MGE detailed information
MGE type: Conjugative plasmid MGE length: 148598 bp
Accession: NZ_AP022045 Location: 1..148598 Organism: Escherichia coli strain WP4-S17-ESBL-03 Replicon: plasmid pWP4-S17-ESBL-03_1
Accession: NZ_AP022045 Location: 1..148598 Organism: Escherichia coli strain WP4-S17-ESBL-03 Replicon: plasmid pWP4-S17-ESBL-03_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R12_RS24510 () | 101..331 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| H7R12_RS24515 () | 383..1744 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| H7R12_RS24520 () | 1792..2355 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| H7R12_RS24525 () | 2381..2665 | + | 285 | WP_155953315.1 | hypothetical protein | - |
| H7R12_RS24530 () | 2780..4447 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| H7R12_RS24535 () | 5651..6190 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| H7R12_RS24540 () | 6253..6486 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| H7R12_RS24545 () | 6552..8510 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| H7R12_RS24550 () | 8565..8999 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| H7R12_RS24555 () | 8996..9715 | + | 720 | WP_049027643.1 | plasmid SOS inhibition protein A | - |
| H7R12_RS24560 () | 9712..10026 | + | 315 | WP_000872086.1 | hypothetical protein | - |
| - () | 9983..10168 | + | 186 | NuclAT_0 | - | - |
| - () | 9983..10168 | + | 186 | NuclAT_0 | - | - |
| - () | 9983..10168 | + | 186 | NuclAT_0 | - | - |
| - () | 9983..10168 | + | 186 | NuclAT_0 | - | - |
| H7R12_RS24565 () | 10234..10395 | + | 162 | WP_000775238.1 | type I toxin-antitoxin system Hok family toxin | - |
| H7R12_RS24570 () | 10633..10945 | - | 313 | Protein_12 | hypothetical protein | - |
| H7R12_RS24575 () | 11241..11564 | + | 324 | WP_001528573.1 | hypothetical protein | - |
| H7R12_RS24580 () | 11623..11865 | + | 243 | WP_000540588.1 | hypothetical protein | - |
| H7R12_RS24585 () | 12065..12241 | - | 177 | Protein_15 | pilus protein | - |
| H7R12_RS24590 () | 12354..13166 | - | 813 | WP_174243809.1 | HNH endonuclease | - |
| H7R12_RS24595 () | 13351..13642 | - | 292 | Protein_17 | reverse transcriptase | - |
| H7R12_RS24600 () | 13736..14020 | - | 285 | Protein_18 | reverse transcriptase N-terminal domain-containing protein | - |
| H7R12_RS24605 () | 15222..15518 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| H7R12_RS24610 () | 15633..16454 | + | 822 | WP_001528640.1 | DUF945 domain-containing protein | - |
| H7R12_RS24615 () | 16751..17353 | - | 603 | WP_077634803.1 | hypothetical protein | VF |
| H7R12_RS24620 () | 17674..18057 | + | 384 | WP_001151538.1 | relaxosome protein TraM | - |
| H7R12_RS24625 () | 18244..18933 | + | 690 | WP_113235258.1 | conjugal transfer transcriptional regulator TraJ | - |
| H7R12_RS24630 () | 19032..19427 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| H7R12_RS24635 () | 19460..19822 | + | 363 | WP_001673167.1 | type IV conjugative transfer system pilin TraA | - |
| H7R12_RS24640 () | 19837..20148 | + | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| H7R12_RS24645 () | 20170..20736 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| H7R12_RS24650 () | 20723..21451 | + | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| H7R12_RS24655 () | 21451..22902 | + | 1452 | WP_042028686.1 | conjugal transfer protein TraB | - |
| H7R12_RS24660 () | 22871..23458 | + | 588 | WP_001309238.1 | conjugal transfer protein TraP | - |
| H7R12_RS24665 () | 23412..23762 | + | 351 | WP_071586941.1 | conjugal transfer protein TrbD | - |
| H7R12_RS24670 () | 23762..24277 | + | 516 | WP_000809872.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R12_RS24675 () | 24412..24633 | + | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| H7R12_RS24680 () | 24626..25039 | + | 414 | WP_000549574.1 | hypothetical protein | - |
| H7R12_RS24685 () | 25032..25505 | + | 474 | WP_033558861.1 | hypothetical protein | - |
| H7R12_RS24690 () | 25585..25803 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| H7R12_RS24695 () | 25831..26178 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| H7R12_RS24700 () | 26304..28934 | + | 2631 | WP_021526637.1 | type IV secretion system protein TraC | - |
| H7R12_RS24705 () | 28931..29317 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| H7R12_RS24710 () | 29314..29946 | + | 633 | WP_021526638.1 | type-F conjugative transfer system protein TraW | - |
