MGE detailed information
MGE type: Conjugative plasmid MGE length: 97234 bp
Accession: NZ_AP023220 Location: 1..97234 Organism: Escherichia coli strain M505 Replicon: plasmid pM505-NDM5
Accession: NZ_AP023220 Location: 1..97234 Organism: Escherichia coli strain M505 Replicon: plasmid pM505-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EPG46_RS23155 () | 20..247 | - | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| EPG46_RS23160 () | 384..1055 | - | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| EPG46_RS23165 () | 1249..1632 | - | 384 | WP_001354030.1 | relaxosome protein TraM | - |
| EPG46_RS23170 () | 1955..2557 | + | 603 | WP_000243713.1 | transglycosylase SLT domain-containing protein | - |
| EPG46_RS23175 () | 2854..3675 | - | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| EPG46_RS23180 () | 3786..4082 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| EPG46_RS23185 () | 4382..4759 | + | 378 | Protein_6 | hypothetical protein | - |
| EPG46_RS23190 () | 4997..5155 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 5199..5423 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 5199..5423 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 5199..5423 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 5199..5423 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| EPG46_RS23195 () | 5235..5414 | + | 180 | WP_001309233.1 | hypothetical protein | - |
| EPG46_RS23200 () | 5435..6154 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| EPG46_RS23205 () | 6151..6585 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| EPG46_RS23210 () | 6654..8677 | - | 2024 | Protein_11 | ParB/RepB/Spo0J family partition protein | - |
| EPG46_RS23215 () | 8738..8971 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| EPG46_RS23220 () | 9029..9556 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| EPG46_RS23225 () | 9865..10327 | + | 463 | Protein_14 | hypothetical protein | - |
| EPG46_RS23230 () | 10413..10976 | - | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| EPG46_RS23235 () | 11023..12384 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| EPG46_RS23240 () | 12436..12666 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| EPG46_RS23245 () | 14066..15733 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| EPG46_RS23250 () | 16047..16238 | - | 192 | WP_039021874.1 | hypothetical protein | - |
| EPG46_RS23255 () | 16235..16657 | - | 423 | WP_000271684.1 | DUF1380 family protein | - |
| EPG46_RS23260 () | 16704..17006 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| EPG46_RS23265 () | 17489..18259 | - | 771 | WP_001006207.1 | hypothetical protein | - |
| EPG46_RS23270 () | 18304..18738 | - | 435 | WP_000274504.1 | DUF1380 family protein | - |
| EPG46_RS23275 () | 18751..18972 | - | 222 | WP_001104902.1 | hypothetical protein | - |
| EPG46_RS23280 () | 18973..19656 | - | 684 | WP_000085889.1 | DNA methylase | - |
| EPG46_RS23285 () | 19733..20041 | - | 309 | WP_039021875.1 | hypothetical protein | - |
| EPG46_RS23290 () | 20173..21135 | + | 963 | WP_000959875.1 | plasmid segregation protein ParM | - |
| EPG46_RS23295 () | 21138..21488 | + | 351 | WP_001430247.1 | plasmid partitioning/stability family protein | - |
| EPG46_RS23300 () | 21597..22059 | + | 463 | Protein_29 | hypothetical protein | - |
| EPG46_RS23305 () | 22284..23285 | - | 1002 | WP_000138753.1 | DUF4238 domain-containing protein | - |
| EPG46_RS23310 () | 23588..26263 | + | 2676 | WP_015059139.1 | hypothetical protein | - |
| EPG46_RS23315 () | 26435..26602 | + | 168 | WP_001430249.1 | hypothetical protein | - |
| EPG46_RS23320 () | 26609..26778 | - | 170 | Protein_33 | resolvase | - |
| EPG46_RS23325 () | 26774..27658 | - | 885 | WP_001345827.1 | hypothetical protein | - |
| EPG46_RS23330 () | 27727..29241 | - | 1515 | Protein_35 | Tn3-like element TnAs1 family transposase | - |
| EPG46_RS23335 () | 29307..30011 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| EPG46_RS23340 () | 30066..30931 | - | 866 | Protein_37 | class 1 integron integrase IntI1 | - |
