92555 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6K11_RS27555 (TUM12137_53210) | 92559..93119 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6K11_RS27560 (TUM12137_53220) | 93295..93645 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6K11_RS27565 (TUM12137_53230) | 93848..94861 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6K11_RS27570 (TUM12137_53240) | 95028..95870 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6K11_RS27575 (TUM12137_53250) | 95966..96574 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6K11_RS27580 (TUM12137_53260) | 96632..97470 | + | 839 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6K11_RS27585 | 97685..98944 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6K11_RS27590 (TUM12137_53280) | 99037..99875 | + | 839 | Protein_105 | Streptomycin 3''-adenylyltransferase | ARG |
| K6K11_RS27595 (TUM12137_53290) | 99998..100330 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6K11_RS27600 (TUM12137_53300) | 100577..101209 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6K11_RS27605 (TUM12137_53310) | 101524..102504 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6K11_RS27610 (TUM12137_53320) | 102610..103314 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6K11_RS27615 (TUM12137_53330) | 103428..104204 | + | 777 | WP_001199192.1 | hypothetical protein | ARG |
| K6K11_RS27620 (TUM12137_53350) | 104433..105458 | + | 1026 | WP_000742814.1 | hypothetical protein | ARG |
| K6K11_RS27625 | 105533..105820 | + | 288 | Protein_112 | AAC(3) family N-acetyltransferase | - |
| K6K11_RS27630 (TUM12137_53360) | 105880..106632 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6K11_RS27635 (TUM12137_53370) | 106694..107575 | + | 882 | Protein_114 | Tn3 family transposase | - |
| K6K11_RS27640 | 107738..107821 | - | 84 | Protein_115 | SOS response-associated peptidase | - |
| K6K11_RS27645 (TUM12137_53380) | 108688..108963 | + | 276 | Protein_116 | Phospholipase D | VF |
| K6K11_RS27650 (TUM12137_53390) | 109136..109450 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6K11_RS27655 (TUM12137_53400) | 109705..110061 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6K11_RS27660 (TUM12137_53410) | 110051..110452 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6K11_RS27665 (TUM12137_53420) | 110449..110739 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6K11_RS27670 (TUM12137_53430) | 110803..111201 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6K11_RS27675 (TUM12137_53440) | 111201..114437 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6K11_RS27680 (TUM12137_53450) | 114437..115966 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6K11_RS27685 (TUM12137_53460) | 115968..116384 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6K11_RS27690 (TUM12137_53470) | 116941..117327 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6K11_RS27695 (TUM12137_53480) | 117336..118052 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6K11_RS27700 (TUM12137_53490) | 118054..118422 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6K11_RS27705 (TUM12137_53500) | 118623..118967 | + | 345 | WP_012561137.1 | hypothetical protein | - |
| K6K11_RS27710 (TUM12137_53510) | 119429..119608 | - | 180 | WP_012561134.1 | protein CcgAI | - |
| K6K11_RS27715 (TUM12137_53520) | 120959..121291 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6K11_RS27720 (TUM12137_53530) | 121500..121784 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6K11_RS28050 | 121853..122053 | - | 201 | WP_020319888.1 | hypothetical protein | - |
| K6K11_RS27730 (TUM12137_53550) | 122209..122505 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6K11_RS27735 (TUM12137_53560) | 123389..123628 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6K11_RS27740 (TUM12137_53570) | 123638..124042 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6K11_RS27745 (TUM12137_53580) | 124100..124525 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6K11_RS27750 (TUM12137_53590) | 124941..125381 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6K11_RS27755 (TUM12137_53600) | 125369..126634 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6K11_RS27760 (TUM12137_53610) | 126785..127576 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6K11_RS27765 (TUM12137_53620) | 127591..127932 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|