MGE detailed information
MGE type: Conjugative plasmid MGE length: 123805 bp
Accession: NZ_AP024770 Location: 1..123805 Organism: Klebsiella pneumoniae strain TUM12132 Replicon: plasmid IncN-R
Accession: NZ_AP024770 Location: 1..123805 Organism: Klebsiella pneumoniae strain TUM12132 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J84_RS25970 (TUM12132_49850) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6J84_RS25975 | 1150..1392 | + | 243 | WP_228740252.1 | RepB family plasmid replication initiator protein | - |
| K6J84_RS25980 (TUM12132_49860) | 2262..2561 | + | 300 | Protein_2 | IS66 family transposase ISEc22 | Transposase |
| K6J84_RS25985 (TUM12132_49870) | 2633..5284 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J84_RS26915 (TUM12132_49890) | 5703..5969 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J84_RS25990 | 5901..6586 | + | 686 | Protein_5 | IS3 family transposase ISEc14 | Transposase |
| K6J84_RS25995 (TUM12132_49910) | 7259..8767 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J84_RS26000 | 8848..9027 | + | 180 | Protein_7 | DDE-type integrase/transposase/recombinase | - |
| K6J84_RS26005 (TUM12132_49920) | 9309..10385 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J84_RS26010 | 10402..10678 | + | 277 | Protein_9 | IS3 family transposase | - |
| K6J84_RS26015 | 10793..10969 | + | 177 | Protein_10 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J84_RS26020 (TUM12132_49930) | 10984..11820 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J84_RS26025 (TUM12132_49940) | 11885..12283 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J84_RS26030 (TUM12132_49950) | 12327..13436 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J84_RS26035 (TUM12132_49960) | 13471..13746 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J84_RS26045 (TUM12132_49990) | 15168..15737 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J84_RS26050 (TUM12132_50000) | 15977..17191 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J84_RS26055 (TUM12132_50010) | 17225..18658 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J84_RS26060 (TUM12132_50020) | 18757..19029 | + | 273 | Protein_19 | IS1 family transposase IS1X2 | Transposase |
| K6J84_RS26065 (TUM12132_50030) | 19040..19246 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J84_RS26070 (TUM12132_50040) | 19288..19890 | - | 603 | WP_228740251.1 | restriction endonuclease | - |
| K6J84_RS26075 (TUM12132_50050) | 19946..20257 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J84_RS26080 (TUM12132_50060) | 20293..20607 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J84_RS26085 (TUM12132_50070) | 20604..20948 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J84_RS26090 (TUM12132_50080) | 20964..21269 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J84_RS26095 (TUM12132_50090) | 21378..22115 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J84_RS26100 (TUM12132_50100) | 22124..22405 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J84_RS26105 (TUM12132_50110) | 22415..22708 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J84_RS26110 (TUM12132_50120) | 22758..23075 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J84_RS26115 (TUM12132_50130) | 23075..25675 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J84_RS26120 (TUM12132_50140) | 25693..26406 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J84_RS26125 (TUM12132_50150) | 26414..26641 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J84_RS26130 (TUM12132_50160) | 26657..27697 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J84_RS26135 (TUM12132_50170) | 27916..28614 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J84_RS26140 (TUM12132_50180) | 28625..29509 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J84_RS26145 (TUM12132_50190) | 29509..30669 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J84_RS26150 (TUM12132_50200) | 30711..31706 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J84_RS26155 (TUM12132_50210) | 31706..31972 | + | 267 | Protein_38 | hypothetical protein | VF |
| K6J84_RS26160 (TUM12132_50220) | 32178..32309 | - | 132 | Protein_39 | hypothetical protein | VF |
| K6J84_RS26165 (TUM12132_50230) | 32366..33358 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J84_RS26170 | 33407..33562 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J84_RS26175 (TUM12132_50240) | 33857..35572 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J84_RS26180 (TUM12132_50250) | 35682..38711 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J84_RS26185 (TUM12132_50260) | 38818..39843 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J84_RS26190 (TUM12132_50270) | 39840..40619 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J84_RS26195 (TUM12132_50280) | 40907..41788 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J84_RS26200 (TUM12132_50290) | 42038..43357 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J84_RS26205 (TUM12132_50300) | 43634..44818 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J84_RS26210 (TUM12132_50310) | 44920..45150 | + | 231 | Protein_49 | IS5 family transposase ISAeme7 | Transposase |
