MGE detailed information
MGE type: Conjugative plasmid MGE length: 158754 bp
Accession: NZ_AP021915 Location: 1..158754 Organism: Escherichia coli strain WP2-W18-CRE-03 Replicon: plasmid pWP2-W18-CRE-03_1
Accession: NZ_AP021915 Location: 1..158754 Organism: Escherichia coli strain WP2-W18-CRE-03 Replicon: plasmid pWP2-W18-CRE-03_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7Q98_RS22785 () | 101..1054 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| H7Q98_RS22790 () | 1487..2596 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| H7Q98_RS22795 () | 2665..3567 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| H7Q98_RS22800 () | 3941..4129 | + | 189 | WP_001324033.1 | hypothetical protein | - |
| H7Q98_RS22805 () | 4250..4990 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| H7Q98_RS22810 () | 5275..6252 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H7Q98_RS22815 () | 6998..7321 | + | 324 | Protein_6 | IS21 family transposase IS21 | Transposase |
| H7Q98_RS22820 () | 7323..7427 | + | 105 | Protein_7 | AAA family ATPase | - |
| H7Q98_RS22825 () | 7488..8001 | + | 514 | Protein_8 | DUF4113 domain-containing protein | - |
| H7Q98_RS22830 () | 8181..8878 | - | 698 | Protein_9 | IS1 family transposase IS1S | Transposase |
| H7Q98_RS22835 () | 9234..10148 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| H7Q98_RS22840 () | 10148..10975 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| H7Q98_RS22845 () | 10972..11829 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| H7Q98_RS22850 () | 11826..12683 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| H7Q98_RS22855 () | 12917..13174 | - | 258 | Protein_14 | Tn3 family transposase | - |
| H7Q98_RS22860 () | 13172..13585 | + | 414 | Protein_15 | phosphopyruvate hydratase | - |
| H7Q98_RS22865 () | 13926..14306 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| H7Q98_RS22870 () | 14686..15879 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| H7Q98_RS22875 () | 16015..17739 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| H7Q98_RS22880 () | 17740..18687 | + | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| H7Q98_RS22885 () | 18687..20429 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| H7Q98_RS22890 () | 20426..21703 | + | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| H7Q98_RS22895 () | 21785..23986 | + | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| H7Q98_RS22900 () | 24471..25168 | + | 698 | Protein_23 | IS1 family transposase IS1S | Transposase |
| H7Q98_RS22905 () | 25468..26634 | + | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| H7Q98_RS22910 () | 26634..27605 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H7Q98_RS22915 () | 28744..28950 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| H7Q98_RS22920 () | 28976..29515 | + | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| H7Q98_RS22925 () | 29583..29816 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| H7Q98_RS22930 () | 29844..30041 | + | 198 | Protein_29 | hypothetical protein | - |
| H7Q98_RS22935 () | 30096..30530 | + | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| H7Q98_RS22940 () | 30527..31246 | + | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| H7Q98_RS22945 () | 31258..31446 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| H7Q98_RS22950 () | 31526..31684 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7Q98_RS22955 () | 32605..32892 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| H7Q98_RS22960 () | 33010..33831 | + | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| H7Q98_RS22965 () | 34128..34730 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| H7Q98_RS22970 () | 35051..35434 | + | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| H7Q98_RS22975 () | 35621..36310 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| H7Q98_RS22980 () | 36409..36804 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| H7Q98_RS22985 () | 36837..37202 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| H7Q98_RS22990 () | 37217..37528 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H7Q98_RS22995 () | 37550..38116 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| H7Q98_RS23000 () | 38127..38831 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| H7Q98_RS23005 () | 38831..40258 | + | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| H7Q98_RS23010 () | 40248..40838 | + | 591 | WP_001376242.1 | conjugal transfer protein TraP | - |
| H7Q98_RS23015 () | 40792..41022 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| H7Q98_RS23020 () | 41034..41285 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H7Q98_RS23025 () | 41282..41797 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7Q98_RS23030 () | 41932..42153 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H7Q98_RS23035 () | 42313..44940 | + | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H7Q98_RS23040 () | 44937..45323 | + | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| H7Q98_RS23045 () | 45320..45952 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| H7Q98_RS23050 () | 45949..46941 | + | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| H7Q98_RS23055 () | 46950..47588 | + | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7Q98_RS23060 () | 47585..49393 | + | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7Q98_RS23065 () | 49420..49677 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| H7Q98_RS23070 () | 49670..50413 | + | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7Q98_RS23075 () | 50429..50776 | + | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| H7Q98_RS23080 () | 50778..51092 | - | 315 | WP_001324103.1 | hypothetical protein | - |
