MGE detailed information
MGE type: Conjugative plasmid MGE length: 93398 bp
Accession: NZ_AP022097 Location: 1..93398 Organism: Escherichia coli strain WP4-S18-ESBL-08 Replicon: plasmid pWP4-S18-ESBL-08_2
Accession: NZ_AP022097 Location: 1..93398 Organism: Escherichia coli strain WP4-S18-ESBL-08 Replicon: plasmid pWP4-S18-ESBL-08_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R08_RS24440 () | 334..594 | + | 261 | WP_072118300.1 | prepilin | - |
| H7R08_RS24445 () | 591..2015 | - | 1425 | WP_061684464.1 | hypothetical protein | VF |
| H7R08_RS24450 () | 2015..2671 | - | 657 | WP_001193551.1 | hypothetical protein | VF |
| H7R08_RS24455 () | 2656..3216 | - | 561 | WP_000014005.1 | hypothetical protein | VF |
| H7R08_RS24460 () | 3226..3840 | - | 615 | WP_000908228.1 | hypothetical protein | VF |
| H7R08_RS24465 () | 3857..4942 | - | 1086 | WP_001208803.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| H7R08_RS24470 () | 4955..6508 | - | 1554 | WP_000362204.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| H7R08_RS24475 () | 6519..6971 | - | 453 | WP_001247333.1 | hypothetical protein | VF |
| H7R08_RS24480 () | 6958..8253 | - | 1296 | WP_000752776.1 | type 4b pilus protein PilO2 | - |
| H7R08_RS24485 () | 8246..9928 | - | 1683 | WP_000748143.1 | Outer membrane lipoprotein BfpB | VF |
| H7R08_RS24490 () | 9942..10379 | - | 438 | WP_000539811.1 | hypothetical protein | VF |
| H7R08_RS24495 () | 10379..11446 | - | 1068 | WP_021513968.1 | hypothetical protein | VF |
| H7R08_RS24500 () | 12198..12452 | - | 255 | WP_001136187.1 | PilI type IV pilus biogenesis protein | - |
| H7R08_RS24505 () | 12624..13307 | - | 684 | WP_000213859.1 | conjugal transfer protein TraC | - |
| H7R08_RS24510 () | 13561..14094 | - | 534 | WP_001372168.1 | transcription termination factor NusG | - |
| H7R08_RS24515 () | 14536..14823 | - | 288 | WP_000074849.1 | conjugal transfer protein TraA | - |
| H7R08_RS24520 () | 14741..15004 | - | 264 | WP_001324596.1 | ash family protein | - |
| H7R08_RS24525 () | 15977..17008 | + | 1032 | WP_000907852.1 | replication initiation protein | - |
| H7R08_RS24530 () | 17912..18196 | + | 285 | WP_001178087.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| H7R08_RS24535 () | 18196..18471 | + | 276 | WP_000421259.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| H7R08_RS24540 () | 18577..18858 | + | 282 | WP_001105066.1 | hypothetical protein | - |
| H7R08_RS24545 () | 19050..19316 | - | 267 | WP_000627832.1 | hypothetical protein | - |
| H7R08_RS24550 () | 19316..19810 | - | 495 | WP_015058884.1 | hypothetical protein | - |
| H7R08_RS24555 () | 19866..20468 | - | 603 | WP_061671620.1 | proQ/FINO family protein | - |
| H7R08_RS24560 () | 20822..21253 | + | 432 | Protein_24 | hypothetical protein | - |
| H7R08_RS24570 () | 22839..23504 | + | 666 | WP_000448921.1 | hypothetical protein | - |
| H7R08_RS24575 () | 23783..25663 | + | 1881 | WP_061671619.1 | colicin | - |
| H7R08_RS24580 () | 25681..26028 | - | 348 | WP_016232722.1 | hypothetical protein | - |
| H7R08_RS24585 () | 26147..26494 | + | 348 | WP_000142441.1 | hypothetical protein | - |
| H7R08_RS24590 () | 26512..27102 | - | 591 | WP_000194574.1 | hypothetical protein | - |
| H7R08_RS24595 () | 27102..27359 | - | 258 | WP_000343085.1 | hypothetical protein | - |
| H7R08_RS24600 () | 27928..28341 | + | 414 | WP_000465036.1 | hypothetical protein | - |
| H7R08_RS24605 () | 28343..29122 | + | 780 | WP_001199724.1 | site-specific integrase | - |
| H7R08_RS24610 () | 29302..29946 | + | 645 | WP_001144036.1 | ParA family protein | - |
| H7R08_RS24615 () | 30033..30341 | + | 309 | WP_000030199.1 | hypothetical protein | - |
