MGE detailed information
MGE type: Conjugative plasmid MGE length: 123514 bp
Accession: NZ_AP024754 Location: 1..123514 Organism: Klebsiella pneumoniae strain TUM12127 Replicon: plasmid IncN-R
Accession: NZ_AP024754 Location: 1..123514 Organism: Klebsiella pneumoniae strain TUM12127 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J87_RS26395 (TUM12127_50790) | 1..720 | + | 720 | WP_221281832.1 | replication initiation protein | - |
| K6J87_RS26400 (TUM12127_50800) | 2221..2520 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6J87_RS26405 (TUM12127_50810) | 2592..5243 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J87_RS27365 (TUM12127_50830) | 5662..5928 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J87_RS26410 | 5860..6545 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6J87_RS26415 (TUM12127_50850) | 7218..8726 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J87_RS26420 | 8807..8986 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6J87_RS26425 (TUM12127_50860) | 9268..10344 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J87_RS26430 | 10361..10637 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6J87_RS26435 | 10752..10928 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J87_RS26440 (TUM12127_50870) | 10943..11779 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J87_RS26445 (TUM12127_50880) | 11844..12242 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J87_RS26450 (TUM12127_50890) | 12286..13395 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J87_RS26455 (TUM12127_50900) | 13430..13705 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J87_RS26465 (TUM12127_50930) | 15127..15696 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J87_RS26470 (TUM12127_50940) | 15936..17150 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J87_RS26475 (TUM12127_50950) | 17184..18617 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J87_RS26480 (TUM12127_50960) | 18716..18988 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6J87_RS26485 (TUM12127_50970) | 18999..19205 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J87_RS26490 (TUM12127_50980) | 19210..19851 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J87_RS26495 (TUM12127_50990) | 19907..20218 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J87_RS26500 (TUM12127_51000) | 20254..20568 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J87_RS26505 (TUM12127_51010) | 20565..20909 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J87_RS26510 (TUM12127_51020) | 20925..21230 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J87_RS26515 (TUM12127_51030) | 21339..22076 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J87_RS26520 (TUM12127_51040) | 22085..22366 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J87_RS26525 (TUM12127_51050) | 22376..22669 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J87_RS26530 (TUM12127_51060) | 22719..23036 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J87_RS26535 (TUM12127_51070) | 23036..25636 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J87_RS26540 (TUM12127_51080) | 25654..26367 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J87_RS26545 (TUM12127_51090) | 26375..26602 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J87_RS26550 (TUM12127_51100) | 26618..27658 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J87_RS26555 (TUM12127_51110) | 27877..28575 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J87_RS26560 (TUM12127_51120) | 28586..29470 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J87_RS26565 (TUM12127_51130) | 29470..30630 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J87_RS26570 (TUM12127_51140) | 30672..31667 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J87_RS26575 (TUM12127_51150) | 31667..31933 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6J87_RS26580 (TUM12127_51160) | 32139..32270 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6J87_RS26585 (TUM12127_51170) | 32327..33319 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J87_RS26590 | 33368..33523 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J87_RS26595 (TUM12127_51180) | 33818..35533 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J87_RS26600 (TUM12127_51190) | 35643..38672 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J87_RS26605 (TUM12127_51200) | 38779..39804 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J87_RS26610 (TUM12127_51210) | 39801..40580 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J87_RS26615 (TUM12127_51220) | 40868..41749 