| H7Q98_RS23085 () | 51173..51457 | + | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7Q98_RS23090 () | 51444..51989 | + | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7Q98_RS23095 () | 51919..52260 | + | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| H7Q98_RS23100 () | 52214..52627 | + | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| H7Q98_RS23105 () | 52627..54000 | + | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| H7Q98_RS23110 () | 53997..56819 | + | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7Q98_RS23115 () | 56835..57332 | + | 498 | WP_000605857.1 | entry exclusion protein | - |
| H7Q98_RS23120 () | 57364..58095 | + | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| H7Q98_RS23125 () | 58348..60501 | + | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7Q98_RS23130 () | 60510..60908 | - | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| H7Q98_RS23135 () | 60908..61135 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| H7Q98_RS23140 () | 61217..66487 | + | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7Q98_RS23145 () | 66507..67253 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| H7Q98_RS23150 () | 67312..68172 | + | 861 | WP_000704514.1 | putative protein YcjY | VF |
| H7Q98_RS23155 () | 68275..68835 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| H7Q98_RS23160 () | 68971..69183 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| H7Q98_RS23165 () | 69429..69503 | + | 75 | Protein_76 | endonuclease | - |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| H7Q98_RS23170 () | 69807..70013 | + | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7Q98_RS23175 () | 70297..70554 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| H7Q98_RS23180 () | 70786..70860 | + | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| H7Q98_RS23185 () | 70853..71335 | + | 483 | Protein_80 | hypothetical protein | - |
| H7Q98_RS23190 () | 71328..72185 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| H7Q98_RS23195 () | 73124..73766 | + | 643 | Protein_82 | CPBP family intramembrane metalloprotease | - |
| H7Q98_RS23200 () | 73859..74116 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H7Q98_RS23205 () | 74049..74450 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H7Q98_RS23210 () | 74699..75396 | + | 698 | Protein_85 | IS1 family transposase IS1R | Transposase |
| H7Q98_RS23215 () | 75413..75541 | + | 129 | Protein_86 | IS6 family transposase IS15DI | Transposase |
| H7Q98_RS23220 () | 75731..76546 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| H7Q98_RS23225 () | 76697..77401 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H7Q98_RS23230 () | 77462..78298 | - | 837 | WP_124783554.1 | hypothetical protein | ARG |
| H7Q98_RS23235 () | 78298..79101 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| H7Q98_RS23240 () | 79162..79977 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| H7Q98_RS23245 () | 80285..81136 | - | 852 | WP_000240536.1 | replication protein | - |
| H7Q98_RS23250 () | 81123..81842 | - | 720 | Protein_93 | AAA family ATPase | - |
| H7Q98_RS23255 () | 81892..82596 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H7Q98_RS23260 () | 82810..83670 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| H7Q98_RS23265 () | 83819..84496 | + | 678 | Protein_96 | IS4 family transposase IS10R | Transposase |
| H7Q98_RS23270 () | 84506..84877 | - | 372 | WP_035689358.1 | Transposon Tn10 TetD protein | VF |
| H7Q98_RS23275 () | 85010..85603 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| H7Q98_RS23280 () | 85716..86921 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| H7Q98_RS23285 () | 87003..87626 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| H7Q98_RS23290 () | 87604..88290 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| H7Q98_RS23295 () | 88298..88684 | - | 387 | WP_000460653.1 | hypothetical protein | - |
| H7Q98_RS23300 () | 88677..88997 | - | 321 | WP_000562367.1 | antibiotic biosynthesis monooxygenase | - |
| H7Q98_RS23305 () | 89441..90646 | + | 1206 | WP_000599533.1 | sodium/glutamate symporter | - |
| H7Q98_RS23310 () | 90877..90996 | + | 120 | Protein_105 | LysR family transcriptional regulator | - |
| H7Q98_RS23315 () | 91012..91899 | - | 888 | Protein_106 | IS4 family transposase IS10R | Transposase |
| H7Q98_RS23320 () | 92088..92453 | - | 366 | Protein_107 | Methyl-accepting chemotaxis protein McpU | VF |
| H7Q98_RS23325 () | 92449..92772 | + | 324 | Protein_108 | IS1380 family transposase ISEcp1 | Transposase |
| H7Q98_RS23330 () | 93022..93897 | + | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| H7Q98_RS23335 () | 93932..94900 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| H7Q98_RS23340 () | 94957..96054 | + | 1098 | Protein_111 | TonB-dependent receptor | - |
| H7Q98_RS23345 () | 96122..96658 | - | 537 | Protein_112 | PAS domain-containing protein | - |