| H7R12_RS24715 () | 29943..30935 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R12_RS24720 () | 30965..31270 | + | 306 | WP_000224418.1 | hypothetical protein | - |
| H7R12_RS24725 () | 31279..31917 | + | 639 | WP_001080251.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R12_RS24730 () | 31914..33764 | + | 1851 | WP_042089613.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R12_RS24735 () | 33791..34048 | + | 258 | WP_000864309.1 | conjugal transfer protein TrbE | - |
| H7R12_RS24740 () | 34041..34784 | + | 744 | WP_001030385.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R12_RS24745 () | 34798..35139 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| H7R12_RS24750 () | 35120..35455 | - | 336 | WP_000736414.1 | hypothetical protein | - |
| H7R12_RS24755 () | 35536..35820 | + | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R12_RS24760 () | 35807..36352 | + | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R12_RS24765 () | 36282..36656 | + | 375 | WP_071838165.1 | P-type conjugative transfer protein TrbJ | - |
| H7R12_RS24770 () | 36577..37002 | + | 426 | WP_072020685.1 | F-type conjugal transfer protein TrbF | - |
| H7R12_RS24775 () | 36989..38362 | + | 1374 | WP_001673176.1 | conjugal transfer protein TraH | - |
| H7R12_RS24780 () | 38359..41181 | + | 2823 | WP_049027720.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R12_RS24785 () | 41196..41699 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| H7R12_RS24790 () | 41731..42462 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| H7R12_RS24795 () | 42665..43402 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| H7R12_RS24800 () | 43453..45714 | + | 2262 | WP_042019658.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7R12_RS24805 () | 45714..50984 | + | 5271 | WP_182913586.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7R12_RS24810 () | 51004..51750 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| H7R12_RS24815 () | 51809..52669 | + | 861 | WP_000704523.1 | putative protein YcjY | VF |
| H7R12_RS24820 () | 52772..53332 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| H7R12_RS24825 () | 53461..53673 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| H7R12_RS24830 () | 53918..54379 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| H7R12_RS24835 () | 54425..54634 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| H7R12_RS24840 () | 54672..55262 | + | 591 | WP_001526018.1 | DUF2726 domain-containing protein | - |
| H7R12_RS24845 () | 55502..55759 | + | 258 | WP_000083826.1 | replication regulatory protein RepA | - |
| H7R12_RS24850 () | 55995..56069 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| H7R12_RS24855 () | 56062..56919 | + | 858 | WP_001528607.1 | incFII family plasmid replication initiator RepA | - |
| H7R12_RS24860 () | 57858..58511 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| H7R12_RS24865 () | 58604..58861 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H7R12_RS24870 () | 58794..59195 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H7R12_RS24875 () | 59444..59859 | + | 416 | Protein_73 | IS1 family transposase | - |
| H7R12_RS24880 () | 59895..60440 | - | 546 | Protein_74 | Tn3 family transposase TnpA_Tn3 | Transposase |
| H7R12_RS24885 () | 60506..61210 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H7R12_RS24890 () | 61524..62399 | + | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| H7R12_RS24895 () | 62434..62796 | + | 363 | Protein_77 | IS5 family transposase IS903B | Transposase |
| H7R12_RS24900 () | 62856..63560 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H7R12_RS24905 () | 63613..63945 | + | 333 | Protein_79 | EamA family transporter | - |
| H7R12_RS24910 () | 63977..65176 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| H7R12_RS24915 () | 65282..65908 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| H7R12_RS24920 () | 66029..66733 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H7R12_RS24925 () | 66786..67712 | + | 927 | Protein_83 | type II site-specific deoxyribonuclease | - |
| H7R12_RS24930 () | 67746..69149 | - | 1404 | WP_072094655.1 | DNA cytosine methyltransferase | - |
| H7R12_RS24935 () | 69278..69550 | + | 273 | Protein_85 | IS1 family transposase IS1X2 | Transposase |