| EPG46_RS23345 () | 31076..31573 | + | 498 | WP_001083725.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | - |
| EPG46_RS23350 () | 31685..31975 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| EPG46_RS23355 () | 31981..32772 | + | 792 | WP_001206356.1 | ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2 | - |
| EPG46_RS23360 () | 32936..33283 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| EPG46_RS23365 () | 33277..34116 | + | 840 | WP_000259031.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | - |
| EPG46_RS23370 () | 34521..36062 | + | 1542 | WP_000050481.1 | IS91 family transposase | - |
| EPG46_RS23375 () | 36375..37406 | + | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| EPG46_RS23380 () | 37417..38055 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| EPG46_RS23385 () | 38060..38425 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| EPG46_RS23390 () | 38429..39241 | - | 813 | WP_023408309.1 | subclass B1 metallo-beta-lactamase NDM-5 | - |
| EPG46_RS23395 () | 39342..39635 | - | 294 | Protein_48 | IS30 family transposase | - |
| EPG46_RS23400 () | 39800..40504 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| EPG46_RS23405 () | 40556..40771 | + | 216 | Protein_50 | DDE-type integrase/transposase/recombinase | - |
| EPG46_RS23410 () | 40965..41315 | - | 351 | Protein_51 | chaperonin GroEL | - |
| EPG46_RS23415 () | 41378..41926 | + | 549 | WP_014342204.1 | cation:proton antiporter | - |
| EPG46_RS23420 () | 42007..42762 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase RmtB1 | - |
| EPG46_RS23425 () | 42932..43793 | - | 862 | Protein_54 | class A broad-spectrum beta-lactamase TEM-1 | - |
| EPG46_RS23430 () | 43976..44533 | - | 558 | WP_001235713.1 | recombinase family protein | - |
| EPG46_RS23435 () | 44835..45599 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| EPG46_RS23440 () | 45787..46371 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| EPG46_RS23445 () | 46371..47609 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| EPG46_RS23450 () | 47606..48520 | - | 915 | WP_023063803.1 | Mph(A) family macrolide 2'-phosphotransferase | - |
| EPG46_RS23455 () | 48642..49346 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| EPG46_RS23460 () | 49481..49576 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| EPG46_RS23465 () | 49702..50439 | + | 738 | WP_013362818.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | - |
| EPG46_RS23470 () | 50384..50554 | + | 171 | WP_170852050.1 | rRNA adenine methyltransferase | - |
| EPG46_RS23475 () | 51069..51518 | + | 450 | WP_013362817.1 | hypothetical protein | - |
| EPG46_RS23480 () | 51479..51820 | + | 342 | WP_023909256.1 | chaperonin | - |
| EPG46_RS23485 () | 52047..53528 | + | 1482 | WP_024210412.1 | IS91 family transposase | - |
| EPG46_RS23490 () | 53540..54260 | + | 721 | Protein_67 | IS6-like element IS26 family transposase | - |
| EPG46_RS23495 () | 54313..54858 | + | 546 | Protein_68 | Tn3 family transposase | - |
| EPG46_RS23500 () | 54894..55310 | - | 417 | Protein_69 | IS1 family transposase | - |
| EPG46_RS23505 () | 55559..55960 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| EPG46_RS23510 () | 55893..56150 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| EPG46_RS23515 () | 56244..56897 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| EPG46_RS23520 () | 57841..58698 | - | 858 | WP_060591631.1 | incFII family plasmid replication initiator RepA | - |
| EPG46_RS23525 () | 58691..58765 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| EPG46_RS23530 () | 59003..59257 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| EPG46_RS23535 () | 59497..60087 | - | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| EPG46_RS23540 () | 60125..60334 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| EPG46_RS23545 () | 60380..60841 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| EPG46_RS23555 () | 61086..61298 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| EPG46_RS23560 () | 61427..61987 | - | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| EPG46_RS23565 () | 62090..62950 | - | 861 | WP_000704523.1 | alpha/beta hydrolase | - |
