MGE detailed information
MGE type: Conjugative plasmid MGE length: 123760 bp
Accession: NZ_AP024773 Location: 1..123760 Organism: Klebsiella pneumoniae strain TUM12133 Replicon: plasmid IncN-R
Accession: NZ_AP024773 Location: 1..123760 Organism: Klebsiella pneumoniae strain TUM12133 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J98_RS25985 (TUM12133_50040) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6J98_RS25990 (TUM12133_50050) | 2221..2520 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6J98_RS25995 (TUM12133_50060) | 2592..5243 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J98_RS26925 (TUM12133_50080) | 5662..5928 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J98_RS26000 | 5860..6545 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6J98_RS26005 (TUM12133_50100) | 7218..8726 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J98_RS26010 | 8807..8986 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6J98_RS26015 (TUM12133_50110) | 9268..10344 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J98_RS26020 | 10361..10637 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6J98_RS26025 | 10752..10928 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J98_RS26030 (TUM12133_50120) | 10943..11779 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J98_RS26035 (TUM12133_50130) | 11844..12242 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J98_RS26040 (TUM12133_50140) | 12286..13395 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J98_RS26045 (TUM12133_50150) | 13430..13705 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J98_RS26055 (TUM12133_50180) | 15127..15696 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J98_RS26060 (TUM12133_50190) | 15936..17150 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J98_RS26065 (TUM12133_50200) | 17184..18617 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J98_RS26070 (TUM12133_50210) | 18716..18988 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6J98_RS26075 (TUM12133_50220) | 18999..19205 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J98_RS26080 (TUM12133_50230) | 19210..19851 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J98_RS26085 (TUM12133_50240) | 19907..20218 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J98_RS26090 (TUM12133_50250) | 20254..20568 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J98_RS26095 (TUM12133_50260) | 20565..20909 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J98_RS26100 (TUM12133_50270) | 20925..21230 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J98_RS26105 (TUM12133_50280) | 21339..22076 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J98_RS26110 (TUM12133_50290) | 22085..22366 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J98_RS26115 (TUM12133_50300) | 22376..22669 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J98_RS26120 (TUM12133_50310) | 22719..23036 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J98_RS26125 (TUM12133_50320) | 23036..25636 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J98_RS26130 (TUM12133_50330) | 25654..26367 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J98_RS26135 (TUM12133_50340) | 26375..26602 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J98_RS26140 (TUM12133_50350) | 26618..27658 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J98_RS26145 (TUM12133_50360) | 27877..28575 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J98_RS26150 (TUM12133_50370) | 28586..29470 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J98_RS26155 (TUM12133_50380) | 29470..30630 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J98_RS26160 (TUM12133_50390) | 30672..31667 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J98_RS26165 (TUM12133_50400) | 31667..31933 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6J98_RS26170 (TUM12133_50410) | 32139..32270 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6J98_RS26175 (TUM12133_50420) | 32327..33319 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J98_RS26180 | 33368..33523 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J98_RS26185 (TUM12133_50430) | 33818..35533 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J98_RS26190 (TUM12133_50440) | 35643..38672 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J98_RS26195 (TUM12133_50450) | 38779..39804 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J98_RS26200 (TUM12133_50460) | 39801..40580 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J98_RS26205 (TUM12133_50470) | 40868..41749 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J98_RS26210 (TUM12133_50480) | 41999..43318 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J98_RS26215 (TUM12133_50490) | 43595..44779 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J98_RS26220 (TUM12133_50500) | 44881..45111 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6J98_RS26225 (TUM12133_50510) | 45283..45642 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J98_RS26230 | 46299..46709 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J98_RS26235 (TUM12133_50520) | 46808..47428 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J98_RS26240 (TUM12133_50530) | 47517..50414 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J98_RS26245 (TUM12133_50540) | 50487..51191 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J98_RS26250 | 51241..51351 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J98_RS26255 | 51368..52233 | + | 866 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J98_RS26260 (TUM12133_50570) | 52433..52750 | + | 318 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J98_RS26265 (TUM12133_50580) | 52933..53793 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6J98_RS26270 (TUM12133_50590) | 53943..54314 | - | 372 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6J98_RS26275 (TUM12133_50600) | 54379..55629 | - | 1251 | Protein_59 | transposase | - |
| K6J98_RS26280 (TUM12133_50610) | 55704..56372 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J98_RS26285 (TUM12133_50620) | 56408..56644 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J98_RS26290 (TUM12133_50630) | 56641..57003 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J98_RS26295 (TUM12133_50640) | 57021..58715 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J98_RS26300 (TUM12133_50650) | 58767..59189 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J98_RS26305 | 59225..59335 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6J98_RS26315 (TUM12133_50680) | 60103..60792 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6J98_RS26320 (TUM12133_50690) | 60866..61282 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J98_RS26325 (TUM12133_50700) | 61279..61509 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J98_RS26330 | 61466..61927 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J98_RS26335 (TUM12133_50710) | 62071..62421 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J98_RS26340 (TUM12133_50720) | 62472..63215 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J98_RS26345 (TUM12133_50730) | 63212..63988 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J98_RS26930 (TUM12133_50740) | 64046..64225 | - | 180 | Protein_74 | hypothetical protein | - |