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J87_RS26620 (TUM12127_51230) | 41999..43318 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J87_RS26625 (TUM12127_51240) | 43595..44779 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J87_RS26630 (TUM12127_51250) | 44881..45111 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6J87_RS26635 (TUM12127_51260) | 45283..45642 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J87_RS26640 | 46299..46709 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J87_RS26645 (TUM12127_51270) | 46808..47428 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J87_RS26650 (TUM12127_51280) | 47517..50414 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J87_RS26655 (TUM12127_51290) | 50487..51192 | + | 706 | Protein_53 | IS6 family transposase IS15DII | Transposase |
| K6J87_RS26660 | 51247..51354 | + | 108 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J87_RS26665 | 51439..52240 | + | 802 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J87_RS26670 (TUM12127_51320) | 52440..52757 | + | 318 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J87_RS26675 (TUM12127_51330) | 52940..53800 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6J87_RS26680 (TUM12127_51340) | 53990..54322 | - | 333 | Protein_58 | IS6 family transposase IS15DI | Transposase |
| K6J87_RS26685 (TUM12127_51350) | 54387..55637 | - | 1251 | Protein_59 | transposase | - |
| K6J87_RS26690 (TUM12127_51360) | 55712..56380 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J87_RS26695 (TUM12127_51370) | 56416..56652 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J87_RS26700 (TUM12127_51380) | 56649..57011 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J87_RS26705 (TUM12127_51390) | 57029..58723 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J87_RS26710 (TUM12127_51400) | 58775..59197 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J87_RS26715 | 59233..59343 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6J87_RS26725 (TUM12127_51430) | 60111..60800 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6J87_RS26730 (TUM12127_51440) | 60874..61290 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J87_RS26735 (TUM12127_51450) | 61287..61517 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J87_RS26740 | 61474..61935 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J87_RS26745 (TUM12127_51460) | 62079..62429 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J87_RS26750 (TUM12127_51470) | 62480..63223 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J87_RS26755 (TUM12127_51480) | 63220..63996 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J87_RS27370 (TUM12127_51490) | 64054..64233 | - | 180 | Protein_74 | hypothetical protein | - |
| K6J87_RS26760 (TUM12127_51500) | 64268..67273 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J87_RS26765 (TUM12127_51520) | 67435..67992 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J87_RS26770 (TUM12127_51530) | 68226..68780 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J87_RS26775 (TUM12127_51540) | 68850..69065 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6J87_RS26780 (TUM12127_51550) | 69131..69835 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J87_RS26785 (TUM12127_51560) | 69890..70060 | + | 171 | Protein_80 | serine hydrolase | - |
| K6J87_RS27375 (TUM12127_51570) | 70191..70289 | - | 99 | Protein_81 | hypothetical protein | - |
| K6J87_RS26790 | 70418..70522 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J87_RS26795 (TUM12127_51580) | 71052..71918 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J87_RS26800 (TUM12127_51590) | 72491..73696 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J87_RS26805 (TUM12127_51600) | 73696..74670 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J87_RS26810 (TUM12127_51610) | 74752..76023 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J87_RS26815 (TUM12127_51620) | 76023..76454 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J87_RS26820 | 76859..78346 | + | 1488 | Protein_88 | Group II intron-encoded protein LtrA | VF |
| K6J87_RS26825 | 78497..79193 | + | 697 | WP_020277971.1 | IS1 family transposase IS1X3 | Transposase |
| K6J87_RS26830 | 79203..79511 | + | 309 | Protein_90 | replication initiation protein | - |
| K6J87_RS26835 | 80928..81896 | + | 969 | Protein_91 | IS5 family transposase ISPan1 | Transposase |
| K6J87_RS26840 (TUM12127_51710) | 82035..82420 | - | 386 | Protein_92 | plasmid stabilization protein StbA | - |
| K6J87_RS26845 (TUM12127_51720) | 83002..83235 | + | 234 | Protein_93 | transposase | - |