| EPG46_RS23570 () | 63009..63755 | - | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| EPG46_RS23575 () | 63775..69045 | - | 5271 | WP_000948354.1 | conjugative transfer relaxase/helicase TraI | - |
| EPG46_RS23580 () | 69045..70970 | - | 1926 | Protein_84 | type IV conjugative transfer system coupling protein TraD | - |
| EPG46_RS23585 () | 71166..72708 | + | 1543 | Protein_85 | IS21-like element ISEc12 family transposase | - |
| EPG46_RS23590 () | 72723..73471 | + | 749 | Protein_86 | IS21-like element ISEc12 family helper ATPase IstB | - |
| EPG46_RS23595 () | 73557..73904 | - | 348 | Protein_87 | conjugal transfer protein TraD | - |
| EPG46_RS23600 () | 73955..74692 | - | 738 | WP_000199905.1 | hypothetical protein | - |
| EPG46_RS23605 () | 74895..75626 | - | 732 | WP_000782451.1 | complement resistance protein TraT | - |
| EPG46_RS23610 () | 75675..76160 | - | 486 | WP_000605870.1 | hypothetical protein | - |
| EPG46_RS23615 () | 76176..78998 | - | 2823 | WP_001007039.1 | conjugal transfer mating pair stabilization protein TraG | - |
| EPG46_RS23620 () | 78995..80368 | - | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| EPG46_RS23625 () | 80355..80780 | - | 426 | WP_001444237.1 | F-type conjugal transfer protein TrbF | - |
| EPG46_RS23630 () | 80728..81075 | - | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| EPG46_RS23635 () | 81005..81550 | - | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EPG46_RS23640 () | 81537..81821 | - | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| EPG46_RS23645 () | 81940..82284 | - | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| EPG46_RS23650 () | 82298..83042 | - | 745 | Protein_98 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EPG46_RS23655 () | 83035..83292 | - | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| EPG46_RS23660 () | 83319..85169 | - | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EPG46_RS23665 () | 85166..85806 | - | 641 | Protein_101 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EPG46_RS23670 () | 85815..86120 | - | 306 | WP_000224416.1 | hypothetical protein | - |
| EPG46_RS23675 () | 86150..87142 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| EPG46_RS23680 () | 87139..87771 | - | 633 | WP_001203728.1 | type-F conjugative transfer system protein TraW | - |
| EPG46_RS23685 () | 87768..88154 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| EPG46_RS23690 () | 88151..90781 | - | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| EPG46_RS23695 () | 90907..91254 | - | 348 | WP_000836682.1 | hypothetical protein | - |
| EPG46_RS23700 () | 91282..91500 | - | 219 | WP_000556745.1 | hypothetical protein | - |
| EPG46_RS23705 () | 91580..92056 | - | 477 | WP_000549587.1 | hypothetical protein | - |
| EPG46_RS23710 () | 92049..92270 | - | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| EPG46_RS23715 () | 92405..92920 | - | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EPG46_RS23720 () | 92917..93285 | - | 369 | WP_001315561.1 | conjugal transfer protein TrbD | - |
| EPG46_RS23725 () | 93224..93811 | - | 588 | WP_001444176.1 | conjugal transfer protein TraP | - |
| EPG46_RS23730 () | 93780..95231 | - | 1452 | WP_000146675.1 | conjugal transfer protein TraB | - |
| EPG46_RS23735 () | 95231..95935 | - | 705 | WP_148998276.1 | type-F conjugative transfer system secretin TraK | - |
| EPG46_RS23740 () | 95946..96513 | - | 568 | Protein_116 | type IV conjugative transfer system protein TraE | - |
| EPG46_RS23745 () | 96535..96850 | - | 316 | Protein_117 | type IV conjugative transfer system protein TraL | - |
| EPG46_RS23750 () | 96865..97224 | - | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|