| K6J98_RS26350 (TUM12133_50750) | 64260..67265 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J98_RS26355 (TUM12133_50770) | 67427..67984 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J98_RS26360 (TUM12133_50780) | 68218..68772 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J98_RS26365 (TUM12133_50790) | 68842..69057 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6J98_RS26370 (TUM12133_50800) | 69123..69827 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J98_RS26375 (TUM12133_50810) | 69882..70052 | + | 171 | Protein_80 | serine hydrolase | - |
| K6J98_RS26935 (TUM12133_50820) | 70183..70281 | - | 99 | Protein_81 | hypothetical protein | - |
| K6J98_RS26380 | 70410..70514 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J98_RS26385 (TUM12133_50830) | 71044..71910 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J98_RS26390 (TUM12133_50840) | 72087..72356 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J98_RS26395 (TUM12133_50850) | 72771..73976 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J98_RS26400 (TUM12133_50860) | 73976..74950 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J98_RS26405 (TUM12133_50870) | 75032..76303 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J98_RS26410 (TUM12133_50880) | 76303..76734 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J98_RS26415 (TUM12133_50890) | 77140..78627 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6J98_RS26420 | 78778..79474 | + | 697 | WP_020277971.1 | IS1 family transposase IS1X3 | Transposase |
| K6J98_RS26425 | 79484..79792 | + | 309 | Protein_91 | replication initiation protein | - |
| K6J98_RS26430 (TUM12133_50920) | 81193..82161 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
| K6J98_RS26435 (TUM12133_50930) | 82300..82686 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| K6J98_RS26440 (TUM12133_50940) | 83268..83501 | + | 234 | Protein_94 | IS5 family transposase ISPan1 | Transposase |
| K6J98_RS26445 (TUM12133_50950) | 83534..86500 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J98_RS26450 (TUM12133_50960) | 86504..87064 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J98_RS26455 (TUM12133_50970) | 87240..87590 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J98_RS26460 (TUM12133_50990) | 87793..88806 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J98_RS26465 (TUM12133_51000) | 88973..89815 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J98_RS26470 (TUM12133_51010) | 89911..90519 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J98_RS26475 (TUM12133_51020) | 90577..91415 | + | 839 | Protein_101 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J98_RS26480 | 91630..92889 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J98_RS26485 (TUM12133_51040) | 92982..93820 | + | 839 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J98_RS26490 (TUM12133_51050) | 93943..94275 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J98_RS26495 (TUM12133_51060) | 94522..95154 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J98_RS26500 (TUM12133_51070) | 95469..96449 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J98_RS26505 (TUM12133_51080) | 96555..97259 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J98_RS26510 (TUM12133_51090) | 97373..98149 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6J98_RS26515 (TUM12133_51110) | 98378..99403 | + | 1026 | WP_000742814.1 | hypothetical protein | ARG |
| K6J98_RS26520 | 99478..99765 | + | 288 | Protein_110 | AAC(3) family N-acetyltransferase | - |
| K6J98_RS26525 (TUM12133_51120) | 99825..100577 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J98_RS26530 (TUM12133_51130) | 100639..101520 | + | 882 | Protein_112 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| K6J98_RS26535 | 101683..101766 | - | 84 | Protein_113 | SOS response-associated peptidase | - |
| K6J98_RS26540 (TUM12133_51140) | 102632..102907 | + | 276 | Protein_114 | Phospholipase D | VF |
| K6J98_RS26545 (TUM12133_51150) | 103080..103394 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J98_RS26550 (TUM12133_51160) | 103649..104005 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J98_RS26555 (TUM12133_51170) | 103995..104396 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J98_RS26560 (TUM12133_51180) | 104393..104683 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J98_RS26565 (TUM12133_51190) | 104747..105145 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J98_RS26570 (TUM12133_51200) | 105145..108381 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J98_RS26575 (TUM12133_51210) | 108381..109910 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J98_RS26580 (TUM12133_51220) | 109912..110328 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J98_RS26585 (TUM12133_51230) | 110885..111271 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6J98_RS26590 (TUM12133_51240) | 111280..111996 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J98_RS26595 (TUM12133_51250) | 111999..112367 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6J98_RS26940 | 112568..112849 | + | 282 | WP_228740250.1 | hypothetical protein | - |
| K6J98_RS27035 | 113372..113550 | - | 179 | Protein_127 | protein CcgAI | - |
| K6J98_RS26605 (TUM12133_51270) | 114380..114889 | - | 510 | WP_012561131.1 | antirestriction protein ArdA | - |
| K6J98_RS26610 (TUM12133_51280) | 116241..116573 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6J98_RS26615 (TUM12133_51290) | 116780..117064 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6J98_RS26945 (TUM12133_51300) | 117133..117333 | - | 201 | WP_020319888.1 | hypothetical protein | - |
| K6J98_RS26625 (TUM12133_51310) | 117488..117784 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J98_RS26630 (TUM12133_51320) | 118667..118906 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J98_RS27040 | 118916..119319 | - | 404 | Protein_134 | antirestriction protein ArdAB regulator ArdR | - |
| K6J98_RS26640 (TUM12133_51350) | 119377..119802 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J98_RS26645 (TUM12133_51360) | 120216..120656 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J98_RS26650 | 120644..121907 | + | 1264 | Protein_137 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J98_RS26655 (TUM12133_51390) | 122055..122846 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J98_RS26660 (TUM12133_51400) | 122866..123201 | - | 336 | Protein_139 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|