| H7R08_RS24620 () | 30755..31735 | + | 981 | WP_000688514.1 | plasmid segregation protein ParM | - |
| H7R08_RS24625 () | 31728..32144 | + | 417 | WP_001278818.1 | plasmid partitioning/stability family protein | - |
| H7R08_RS24630 () | 32146..32775 | - | 630 | Protein_38 | DUF4113 domain-containing protein | - |
| H7R08_RS24635 () | 32827..33531 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H7R08_RS24640 () | 33597..34523 | - | 927 | Protein_40 | IS4 family transposase IS10R | Transposase |
| H7R08_RS24645 () | 34742..35617 | + | 876 | WP_032489598.1 | Beta-lactamase CTX-M-97 | ARG |
| H7R08_RS24650 () | 35772..36476 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H7R08_RS24655 () | 36539..37180 | + | 642 | Protein_43 | DUF1281 domain-containing protein | - |
| H7R08_RS24660 () | 37184..37489 | + | 306 | WP_015058890.1 | hypothetical protein | - |
| H7R08_RS24665 () | 37565..38248 | + | 684 | WP_000086160.1 | DNA methylase | - |
| H7R08_RS24670 () | 38249..38470 | + | 222 | WP_021560304.1 | hypothetical protein | - |
| H7R08_RS24675 () | 38483..38917 | + | 435 | WP_061671618.1 | DUF1380 family protein | - |
| H7R08_RS24680 () | 38963..39739 | + | 777 | WP_061671617.1 | hypothetical protein | - |
| H7R08_RS24685 () | 40273..40575 | + | 303 | WP_075207376.1 | antirestriction protein | - |
| H7R08_RS24690 () | 40622..41044 | + | 423 | WP_061671614.1 | DUF1380 family protein | - |
| H7R08_RS24695 () | 41041..41232 | + | 192 | WP_001697954.1 | hypothetical protein | - |
| H7R08_RS24700 () | 41303..41617 | + | 315 | WP_024199621.1 | hypothetical protein | - |
| H7R08_RS24705 () | 42001..42528 | + | 528 | WP_053264372.1 | single-stranded DNA-binding protein | - |
| H7R08_RS24710 () | 42585..42818 | + | 234 | WP_061671613.1 | DUF905 domain-containing protein | - |
| H7R08_RS24715 () | 42880..44838 | + | 1959 | WP_061671612.1 | ParB/RepB/Spo0J family partition protein | - |
| H7R08_RS24720 () | 44893..45327 | + | 435 | WP_000845900.1 | conjugation system SOS inhibitor PsiB | - |
| H7R08_RS24725 () | 45324..46043 | + | 720 | WP_001276261.1 | plasmid SOS inhibition protein A | - |
| H7R08_RS24730 () | 46173..46574 | + | 402 | Protein_58 | IS200-IS605 family transposase ISEc46 | Transposase |
| H7R08_RS24735 () | 46658..47404 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| H7R08_RS24740 () | 47419..48960 | - | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| H7R08_RS24745 () | 49128..49934 | + | 807 | WP_182913418.1 | IS200-IS605 family transposase ISEc46 | Transposase |
| H7R08_RS24750 () | 50382..50882 | + | 501 | WP_000117622.1 | antirestriction protein ArdA | - |
| H7R08_RS24755 () | 51611..52045 | + | 435 | WP_000218863.1 | hypothetical protein | - |
| H7R08_RS24760 () | 52138..52404 | + | 267 | WP_001247862.1 | hypothetical protein | - |
| H7R08_RS24765 () | 52469..53359 | + | 891 | WP_000038399.1 | Recombination-promoting nuclease RpnA | VF |
| H7R08_RS24770 () | 53422..53616 | + | 195 | WP_061671610.1 | hypothetical protein | VF |
| H7R08_RS24775 () | 53647..53898 | - | 252 | WP_000148286.1 | helix-turn-helix domain-containing protein | - |
| H7R08_RS24780 () | 53932..54129 | - | 198 | WP_052975742.1 | hypothetical protein | - |
| H7R08_RS24785 () | 54479..55327 | + | 849 | WP_021513954.1 | DUF4942 domain-containing protein | - |
| H7R08_RS24790 () | 55413..55748 | - | 336 | WP_000157095.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| H7R08_RS24795 () | 55982..56314 | + | 333 | WP_001283947.1 | IncI1-type relaxosome accessory protein NikA | - |
| H7R08_RS24800 () | 56325..59024 | + | 2700 | WP_001306778.1 | Protein TraI | Relaxase |