| H7Q98_RS23350 () | 96968..97528 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| H7Q98_RS23355 () | 97532..100498 | + | 2967 | WP_182912536.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| H7Q98_RS23360 () | 100532..100858 | - | 327 | Protein_115 | IS4 family transposase IS10R | Transposase |
| H7Q98_RS23365 () | 101019..101678 | + | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| H7Q98_RS23370 () | 101879..102256 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| H7Q98_RS23375 () | 102431..103135 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H7Q98_RS23380 () | 103169..103330 | - | 162 | WP_174221953.1 | EAL domain-containing protein | - |
| H7Q98_RS23385 () | 103533..104546 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| H7Q98_RS23390 () | 104704..105177 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| H7Q98_RS23395 () | 105251..105955 | + | 705 | WP_182912537.1 | IS6-like element IS26 family transposase | - |
| H7Q98_RS23400 () | 106057..106536 | + | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| H7Q98_RS23405 () | 106606..109758 | - | 3153 | WP_000347934.1 | Efflux pump membrane transporter BepE | VF |
| H7Q98_RS23410 () | 109782..110957 | - | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| H7Q98_RS23415 () | 111277..111981 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| H7Q98_RS23420 () | 112316..112708 | + | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| H7Q98_RS23425 () | 113028..113414 | - | 387 | WP_063102497.1 | bleomycin binding protein | - |
| H7Q98_RS23430 () | 113608..114311 | - | 704 | Protein_129 | IS6 family transposase | - |
| H7Q98_RS23435 () | 114379..115677 | + | 1299 | Protein_130 | Tn3 family transposase TnpA_Tn3 | Transposase |
| H7Q98_RS23440 () | 115713..116573 | - | 861 | Protein_131 | IS66 family transposase ISEc8 | Transposase |
| H7Q98_RS23445 () | 116623..116970 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| H7Q98_RS23450 () | 116967..117347 | - | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| H7Q98_RS23455 () | 117423..118403 | - | 981 | WP_063099985.1 | NAD(P)-binding domain-containing protein | - |
| H7Q98_RS23460 () | 118400..118669 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| H7Q98_RS23465 () | 118671..119448 | - | 778 | Protein_136 | Gfo/Idh/MocA family oxidoreductase | - |
| H7Q98_RS23470 () | 119609..119845 | + | 237 | WP_001323890.1 | colicin V immunity protein | - |
| H7Q98_RS23475 () | 119823..120134 | + | 312 | WP_001259758.1 | colicin V | - |
| H7Q98_RS23480 () | 120304..122418 | - | 2115 | WP_001183604.1 | peptidase domain-containing ABC transporter | - |
| H7Q98_RS23485 () | 122393..123667 | - | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| H7Q98_RS23490 () | 124349..124546 | + | 198 | WP_001324224.1 | toxin-antitoxin system protein | Antitoxin Detail |
| H7Q98_RS23495 () | 124543..124725 | + | 183 | WP_000969988.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| H7Q98_RS23500 () | 124824..125132 | + | 309 | WP_000377483.1 | hypothetical protein | - |
| H7Q98_RS23505 () | 125692..126726 | + | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| H7Q98_RS23510 () | 127592..129769 | + | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| H7Q98_RS23515 () | 129814..130770 | - | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| H7Q98_RS23520 () | 130855..132084 | - | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| H7Q98_RS23525 () | 132188..135847 | - | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| H7Q98_RS23530 () | 135987..137102 | - | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| H7Q98_RS23535 () | 138338..139437 | - | 1100 | Protein_150 | IS481 family transposase ISKpn28 | Transposase |
| H7Q98_RS23540 () | 139991..140190 | + | 200 | Protein_151 | lysis protein | - |
| H7Q98_RS23545 () | 140248..140541 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| H7Q98_RS23550 () | 141121..141686 | + | 566 | Protein_153 | IS3 family transposase IS2 | Transposase |
| H7Q98_RS23560 () | 142927..143655 | + | 729 | Protein_155 | IS3 family transposase IS2 | Transposase |
| H7Q98_RS23565 () | 144897..146090 | + | 1194 | WP_000450494.1 | GTP-binding protein | - |
| H7Q98_RS23570 () | 146268..146417 | + | 150 | Protein_157 | IS3 family transposase IS2 | Transposase |
| H7Q98_RS23575 () | 146727..148116 | + | 1390 | Protein_158 | ISNCY family transposase ISKpn21 | Transposase |
| H7Q98_RS23580 () | 148351..149292 | + | 942 | WP_000974762.1 | hypothetical protein | - |
| H7Q98_RS23585 () | 149421..149615 | - | 195 | Protein_160 | IS200-IS605 family transposase IS200C | Transposase |
| H7Q98_RS23590 () | 150089..151459 | - | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| H7Q98_RS23595 () | 151463..153403 | - | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| H7Q98_RS23600 () | 153400..154587 | - | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| H7Q98_RS23605 () | 155568..155893 | + | 326 | Protein_164 | IS3 family transposase IS911 | Transposase |
| H7Q98_RS23610 () | 156041..157240 | - | 1200 | Protein_165 | IS3 family transposase IS629 | Transposase |
| H7Q98_RS23615 () | 157424..157582 | + | 159 | WP_001324039.1 | integrase core domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|