| K6J84_RS26215 (TUM12132_50320) | 45322..45681 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J84_RS26220 | 46338..46748 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J84_RS26225 (TUM12132_50330) | 46847..47467 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J84_RS26230 (TUM12132_50340) | 47556..50453 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J84_RS26235 (TUM12132_50350) | 50526..51230 | + | 705 | Protein_54 | IS6 family transposase IS15DII | Transposase |
| K6J84_RS26240 | 51280..51390 | + | 111 | Protein_55 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J84_RS26245 | 51450..52273 | + | 824 | Protein_56 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J84_RS26250 (TUM12132_50380) | 52473..52790 | + | 318 | Protein_57 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J84_RS26255 (TUM12132_50390) | 52973..53833 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6J84_RS26260 (TUM12132_50400) | 53983..54354 | - | 372 | Protein_59 | IS6 family transposase IS15DII | Transposase |
| K6J84_RS26265 (TUM12132_50410) | 54419..55669 | - | 1251 | Protein_60 | transposase | - |
| K6J84_RS26270 (TUM12132_50420) | 55744..56412 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J84_RS26275 (TUM12132_50430) | 56448..56684 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J84_RS26280 (TUM12132_50440) | 56681..57043 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J84_RS26285 (TUM12132_50450) | 57061..58755 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J84_RS26290 (TUM12132_50460) | 58807..59229 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J84_RS26295 | 59265..59375 | - | 111 | Protein_66 | mercuric transport protein periplasmic component | - |
| K6J84_RS26305 (TUM12132_50490) | 60143..60832 | - | 690 | Protein_68 | AAA family ATPase | - |
| K6J84_RS26310 (TUM12132_50500) | 60906..61322 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J84_RS26315 (TUM12132_50510) | 61319..61549 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J84_RS26320 | 61506..61967 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J84_RS26325 (TUM12132_50520) | 62111..62461 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J84_RS26330 (TUM12132_50530) | 62512..63255 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J84_RS26335 (TUM12132_50540) | 63252..64028 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J84_RS26920 (TUM12132_50550) | 64086..64265 | - | 180 | Protein_75 | hypothetical protein | - |
| K6J84_RS26340 (TUM12132_50560) | 64300..67305 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J84_RS26345 (TUM12132_50580) | 67467..68024 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J84_RS26350 (TUM12132_50590) | 68258..68812 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J84_RS26355 (TUM12132_50600) | 68882..69097 | + | 216 | Protein_79 | IS6 family transposase IS15 | Transposase |
| K6J84_RS26360 (TUM12132_50610) | 69163..69867 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J84_RS26365 (TUM12132_50620) | 69922..70092 | + | 171 | Protein_81 | serine hydrolase | - |
| K6J84_RS26925 (TUM12132_50630) | 70223..70321 | - | 99 | Protein_82 | hypothetical protein | - |
| K6J84_RS26370 | 70450..70554 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J84_RS26375 (TUM12132_50640) | 71084..71950 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J84_RS26380 (TUM12132_50650) | 72127..72396 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J84_RS26385 (TUM12132_50660) | 72811..74016 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J84_RS26390 (TUM12132_50670) | 74016..74990 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J84_RS26395 (TUM12132_50680) | 75072..76343 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J84_RS26400 (TUM12132_50690) | 76343..76774 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J84_RS26405 (TUM12132_50700) | 77180..78667 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6J84_RS26410 | 78818..79514 | + | 697 | WP_020277971.1 | IS1 family transposase IS1X3 | Transposase |
| K6J84_RS26415 | 79524..79832 | + | 309 | Protein_92 | replication initiation protein | - |
| K6J84_RS26420 (TUM12132_50730) | 81234..82202 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