| H7R08_RS24805 () | 59061..61352 | - | 2292 | WP_024255997.1 | hypothetical protein | - |
| H7R08_RS24810 () | 61345..62415 | - | 1071 | WP_000151583.1 | IncI1-type conjugal transfer protein TrbB | - |
| H7R08_RS24815 () | 62434..63642 | - | 1209 | WP_000121273.1 | IncI1-type conjugal transfer protein TrbA | - |
| - () | 63822..63884 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63822..63884 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63822..63884 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63822..63884 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| H7R08_RS24820 () | 63934..64086 | + | 153 | WP_001303307.1 | Hok/Gef family protein | Toxin Detail |
| H7R08_RS24825 () | 64158..64409 | - | 252 | WP_001291965.1 | hypothetical protein | - |
| - () | 64796..64847 | - | 52 | NuclAT_1 | - | - |
| - () | 64796..64847 | - | 52 | NuclAT_1 | - | - |
| - () | 64796..64847 | - | 52 | NuclAT_1 | - | - |
| - () | 64796..64847 | - | 52 | NuclAT_1 | - | - |
| H7R08_RS24830 () | 65333..65509 | - | 177 | WP_001054900.1 | hypothetical protein | - |
| H7R08_RS24835 () | 65901..66110 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| H7R08_RS24840 () | 66182..66844 | - | 663 | WP_000644794.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| H7R08_RS24845 () | 66915..69083 | - | 2169 | WP_000698368.1 | DotA/TraY family protein | - |
| H7R08_RS24850 () | 69180..69764 | - | 585 | WP_001037985.1 | IncI1-type conjugal transfer protein TraX | - |
| H7R08_RS24855 () | 69793..70995 | - | 1203 | WP_001189156.1 | IncI1-type conjugal transfer protein TraW | - |
| H7R08_RS24860 () | 70962..71576 | - | 615 | WP_000337400.1 | IncI1-type conjugal transfer protein TraV | - |
| H7R08_RS24865 () | 71576..74620 | - | 3045 | WP_001024780.1 | IncI1-type conjugal transfer protein TraU | - |
| H7R08_RS24870 () | 74710..75510 | - | 801 | WP_001164788.1 | IncI1-type conjugal transfer protein TraT | - |
| H7R08_RS24875 () | 75494..75682 | - | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| H7R08_RS24880 () | 75746..76150 | - | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| H7R08_RS24885 () | 76201..76728 | - | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| H7R08_RS24890 () | 76728..77432 | - | 705 | WP_000801919.1 | IncI1-type conjugal transfer protein TraP | - |
| H7R08_RS24895 () | 77432..78721 | - | 1290 | WP_033544219.1 | conjugal transfer protein TraO | - |
| H7R08_RS24900 () | 78724..79707 | - | 984 | WP_021513963.1 | hypothetical protein | VF |
| H7R08_RS24905 () | 79718..80410 | - | 693 | WP_000138552.1 | DotI/IcmL family type IV secretion protein | - |
| H7R08_RS24910 () | 80407..80754 | - | 348 | WP_001055900.1 | conjugal transfer protein | - |
| H7R08_RS24915 () | 80772..84539 | - | 3768 | WP_006855639.1 | DNA primase SogL | - |
| H7R08_RS24920 () | 84629..85180 | - | 552 | WP_000014584.1 | Phospholipase D | VF |
| H7R08_RS24925 () | 85195..85485 | - | 291 | WP_001299214.1 | hypothetical protein | - |
| H7R08_RS24930 () | 85482..86630 | - | 1149 | WP_001024976.1 | putative protein YggR | VF |
| H7R08_RS24935 () | 86627..87445 | - | 819 | WP_000646097.1 | hypothetical protein | VF |
| H7R08_RS24940 () | 87442..87900 | - | 459 | WP_001079808.1 | hypothetical protein | VF |
| H7R08_RS24945 () | 88295..88879 | - | 585 | WP_061671621.1 | histidine phosphatase family protein | - |
| H7R08_RS24950 () | 88939..90141 | - | 1203 | WP_000976357.1 | conjugal transfer protein TraF | - |
| H7R08_RS24955 () | 90227..91051 | - | 825 | WP_015058912.1 | conjugal transfer protein TraE | - |
| H7R08_RS24960 () | 91202..92356 | - | 1155 | WP_001139955.1 | integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|