| H7R12_RS24940 () | 69561..69767 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| H7R12_RS24945 () | 69772..70413 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| H7R12_RS24950 () | 70469..70780 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| H7R12_RS24955 () | 70816..71130 | - | 315 | WP_016338363.1 | KikA | - |
| H7R12_RS24960 () | 71127..71471 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| H7R12_RS24965 () | 71487..71837 | - | 351 | WP_071562618.1 | H-NS histone family protein | - |
| H7R12_RS24970 () | 71901..72638 | + | 738 | WP_109547639.1 | Type IV secretion system protein virB1 | VF |
| H7R12_RS24975 () | 72647..72928 | + | 282 | WP_016338364.1 | hypothetical protein | - |
| H7R12_RS24980 () | 72938..73231 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| H7R12_RS24985 () | 73281..73598 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| H7R12_RS24990 () | 73598..75808 | + | 2211 | Protein_96 | Type IV secretion system protein virB4 | VF |
| H7R12_RS24995 () | 75874..76578 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H7R12_RS25000 () | 76630..77208 | - | 579 | Protein_98 | iron permease | - |
| H7R12_RS25005 () | 77555..78370 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| H7R12_RS25010 () | 78553..79059 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| H7R12_RS25015 () | 79049..79207 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| H7R12_RS25020 () | 79670..80367 | + | 698 | Protein_102 | IS1 family transposase IS1R | Transposase |
| H7R12_RS25025 () | 80382..80600 | + | 219 | Protein_103 | IS4 family transposase | - |
| H7R12_RS25030 () | 80650..81354 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H7R12_RS25035 () | 81413..82648 | + | 1236 | Protein_105 | FTR1 family iron permease | - |
| H7R12_RS25040 () | 82689..83216 | + | 528 | WP_000178050.1 | iron transporter | - |
| H7R12_RS25045 () | 83320..84699 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| H7R12_RS25050 () | 84702..85985 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| H7R12_RS25055 () | 85975..87105 | + | 1131 | WP_000729218.1 | ABC transporter permease | - |
| H7R12_RS25060 () | 87110..87805 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| H7R12_RS25065 () | 87792..88277 | + | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| H7R12_RS25070 () | 88302..88787 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| H7R12_RS25075 () | 88909..89542 | + | 634 | Protein_113 | histidine-type phosphatase | - |
| H7R12_RS25080 () | 89692..89865 | - | 174 | Protein_114 | IS5 family transposase ISKpn26 | Transposase |
| H7R12_RS25085 () | 89866..90180 | - | 315 | Protein_115 | IS5 family transposase ISKpn26 | Transposase |
| H7R12_RS25090 () | 90853..91592 | - | 740 | Protein_116 | IS3 family transposase IS629 | Transposase |
| H7R12_RS25095 () | 91694..91954 | + | 261 | WP_000371882.1 | hypothetical protein | - |
| H7R12_RS25100 () | 91951..92460 | + | 510 | WP_000194542.1 | hypothetical protein | - |
| H7R12_RS25105 () | 92480..92827 | - | 348 | WP_000142452.1 | hypothetical protein | - |
| H7R12_RS25110 () | 92956..93291 | + | 336 | WP_001080732.1 | colicin transporter | - |
| H7R12_RS25115 () | 94743..95429 | + | 687 | Protein_121 | replication initiation protein | - |
| H7R12_RS25120 () | 95761..96636 | + | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| H7R12_RS25125 () | 96644..97420 | + | 777 | WP_000981091.1 | energy transducer TonB | - |
| H7R12_RS25130 () | 97589..99850 | + | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| H7R12_RS25135 () | 99919..101094 | + | 1176 | WP_001020413.1 | putative protein YncE | VF |
| H7R12_RS25140 () | 101617..101922 | - | 306 | Protein_126 | IS91 family transposase ISSbo1 | Transposase |
| H7R12_RS25145 () | 101948..102687 | + | 740 | Protein_127 | IS3 family transposase IS629 | Transposase |
| H7R12_RS25150 () | 103359..104867 | + | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| H7R12_RS25155 () | 104957..105340 | + | 384 | Protein_129 | IS3 family transposase IS629 | Transposase |
| H7R12_RS25160 () | 105369..105773 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| H7R12_RS25165 () | 105770..106117 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| H7R12_RS25170 () | 106166..107111 | + | 946 | Protein_132 | IS66 family transposase ISEc8 | Transposase |