| K6J84_RS27020 (TUM12132_50740) | 82341..82526 | - | 186 | WP_232585769.1 | StbA | - |
| K6J84_RS26430 (TUM12132_50750) | 83308..83541 | + | 234 | Protein_95 | IS5 family transposase ISPan1 | Transposase |
| K6J84_RS26435 (TUM12132_50760) | 83574..86540 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J84_RS26440 (TUM12132_50770) | 86544..87104 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J84_RS26445 (TUM12132_50780) | 87280..87630 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J84_RS26450 (TUM12132_50790) | 87833..88846 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J84_RS26455 (TUM12132_50800) | 89013..89855 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J84_RS26460 (TUM12132_50810) | 89951..90559 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J84_RS26465 (TUM12132_50820) | 90617..91455 | + | 839 | Protein_102 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J84_RS26470 | 91670..92929 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J84_RS26475 (TUM12132_50840) | 93022..93860 | + | 839 | Protein_104 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J84_RS26480 (TUM12132_50850) | 93983..94315 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J84_RS26485 (TUM12132_50860) | 94562..95194 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J84_RS26490 (TUM12132_50870) | 95509..96489 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J84_RS26495 (TUM12132_50880) | 96595..97299 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J84_RS26500 (TUM12132_50890) | 97413..98189 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6J84_RS26505 (TUM12132_50910) | 98418..99443 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J84_RS26510 | 99518..99805 | + | 288 | Protein_111 | AAC(3) family N-acetyltransferase | - |
| K6J84_RS26515 (TUM12132_50920) | 99865..100617 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J84_RS26520 (TUM12132_50930) | 100679..101560 | + | 882 | Protein_113 | Tn3 family transposase | - |
| K6J84_RS26525 | 101722..101805 | - | 84 | Protein_114 | SOS response-associated peptidase | - |
| K6J84_RS26530 (TUM12132_50940) | 102671..102946 | + | 276 | Protein_115 | Phospholipase D | VF |
| K6J84_RS26535 (TUM12132_50950) | 103119..103433 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J84_RS26540 (TUM12132_50960) | 103688..104044 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J84_RS26545 (TUM12132_50970) | 104034..104435 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J84_RS26550 (TUM12132_50980) | 104432..104722 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J84_RS26555 (TUM12132_50990) | 104786..105184 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J84_RS26560 (TUM12132_51000) | 105184..108420 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J84_RS26565 (TUM12132_51010) | 108420..109949 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J84_RS26570 (TUM12132_51020) | 109951..110367 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J84_RS26575 (TUM12132_51030) | 110924..111310 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6J84_RS26580 (TUM12132_51040) | 111319..112035 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J84_RS26585 (TUM12132_51050) | 112037..112405 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6J84_RS26935 | 112606..112887 | + | 282 | WP_228740250.1 | hypothetical protein | - |
| K6J84_RS27025 | 113410..113588 | - | 179 | Protein_128 | protein CcgAI | - |
| K6J84_RS26595 (TUM12132_51070) | 114418..114927 | - | 510 | WP_012561131.1 | antirestriction protein ArdA | - |
| K6J84_RS26600 (TUM12132_51080) | 116274..116606 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6J84_RS26605 (TUM12132_51090) | 116816..117100 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6J84_RS26940 | 117169..117369 | - | 201 | WP_020319888.1 | hypothetical protein | - |
| K6J84_RS26615 (TUM12132_51110) | 117525..117821 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J84_RS26620 (TUM12132_51130) | 118703..118942 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J84_RS26625 (TUM12132_51140) | 118952..119356 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J84_RS26630 (TUM12132_51150) | 119414..119839 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J84_RS26635 (TUM12132_51160) | 120255..120695 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J84_RS26640 (TUM12132_51170) | 120683..121948 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J84_RS26645 (TUM12132_51180) | 122099..122890 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J84_RS26650 (TUM12132_51190) | 122905..123246 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|