| K6J87_RS26850 (TUM12127_51730) | 83268..86234 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J87_RS26855 (TUM12127_51740) | 86238..86798 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J87_RS26860 (TUM12127_51750) | 86974..87324 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J87_RS26865 | 87527..88537 | - | 1011 | Protein_97 | IS91 family transposase ISAzo26 | Transposase |
| K6J87_RS27380 (TUM12127_51780) | 88705..88944 | + | 240 | WP_228740592.1 | hypothetical protein | - |
| K6J87_RS27385 (TUM12127_51790) | 89066..89545 | + | 480 | WP_267461051.1 | alpha/beta fold hydrolase | - |
| K6J87_RS26875 (TUM12127_51800) | 89641..90246 | + | 606 | WP_228740593.1 | HAD family hydrolase | - |
| K6J87_RS26880 (TUM12127_51820) | 90304..91147 | + | 844 | Protein_101 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J87_RS26885 | 91362..92620 | + | 1259 | Protein_102 | Bicyclomycin resistance protein | ARG |
| K6J87_RS26890 (TUM12127_51840) | 92713..93550 | + | 838 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J87_RS26895 (TUM12127_51850) | 93673..94005 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J87_RS26900 (TUM12127_51860) | 94300..94887 | - | 588 | WP_221281830.1 | IS256 family transposase IS406 | Transposase |
| K6J87_RS26905 (TUM12127_51870) | 95203..96181 | - | 979 | Protein_106 | IS5 family transposase IS5D | Transposase |
| K6J87_RS26910 (TUM12127_51880) | 96287..96990 | - | 704 | Protein_107 | IS6 family transposase IS15DI | Transposase |
| K6J87_RS26915 (TUM12127_51890) | 97104..97880 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6J87_RS26920 (TUM12127_51910) | 98109..99134 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J87_RS26925 | 99209..99496 | + | 288 | Protein_110 | AAC(3) family N-acetyltransferase | - |
| K6J87_RS26930 (TUM12127_51920) | 99556..100308 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J87_RS26935 (TUM12127_51930) | 100370..101251 | + | 882 | Protein_112 | Tn3 family transposase | - |
| K6J87_RS26940 | 101413..101496 | - | 84 | Protein_113 | SOS response-associated peptidase | - |
| K6J87_RS26945 (TUM12127_51940) | 102361..102636 | + | 276 | Protein_114 | Phospholipase D | VF |
| K6J87_RS26950 (TUM12127_51950) | 102809..103123 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J87_RS26955 (TUM12127_51960) | 103378..103734 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J87_RS26960 (TUM12127_51970) | 103724..104125 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J87_RS26965 (TUM12127_51980) | 104122..104412 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J87_RS26970 (TUM12127_51990) | 104476..104874 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J87_RS26975 (TUM12127_52000) | 104874..108110 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J87_RS26980 (TUM12127_52010) | 108110..109639 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J87_RS26985 (TUM12127_52020) | 109641..110057 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J87_RS26990 (TUM12127_52030) | 110613..111002 | + | 390 | WP_221281831.1 | plasmid stabilization protein StbA | - |
| K6J87_RS26995 (TUM12127_52040) | 111011..111727 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J87_RS27000 (TUM12127_52050) | 111729..111971 | + | 243 | WP_228740596.1 | hypothetical protein | - |
| K6J87_RS27005 | 112300..112635 | + | 336 | WP_228740597.1 | hypothetical protein | - |
| K6J87_RS27480 | 113104..113282 | - | 179 | Protein_127 | protein CcgAI | - |
| K6J87_RS27010 (TUM12127_52060) | 114114..114625 | - | 512 | Protein_128 | antirestriction protein ArdA | - |
| K6J87_RS27485 (TUM12127_52070) | 116175..116309 | - | 135 | WP_267461052.1 | hypothetical protein | - |
| K6J87_RS27020 (TUM12127_52080) | 116521..116805 | - | 285 | WP_221277214.1 | protein CcgC | - |
| K6J87_RS27025 (TUM12127_52090) | 117231..117527 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J87_RS27030 (TUM12127_52100) | 118412..118651 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J87_RS27035 (TUM12127_52110) | 118661..119065 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J87_RS27040 (TUM12127_52120) | 119123..119548 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J87_RS27045 (TUM12127_52130) | 119964..120404 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J87_RS27050 (TUM12127_52140) | 120392..121657 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J87_RS27055 (TUM12127_52150) | 121808..122599 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J87_RS27060 (TUM12127_52160) | 122614..122955 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|