| H7R12_RS25175 () | 107197..108219 | + | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| H7R12_RS25180 () | 108219..108998 | + | 780 | WP_001323403.1 | IS21 family transposase IS100kyp | Transposase |
| H7R12_RS25185 () | 109066..109674 | + | 609 | Protein_135 | IS66 family transposase ISEc22 | Transposase |
| H7R12_RS25190 () | 109737..110528 | - | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| H7R12_RS25195 () | 110535..112505 | - | 1971 | WP_001298664.1 | Hemin receptor | VF |
| H7R12_RS25200 () | 112787..113223 | + | 437 | Protein_138 | IS3 family transposase IS2 | Transposase |
| H7R12_RS25205 () | 113748..114020 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| H7R12_RS25210 () | 114466..114641 | + | 176 | Protein_140 | IS3 family transposase | - |
| H7R12_RS25215 () | 114867..116036 | - | 1170 | WP_001072358.1 | hypothetical protein | - |
| H7R12_RS25220 () | 116403..116591 | + | 189 | WP_001309252.1 | hypothetical protein | - |
| H7R12_RS25225 () | 116712..117452 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| H7R12_RS25230 () | 117737..118714 | - | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| H7R12_RS25235 () | 119500..120231 | + | 732 | WP_001617898.1 | hypothetical protein | - |
| H7R12_RS25240 () | 120600..120848 | - | 249 | Protein_146 | abortive infection family protein | - |
| H7R12_RS25245 () | 120906..121603 | + | 698 | Protein_147 | IS1 family transposase IS1R | Transposase |
| H7R12_RS25250 () | 121619..121948 | + | 330 | Protein_148 | TOBE domain-containing protein | - |
| H7R12_RS25255 () | 122057..122989 | - | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| H7R12_RS25260 () | 122976..124379 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| H7R12_RS25265 () | 124587..125603 | + | 1017 | WP_012372828.1 | IS5 family transposase IS5D | Transposase |
| H7R12_RS25270 () | 125831..126148 | + | 318 | WP_001513659.1 | hypothetical protein | - |
| H7R12_RS25275 () | 126098..126511 | - | 414 | Protein_153 | IS3 family transposase ISLad1 | Transposase |
| H7R12_RS25280 () | 126435..126794 | - | 360 | WP_001513660.1 | hypothetical protein | - |
| H7R12_RS25285 () | 126822..127001 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| H7R12_RS25290 () | 127006..127386 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| H7R12_RS25295 () | 127386..127607 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| H7R12_RS25300 () | 127790..129346 | + | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| H7R12_RS25305 () | 129343..130092 | + | 750 | Protein_159 | restriction endonuclease subunit S | - |
| H7R12_RS25310 () | 130434..131131 | + | 698 | Protein_160 | IS1 family transposase IS1G | Transposase |
| H7R12_RS25315 () | 131268..132200 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| H7R12_RS25320 () | 132204..133199 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| H7R12_RS25325 () | 133907..134125 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H7R12_RS25330 () | 134127..134432 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H7R12_RS25335 () | 134433..135239 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| H7R12_RS25340 () | 136013..136768 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| H7R12_RS25345 () | 137356..138522 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| H7R12_RS25350 () | 138522..139493 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H7R12_RS25355 () | 140360..141262 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| H7R12_RS25360 () | 141266..141570 | + | 305 | Protein_170 | hypothetical protein | - |
| H7R12_RS25365 () | 141647..142330 | + | 684 | WP_000086185.1 | DNA methylase | - |
| H7R12_RS25370 () | 142331..142552 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| H7R12_RS25375 () | 142566..143000 | + | 435 | WP_000274447.1 | DUF1380 family protein | - |
| H7R12_RS25380 () | 143045..143815 | + | 771 | WP_001006242.1 | hypothetical protein | - |
| H7R12_RS25385 () | 144354..144656 | + | 303 | WP_072257078.1 | antirestriction protein | - |
| H7R12_RS25390 () | 144703..145125 | + | 423 | WP_000271722.1 | DUF1380 family protein | - |
| H7R12_RS25395 () | 145122..145313 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| H7R12_RS25400 () | 145633..147300 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|